[Obstacles and facilitators of conducting studies - the perspective of colorectal cancer centers' coordinators].

Abstract:

INTRODUCTION:Clinical trials and health services research are crucial pillars for improving patient care. This paper examines factors inhibiting and promoting the study activity and the knowledge and use of trial registries (e. g. DRKS, StudyBox) as an opportunity to learn about existing studies. MATERIAL AND METHODS:The coordinators of 274 cancer center sites certified according to the requirements of the German Cancer Society were surveyed using a standardized online questionnaire. Data were analyzed using descriptive and bivariate statistics to identify associations with characteristics of the sites (e. g. patient volume, ownership, teaching status). RESULTS:176 sites participated in the survey (64.2 %). The central obstacle to study participa-tion from the centers' view is the low number of existing studies. General knowledge of the population about studies was considered low. Trial registries are known to almost all respondents, but are rarely used. DISCUSSION:The results of the survey suggest that comprehensive measures are needed to sustainably increase the study activity. These include, for example, better information about studies, for example through appropriate databases, and (industry-independent) research funding. One possible way to sensitize patients for studies could be the comprehensive education of the population about the purpose of studies.

journal_name

Z Gastroenterol

authors

Kowalski C,Ferencz J,Benz S,Post S,Seufferlein T,Stinner B,Penzes O,Wesselmann S

doi

10.1055/s-0041-111633

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

409-15

issue

5

eissn

0044-2771

issn

1439-7803

journal_volume

54

pub_type

杂志文章
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  • [Ultrasonic diagnosis of tumors of the cecum and ascending colon].

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    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Grün R,Wagner E,Tomsik H,Sodomann CP,Girona J

    更新日期:1991-02-01 00:00:00

  • [Frequency and pathogenesis of epitheloid cell granuloma in Crohn's disease (author's transl)].

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    doi:

    authors: Schmitz-Moormann P,Malchow H,Miller B,Brandes JW

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  • [Symptoms in patients with adenocarcinoma of the esophagus].

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    doi:10.1055/s-2004-813742

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    更新日期:2005-03-01 00:00:00

  • Measurement of gastric emptying by 13C-octanoic acid breath test versus scintigraphy in diabetics.

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  • [Annular pancreas--a congenital abnormality of the pancreas].

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    doi:

    authors: Bozkurt T,Butsch B,Lederer PC,Lux G

    更新日期:1990-08-01 00:00:00

  • [Cowden syndrome].

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    doi:

    authors: Petritsch W,Pristautz H,Schreiber F,Stauber R,Kullnig P,Höfler H,Smolle J

    更新日期:1990-07-01 00:00:00

  • [Functional characterization of luminal enterocyte membranes of the small intestine mucosa using isolated brush border membranes].

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    pub_type: 杂志文章

    doi:

    authors: Menge H,Stange G,Murer H

    更新日期:1986-11-01 00:00:00

  • [Autoradiography determination of the GABA(A) receptor density in the brain of rats with portacaval shunt].

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    pub_type: 杂志文章

    doi:

    authors: Rössle M,Deckert J,Mullen KD,Jones DB,Grün M,Gerok W,Jones EA

    更新日期:1990-03-01 00:00:00

  • [EHEC-associated colon stenosis after ulcerous-chronic haemorrhagic colitis and consecutive resulting ileus].

    abstract::We report on the case of a segmentally emphasised, ulcerous chronic haemorrhagic colitis with the development of granulation tissue und scarred fibrosis with consecutive resulting stenosis of the colon. A 49-year-old male patient was infected with enterohaemorrhagic Escherichia coli bacteria during the EHEC-epidemic i...

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  • [Yersinia enterocolitica infection with extraintestinal manifestations: case report and overview].

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    pub_type: 杂志文章,评审

    doi:

    authors: Janowitz P,Wechsler JG,Malfertheiner P,Blanco J,Kern P

    更新日期:1994-03-01 00:00:00

  • [Palliative therapy in cholangio- and gallbladder carcinoma].

    abstract::Non-resectable cholangiocarcinoma and gallbladder carcinoma have a poor prognosis. In addition to the general aspects of "best supportive care", biliary drainage is an important part of the palliative treatment of patients with malignant biliary stenosis. Photodynamic therapy has led to an improved median survival in ...

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    pub_type: 杂志文章

    doi:10.1055/s-2001-18537

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    更新日期:2001-11-01 00:00:00

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    abstract::Various sorbents were tested in-vitro for their ability to support hepatic excretory and detoxification functions, and their in-vivo perfusion with plasma was studied in an animal experiment. Amino acids, particularly phenylalanine and tyrosine, were strongest bound by activated charcoal, while Amberlite XAD-7 removed...

    journal_title:Zeitschrift fur Gastroenterologie

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    doi:

    authors: Horak W,Polterauer P,Renner F,Silberbauer K,Rauhs R,Mühlbacher F,Funovics J

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  • [Medicamentous modification of gastrointestinal motility and secretion].

    abstract::This article gives an overview on possible new pharmacological tools to modify gastrointestinal motility and/or secretion. The characterization of new subclasses of classical neurotransmitter receptors and of peptidergic receptors offer a new approach for the development of new therapeutic agents. Using molecular biol...

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  • [Budesonide foam as a new therapeutic principle in distal ulcerative colitis in comparison with mesalazine enema. An open, controlled, randomized and prospective multicenter pilot study].

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  • [Esomeprazol-induced cutaneous lupus erythematosus].

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  • [Extragastric manifestations of H. pylori infection].

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    doi:

    authors: Klump B,Schneider GA,Fierlbeck G,Hoeft S,Gregor M,Porschen R

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  • Simvastatin added to ursodeoxycholic acid does not enhance disappearance of gallstone fragments after shock wave therapy.

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    doi:

    authors: Sackmann M,Koelbl R,Pauletzki J,Cremer P,Klueppelberg UG,von Ritter C,Sauter G,Holl J,Seidel D,Paumgartner G

    更新日期:1995-10-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Lechner HJ,Anton D

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    pub_type: 杂志文章

    doi:

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  • [Long-term drug treatments to improve prognosis of patients with liver cirrhosis and to prevent complications due to portal hypertension].

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    doi:

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    pub_type: 杂志文章,评审

    doi:

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