Comparative cytotoxicity induced by bulk and nanoparticulated ZnO in the fish and human hepatoma cell lines PLHC-1 and Hep G2.

abstract：:The whitening and opacifying properties of titanium dioxide (TiO2) are commonly exploited when it is used as a food additive (E171). However, the safety of this additive can be questioned as TiO2 nanoparticles (TiO2-NPs) have been classed at potentially toxic. This study aimed to shed some light on the mechanisms behi...

journal_title：Nanotoxicology

authors： Dorier M,Béal D,Marie-Desvergne C,Dubosson M,Barreau F,Houdeau E,Herlin-Boime N,Carriere M

更新日期：2017-08-01 00:00:00

abstract：:If engineered nanomaterials are released into the environment, some are likely to end up associated with the food of animals due to aggregation and sorption processes. However, few studies have considered dietary exposure of nanomaterials. Here we show that zinc (Zn) from isotopically modified (67)ZnO particles is eff...

journal_title：Nanotoxicology

authors： Croteau MN,Dybowska AD,Luoma SN,Valsami-Jones E

更新日期：2011-03-01 00:00:00

abstract：:Abstract To examine gold nanoparticle reprotoxicity, bovine spermatozoa were challenged with ligand-free or oligonucleotide-conjugated gold nanoparticles synthesized purely without any surfactants by laser ablation. Sperm motility declined at nanoparticle mass dose of 10 µg/ml (corresponding to ∼14 000 nanoparticles p...

journal_title：Nanotoxicology

authors： Taylor U,Barchanski A,Petersen S,Kues WA,Baulain U,Gamrad L,Sajti L,Barcikowski S,Rath D

更新日期：2014-08-01 00:00:00

abstract：:Despite the increasing commercial use of nanoparticles, little is known about their effects on placental inflammation and pregnancy complications. In this study, nanosilica (NS) particles upregulated the inflammasome component nucleotide-binding oligomerization domain-like receptor (NLR) family pyrin domain-containing...

journal_title：Nanotoxicology

authors： Shirasuna K,Usui F,Karasawa T,Kimura H,Kawashima A,Mizukami H,Ohkuchi A,Nishimura S,Sagara J,Noda T,Ozawa K,Taniguchi S,Takahashi M

更新日期：2015-01-01 00:00:00

abstract：:Engineered nanoparticles are increasingly used in medical applications and day-to-day consumer products, leading to concerns about the potential environmental and human health impacts. Silver nanoparticles are particularly prevalent because of their use as anti-bacterial agents in many commonly available products. Nan...

journal_title：Nanotoxicology

authors： Kermanizadeh A,Chauché C,Balharry D,Brown DM,Kanase N,Boczkowski J,Lanone S,Stone V

更新日期：2014-08-01 00:00:00

abstract：:Although the production of engineered nanoparticles increases our knowledge of toxicity and mechanisms of bioactivity during relevant exposures is lacking. In the present study mice were exposed to PbO nanoparticles (PbONP; 192.5 µg/m3; 1.93 × 106 particles/cm3) for 2, 5 and 13 weeks through continuous inhalation. The...

journal_title：Nanotoxicology

authors： Bláhová L,Nováková Z,Večeřa Z,Vrlíková L,Dočekal B,Dumková J,Křůmal K,Mikuška P,Buchtová M,Hampl A,Hilscherová K,Bláha L

更新日期：2020-03-01 00:00:00

abstract：:In the present study, ZnS and ZnO quantum dots (QDs) were synthesized via an all-aqueous process with polyethylene glycol (PEG) chains on their surface, and their toxicity as well as biodistribution were evaluated. No haemolysis occurred at a high concentration of 1600 µg/mL in vitro haemolytic assay, which demonstrat...

journal_title：Nanotoxicology

authors： Yang Y,Lan J,Xu Z,Chen T,Zhao T,Cheng T,Shen J,Lv S,Zhang H

更新日期：2014-02-01 00:00:00

abstract：:With the increased production and widespread commercial use of silver nanoparticles (AgNPs), human and environmental exposures to silver nanoparticles are inevitably increasing. In particular, persons manufacturing and handling silver nanoparticles and silver nanoparticle containing products are at risk of exposure, p...

journal_title：Nanotoxicology

authors： Weldon BA,M Faustman E,Oberdörster G,Workman T,Griffith WC,Kneuer C,Yu IJ

更新日期：2016-09-01 00:00:00

abstract：:ZnO nanoparticles (NPs) elicit significant adverse effects in various cell types, organisms and in the environment. The toxicity of nanoscale ZnO has often been ascribed to the release of zinc ions from the NPs but it is not yet understood to which extent these ions contribute to ZnO NP toxicity and what are the under...

journal_title：Nanotoxicology

authors： Buerki-Thurnherr T,Xiao L,Diener L,Arslan O,Hirsch C,Maeder-Althaus X,Grieder K,Wampfler B,Mathur S,Wick P,Krug HF

更新日期：2013-06-01 00:00:00

abstract：:Foodborne nanoparticles (NPs) refer to the nanostructures generated during food processing, rather than the man-made nano-structural additives that are added to improve the property of food. In this research, discovery of fluorescent NPs in roasted pork was reported at different temperature of 180, 230, and 280 °C. Th...

journal_title：Nanotoxicology

authors： Zhao X,Shan S,Li J,Cao L,Lv J,Tan M

更新日期：2019-12-01 00:00:00

abstract：:Understanding the relationship between adverse exposure events and specific material properties will facilitate predictive classification of carbon nanotubes (CNTs) according to their mechanisms of action, and a safe-by-design approach for the next generation of CNTs. Mass-spectrometry-based proteomics is a reliable t...

journal_title：Nanotoxicology

authors： Ndika JDT,Sund J,Alenius H,Puustinen A

更新日期：2018-08-01 00:00:00

abstract：:Titanium dioxide nanoparticles (TiO2 NPs) have shown great adsorption capacity for arsenic (As); however, the potential impact of TiO2 NPs on the behavior and toxic responses of As remains largely unexplored. In the present study, we focused on the physicochemical interaction between TiO2 NPs and As(III) to clarify th...

journal_title：Nanotoxicology

authors： Wang X,Liu Y,Wang J,Nie Y,Chen S,Hei TK,Deng Z,Wu L,Zhao G,Xu A

更新日期：2017-10-01 00:00:00

abstract：:Copper oxide nanoparticles (CuO NPs) have severe nano-toxic effects on organisms. Limited data is available on influence of CuO NPs on plant cells. Here, the molecular mechanisms involved in the toxicity of CuO NPs are studied. Exposure to CuO NPs significantly increased copper content in roots (0.062-0.325 mg/g FW), ...

journal_title：Nanotoxicology

authors： Jia H,Chen S,Wang X,Shi C,Liu K,Zhang S,Li J

更新日期：2020-02-01 00:00:00

abstract：:Single-walled carbon nanotubes (SWCNTs) are widely used in industrial and medical sectors, and the increasing exposure of SWCNTs necessitates the studies of their potential environmental and health effects. Considerable efforts have been made to improve the dispersion of SWCNTs by chemical modifications. However, the ...

journal_title：Nanotoxicology

authors： Dong PX,Wan B,Guo LH

更新日期：2012-05-01 00:00:00

abstract：:Boron and boron nitride nanotubes (BNNTs) are increasingly used in different industrial fields and, potentially, in some biomedical areas. As occurs with other nanomaterials (NMs), to increase our knowledge on their potential health hazards is a priority. Although in vitro approaches are a routine in getting biologica...

journal_title：Nanotoxicology

authors： Demir E,Marcos R

更新日期：2018-10-01 00:00:00

abstract：:Inhalation of zinc oxide nanoparticles (ZnONP) has potential health impact. Because zinc ion may involve in the toxicity of ZnONP, we compared adverse effects of inhaled aerosolized ZnONP and zinc nitrate in mice. Aerosolized ZnONP and zinc nitrate were well-dispersed in the inhalation chamber. Inhalation of 0.86 mg/m...

journal_title：Nanotoxicology

authors： Chen JK,Ho CC,Chang H,Lin JF,Yang CS,Tsai MH,Tsai HT,Lin P

更新日期：2015-02-01 00:00:00

abstract：:Due to the increasing use of nanometric cerium oxide in applications, concerns about the toxicity of these particles have been raised and have resulted in a large number of studies. We report here on the interactions between 7 nm anionically charged cerium oxide particles and living mammalian cells. By a modification ...

journal_title：Nanotoxicology

authors： Ould-Moussa N,Safi M,Guedeau-Boudeville MA,Montero D,Conjeaud H,Berret JF

更新日期：2014-11-01 00:00:00

abstract：:We aimed to create transgenic (Tg) mice engineered for magnetic resonance imaging (MRI). To ascertain if MagA expression contributes to oxidative stress and iron metabolism, we report the generation of Tg mice in which ubiquitous expression of MagA can be detected by MRI in vivo. Expression of MagA in diverse tissues ...

journal_title：Nanotoxicology

authors： Guan X,Jiang X,Yang C,Tian X,Li L

更新日期：2016-01-01 00:00:00

abstract：:Cellular adaptation is the dynamic response of a cell to adverse changes in its intra/extra cellular environment. The aims of this study were to investigate the role of: (i) the glutathione antioxidant system, and (ii) the transcription factor EB (TFEB), a newly revealed master regulator of lysosome biogenesis, in cel...

journal_title：Nanotoxicology

authors： Neibert KD,Maysinger D

更新日期：2012-05-01 00:00:00

abstract：:We evaluated and compared the pulmonary clearance kinetics and extrapulmonary translocations of seven titanium dioxide (TiO2) nano- and submicron particles with different characteristics, including size, shape and surface coating. Varying doses of TiO2 nano- and submicron particles dispersed in 0.2% disodium phosphate...

journal_title：Nanotoxicology

authors： Shinohara N,Oshima Y,Kobayashi T,Imatanaka N,Nakai M,Ichinose T,Sasaki T,Kawaguchi K,Zhang G,Gamo M

更新日期：2015-01-01 00:00:00

abstract：:Here, we present evidence on complete transformation of ZnO and CuO nanoparticles, which are among the most heavily studied metal oxide particles, during 24 h in vitro toxicological testing with human T-lymphocytes. Synchrotron radiation-based X-ray absorption near edge structure (XANES) spectroscopy results revealed ...

journal_title：Nanotoxicology

authors： Ivask A,Scheckel KG,Kapruwan P,Stone V,Yin H,Voelcker NH,Lombi E

更新日期：2017-03-01 00:00:00

abstract：:Our group already demonstrated that europium hydroxide nanorods (EHNs) show none or mild toxicity in C57BL/6 mice even at high dose and exhibited excellent pro-angiogenic activity towards in vitro and in vivo models. In the present study, we evaluated the in vivo cytogenetic toxicity of intraperitoneally administered ...

journal_title：Nanotoxicology

authors： Bollu VS,Nethi SK,Dasari RK,Rao SS,Misra S,Patra CR

更新日期：2016-01-01 00:00:00

abstract：:Cadmium (Cd) is a component in quantum dot 705 (QD705). Whether QD705 behaves similar to Cd in vivo is of great concern. We compared the distributional kinetics of cadmium chloride (CdCl(2)) and QD705 in mice after intravenous injection. QD705 showed a longer plasma and body retention than CdCl(2) and could be detecte...

journal_title：Nanotoxicology

authors： Yeh TK,Wu JP,Chang LW,Tsai MH,Chang WH,Tsai HT,Yang CS,Lin P

更新日期：2011-03-01 00:00:00

abstract：:Titanium-dioxide nanoparticles (TiO2-NPs) are increasingly released in agricultural soils through, e.g. biosolids, irrigation or nanoagrochemicals. Soils are submitted to a wide range of concentrations of TiO2-NPs depending on the type of exposure. However, most studies have assessed the effects of unrealistically hig...

journal_title：Nanotoxicology

authors： Simonin M,Martins JM,Le Roux X,Uzu G,Calas A,Richaume A

更新日期：2017-03-01 00:00:00

abstract：:Silver nanoparticles (AgNPs) are one of the most widely used nanomaterials. Following oral exposure, AgNPs can accumulate in various organs including kidneys where they show gender specific accumulation. There is limited information on their effect on renal system following long-term animal exposure especially at the ...

journal_title：Nanotoxicology

authors： Tiwari R,Singh RD,Khan H,Gangopadhyay S,Mittal S,Singh V,Arjaria N,Shankar J,Roy SK,Singh D,Srivastava V

更新日期：2017-06-01 00:00:00

abstract：:This study aims to assess the effects of Ag particles synthesised by a chemical (Ag 20, 200 nm) and biological method (Ag 23, 27 nm) in aquatic organisms: the bacterium Vibrio fischeri, the alga Desmodesmus subspicatus and the crustacean Daphnia magna. Ag particles exerted toxic effects in all organisms studied with A...

journal_title：Nanotoxicology

authors： Georgantzopoulou A,Balachandran YL,Rosenkranz P,Dusinska M,Lankoff A,Wojewodzka M,Kruszewski M,Guignard C,Audinot JN,Girija S,Hoffmann L,Gutleb AC

更新日期：2013-11-01 00:00:00

abstract：:The widespread increase in the production and use of nanomaterials has increased the potential for nanoparticle exposure; however, the biological effects of nanoparticle inhalation are poorly understood. Rats were exposed to nanosized titanium dioxide aerosols (10 μg lung burden); at 24 h post-exposure, the spinotrape...

journal_title：Nanotoxicology

authors： Knuckles TL,Yi J,Frazer DG,Leonard HD,Chen BT,Castranova V,Nurkiewicz TR

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The enormous physicochemical and structural diversity of metal oxide nanoparticles (MeONPs) poses significant challenges to the testing of their biological uptake, biodistribution, and effects that can be used to develop understanding of key nano-bio modes of action. This has generated considerable uncertain...

journal_title：Nanotoxicology

authors： Mu Y,Wu F,Zhao Q,Ji R,Qie Y,Zhou Y,Hu Y,Pang C,Hristozov D,Giesy JP,Xing B

更新日期：2016-11-01 00:00:00

abstract：:The fiber-like shape of multi-walled carbon nanotubes (MWCNTs) is reminiscent of asbestos, suggesting they pose similar health hazards when inhaled, including pulmonary fibrosis and mesothelioma. Mice deficient in the tumor suppressor p53 are susceptible to carcinogenesis. However, the chronic pathologic effect of MWC...

journal_title：Nanotoxicology

authors： Duke KS,Thompson EA,Ihrie MD,Taylor-Just AJ,Ash EA,Shipkowski KA,Hall JR,Tokarz DA,Cesta MF,Hubbs AF,Porter DW,Sargent LM,Bonner JC

更新日期：2018-11-01 00:00:00

abstract：:Little information exists on the toxicological hazards associated to organo-modified clays. We evaluated the cytotoxicity of a series of pristine and organo-modified nanoclays in different cell lines. The calculated IC50 values for cell viability ranged from 1.4 to 47 µg/mL for the six organoclays used and were above ...

journal_title：Nanotoxicology

authors： Janer G,Fernández-Rosas E,Mas del Molino E,González-Gálvez D,Vilar G,López-Iglesias C,Ermini V,Vázquez-Campos S

更新日期：2014-05-01 00:00:00