解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Although a variety of instruments are available that capture stress experience, the assessment of chronic stress has been hindered by the lack of economical screening instruments. Recently, an English-language version of the Trier Inventory for Chronic Stress (TICS-EN) consisting of 57 items according to a s...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01156-y
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:Social-environmental data obtained from the US Census is an important resource for understanding health disparities, but rarely is the full dataset utilized for analysis. A barrier to incorporating the full data is a lack of solid recommendations for variable selection, with researchers often hand-selecting ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01183-9
更新日期:2020-12-10 00:00:00
abstract:BACKGROUND:Precise predictions of incidence and mortality rates due to breast cancer (BC) are required for planning of public health programs as well as for clinical services. A number of approaches has been established for prediction of mortality using stochastic models. The performance of these models intensely depen...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01187-5
更新日期:2020-12-09 00:00:00
abstract:BACKGROUND:In recent months, multiple efforts have sought to characterize COVID-19 social distancing policy responses. These efforts have used various coding frameworks, but many have relied on coding methodologies that may not adequately describe the gradient in social distancing policies as states "re-open." METHODS...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01174-w
更新日期:2020-12-08 00:00:00
abstract:BACKGROUND:Administrative databases offer vast amounts of data that provide opportunities for cost-effective insights. They simultaneously pose significant challenges to statistical analysis such as the redaction of data because of privacy policies and the provision of data that may not be at the level of detail requir...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01181-x
更新日期:2020-12-07 00:00:00
abstract:BACKGROUND:Predicting survival of recipients after liver transplantation is regarded as one of the most important challenges in contemporary medicine. Hence, improving on current prediction models is of great interest.Nowadays, there is a strong discussion in the medical field about machine learning (ML) and whether it...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01153-1
更新日期:2020-11-16 00:00:00
abstract:BACKGROUND:Growth Mixture Modeling (GMM) is commonly used to group individuals on their development over time, but convergence issues and impossible values are common. This can result in unreliable model estimates. Constraining variance parameters across classes or over time can solve these issues, but can also serious...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01154-0
更新日期:2020-11-12 00:00:00
abstract:BACKGROUND:Systematic reviews often require substantial resources, partially due to the large number of records identified during searching. Although artificial intelligence may not be ready to fully replace human reviewers, it may accelerate and reduce the screening burden. Using DistillerSR (May 2020 release), we eva...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01129-1
更新日期:2020-10-15 00:00:00
abstract:BACKGROUND:Emergency Departments (EDs) are a first point-of-contact for many youth with mental health and suicidality concerns and can serve as an effective recruitment source for randomized controlled trials (RCTs) of mental health interventions. However, recruitment in acute care settings is impeded by several challe...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01117-5
更新日期:2020-09-14 00:00:00
abstract:BACKGROUND:Claims databases are generally considered inadequate for obesity research due to suboptimal capture of body mass index (BMI) measurements. This might not be true for bariatric surgery because of reimbursement requirements and changes in coding systems. We assessed the availability and validity of claims-base...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01106-8
更新日期:2020-09-07 00:00:00
abstract:BACKGROUND:Randomised controlled trials (RCTs) are the gold standard for evidence-based practice. However, RCTs can have limitations. For example, translation of findings into practice can be limited by design features, such as inclusion criteria, not accurately reflecting clinical populations. In addition, it is expen...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01078-9
更新日期:2020-07-25 00:00:00
abstract:BACKGROUND:To accurately predict the response to treatment, we need a stable and effective risk score that can be calculated from patient characteristics. When we evaluate such risks from time-to-event data with right-censoring, Cox's proportional hazards model is the most popular for estimating the linear risk score. ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01063-2
更新日期:2020-07-06 00:00:00
abstract:BACKGROUND:A key component of the implementation process is identifying potential barriers and facilitators that need to be addressed. The Theoretical Domains Framework (TDF) is one of the most commonly used frameworks for this purpose. When applying the TDF, it is critical to understand the context in which behaviours...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01056-1
更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:Clinical practice guidelines have become increasingly widely used to guide quality improvement of clinical practice. Qualitative research may be a useful way to improve the quality and implementation of guidelines. The methodology for qualitative evidence used in guidelines development is worthy of further r...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01041-8
更新日期:2020-06-17 00:00:00
abstract:BACKGROUND:This research aims to explore an identified gap in implementation science methodology, that is, how to assess context in implementation research. Context is among the strongest influences on implementation success but is a construct that is poorly understood and reported within the literature. Consequently, ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01044-5
更新日期:2020-06-15 00:00:00
abstract:BACKGROUND:Cross-cultural research with patient-reported outcomes measures (PROMs) assumes that the PROM in the target language will measure the same construct in the same way as the PROM in the source language. Yet translation methods are rarely used to qualitatively maximise construct equivalence or to describe the i...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00962-8
更新日期:2020-05-26 00:00:00
abstract:BACKGROUND:Evidence-based health care is informed by results of randomized clinical trials (RCTs) and their syntheses in meta-analyses. When the trial outcomes measured are not clearly described in trial publications, knowledge synthesis, translation, and decision-making may be impeded. While heterogeneity in outcomes ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01019-6
更新日期:2020-05-25 00:00:00
abstract:BACKGROUND:The COVID-19 pandemic has evolved into one of the most impactful health crises in modern history, compelling researchers to explore innovative ways to efficiently collect public health data in a timely manner. Social media platforms have been explored as a research recruitment tool in other settings; however...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01011-0
更新日期:2020-05-13 00:00:00
abstract:BACKGROUND:While randomised controlled trials (RCTs) provide high-quality evidence to guide practice, much routine care is not based upon available RCTs. This disconnect between evidence and practice is not sufficiently well understood. This case study explores this relationship using a novel approach. Better understan...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-01009-8
更新日期:2020-05-12 00:00:00
abstract:BACKGROUND:Due to limited duration of follow up in clinical trials of cancer treatments, estimates of lifetime survival benefits are typically derived using statistical extrapolation methods. To justify the method used, a range of approaches have been proposed including statistical goodness-of-fit tests and comparing e...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00997-x
更新日期:2020-05-06 00:00:00
abstract:BACKGROUND:Occupational stress and specifically job anxiety are crucial factors in determining health outcomes, job satisfaction as well as performance. In order to assess this phenomenon, the Job Anxiety Scale is one of the instruments available. It consists of 70 items that are clustered in 14 subscales and five dime...
journal_title:BMC medical research methodology
pub_type: 杂志文章,收录出版
doi:10.1186/s12874-020-00974-4
更新日期:2020-04-21 00:00:00
abstract:BACKGROUND:In randomised controlled trials, the assumption of independence of individual observations is fundamental to the design, analysis and interpretation of studies. However, in individually randomised trials in primary care, this assumption may be violated because patients are naturally clustered within primary ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00971-7
更新日期:2020-04-15 00:00:00
abstract:BACKGROUND:Exposure to unhealthy environments and inadequate child stimulation are main risk factors that affect children's health and wellbeing in low- and middle-income countries. Interventions that simultaneously address several risk factors at the household level have great potential to reduce these negative effect...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00950-y
更新日期:2020-04-02 00:00:00
abstract:BACKGROUND:Sero- prevalence studies often have a problem of missing data. Few studies report the proportion of missing data and even fewer describe the methods used to adjust the results for missing data. The objective of this review was to determine the analytical methods used for analysis in HIV surveys with missing ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00944-w
更新日期:2020-03-14 00:00:00
abstract:BACKGROUND:Studies examining incident heart failure (HF) have been limited to select populations. To examine incident HF with broader generalizability, there is need to assemble a HF-free cohort using a geographically-diverse sample. We aimed to develop and validate a simple medication-based strategy for assembling a H...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0890-x
更新日期:2020-03-04 00:00:00
abstract:BACKGROUND:The health regulatory focus is an application of Higgins' regulatory focus theory to a health-specific context. It explains individual differences in health motivation, strategies, and behavior. Previous research found the Health Regulatory Focus Scale (HRFS) to be a reliable and valid measure for the constr...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00927-x
更新日期:2020-03-02 00:00:00
abstract:BACKGROUND:The mechanisms and pathways to impacts from public health research in the UK have not been widely studied. Through the lens of one funder (NIHR), our aims are to map the diversity of public health research, in terms of funding mechanisms, disciplinary contributions, and public health impacts, identify exampl...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-0905-7
更新日期:2020-02-19 00:00:00
abstract:BACKGROUND:This article describes the design and baseline sample of a single-site trial comparing Individual Placement and Support (IPS) supported employment delivered within a Veterans Health Administration (VHA) primary care Patient Aligned Care Team (PACT) to treatment-as-usual vocational rehabilitation (TAU-VR) tha...
journal_title:BMC medical research methodology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12874-020-0919-1
更新日期:2020-02-17 00:00:00
abstract:BACKGROUND:Outcomes in observational studies may not best estimate those expected in the HIV vaccine efficacy trials. We compared retention in Simulated HIV Vaccine Efficacy Trials (SiVETs) and observational cohorts drawn from two key populations in Uganda. METHODS:Two SiVETs were nested within two observational cohor...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-00920-4
更新日期:2020-02-12 00:00:00
abstract:BACKGROUND:Identifying and assessing degree and type of frailty among older persons is a major challenge when targeting high risk populations to identify preventive interventions. The Vulnerable Elders Survey-(VES-13) is a simple instrument to identify frailty defined as risk for death, functional decline or institutio...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-020-0910-x
更新日期:2020-02-05 00:00:00
abstract:BACKGROUND:With the increased empirical interest in the positive significance of improving nurses' sense of professional benefits, there is a requirement for measures of nurses' perceived professional benefit (NPPB). Our objective was to develop and psychometrically test a brief Nurses' Perceived Professional Benefit Q...
journal_title:BMC medical research methodology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12874-020-0908-4
更新日期:2020-01-30 00:00:00
abstract:BACKGROUND:In low-income settings, key outcomes such as biomarkers or clinical assessments are often missing for a substantial proportion of the study population. The aim of this study was to assess the extent to which Heckman-type selection models can create unbiased estimates in such settings. METHODS:We introduce t...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0840-7
更新日期:2019-12-09 00:00:00
abstract:BACKGROUND:To assess cross-cultural validity between Dutch and English versions of the FVQ_CYP, a patient-reported outcome measure developed in the United Kingdom (UK) for children and adolescents with (severe) visual impairment or blindness (VI for brevity) to measure functional vision. METHODS:The 36-item FVQ_CYP wa...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0875-9
更新日期:2019-12-03 00:00:00
abstract:BACKGROUND:Clinical quality registries and other systems that conduct routine post-discharge surveillance of patient outcomes following surgery may have difficulty surveying patients who have limited proficiency in the language of the healthcare provider. Interpreter proxies (family and carers) are often used due to li...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0854-1
更新日期:2019-11-14 00:00:00
abstract:BACKGROUND:Clinical study reports (CSRs) have been increasingly utilised within academic research in recent years. European Medicines Agency (EMA) Policy 0070 'Phase 1,' which came into effect in January 2015, requires the publication of regulatory documents such as CSRs from central applications in an anonymised forma...
journal_title:BMC medical research methodology
pub_type: 杂志文章,评审
doi:10.1186/s12874-019-0836-3
更新日期:2019-11-05 00:00:00
abstract:BACKGROUND:When investigating subgroup effects in meta-analysis, it is unclear whether accounting in meta-regression for between-trial variation in treatment effects, but not between-trial variation in treatment interaction effects when such effects are present, leads to biased estimates, coverage problems, or wrong st...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0831-8
更新日期:2019-10-26 00:00:00
abstract:BACKGROUND:Recruitment to health research remains a major challenge. Innovation is required to meet policy commitments to help patients take part in health research. One innovation that may help meet those policy goals is the development of 'consent to contact' systems, where people give generic consent to be contacted...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0843-4
更新日期:2019-10-22 00:00:00
abstract:BACKGROUND:Dynamic risk models, which incorporate disease-free survival and repeated measurements over time, might yield more accurate predictions of future health status compared to static models. The objective of this study was to develop and apply a dynamic prediction model to estimate the risk of developing type 2 ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0812-y
更新日期:2019-08-14 00:00:00
abstract:BACKGROUND:Participants in voluntary research present a different demographic profile than those who choose not to participate, affecting the generalizability of many studies. Efforts to evaluate these differences have faced challenges, as little information is available from non-participants. Leveraging data from a re...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0809-6
更新日期:2019-08-07 00:00:00
abstract:BACKGROUND:Sleeping under a long-lasting insecticidal net (LLIN) is recommended for all pregnant women in sub-Saharan Africa, due to the high prevalence of malaria infection and its associated complications in the region. Despite this, LLIN use has still remained sub-optimal among pregnant women in Maiduguri, Nigeria. ...
journal_title:BMC medical research methodology
pub_type: 杂志文章
doi:10.1186/s12874-019-0803-z
更新日期:2019-07-18 00:00:00