Hemolytic markers following the transfusion of uncrossmatched, cold-stored, low-titer, group O+ whole blood in civilian trauma patients.

abstract：BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

journal_title：Transfusion

authors： Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) antigen and antibody combination assays have been launched as a cost-effective alternative to nucleic acid testing (NAT) for reducing the antibody-negative window period (WP). Later, a HCV antigen chemiluminescence immunoassay (CLIA) became available. STUDY DESIGN AND METHODS:A panel...

journal_title：Transfusion

authors： Laperche S,Nübling CM,Stramer SL,Brojer E,Grabarczyk P,Yoshizawa H,Kalibatas V,El Elkyabi M,Moftah F,Girault A,van Drimmelen H,Busch MP,Lelie N

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Many transfusion services determine the titer of potentially incompatible plasma-containing products by performing a one-dilution titer at their selected titer threshold. This study compared the results of immediate spin (IS) one-dilution titers determined by three methods with a reference standard method. ...

journal_title：Transfusion

authors： Yazer MH,Dunbar NM,Bub CB,Condict BE,Dunn R,Janoušková M,Kutner J,Landová L,Lejdarová H,Nesvačilová B,Pacasová R,Procházková R,Řehořová L,Raval JS,Ziman A,Bohonĕk M

更新日期：2019-04-01 00:00:00

abstract：:Dextran 40 is the main component of the solution used to wash or dilute thawed cord blood unit (CBU) products for stem cell transplant. Dextran 40 became unavailable in the United States as of April 2014. Like many other cellular therapy laboratories in the United States, we found ourselves with limited dextran 40 inv...

journal_title：Transfusion

authors： Reich-Slotky R,Bachegowda LS,Ancharski M,Mendeleyeva L,Rubinstein P,Rennert H,Shore T,van Besien K,Cushing M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Intravenous immunoglobulin G (IVIG) replacement therapy is used to prevent invasive infections in patients with primary antibody deficiency (PAD). However, few studies have functionally evaluated specific antibodies against encapsulated bacteria that cause invasive infection in patients with PAD. In this stu...

journal_title：Transfusion

authors： Lee S,Kim HW,Kim KH

更新日期：2017-01-01 00:00:00

abstract：:Acquired thrombotic thrombocytopenic purpura (TTP) is a disease characterized by microangiopathic hemolytic anemia and thrombocytopenia, in addition to variable fever and neurologic and renal dysfunction, without an underlying cause. Recent advances in elucidating the pathophysiology of acquired TTP have led to new te...

journal_title：Transfusion

authors： Raval JS,Mazepa MA,Brecher ME,Park YA

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Recent genome-wide association studies in Caucasians suggested that an association exists between the ABO gene locus and soluble levels of P-selectin (sP-selectin). However, it is unclear if the relationship corresponds to the phenotypic expression of ABO groups or is present in different ethnic groups. The ...

journal_title：Transfusion

authors： Chen Y,Zhuo X,Lin Y,Huang W,Xiao J,Zeng J,Jiang L,Chen C,Lin H,Dettke M

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Since their description in the 1970s, anti-Hr(B) (antibody against a high-prevalence Rh antigen) and anti-hr(B) (anti-e-like antibody) are still a subject of debate about representing two aspects of a global immune response or being two independent antibodies. STUDY DESIGN AND METHODS:The aim of this study ...

journal_title：Transfusion

authors： Pham BN,Peyrard T,Tourret S,Beolet M,Many H,Juszczak G,Roussel M,Kappler-Gratias S,Rouger P,Le Pennec PY

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:To minimize the bacterial contamination rate in blood collected from donors, a study was designed to evaluate the suitability of a single-use chlorhexidine-alcohol antiseptic for donor arm preparation at all blood collection venues in Australia. STUDY DESIGN AND METHODS:A prospective study of bacterial load...

journal_title：Transfusion

authors： Wong PY,Colville VL,White V,Walker HM,Morris RA,Microbial Contamination and Infection Control Subcommittee, Australian Red Cross Blood Service.

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:By consensus definition, the red blood cells (RBCs) of patients that react weak to 2+ in the serologic D test are classified as having the serologic weak D phenotype (weak D). The risk of D alloimmunization in patients with weak D is not well studied. This study retrospectively determined the incidence of D ...

journal_title：Transfusion

authors： Yazer MH,Brunker PA,Bakdash S,Tobian AA,Triulzi DJ,Earnest V,Harris S,Delaney M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:In spite of interventions, approximately 1000 per 1,000,000 platelet (PLT) collections are contaminated with bacteria at collection. The current prestorage culture procedure at some blood centers is to inoculate a fixed volume from the collection bag (4-8 mL) regardless of collection volume. The sensitivity ...

journal_title：Transfusion

authors： Tomasulo PA,Wagner SJ

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Early identification of acute traumatic coagulopathy is a key challenge during initial management to determine whether to initiate early hemostatic support. We assessed the performance of prothrombin time (PT) at point-of-care in trauma patients to detect moderate and severe coagulopathy on admission. STUDY...

journal_title：Transfusion

authors： Deras P,Nouri J,Martinez O,Aubry E,Capdevila X,Charbit J

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:In sub-Saharan Africa, the percentage of screened blood is limited to approximately 75 percent for human immunodeficiency virus antibodies (anti-HIV), 50 percent for hepatitis B surface antigen, and 19 percent for hepatitis C virus antibodies (anti-HCV), mainly because of costs. STUDY DESIGN AND METHODS:In ...

journal_title：Transfusion

authors： Owusu-Ofori S,Temple J,Sarkodie F,Anokwa M,Candotti D,Allain JP

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:A storage period of 42 days has been approved by the FDA for RBCs stored in NUTRICEL (AS-3). This study was undertaken to provide data to the FDA about the feasibility of salvaging AS-3 RBCs at the end of their storage period by rejuvenation and freezing, and to evaluate the effect of rejuvenation on indicat...

journal_title：Transfusion

authors： Lockwood WB,Hudgens RW,Szymanski IO,Teno RA,Gray AD

更新日期：2003-11-01 00:00:00

abstract：:During a 22-month period, 78,000 blood donors were screened for human T-lymphotropic virus types I and II (HTLV-I/II) at Belle Bonfils Memorial Blood Center (Denver, Colorado). Positive donors and the living recipients of their previously donated blood components were evaluated for risk factors and symptoms related to...

journal_title：Transfusion

authors： Herr V,Ambruso D,Fairfax M,Neumann A,Swanson P,Lee H

更新日期：1993-03-01 00:00:00

abstract：:An apparent anti-Jka, reacting only in the presence of methyl esters of hydroxybenzoic acid (HBA), was detected in an individual with Jk (a+) red blood cells. The antibody was first detected when a commercial low-ionic-strength-solution preparation containing the preservative methyl paraben (a methyl ester of hydroxyb...

journal_title：Transfusion

authors： Halima D,Garratty G,Bueno R

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:A previous study in our hospitals correlated suboptimal documentation and failure to justify transfusions. In light of implemented blood-conservation strategies, including patient blood management (PBM) and prospective audits (PAs), we performed a follow-up study. STUDY DESIGN AND METHODS:We reviewed prospe...

journal_title：Transfusion

authors： Madrigal E,Prajapati S,Avadhani V,Annen K,Friedman MT

更新日期：2017-02-01 00:00:00

abstract：:The ability of the monocyte monolayer assay (MMA) and the chemiluminescence test (CLT) to predict the clinical significance of alloantibodies associated with hemolytic disease of the newborn (HDN) was assessed by the use of 22 well-characterized antisera--predominantly anti-D--from alloimmunized pregnant women. Sevent...

journal_title：Transfusion

authors： Lucas GF,Hadley AG,Nance SJ,Garratty G

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Hemolytic transfusion reactions (HTRs) due to anti-P1 have rarely been reported. There is only one report (from 1945) of an acute HTR due to anti-P1. CASE REPORT:A 74-year-old woman with anti-P1 was given blood that had been found to be compatible by the use of prewarmed serum and saline-suspended red cells...

journal_title：Transfusion

authors： Arndt PA,Garratty G,Marfoe RA,Zeger GD

更新日期：1998-04-01 00:00:00

abstract：:We observed complement (C) activation during intermittent flow apheresis procedures (Haemonetics model 30) in four subjects, two of whom developed adult respiratory distress syndrome (ARDS). Actual C3 conversion during apheresis was illustrated by the finding of significantly elevated C3d levels (p less than 0.05) and...

journal_title：Transfusion

authors： Boogaerts MA,Roelant C,Goossens W,Verwilghen RL

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:A new automated apheresis system has recently been reported as useful in improving peripheral blood HPC collection in adults. The aim of this study has been to verify the utility of this system (AutoPBSC, COBE BCT) for standard leukapheresis and for LVL in the pediatric setting. STUDY DESIGN AND METHODS:A p...

journal_title：Transfusion

authors： Torrabadella M,Olivé T,Ortega JJ,Massuet L

更新日期：2000-04-01 00:00:00

abstract：:We investigated the possibility that the functional impairment in neutrophil (PMN) chemotaxis which occurs during granulocyte concentrate storage might be due to autotoxicity from the release of neutrophil granule contents during storage. Preliminary experiments confirmed that the exposure of fresh PMNs to the intrace...

journal_title：Transfusion

authors： Lane TA,Lamkin GE

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Most patients with severe aplastic anemia (sAA) respond to immunosuppression, but a significant number relapse or develop clonal abnormalities such as paroxysmal nocturnal hemoglobinuria, myelodysplasia, or leukemia. In principle, patients without matched sibling donors and older patients might benefit from ...

journal_title：Transfusion

authors： Sloand EM,Read EJ,Scheinberg P,Tang Y,More K,Leitman SF,Maciejewski J,Young NS

更新日期：2007-07-01 00:00:00

abstract：:This paper presents recent data from quantitative and thermodynamic investigations on A and B erythrocyte antigens. In regard to weak A phenotypes on the basis of quantitative data, practically no gap is observed from the weakest Aend to the strongest A3. Weak B phenotypes give a similar distribution. However, a more ...

journal_title：Transfusion

authors： Salmon C,Lopez M,Cartron JP,Bouguerra A

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:The expected donor loss from recent implementation of antibody to hepatitis B core antigen (anti-HBc) testing in Canada was uncertain but potentially significant based on US experience. To reduce donor loss from false-reactive tests, repeat-reactive donors without other evidence of infection were eligible to...

journal_title：Transfusion

authors： O'Brien SF,Yi QL,Fan W,Fearon MA,Scalia V,Goldman M

更新日期：2009-02-01 00:00:00

abstract：:Current criteria for a reactive (positive) interpretation on hepatitis C virus (HCV) recombinant immunoblot assay (RIBA) require > or = 1+ reactivity to at least two of the four HCV antigens present in the assay. Given that 5-1-1 is a subcomponent of c100-3, there is concern that donor samples reacting only with these...

journal_title：Transfusion

authors： Busch MP,Tobler L,Quan S,Wilber JC,Johnson P,Polito A,Steane E,Zola A,Bahl C,Nelles M

更新日期：1993-01-01 00:00:00

abstract：:The number of cases of transfusion-associated acquired immune deficiency syndrome (TA-AIDS) that will be seen over the next few years is difficult to estimate, because of the uncertainty about the number of persons infected with the human immunodeficiency virus (HIV) via blood transfusion and about the duration of the...

journal_title：Transfusion

authors： Kalbfleisch JD,Lawless JF

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Transfusion-associated Chagas' disease (TA-CD) is a worldwide problem. Measures adopted to prevent TA-CD include the clinical and serologic screening of blood donors and/or the inactivation of Trypanosoma cruzi present in collected blood, using gentian violet as the trypanocidal agent. This study investigate...

journal_title：Transfusion

authors： Moraes-Souza H,Bordin JO,Bardossy L,MacPherson DW,Blajchman MA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Cefotetan can cause severe immune hemolytic anemia that may persist long after the drug is discontinued. To study the binding of cefotetan to RBCs, patients who received cefotetan were followed and tested for the presence of antibody to cefotetan. STUDY DESIGN AND METHODS:Patients receiving cefotetan were i...

journal_title：Transfusion

authors： Davenport RD,Judd WJ,Dake LR

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The risk of transfusion reactions (TR) and the cost of blood has led to efforts to reduce blood use. We changed our practice to transfuse just one instead of two units of red blood cells (RBC) when hemoglobin ≤8 g/dL due to patient blood management (PBM) recommendations. METHODS AND MATERIALS:We compared RB...

journal_title：Transfusion

authors： Gastecki K,Shanley R,Welbig J,Cohn C,Brunstein CG

更新日期：2019-07-01 00:00:00