Abstract：
:Neck dissection (ND) is an essential component of treatment in head and neck squamous cell carcinoma (HNSCC). The extent of ND depends on primary tumor location and T and N stage. Trials have demonstrated improved survival for cN+ status with therapeutic ND as well as for cN0 status with selective ND if the primary has a high incidence of occult metastasis. The accuracy of the procedure is of prognostic relevance. In the prognostic model of the TNM classification, the parameter "N" does not only reflect the number of affected lymph nodes, but also their size and extranodal tumor extension. Due to its better prognosis, a positive human papillomavirus (HPV) status is also incorporated in the present TNM classification. In order to minimize morbidity after ND, one seeks to limit its extent without reducing survival time. To this aim, sentinel node biopsy or surveillance with positron-emission computed tomography (PET-CT) in cN0 necks or after primary radio(chemo)therapy are being investigated.
journal_name
HNOjournal_title
HNOauthors
Vahl JM,Hoffmann TKdoi
10.1007/s00106-018-0601-7subject
Has Abstractpub_date
2019-01-01 00:00:00pages
61-76issue
1eissn
0017-6192issn
1433-0458pii
10.1007/s00106-018-0601-7journal_volume
67pub_type
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