Abstract:
:Characterizing the relations between exposures and diseases is the central tenet of epidemiology. Researchers may want to evaluate exposure-disease causation by assessing whether the disease under concern is induced by the various exposures - the so-called "attribution". In this paper, the authors propose a method to attribute diseases to multiple pathways based on the causal-pie model. The method can also be used to evaluate the potential impact of an intervention strategy and to allocate responsibility in tort-law liability issues.
journal_name
Clin Epidemioljournal_title
Clinical epidemiologyauthors
Chen C,Lee WCdoi
10.2147/CLEP.S160205subject
Has Abstractpub_date
2018-04-27 00:00:00pages
489-497issn
1179-1349pii
clep-10-489journal_volume
10pub_type
杂志文章abstract:PURPOSE:The primary objective of this study is to examine the race-specific associations between statin use and overall mortality, as well as cardiovascular and cancer mortality, among blacks and whites in the Southeastern United States (US). Little is known about these associations in blacks. PATIENTS AND METHODS:The...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S53492
更新日期:2013-12-19 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. Since the global spread of MRSA in the 1960s, MRSA strains have evolved with increased pathogenic potential. Notably, some strains are now capable of causing persistent infections not only in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S37071
更新日期:2013-07-04 00:00:00
abstract::Memory diseases are the most important determinant of health care service use and quality of life among older individuals. Adverse effects of medication are common among older people, but this age group is underrepresented in clinical trials. Finnish statutory health care and prescription registers, together with pers...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S46622
更新日期:2013-08-07 00:00:00
abstract::Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2), aims to improve treatment and the long-term outcome of patients with...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S33042
更新日期:2012-01-01 00:00:00
abstract::Background: The Swedish National Patient Registry (NPR) is a nationwide registry that is used extensively for epidemiological research. Using the NPR, we recently found a recurrent pregnancy loss (RPL) incidence of 650/100,000 (0.65%) pregnant women in Sweden. It is of great importance that the quality of the coding i...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S199206
更新日期:2019-05-08 00:00:00
abstract:Background:In 2012, liver cancer ranked as the fifth and eighth most common cancer in men and women, respectively, in urban Shanghai. This study aims to present the trend and projection of age-specific incidence and mortality of liver cancer in Shanghai. Methods:We extracted data of liver cancer incident cases and dea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153951
更新日期:2018-03-09 00:00:00
abstract:PURPOSE:Lifestyle factors may influence observed associations between proton pump inhibitor (PPI) usage and health outcomes. The aim of the study reported here was to examine characteristics and differences in lifestyle among PPI users and nonusers. METHODS:This cross-sectional study utilized data from a 2006 populati...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S49354
更新日期:2013-12-04 00:00:00
abstract:AIM OF DATABASE:The Danish Nonmelanoma Skin Cancer Dermatology Database was established in 2008. The aim of this database was to collect data on nonmelanoma skin cancer (NMSC) treatment and improve its treatment in Denmark. NMSC is the most common malignancy in the western countries and represents a significant challen...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99464
更新日期:2016-10-25 00:00:00
abstract:Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S263646
更新日期:2020-08-19 00:00:00
abstract:BACKGROUND:Severe infection resulting in sepsis is recognized as a leading cause of morbidity and mortality worldwide. The purpose of this study is to use longitudinal, population-based data to report national-level hospital metrics, providing a current assessment of the status of sepsis hospitalizations in Canadian ch...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S72282
更新日期:2014-12-05 00:00:00
abstract:BACKGROUND:To date there has not been any nationwide age-standardized incidence data reported for prostate cancer in Nigeria. We examined and integrated diverse trends in the age-specific incidence of prostate cancer into a comprehensive trend for Nigeria, and examined how best the existing data could generate a countr...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S23536
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:A number of studies have shown poorer survival among cancer patients with comorbidity. Several mechanisms may underlie this finding. In this review we summarize the current literature on the association between patient comorbidity and cancer prognosis. Prognostic factors examined include tumor biology, diagn...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S47150
更新日期:2013-11-01 00:00:00
abstract:Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S218670
更新日期:2019-11-08 00:00:00
abstract:Background:The combination of organized cervical cancer screening and childhood HPV vaccination programs has the potential to eliminate cervical cancer in the future. However, only women participating in both programs gain the full protection, and combined non-attenders remain at high risk of developing cervical cancer...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S203023
更新日期:2019-11-08 00:00:00
abstract:OBJECTIVE:In medicine, many more prediction models have been developed than are implemented or used in clinical practice. These models cannot be recommended for clinical use before external validity is established. Though various models to predict mortality in dialysis patients have been published, very few have been v...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S139748
更新日期:2017-09-05 00:00:00
abstract:BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S139895
更新日期:2017-08-17 00:00:00
abstract:BACKGROUND:The Danish National Registry of Patients (DNRP) is a potentially valuable resource for monitoring national trends in the use of chemotherapy and evaluating the benefits and harms of alternative treatments among colorectal cancer (CRC) patients in Denmark. However, the validity of chemotherapy reporting in th...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S49773
更新日期:2013-08-30 00:00:00
abstract:Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164826
更新日期:2018-08-23 00:00:00
abstract:OBJECTIVE:Invasive bladder cancer (IBC) is a common urological malignancy accounting for 4%-5% of all cancers in Denmark. Our aim was to examine possible changes in short- and long-term survival of patients with IBC during 1998-2009. STUDY DESIGN AND SETTING:Data on all patients (N = 4032) with an incident diagnosis o...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S20615
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Assessment of psychosocial functioning in people with schizophrenia is important. The Global Assessment of Functioning (GAF-F) scale represents a widely applied, easy, and quick tool, but its validity and reliability have been debated. The aim was to investigate whether GAF-F scores are associated with other...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S109036
更新日期:2016-09-02 00:00:00
abstract:BACKGROUND:Comorbidity indices summarize complex medical histories into concise ordinal scales, facilitating stratification and regression in epidemiologic analyses. Low subject prevalence in the highest strata of a comorbidity index often prompts combination of upper categories into a single stratum ('collapsing'). O...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/clep.s5757
更新日期:2009-08-09 00:00:00
abstract:Background:Congenital red blood cell (RBC) disorders, such as hemoglobinopathies, are frequent worldwide but with large geographical variation. Growing migration has increased the number of patients with RBC disorders in formerly low prevalence countries, eg, Denmark. However, accurate prevalences are unknown. Methods...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S250251
更新日期:2020-05-21 00:00:00
abstract::[This corrects the article DOI: 10.2147/CLEP.S249903.]. ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,已发布勘误
doi:10.2147/CLEP.S259005
更新日期:2020-04-29 00:00:00
abstract:Purpose:To report completeness of registered surgeries in the Danish hip arthroscopy registry (DHAR) and proportion of patients completing patient-reported outcome measures (PROMs) prior to surgery and at 1-year follow-up. Patients and Methods:Completeness was determined as the number of surgeries registered in DHAR i...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S264683
更新日期:2020-08-04 00:00:00
abstract:Background:The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aim...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S265404
更新日期:2020-10-09 00:00:00
abstract:Background:Hydroxychloroquine and chloroquine may reduce the risk of cancer as they inhibit autophagy, in particular, in people with connective tissue diseases. Methods:The hazard ratios of cancers, metastases, and death were assessed in adults with connective tissue diseases prescribed hydroxychloroquine/chloroquine ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S143563
更新日期:2017-11-03 00:00:00
abstract:PURPOSE:Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. As there is a lack of epidemiological data for RV gastroenteritis (RVGE) in Saudi Arabia, this hospital-based study was designed to estimate the disease burden of RVGE and assess the prevalent RV types in Saudi childr...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S69502
更新日期:2015-02-11 00:00:00
abstract:BACKGROUND:A number of population-based studies have demonstrated lower cancer survival in elderly patients than among middle-aged or younger patients. Also, data quality in cancer registries has been shown to be associated with age. The objective of this study was to examine the recent age-specific cancer survival tre...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S87699
更新日期:2015-07-29 00:00:00
abstract:Purpose:This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. Materials and methods:We investigated two primary care records databases covering UK National Health Service (Clinical Practice Resear...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164112
更新日期:2018-10-09 00:00:00
abstract:Purpose:To establish the validity of intracerebral hemorrhage (ICH) diagnoses in the Danish Stroke Registry (DSR) and the Danish National Patient Registry (DNPR). Patients and Methods:Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S267583
更新日期:2020-12-01 00:00:00