Development and preliminary validation of a brief nurses' perceived professional benefit questionnaire (NPPBQ).

abstract：BACKGROUND:International clinical trials are now rapidly expanding into Asia. However, the proportion of global trials is higher in South Korea compared to Japan despite implementation of similar governmental support in both countries. The difference in clinical trial environment might influence the respective physicia...

journal_title：BMC medical research methodology

authors： Ito-Ihara T,Hong JH,Kim OJ,Sumi E,Kim SY,Tanaka S,Narita K,Hatta T,Choi EK,Choi KJ,Miyagawa T,Minami M,Murayama T,Yokode M

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:The Behavioral Risk Factor Surveillance System (BRFSS) is a network of health-related telephone surveys--conducted by all 50 states, the District of Columbia, and participating US territories-that receive technical assistance from CDC. Data users often aggregate BRFSS state samples for national estimates wit...

journal_title：BMC medical research methodology

authors： Iachan R,Pierannunzi C,Healey K,Greenlund KJ,Town M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Plasma cell dyscrasias (PCD) are a spectrum of disorders resulting from the clonal expansion of plasma cells, ranging from the pre-malignant condition monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM). MM generates a significant burden of disease on the community and it is pr...

journal_title：BMC medical research methodology

authors： Bergin K,Moore E,McQuilten Z,Wood E,Augustson B,Blacklock H,Ho J,Horvath N,King T,McNeil J,Mollee P,Quach H,Reid CM,Rosengarten B,Walker P,Spencer A

更新日期：2016-11-09 00:00:00

abstract：BACKGROUND:The aim of this study was to examine the relationship between mortality and statin adherence using two different approaches to adherence measurement (summary versus repeated-measures). METHODS:A retrospective cohort study was conducted using administrative data from Saskatchewan, Canada between 1994 and 200...

journal_title：BMC medical research methodology

authors： Alsabbagh MW,Eurich D,Lix LM,Wilson TW,Blackburn DF

更新日期：2017-04-20 00:00:00

abstract：BACKGROUND:Within cancer care, dynamic evaluations of the loss in expectation of life provides useful information to patients as well as physicians. The loss of lifetime function yields the conditional loss in expectation of life given survival up to a specific time point. Due to the inevitable censoring in time-to-eve...

journal_title：BMC medical research methodology

authors： Jakobsen LH,Andersson TM,Biccler JL,El-Galaly TC,Bøgsted M

更新日期：2019-01-28 00:00:00

abstract：BACKGROUND:Data on lifetime exposures are often self-reported in epidemiologic studies, sometimes many years after the relevant age. Validity of self-reported data is usually inferred from their agreement with measured values, but few studies directly quantify the likely effects of reporting errors in body size and rep...

journal_title：BMC medical research methodology

authors： Cairns BJ,Liu B,Clennell S,Cooper R,Reeves GK,Beral V,Kuh D

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:Clinical study reports (CSRs) have been increasingly utilised within academic research in recent years. European Medicines Agency (EMA) Policy 0070 'Phase 1,' which came into effect in January 2015, requires the publication of regulatory documents such as CSRs from central applications in an anonymised forma...

journal_title：BMC medical research methodology

authors： Ferran JM,Nevitt SJ

更新日期：2019-11-05 00:00:00

abstract：BACKGROUND:A recent paper found that terminal digits of statistical values in Nature deviated significantly from an equiprobable distribution, indicating errors or inconsistencies in rounding. This finding, as well as the discovery that a large percentage of p values were inconsistent with reported test statistics, led...

journal_title：BMC medical research methodology

authors： Jeng M

更新日期：2006-09-13 00:00:00

abstract：BACKGROUND:Systematic reviewers seek to comprehensively search for relevant studies and summarize these to present the most valid estimate of intervention effectiveness. The more resources searched, the higher the yield, and thus time and costs required to conduct a systematic review. While there is an abundance of evi...

journal_title：BMC medical research methodology

authors： Crumley ET,Wiebe N,Cramer K,Klassen TP,Hartling L

更新日期：2005-08-10 00:00:00

abstract：BACKGROUND:Growth Mixture Modeling (GMM) is commonly used to group individuals on their development over time, but convergence issues and impossible values are common. This can result in unreliable model estimates. Constraining variance parameters across classes or over time can solve these issues, but can also serious...

journal_title：BMC medical research methodology

authors： Sijbrandij JJ,Hoekstra T,Almansa J,Peeters M,Bültmann U,Reijneveld SA

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:Greater transparency and, in particular, sharing of patient-level data for further scientific research is an increasingly important topic for the pharmaceutical industry and other organisations who sponsor and conduct clinical trials as well as generally in the interests of patients participating in studies....

journal_title：BMC medical research methodology

authors： Tucker K,Branson J,Dilleen M,Hollis S,Loughlin P,Nixon MJ,Williams Z

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:The rationale for commissioning community pulmonary rehabilitation programmes is based on evidence from randomised clinical trials. However, there are a number of reasons why similar programmes might be less effective outside the environment of a clinical trial. These include a less highly selected patient g...

journal_title：BMC medical research methodology

authors： Goyder EC,Strong M,Green A,Holmes MW,Miles G,Reddington O,Lawson R,Lee A,Basran G

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Mediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent by an intervening, mediator variable M. Methods for addressing mediation have been available for ...

journal_title：BMC medical research methodology

authors： Knafl GJ,Knafl KA,Grey M,Dixon J,Deatrick JA,Gallo AM

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:In recent months, multiple efforts have sought to characterize COVID-19 social distancing policy responses. These efforts have used various coding frameworks, but many have relied on coding methodologies that may not adequately describe the gradient in social distancing policies as states "re-open." METHODS...

journal_title：BMC medical research methodology

authors： Lane J,Garrison MM,Kelley J,Sarma P,Katz A

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:Predicting survival of recipients after liver transplantation is regarded as one of the most important challenges in contemporary medicine. Hence, improving on current prediction models is of great interest.Nowadays, there is a strong discussion in the medical field about machine learning (ML) and whether it...

journal_title：BMC medical research methodology

authors： Kantidakis G,Putter H,Lancia C,Boer J,Braat AE,Fiocco M

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Primary-care based randomized controlled trials (RCTs) build an important evidence base for general practice but little evidence exists about barriers to recruitment which often hamper such trials. We investigated the issues that impeded and facilitated recruitment to a clinical trial in general practice. M...

journal_title：BMC medical research methodology

authors： Foster JM,Sawyer SM,Smith L,Reddel HK,Usherwood T

更新日期：2015-03-12 00:00:00

abstract：BACKGROUND:One of the biggest challenges for population health studies is the recruitment of participants. Questions that investigators have asked are "who volunteers for studies?" and "does recruitment method influence characteristics of the samples?" The purpose of this paper was to compare sample characteristics of ...

journal_title：BMC medical research methodology

authors： Leung BM,McDonald SW,Kaplan BJ,Giesbrecht GF,Tough SC

更新日期：2013-12-06 00:00:00

abstract：BACKGROUND:Given an observed test statistic and its degrees of freedom, one may compute the observed P value with most statistical packages. It is unknown to what extent test statistics and P values are congruent in published medical papers. METHODS:We checked the congruence of statistical results reported in all the ...

journal_title：BMC medical research methodology

authors： García-Berthou E,Alcaraz C

更新日期：2004-05-28 00:00:00

abstract：BACKGROUND:Variation in counts between subjects at a given speed or work rate are the most important source of error in physical activity (PA) measurements with accelerometers. The aim of this study was to explore how the use of individual accelerometer cut points (ICPs) affected the analysis of PA field data. METHODS...

journal_title：BMC medical research methodology

authors： Aadland E,Steene-Johannessen J

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:Quantitative Microbial Risk Assessment (QMRA), a modelling approach, is used to assess health risks. Inputs into the QMRA process include data that characterise the intensity, frequency and duration of exposure to risk(s). Data gaps for water exposure assessment include the duration and frequency of urban no...

journal_title：BMC medical research methodology

authors： O'Toole JE,Sinclair MI,Leder K

更新日期：2009-11-09 00:00:00

abstract：BACKGROUND:Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the pop...

journal_title：BMC medical research methodology

authors： Wahlgren L,Schantz P

更新日期：2011-01-17 00:00:00

abstract：BACKGROUND:The "real" effect size of a medical therapy is constant over time. In contrast, the effect size reported in randomised controlled trials (RCTs) may change over time because the sum of all kinds of bias influencing the reported effectiveness is not necessarily constant. As this would affect the validity of me...

journal_title：BMC medical research methodology

authors： Gehr BT,Weiss C,Porzsolt F

更新日期：2006-05-11 00:00:00

abstract：BACKGROUND:Evidence mapping describes the quantity, design and characteristics of research in broad topic areas, in contrast to systematic reviews, which usually address narrowly-focused research questions. The breadth of evidence mapping helps to identify evidence gaps, and may guide future research efforts. The Globa...

journal_title：BMC medical research methodology

authors： Bragge P,Clavisi O,Turner T,Tavender E,Collie A,Gruen RL

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:With the increasing implementation of web-based, mobile health interventions in clinical trials, it is crucial for researchers to address the security and privacy concerns of patient information according to high ethical standards. The full process of meeting these standards is often made more complicated du...

journal_title：BMC medical research methodology

authors： Eagleson R,Altamirano-Diaz L,McInnis A,Welisch E,De Jesus S,Prapavessis H,Rombeek M,Seabrook JA,Park T,Norozi K

更新日期：2017-03-17 00:00:00

abstract：BACKGROUND:Many biological variables sampled from human subjects show a diurnal pattern, which poses special demands on the techniques used to analyze such data. Furthermore, most biological variables belong to nonlinear dynamical systems, which may make linear statistical techniques less suitable to analyze their dyna...

journal_title：BMC medical research methodology

authors： Toonen RB,Wardenaar KJ,Bos EH,van Ockenburg SL,de Jonge P

更新日期：2018-03-21 00:00:00

abstract：BACKGROUND:We developed and validated an automated database case definition for diabetes in children and youth to facilitate pharmacoepidemiologic investigations of medications and the risk of diabetes. METHODS:The present study was part of an in-progress retrospective cohort study of antipsychotics and diabetes in Te...

journal_title：BMC medical research methodology

authors： Bobo WV,Cooper WO,Stein CM,Olfson M,Mounsey J,Daugherty J,Ray WA

更新日期：2012-08-24 00:00:00

abstract：BACKGROUND:Small group research in healthcare is important because it deals with interaction and decision-making processes that can help to identify and improve safer patient treatment and care. However, the number of studies is limited due to time- and resource-intensive data processing. The aim of this study was to e...

journal_title：BMC medical research methodology

authors： Aufegger L,Bicknell C,Soane E,Ashrafian H,Darzi A

更新日期：2019-06-13 00:00:00

abstract：BACKGROUND:E1684 was the pivotal adjuvant melanoma trial for establishment of high-dose interferon (IFN) as effective therapy of high-risk melanoma patients. E1690 was an intriguing effort to corroborate E1684, and the differences between the outcomes of these trials have embroiled the field in controversy over the pas...

journal_title：BMC medical research methodology

authors： Ibrahim JG,Chen MH,Chu H

更新日期：2012-11-29 00:00:00

abstract：BACKGROUND:Diet plays an important role in chronic disease, and the use of dietary pattern analysis has grown rapidly as a way of deconstructing the complexity of nutritional intake and its relation to health. Pattern analysis methods, such as principal component analysis (PCA), have been used to investigate various di...

journal_title：BMC medical research methodology

authors： Zhang F,Tapera TM,Gou J

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:Technical advances following the Human Genome Project revealed that high-quality and -quantity DNA may be obtained from whole saliva samples. However, usability of previously collected samples and the effects of environmental conditions on the samples during collection have not been assessed in detail. In fi...

journal_title：BMC medical research methodology

authors： Nemoda Z,Horvat-Gordon M,Fortunato CK,Beltzer EK,Scholl JL,Granger DA

更新日期：2011-12-19 00:00:00