Ratio of Alpha 2-Macroglobulin Levels in Cerebrospinal Fluid and Serum: An Expression of Neuroinflammation in Acute Disseminated Encephalomyelitis.

abstract：:Methylphenidate (MPH) effects on global and complex measures of electroencephalography were examined in boys with attention-deficit-hyperactivity disorder between the ages of 9 and 11 years. Electroencephalogram (EEG) data were collected separately from the administration of a continuous performance task and were eval...

journal_title：Pediatric neurology

authors： Lubar JF,White JN Jr,Swartwood MO,Swartwood JN

更新日期：1999-09-01 00:00:00

abstract：:Nerve growth factor (NGF) in cerebrospinal fluid was measured by ELISA in ten children with postinfectious diseases and in five children with diseases suggested to be of autoimmune etiology. Three groups of patients were studied: (1) those with moderately elevated concentrations (50.67 +/- 17.02 pg/mL, mean and SEM), ...

journal_title：Pediatric neurology

authors： Riikonen RS,Söderström S,Korhonen LT,Lindholm DB

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Acute disseminated encephalomyelitis (ADEM) is an immune-mediated, inflammatory acquired demyelinating syndrome predominantly affecting the white matter of the central nervous system. METHODS:We describe a three-year-old boy whose clinical presentation was suspicious for ADEM but whose initial imaging abnor...

journal_title：Pediatric neurology

authors： Abu Libdeh A,Goodkin HP,Ramirez-Montealegre D,Brenton JN

更新日期：2017-03-01 00:00:00

abstract：:We analyzed the clinical manifestations, genetic mutations, treatment responses to L-dopa, and long-term neurologic outcomes in Taiwanese infants with tyrosine hydroxylase deficiency. From 1999 to May 2011, we enrolled six infants who had been diagnosed with tyrosine hydroxylase deficiency by identifying point mutatio...

journal_title：Pediatric neurology

authors： Chi CS,Lee HF,Tsai CR

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Weight loss is one of the most frequent side effects of topiramate treatment. The aim of our study was to investigate the effect of topiramate on body mass index, serum glucose, insulin, cortisol, leptin, and neuropeptide-Y levels and the role of these variables on the pathogenesis of weight loss in prepuber...

journal_title：Pediatric neurology

authors： Ozcelik AA,Serdaroglu A,Bideci A,Arhan E,Soysal Ş,Demir E,Gücüyener K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:It is well known that febrile seizures are commonly occur in children with exanthem subitum. In this study, we compared the clinical features and backgrounds of patients with complex febrile seizures with and without primary human herpesvirus 6B infection. METHODS:Sixty-two patients were enrolled after expe...

journal_title：Pediatric neurology

authors： Miyake M,Kawamura Y,Hattori F,Miura H,Ishihara N,Yoshikawa T

更新日期：2020-08-01 00:00:00

abstract：:The aim of this study is to further clarify ictal electroencephalographic findings of patients with benign partial epilepsy in infancy in order to better understand its neurophysiologic features. The study group consisted of 13 infants with definite benign partial epilepsy in infancy, in whom ictal electroencephalogra...

journal_title：Pediatric neurology

authors： Okumura A,Watanabe K,Negoro T,Hayakawa F,Kato T,Natsume J

更新日期：2007-01-01 00:00:00

abstract：:We report the clinical features and the muscle pathology in 2 patients with congenital muscular dystrophy (CMD) secondary to merosin deficiency and in 2 patients with sarcoglycan (adhalin) deficiency. Electron microscopic examination revealed sarcolemmal defects in non-necrotic muscle fibers in all cases. These pathol...

journal_title：Pediatric neurology

authors： Fadic R,Waclawik AJ,Lewandoski PJ,Lotz BP

更新日期：1997-01-01 00:00:00

abstract：:Acute encephalopathy with biphasic seizures and late reduced diffusion was recently established clinicoradiologically as an encephalopathy syndrome. The outcome of this encephalopathy is characterized by a low mortality rate and high incidence of neurologic sequelae. Although the exact pathogenesis of this encephalopa...

journal_title：Pediatric neurology

authors： Matsuo M,Maeda T,Ono N,Sugihara S,Kobayashi I,Koga D,Hamasaki Y

更新日期：2013-03-01 00:00:00

abstract：:We report on the case of a 6-year-old boy with epilepsy involving febrile seizures and unprovoked generalized tonic clonic seizures. Genetic testing revealed a novel de novo mutation in the SCN1A gene (C>T 4786, R1596C). The epilepsy phenotype is within the spectrum of generalized epilepsy with febrile seizures plus. ...

journal_title：Pediatric neurology

authors： Dlugos DJ,Ferraro TN,Buono RJ

更新日期：2007-10-01 00:00:00

abstract：:As part of the implementation of a population-based registry of children with cerebral palsy, caregiver satisfaction with the process by which diagnosis was originally communicated by a professional was assessed. Satisfaction with various aspects of the diagnosis process was assessed using a five-point Likert scale an...

journal_title：Pediatric neurology

authors： Dagenais L,Hall N,Majnemer A,Birnbaum R,Dumas F,Gosselin J,Koclas L,Shevell MI

更新日期：2006-12-01 00:00:00

abstract：:The object of this study was to investigate the potential association of infections, especially group A hemolytic streptococcal infection, with the abrupt onset/exacerbation of tics or obsessive-compulsive behaviors. A structured clinical interview was used to evaluate 80 consecutive children, 5-17 years of age, with ...

journal_title：Pediatric neurology

authors： Singer HS,Giuliano JD,Zimmerman AM,Walkup JT

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The Hammersmith Infant Neurological Examination is one of several useful tools for early identification of cerebral palsy; however, cut-off scores for cerebral palsy do not consistently distinguish infants with hemiplegia from those typically developing. We hypothesized that use of an asymmetry score, in add...

journal_title：Pediatric neurology

authors： Hay K,Nelin M,Carey H,Chorna O,Moore-Clingenpeel Ma Mas M,Maitre N,NCH Early Developmental Group.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:High dosages of natural adrenocorticotropic hormone are used in many centers in the United States for the treatment of infantile spasms. However, lower dosages of synthetic adrenocorticotropic hormone (tetracosactide) might be equally efficient as high dosages. We analyzed the treatment options for infantile...

journal_title：Pediatric neurology

authors： Riikonen R,Lähdetie J,Kokki H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Although cerebral palsy is reported to have a higher prevalence in low-resource settings, there are few studies describing risk factors for cerebral palsy in these settings. A better understanding of the unique risk factors affecting children with cerebral palsy in low-resource settings could optimize both r...

journal_title：Pediatric neurology

authors： Monokwane B,Johnson A,Gambrah-Sampaney C,Khurana E,Baier J,Baranov E,Westmoreland KD,Mazhani L,Steenhoff AP,Bearden DR

更新日期：2017-12-01 00:00:00

abstract：:An 8-year-old boy was diagnosed with autism, along with development delay, seizures, and hypoplastic corpus callosum. His karyotype was 47, XY, +mar.ish (15) (D15Z1+, SNRPN+, GABRB3+, PML-(de novo?). The supernumerary marker chromosome 15 with euchromatin was monosatellited and monocentric. Although autism, seizures, ...

journal_title：Pediatric neurology

authors： Jovanović-Privrodski JD,Kavecan II,Obrenović MR,Buonadonna LA,Bukvić NM

更新日期：2009-07-01 00:00:00

abstract：:Two brothers with congenital myotonic dystrophy also had cystinuria with large renal stones. This report is the first to document the concurrence of cystinuria and congenital myotonic dystrophy. It is uncertain whether these two conditions are coincidental or share a common pathogenesis. ...

journal_title：Pediatric neurology

authors： Kimura S,Amemiya F,Fukazawa H

更新日期：1987-07-01 00:00:00

abstract：:Mycoplasma pneumoniae is a common cause of respiratory tract infection. Extrapulmonary manifestations of M. pneumoniae infection are also common. The present case is that of a previously healthy 4-year-old boy who displayed a novel simultaneous onset of both acute rhabdomyolysis and transverse myelitis associated with...

journal_title：Pediatric neurology

authors： Weng WC,Peng SS,Wang SB,Chou YT,Lee WT

更新日期：2009-02-01 00:00:00

abstract：:The expression of tumor necrosis factor alpha (TNF alpha) was examined in infants with leukomalacia by means of immunohistochemical methods with an antihuman TNF alpha monoclonal antibody. We studied 23 patients with neonatal leukomalacia, classified as having "focal," "widespread," or "diffuse" disease according to t...

journal_title：Pediatric neurology

authors： Deguchi K,Mizuguchi M,Takashima S

更新日期：1996-01-01 00:00:00

abstract：:The brain structure of 14 infants born with congenital myotonic dystrophy at 2 hospitals was evaluated by cranial ultrasonography, and the findings were correlated with clinical and neuropathologic data. Ventricular dilation was diagnosed in 11 infants (78%). Seven infants died during the neonatal period; all had vent...

journal_title：Pediatric neurology

authors： Garcia-Alix A,Cabañas F,Morales C,Pellicer A,Echevarria J,Paisan L,Quero J

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Autosomal recessive or X-linked inborn errors of intracellular cobalamin metabolism can lead to methylmalonic aciduria and homocystinuria. In neonates, both increased cerebrospinal fluid glycine and cerebrospinal fluid/plasma glycine ratio are biochemical features of nonketotic hyperglycinemia. METHODS:We d...

journal_title：Pediatric neurology

authors： Scalais E,Osterheld E,Weitzel C,De Meirleir L,Mataigne F,Martens G,Shaikh TH,Coughlin CR 2nd,Yu HC,Swanson M,Friederich MW,Scharer G,Helbling D,Wendt-Andrae J,Van Hove JLK

更新日期：2017-06-01 00:00:00

abstract：:Twelve patients with hereditary motor and sensory neuropathy with the absence of large myelinated fibers have been reported. All of these patients had central nervous system involvement. In this report, we describe the first patient with pure motor and sensory neuropathy with the absence of large myelinated fibers wit...

journal_title：Pediatric neurology

authors： Fukuda M,Morimoto T,Suzuki Y,Kida K,Ohnishi A

更新日期：2000-10-01 00:00:00

abstract：:A 16-year-old boy had a gradual onset of post-exercise myalgia with progressive fatigue and dizziness. He had bradycardia (37 beats/minute) with low supine and normal standing norepinephrine levels (56 and 311 pg/mL, respectively). He had absent sympathetically mediated vasoconstrictor responses during Valsalva maneuv...

journal_title：Pediatric neurology

authors： Fischer PR,Sandroni P,Pittock SJ,Porter CB,Lehwald LM,Raj SR

更新日期：2010-10-01 00:00:00

abstract：:Epilepsia partialis continua is defined as a spontaneous regular or irregular clonic muscular twitching affecting a limited part of the body, occurring for a minimum of 1 hour and recurring at intervals of less than 10 seconds. Levamisole is used as an immunomodulating medication in patients with recurrent aphthous ul...

journal_title：Pediatric neurology

authors： Aberastury MN,Silva WH,Vaccarezza MM,Maxit C,Agosta G

更新日期：2011-05-01 00:00:00

abstract：:The objective of this study was to examine the factors associated with the occurrence of behavioral and cognitive abnormalities in children treated with topiramate. A retrospective chart review of patients up to 18 years of age who had been treated with topiramate at a tertiary epilepsy center was performed. Behaviora...

journal_title：Pediatric neurology

authors： Gerber PE,Hamiwka L,Connolly MB,Farrell K

更新日期：2000-03-01 00:00:00

abstract：:We report on a previously healthy 11-year-old boy with unilateral periorbital mild headache and facial nerve palsy, followed during the next 5 months by recurrent unilateral headaches and subsequent extrinsic paresis of the third cranial nerve and paresis of the sixth cranial nerve, each of which improved with steroid...

journal_title：Pediatric neurology

authors： Cerisola A,González G,Scavone C

更新日期：2011-01-01 00:00:00

abstract：:Pseudotumor cerebri is a clinical syndrome characterized by increased intracranial pressure in the absence of an intracranial tumor. It is most frequently diagnosed in obese young women, but it is also reported in children of all age groups, including infants. A variety of medical conditions have been suggested as pos...

journal_title：Pediatric neurology

authors： Keren T,Lahat E

更新日期：1998-08-01 00:00:00

abstract：:Möbius syndrome is a rare congenital disease characterized by the paralysis of the facial nerve, accompanied by impaired ocular abduction. We have performed an extensive mutation analysis on a recently identified positional candidate gene, PLEXIN-D1, for Möbius syndrome 2 mapping to chromosome 3q21-q22. Southern analy...

journal_title：Pediatric neurology

authors： van der Zwaag B,Verzijl HT,Wichers KH,Beltran-Valero de Bernabe D,Brunner HG,van Bokhoven H,Padberg GW

更新日期：2004-08-01 00:00:00

abstract：:Auditory event-related potentials (P300 latency; odd-ball paradigm) were examined in 129 patients with childhood epilepsies and 53 controls. The P300 latency in the patients with epilepsies (373 +/- 39.4 ms) was significantly longer than in controls (356 +/- 38.4), and the prolongation was greatest in the patients wit...

journal_title：Pediatric neurology

authors： Konishi T,Naganuma Y,Hongou K,Murakami M,Yamatani M,Yagi S

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Sleep problems affect 30% to 80% of patients with mild traumatic brain injury. We assessed the prevalence of sleep disorders after mild traumatic brain injury and its correlation with other symptoms. METHODS AND MATERIALS:Individuals with mild traumatic brain injury were assessed at the New York University ...

journal_title：Pediatric neurology

authors： Tkachenko N,Singh K,Hasanaj L,Serrano L,Kothare SV

更新日期：2016-04-01 00:00:00