听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Journal of Orthopaedic Translation期刊下所有文献
  • Molecular mechanisms of osteogenesis and antibacterial activity of Cu-bearing Ti alloy in a bone defect model with infection in vivo.

    abstract:Objective:The antibacterial activity of copper (Cu)-alloy biomaterials has shown a great potential in clinical application. Here, we evaluated the osteogenesis and antibacterial effects of Ti6Al4V-6.5wt%Cu alloy in an in vivo model of infected bone defects and determine their responsible proteins and pathways using pro...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2020.10.004

    authors: Yang J,Qin H,Chai Y,Zhang P,Chen Y,Yang K,Qin M,Zhang Y,Xia H,Ren L,Yu B

    更新日期:2020-12-28 00:00:00

  • Impact of COVID-19 on orthopaedic clinical service, education and research in a university hospital.

    abstract::The medical system of Hong Kong has been heavily affected by COVID-19. Adaptations are necessary to continue clinical care, education, and research, while minimising the risk of infection of our staff and students. Here, we report our early experience in response to the challenge posed by the COVID-19 pandemic. The t...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2020.08.001

    authors: Ong MT,Ling SK,Wong RM,Ho KK,Chow SK,Cheung LW,Yung PS

    更新日期:2020-11-01 00:00:00

  • Higher stability and more predictive fixation with the Femoral Neck System versus Hansson Pins in femoral neck fractures Pauwels II.

    abstract:Objectives:To evaluate the biomechanical performance of the Femoral Neck System (FNS) versus the Hansson Pin System (Hansson Pins) with two parallel pins in a Pauwels II femoral neck fracture model with posterior comminution. Methods:Forty-degree Pauwels II femoral neck fractures AO 31-B2.1 with 15° posterior wedge we...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2020.06.002

    authors: Schopper C,Zderic I,Menze J,Müller D,Rocci M,Knobe M,Shoda E,Richards G,Gueorguiev B,Stoffel K

    更新日期:2020-07-22 00:00:00

  • Defactinib attenuates osteoarthritis by inhibiting positive feedback loop between H-type vessels and MSCs in subchondral bone.

    abstract:Background:Abnormal bone formation in subchondral bone resulting from uncoupled bone remodeling is considered a central feature in osteoarthritis (OA) pathogenesis. H-type vessels can couple angiogenesis and osteogenesis. We previously revealed that elevated H-type vessels in subchondral bone were correlated with OA an...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2020.04.008

    authors: Hu Y,Wu H,Xu T,Wang Y,Qin H,Yao Z,Chen P,Xie Y,Ji Z,Yang K,Chai Y,Zhang X,Yu B,Cui Z

    更新日期:2020-05-19 00:00:00

  • Antibiotic containing bone cement in prevention of hip and knee prosthetic joint infections: A systematic review and meta-analysis.

    abstract:Background:Prosthetic joint infection (PJI) is the most serious total joint arthroplasty (TJA) complication despite several aseptic and antiseptic preventive measures. There is no clear evidence or even consensus, whether antibiotic-loaded bone cement (ALBC) should be used, in addition to systemic short-term routine an...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2020.04.005

    authors: Sebastian S,Liu Y,Christensen R,Raina DB,Tägil M,Lidgren L

    更新日期:2020-05-08 00:00:00

  • Mesenchymal stem cells in knee osteoarthritis treatment: A systematic review and meta-analysis.

    abstract::Stem cells are considered to be one of the greatest potential treatments to cure degenerative diseases. Stem cells injection for knee osteoarthritis (OA) is still a relatively new treatment and has not yet gained popularity. So, the effectiveness, safety and potential of mesenchymal stem cells (MSCs) for knee OA treat...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2020.03.015

    authors: Song Y,Zhang J,Xu H,Lin Z,Chang H,Liu W,Kong L

    更新日期:2020-04-27 00:00:00

  • Exosomes derived from umbilical cord mesenchymal stem cells in mechanical environment show improved osteochondral activity via upregulation of LncRNA H19.

    abstract:Background:Exosomes derived from stem cells have been demonstrated to be good candidates for the treatment of osteochondral injury. Our previous studies have demonstrated that mechanical stimulation could be crucial for the secretion of exosomes derived from umbilical cord mesenchymal stem cells (U-MSCs). Therefore, we...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2020.03.005

    authors: Yan L,Liu G,Wu X

    更新日期:2020-04-03 00:00:00

  • Evaluation of animal models and methods for assessing shoulder function after rotator cuff tear: A systematic review.

    abstract:Background and objective:Restoring the shoulder function is a crucial demand of patients with rotator cuff (RC) tears. Most preclinical studies only focused on biological and mechanical measurements. Functional assessment was less investigated in the preclinical studies. This study aims to review the literature of shou...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2020.02.012

    authors: Liu Y,Fu SC,Leong HT,Ling SK,Oh JH,Yung PS

    更新日期:2020-03-23 00:00:00

  • Machine learning-based identification of hip arthroplasty designs.

    abstract:Background:The purposes of this study were to develop a machine learning-based implant recognition program and to verify its accuracy. Methods:Postoperative anteroposterior (AP) X-rays (≥300 dpi) were collected of patients who underwent total hip arthroplasty. X-rays with a wire or plate added and those without a true...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.11.004

    authors: Kang YJ,Yoo JI,Cha YH,Park CH,Kim JT

    更新日期:2019-12-20 00:00:00

  • Percutaneous short-segment pedicle instrumentation assisted with O-arm navigation in the treatment of thoracolumbar burst fractures.

    abstract:Object:To compare the clinical and radiological outcomes of O-arm navigation assisted percutaneous pedicle fixation and open freehand pedicle fixation in treatment of AO type A3 thoracolumbar burst fractures (TBFs) without neurological deficit. Methods:This retrospective study involved 72 patients with type A3 TBFs wh...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.11.002

    authors: Yang P,Chen K,Zhang K,Sun J,Yang H,Mao H

    更新日期:2019-12-05 00:00:00

  • Diffusion of neutral solutes within human osteoarthritic cartilage: Effect of loading patterns.

    abstract:Objective:Variation of the solute diffusion within articular cartilage is an important feature of osteoarthritis (OA) progression. For in vitro study of monitoring of the diffusion process, it is essential to simulate physiological conditions as much as possible. Our objective was to investigate the effects of loading ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.10.013

    authors: Meng H,Quan Q,Yuan X,Zheng Y,Peng J,Guo Q,Wang A,Lu S

    更新日期:2019-11-20 00:00:00

  • Subchondral bone deterioration in femoral heads in patients with osteoarthritis secondary to hip dysplasia: A case-control study.

    abstract:Objectives:Residual hip dysplasia is the most common underlying condition leading to secondary osteoarthritis (OA) of the hip. Subchondral bone alterations in OA secondary to hip dysplasia (HD-OA) are poorly investigated. The aim of the present study was to analyse the microarchitecture, bone remodelling and pathologic...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.10.014

    authors: Li G,Chen L,Zheng Q,Ma Y,Zhang C,Zheng MH

    更新日期:2019-11-20 00:00:00

  • Development of generic Asian pelvic bone models using CT-based 3D statistical modelling.

    abstract:Background/Objective:Artificial bone models (ABMs) are used in orthopaedics for research of biomechanics, development of implants and educational purposes. Most of the commercially available ABMs approximate the morphology of Europeans, but they may not depict the Asian anatomy. Therefore, our aim was to develop the fi...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.10.004

    authors: Ahrend MD,Noser H,Shanmugam R,Burr F,Kamer L,Kamarul T,Hügli H,Nagy A,Richards RG,Gueorguiev-Rüegg B

    更新日期:2019-11-04 00:00:00

  • Design of a new magnesium-based anterior cruciate ligament interference screw using finite element analysis.

    abstract:Background/objective:In anterior cruciate ligament ​reconstruction, a tendon graft, anchored by interference screws (IFSs), is frequently used as a replacement for the damaged ligament. Generally, IFSs are classified as being either metallic or polymeric. Metallic screws have sharp threads that lacerate the graft, prev...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.09.003

    authors: Mau JR,Hawkins KM,Woo SL,Kim KE,McCullough MBA

    更新日期:2019-10-14 00:00:00

  • Early degeneration of the meniscus revealed by microbiomechanical alteration in a rabbit anterior cruciate ligament transection model.

    abstract:Background:The microbiomechanical properties of the meniscus influence the cell response to the surrounding biomechanical environment ​and are beneficial to understand meniscus repairing and healing. To date, however, this information remains ambiguous. This study aims to characterise the microbiomechanical properties ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.06.003

    authors: Liang T,Jiang HY,Li HT,Che YJ,Yang HL,An KN,Luo ZP

    更新日期:2019-08-08 00:00:00

  • Treatment of femoral neck nonunion with a new fixation construct through the Watson-Jones approach.

    abstract:Objective:The aim of the study is to explore the clinical effect of a dynamic condylar screw (DCS) system, medial anatomical buttress plate (MABP), and autogenous iliac bone graft through the Watson-Jones approach in the treatment of femoral neck nonunion. Methods:This prospective study included 15 patients (12 men an...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.04.004

    authors: Chen H,Li J,Chang Z,Liang X,Tang P

    更新日期:2019-04-28 00:00:00

  • Characterisation of multipotent stem cells from human peripheral blood using an improved protocol.

    abstract:Background:A promising approach of bone repair is to use stem cells, such as mesenchymal stem cells (MSCs). Seeking available source of MSCs still remains a great challenge in tissue engineering and cell therapy. Peripheral blood (PB) emerges as an alternative source of MSCs which can be easily acquired with minimal in...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2019.02.003

    authors: Lin W,Xu L,Lin S,Shi L,Wang B,Pan Q,Lee WYW,Li G

    更新日期:2019-03-07 00:00:00

  • The correlation between activity level, serum-ion concentrations and pseudotumours in patients with metal-on-metal hip articulations and metal-on-polyethylene total hip articulations.

    abstract:Purpose:Young and physically active patients have mainly received metal-on-metal (MoM) total hip arthroplasty (THA) and resurfacing hip arthroplasty (RHA). However, the correlation between daily physical activity (PA) levels, serum-ion concentrations of chromium and cobalt and pseudotumours formation of patients who un...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2018.11.001

    authors: Hjorth MH,Mechlenburg I,Soballe K,Roemer L,Stilling M

    更新日期:2018-12-17 00:00:00

  • Articular cartilage regeneration using acellular bioactive affinity-binding alginate hydrogel: A 6-month study in a mini-pig model of osteochondral defects.

    abstract:Background:Despite intensive research, regeneration of articular cartilage largely remains an unresolved medical concern as the clinically available modalities still suffer from long-term inconsistent data, relatively high failure rates and high prices of more promising approaches, such as cell therapy. In the present ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2018.08.003

    authors: Ruvinov E,Tavor Re'em T,Witte F,Cohen S

    更新日期:2018-09-09 00:00:00

  • The roles of inflammatory mediators and immunocytes in tendinopathy.

    abstract::Tendinopathy is a common disease of the musculoskeletal system, particularly in athletes and sports amateurs. In this review, we will present evidence for the critical role of inflammatory mediators and immunocytes in the pathogenesis of tendinopathy and the efficacy of current antiinflammatory therapy and regenerativ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2018.03.003

    authors: Tang C,Chen Y,Huang J,Zhao K,Chen X,Yin Z,Heng BC,Chen W,Shen W

    更新日期:2018-04-14 00:00:00

  • Update on biomaterials for prevention of epidural adhesion after lumbar laminectomy.

    abstract::Lumbar laminectomy often results in failed back surgery syndrome. Most scholars support the three-dimensional theory of adhesion: Fibrosis surrounding the epidural tissues is based on the injured sacrospinalis behind, fibrous rings and posterior longitudinal ligaments. Approaches including using the minimally invasive...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2018.02.001

    authors: Wang H,Sun W,Fu D,Shen Y,Chen YY,Wang LL

    更新日期:2018-03-07 00:00:00

  • Corrigendum to 'Regenerative technologies to bed side: Evolving the regulatory' [J Orthop Translat 9 (2017) 1-7].

    abstract::[This corrects the article DOI: 10.1016/j.jot.2017.02.001.]. ...

    journal_title:Journal of orthopaedic translation

    pub_type: 已发布勘误

    doi:10.1016/j.jot.2017.12.005

    authors: Sakai D,Schol J,Foldager CB,Sato M,Watanabe M

    更新日期:2018-02-03 00:00:00

  • Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis.

    abstract:Objectives:Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles. At the cellular and molecular level, osteoarthritis (OA) is characterised by alterat...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2017.12.004

    authors: Wang C,Silverman RM,Shen J,O'Keefe RJ

    更新日期:2018-01-02 00:00:00

  • Macrophages and bone inflammation.

    abstract::Bone metabolism is tightly regulated by the immune system. Accelerated bone destruction is observed in many bone diseases, such as rheumatoid arthritis, fracture, and particle-induced osteolysis. These pathological conditions are associated with inflammatory responses, suggesting the contribution of inflammation to bo...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2017.05.002

    authors: Gu Q,Yang H,Shi Q

    更新日期:2017-05-23 00:00:00

  • Pulsed electromagnetic field applications: A corporate perspective.

    abstract::Corporate establishment of US Food & Drug Administration approved pulsed electromagnetic fields (PEMFs) for clinical applications has been achieved. However, optimization of PEMFs for improvement in efficacy for current indications, in addition to the expansion into new indications, is not trivial. Moving directly int...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2017.02.006

    authors: Waldorff EI,Zhang N,Ryaby JT

    更新日期:2017-03-31 00:00:00

  • Predicting the collapse of the femoral head due to osteonecrosis: From basic methods to application prospects.

    abstract::Collapse of the femoral head is the most significant pathogenic complication arising from osteonecrosis of the femoral head. It is related to the disruption of the maintenance of cartilage and bone, and results in an impaired function of the vascular component. A method for predicting the collapse of the femoral head ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2016.11.002

    authors: Chen L,Hong G,Fang B,Zhou G,Han X,Guan T,He W

    更新日期:2017-01-10 00:00:00

  • In vitro toxicity of local anaesthetics and corticosteroids on supraspinatus tenocyte viability and metabolism.

    abstract:Background/Objective:The purpose of this study was to evaluate supraspinatus tenocyte viability and metabolism in explants exposed to various local anaesthetics and corticosteroids. Our hypothesis was that the tendons exposed to these common injectates would have significantly decreased cell viability and metabolism co...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2016.08.002

    authors: Nuelle CW,Cook CR,Stoker AM,Cook JL,Sherman SL

    更新日期:2016-09-28 00:00:00

  • Translational potential of ginsenoside Rb1 in managing progression of osteoarthritis.

    abstract:Background:Osteoarthritis (OA) is the most common degenerative joint disorder. Inflammatory cytokine plays an important role in OA progression. Previous studies have demonstrated that ginsenoside Rb1 would prevent inflammation and apoptosis in chondrocytes. However, we have not found any animal study reporting that Rb1...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2016.03.001

    authors: Chen Y,Lin S,Sun Y,Pan X,Xiao L,Zou L,Ho KW,Li G

    更新日期:2016-03-31 00:00:00

  • Cartilage imaging of a rabbit knee using dual-energy X-ray microscopy and 1.0 T and 9.4 T magnetic resonance imaging.

    abstract:Background/Objective:Osteoarthritis is a common chronic disease of the joints characterised by the degeneration of articular cartilages and subchondral bone. The most common diagnostic imaging used clinically is X-ray; however, it cannot directly image cartilage. Magnetic resonance imaging (MRI) is well suited for cart...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2015.07.003

    authors: Zhu Y,Manske SL,Boyd SK

    更新日期:2015-08-28 00:00:00

  • The effect of hydrogen gas evolution of magnesium implant on the postimplantation mortality of rats.

    abstract:Background/Objective:Hydrogen gas cavity is formed during in vivo degradation of magnesium implants. In many studies, the gas cavity is mostly punctured out subcutaneously. However, this procedure becomes inapplicable in certain internal surgeries; therefore, the effect of this gas cavity is worth further assessment. ...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2015.08.003

    authors: Noviana D,Paramitha D,Ulum MF,Hermawan H

    更新日期:2015-08-20 00:00:00

  • In vivo three-dimensional magnetic resonance imaging of rat knee osteoarthritis model induced using meniscal transection.

    abstract:Background/Objective:In a rat meniscal tear model of osteoarthritis (OA), a full-thickness cut in the medial meniscus leads to joint instability and progressive development of knee OA. This study evaluated in vivo high-resolution three-dimensional magnetic resonance imaging (3D MRI) in demonstrating the knee joint stru...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章

    doi:10.1016/j.jot.2015.06.002

    authors: Wang YJ,Wang J,Deng M,Liu G,Qin L

    更新日期:2015-06-23 00:00:00

  • Past, present, and future of microcarrier-based tissue engineering.

    abstract::The top issue in tissue engineering is how to obtain more seed cells quickly and to preserve their characteristic morphology during in vitro expansion culture of cells. Microcarriers can help to amplify cell numbers and maintain the appropriate phenotype for tissue repair and restoration of function. In addition, micr...

    journal_title:Journal of orthopaedic translation

    pub_type: 杂志文章,评审

    doi:10.1016/j.jot.2015.02.003

    authors: Li B,Wang X,Wang Y,Gou W,Yuan X,Peng J,Guo Q,Lu S

    更新日期:2015-03-13 00:00:00