Occupational exposure to graphene and silica nanoparticles. Part II: pilot study to identify a panel of sensitive biomarkers of genotoxic, oxidative and inflammatory effects on suitable biological matrices.

abstract：:Passion fruit-like nano-architectures (NAs) are all-in-one platforms of increasing interest for the translation of metal nanoparticles into clinics. NAs are nature-inspired disassembling inorganic theranostics, which jointly combine most of the appealing behaviors of noble metal nanoparticles with their potential orga...

journal_title：Nanotoxicology

authors： d'Amora M,Cassano D,Pocoví-Martínez S,Giordani S,Voliani V

更新日期：2018-10-01 00:00:00

abstract：:To address the impact of cadmium sulphide nanoparticles (CdSNPs) of two different sizes (8 and 50 nm), Danio rerio zebrafish were dietary exposed to very low doses: 100 or 40 ng CdSNPs/day/g body weight for 36 or 60 days, respectively. The results obtained using RAPD-PCR genotoxicity test showed genomic alteration sin...

journal_title：Nanotoxicology

authors： Ladhar C,Geffroy B,Cambier S,Treguer-Delapierre M,Durand E,Brèthes D,Bourdineaud JP

更新日期：2014-09-01 00:00:00

abstract：:Silver nanoparticles (Ag-NPs) are used in a wide variety of products, prompting concerns regarding their potential environmental impacts. To accurately determine the toxicity of Ag-NPs it is necessary to differentiate between the toxicity of the nanoparticles themselves and the toxicity of ionic silver (Ag) released f...

journal_title：Nanotoxicology

authors： Sekine R,Khurana K,Vasilev K,Lombi E,Donner E

更新日期：2015-01-01 00:00:00

abstract：:Engineered nanoparticles are increasingly discharged into the environment. After discharge, these nanoparticles can interact with co-existing organic contaminants, resulting in a phenomena referred to as 'joint toxicity'. This study evaluated joint toxicities of TiO2 nanoparticles (TiO2NPs) with four different (atrazi...

journal_title：Nanotoxicology

authors： Zhang S,Deng R,Lin D,Wu F

更新日期：2017-01-01 00:00:00

abstract：:Nanosized zeolite particles are important materials for many applications in the field of nanotechnology. The possible adverse effects of these nanomaterials on human health have been scarcely investigated and remain largely unknown. This study reports the synthesis of nanozeolites Y and A with particle sizes of 25-10...

journal_title：Nanotoxicology

authors： Thomassen LC,Napierska D,Dinsdale D,Lievens N,Jammaer J,Lison D,Kirschhock CE,Hoet PH,Martens JA

更新日期：2012-08-01 00:00:00

abstract：:Deciphering the molecular basis of toxicology mechanism induced by nanoparticles (NPs) remains an essential challenge. Ion Beam Analysis (IBA) was applied in combination with Transmission Electron Microscopy and Confocal Microscopy to analyze human keratinocytes exposed to TiO(2)-NPs. Investigating chemical elemental ...

journal_title：Nanotoxicology

authors： Simon M,Barberet P,Delville MH,Moretto P,Seznec H

更新日期：2011-06-01 00:00:00

abstract：:The rapid proliferation of silver nanoparticles (AgNP) in industry and the environment requires realistic toxicity assessments based on approaches that consider the biological complexity of ecosystems. Here we assessed the acute toxicity of carbonate-coated AgNP and, for comparison, AgNO3 (Ag(+)) by using a model syst...

journal_title：Nanotoxicology

authors： Tlili A,Cornut J,Behra R,Gil-Allué C,Gessner MO

更新日期：2016-08-01 00:00:00

abstract：:The levels of exposure and internal doses of nanomaterials are becoming more and more important for estimating the health effects resulting from exposure to nanomaterials. Health surveillance can be used as an indicator of whether exposure is occurring, rather than in determining if levels of exposure are safe. We hav...

journal_title：Nanotoxicology

authors： Lee JH,Mun J,Park JD,Yu IJ

更新日期：2012-09-01 00:00:00

abstract：:We systematically investigated how the combinations of size, shape and the natural organic matter (NOM)-ecocorona of gold (Au) engineered nanoparticles (ENPs) influence the attachment of the particles to algae and physical toxicity to the cells. Spherical (10, 60 and 100 nm), urchin-shaped (60 nm), rod-shaped (10 × 45...

journal_title：Nanotoxicology

authors： Abdolahpur Monikh F,Arenas-Lago D,Porcal P,Grillo R,Zhang P,Guo Z,Vijver MG,J G M Peijnenburg W

更新日期：2020-04-01 00:00:00

abstract：:We evaluated and compared the pulmonary clearance kinetics and extrapulmonary translocations of seven titanium dioxide (TiO2) nano- and submicron particles with different characteristics, including size, shape and surface coating. Varying doses of TiO2 nano- and submicron particles dispersed in 0.2% disodium phosphate...

journal_title：Nanotoxicology

authors： Shinohara N,Oshima Y,Kobayashi T,Imatanaka N,Nakai M,Ichinose T,Sasaki T,Kawaguchi K,Zhang G,Gamo M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The enormous physicochemical and structural diversity of metal oxide nanoparticles (MeONPs) poses significant challenges to the testing of their biological uptake, biodistribution, and effects that can be used to develop understanding of key nano-bio modes of action. This has generated considerable uncertain...

journal_title：Nanotoxicology

authors： Mu Y,Wu F,Zhao Q,Ji R,Qie Y,Zhou Y,Hu Y,Pang C,Hristozov D,Giesy JP,Xing B

更新日期：2016-11-01 00:00:00

abstract：:In the present study, ZnS and ZnO quantum dots (QDs) were synthesized via an all-aqueous process with polyethylene glycol (PEG) chains on their surface, and their toxicity as well as biodistribution were evaluated. No haemolysis occurred at a high concentration of 1600 µg/mL in vitro haemolytic assay, which demonstrat...

journal_title：Nanotoxicology

authors： Yang Y,Lan J,Xu Z,Chen T,Zhao T,Cheng T,Shen J,Lv S,Zhang H

更新日期：2014-02-01 00:00:00

abstract：:Titanium dioxide nanoparticles (TiO2 NPs) have shown great adsorption capacity for arsenic (As); however, the potential impact of TiO2 NPs on the behavior and toxic responses of As remains largely unexplored. In the present study, we focused on the physicochemical interaction between TiO2 NPs and As(III) to clarify th...

journal_title：Nanotoxicology

authors： Wang X,Liu Y,Wang J,Nie Y,Chen S,Hei TK,Deng Z,Wu L,Zhao G,Xu A

更新日期：2017-10-01 00:00:00

abstract：:Despite the increasing commercial use of nanoparticles, little is known about their effects on placental inflammation and pregnancy complications. In this study, nanosilica (NS) particles upregulated the inflammasome component nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain-containing...

journal_title：Nanotoxicology

authors： Shirasuna K,Usui F,Karasawa T,Kimura H,Kawashima A,Mizukami H,Ohkuchi A,Nishimura S,Sagara J,Noda T,Ozawa K,Taniguchi S,Takahashi M

更新日期：2015-01-01 00:00:00

abstract：:Here, we present evidence on complete transformation of ZnO and CuO nanoparticles, which are among the most heavily studied metal oxide particles, during 24 h in vitro toxicological testing with human T-lymphocytes. Synchrotron radiation-based X-ray absorption near edge structure (XANES) spectroscopy results revealed ...

journal_title：Nanotoxicology

authors： Ivask A,Scheckel KG,Kapruwan P,Stone V,Yin H,Voelcker NH,Lombi E

更新日期：2017-03-01 00:00:00

abstract：:Growing experimental evidences suggest the existence of direct relationships between the surface chemistry of nanomaterials and their biological effects. Herein, we have employed computational approaches to design a set of biologically active carbon nanotubes (CNTs) with controlled protein binding and cytotoxicity. Qu...

journal_title：Nanotoxicology

authors： Fourches D,Pu D,Li L,Zhou H,Mu Q,Su G,Yan B,Tropsha A

更新日期：2016-01-01 00:00:00

abstract：:Multi-walled carbon nanotubes (MWCNTs) are one of the most widely used types of novel nano-fiber materials. The aim of this study was to establish an experimental system based on actual exposure dosage and environments and explore the roles and mechanisms of inflammation in the malignant transformation of pleural meso...

journal_title：Nanotoxicology

authors： Huang X,Tian Y,Shi W,Chen J,Yan L,Ren L,Zhang X,Zhu J

更新日期：2020-09-01 00:00:00

abstract：:Dendrimers are nanosized hyperbranched polymers synthesized through an iterative step-by-step process; their size and structure are perfectly controlled, and they are widely used for biomedical purposes. Previously, we showed that a phosphorous-based dendrimer capped with anionic AzaBisPhosphonate groups (so-called AB...

journal_title：Nanotoxicology

authors： Fruchon S,Mouriot S,Thiollier T,Grandin C,Caminade AM,Turrin CO,Contamin H,Poupot R

更新日期：2015-05-01 00:00:00

abstract：:In our previous studies of nanocalcium carbonate, in which we performed physicochemical analysis, genotoxicity, acute single-dose and repeated-dose 14-day oral toxicity testings in Sprague-Dawley (SD) rats, nanocalcium carbonate did not show a difference in toxicity compared to vehicle control. Here, we provide the fi...

journal_title：Nanotoxicology

authors： Sung JH,Park SJ,Jeong MS,Song KS,Ahn KS,Ryu HR,Lee H,Song MR,Cho MH,Kim JS

更新日期：2015-01-01 00:00:00

abstract：:The whitening and opacifying properties of titanium dioxide (TiO2) are commonly exploited when it is used as a food additive (E171). However, the safety of this additive can be questioned as TiO2 nanoparticles (TiO2-NPs) have been classed at potentially toxic. This study aimed to shed some light on the mechanisms behi...

journal_title：Nanotoxicology

authors： Dorier M,Béal D,Marie-Desvergne C,Dubosson M,Barreau F,Houdeau E,Herlin-Boime N,Carriere M

更新日期：2017-08-01 00:00:00

abstract：:Sunscreens containing metal oxide nanoparticles appear transparent on the skin and provide excellent protection against sunburn caused by UV radiation. While it is likely that nanoparticles remain on the surface of the skin of healthy adult humans, and thus are considered safe for use in sunscreens, there has been no ...

journal_title：Nanotoxicology

authors： Osmond MJ,McCall MJ

更新日期：2010-03-01 00:00:00

abstract：:Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In the present study mice were exposed to PbO nanoparticles (PbONP; 192.5 µg/m3; 1.93 × 106 particles/cm3) for 2, 5 and 13 weeks through continuous inhalation. The...

journal_title：Nanotoxicology

authors： Bláhová L,Nováková Z,Večeřa Z,Vrlíková L,Dočekal B,Dumková J,Křůmal K,Mikuška P,Buchtová M,Hampl A,Hilscherová K,Bláha L

更新日期：2020-03-01 00:00:00

abstract：:The number of engineered nanomaterials (ENMs) being exploited commercially is growing rapidly, due to the novel properties they exhibit. Clearly, it is important to understand and minimize any risks to health or the environment posed by the presence of ENMs. Data-driven models that decode the relationships between the...

journal_title：Nanotoxicology

authors： Oksel C,Winkler DA,Ma CY,Wilkins T,Wang XZ

更新日期：2016-09-01 00:00:00

abstract：:Boron and boron nitride nanotubes (BNNTs) are increasingly used in different industrial fields and, potentially, in some biomedical areas. As occurs with other nanomaterials (NMs), to increase our knowledge on their potential health hazards is a priority. Although in vitro approaches are a routine in getting biologica...

journal_title：Nanotoxicology

authors： Demir E,Marcos R

更新日期：2018-10-01 00:00:00

abstract：:The effect of non-functionalized and amino-functionalized multiwall carbon nanotube (CNT) exposure, as well as the impact of CNT presence on coexistent pesticide accumulation, was investigated in lettuce (Lactuca sativa L.). Lettuce seeds were sown directly into CNT-amended vermiculite (1000 mg L(-1)) to monitor phyto...

journal_title：Nanotoxicology

authors： Hamdi H,De La Torre-Roche R,Hawthorne J,White JC

更新日期：2015-03-01 00:00:00

abstract：:Here, we evaluate the extent of sorption of silver nanoparticles (AgNPs) with different primary sizes (30 and 70 nm) and surface properties (branched polyethylene imine, "bPEI" and citrate coating) to laboratory plastic during (eco)toxicological testing. Under conditions of algal growth inhibition assay, up to 97% of ...

journal_title：Nanotoxicology

authors： Malysheva A,Ivask A,Hager C,Brunetti G,Marzouk ER,Lombi E,Voelcker NH

更新日期：2016-01-01 00:00:00

abstract：:Effects of maternal pulmonary exposure to carbon black (Printex 90) on gestation, lactation and DNA strand breaks were evaluated. Time-mated C57BL/6BomTac mice were exposed by inhalation to 42 mg/m(3) Printex 90 for 1 h/day on gestation days (GD) 8-18, or by four intratracheal instillations on GD 7, 10, 15 and 18, wit...

journal_title：Nanotoxicology

authors： Jackson P,Hougaard KS,Boisen AM,Jacobsen NR,Jensen KA,Møller P,Brunborg G,Gutzkow KB,Andersen O,Loft S,Vogel U,Wallin H

更新日期：2012-08-01 00:00:00

abstract：:Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials. Following oral exposure, AgNPs can accumulate in various organs including kidneys where they show gender specific accumulation. There is limited information on their effect on renal system following long-term animal exposure especially at the ...

journal_title：Nanotoxicology

authors： Tiwari R,Singh RD,Khan H,Gangopadhyay S,Mittal S,Singh V,Arjaria N,Shankar J,Roy SK,Singh D,Srivastava V

更新日期：2017-06-01 00:00:00

abstract：:Copper nanoparticles (Cu NPs) have various uses, including as additives in polymers/plastics, lubricants for metallic coating, and biomedical applications. We investigated the role of transforming growth factor (TGF)-β1 signaling in hepatic damage caused by Cu NPs and explored the effects of a 28-day repeated oral adm...

journal_title：Nanotoxicology

authors： Lee IC,Ko JW,Park SH,Shin NR,Shin IS,Moon C,Kim SH,Yun WK,Kim HC,Kim JC

更新日期：2018-08-01 00:00:00

abstract：:The printer is one of the most common office equipment. Recently, it was reported that toner formulations for printing equipment constitute nano-enabled products (NEPs) and contain engineered nanomaterials (ENMs) that become airborne during printing. To date, insufficient research has been performed to understand the ...

journal_title：Nanotoxicology

authors： Sisler JD,Pirela SV,Friend S,Farcas M,Schwegler-Berry D,Shvedova A,Castranova V,Demokritou P,Qian Y

更新日期：2015-01-01 00:00:00