Abstract：
:Neck dissection (ND) is an essential component of treatment in head and neck squamous cell carcinoma (HNSCC). The extent of ND depends on primary tumor location and T and N stage. Trials have demonstrated improved survival for cN+ status with therapeutic ND as well as for cN0 status with selective ND if the primary has a high incidence of occult metastasis. The accuracy of the procedure is of prognostic relevance. In the prognostic model of the TNM classification, the parameter "N" does not only reflect the number of affected lymph nodes, but also their size and extranodal tumor extension. Due to its better prognosis, a positive human papillomavirus (HPV) status is also incorporated in the present TNM classification. In order to minimize morbidity after ND, one seeks to limit its extent without reducing survival time. To this aim, sentinel node biopsy or surveillance with positron-emission computed tomography (PET-CT) in cN0 necks or after primary radio(chemo)therapy are being investigated.
journal_name
HNOjournal_title
HNOauthors
Vahl JM,Hoffmann TKdoi
10.1007/s00106-018-0601-7subject
Has Abstractpub_date
2019-01-01 00:00:00pages
61-76issue
1eissn
0017-6192issn
1433-0458pii
10.1007/s00106-018-0601-7journal_volume
67pub_type
杂志文章相关文献
HNO文献大全abstract：:Measures taken to assure medical quality in hospital departments have focused on external quality control. Public health insurance organizations and the society of hospital holders in Germany have now agreed to carry out activities that aims not only at outcome but also at structural and procedural aspects of medical ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:Tumoral lesions in the head and neck region represent a diagnostic and therapeutic challenge in otorhinolaryngologic routine. High-resolution ultrasound is usually able to guide diagnosis. Nevertheless, a definite differentiation between benign and malignant lesions can only be achieved by tissue biopsy. The various o...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-020-00981-3
更新日期：2021-01-08 00:00:00
abstract：BACKGROUND:In the present study we investigated the culturing of fibroblasts on fibrin glue embedded suture nets, to analyse the possibility of using these components in a suture application technique for the closure of a CSF-fistula. RESULTS:Placement of centrally perforated dura pieces on fibrin glue coated surfaces...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-004-1156-3
更新日期：2005-05-01 00:00:00
abstract：:Even today, a wide variety of techniques are performed in parotid pleomorphic adenoma surgery, ranging from enucleation to total parotidectomy. This study reports the results of our experiences. Among a total of 587 surgically treated parotid lesions at the Homburg/Saar University ENT Department from 1968 through 1991...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:In Germany a hospital stay of 6 days following tonsillectomy is recommended. Our retrospective study aimed to evaluate the incidence of hemorrhage following tonsillectomy with regard to the safety of a shorter hospital stay. PATIENTS AND METHODS:5474 patients of our clinic who underwent tonsillectomy betwee...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060170041
更新日期：2001-09-01 00:00:00
abstract：:Immunoserological assays of patients with sudden deafness and progressive hearing losses have revealed the presence of different antibodies, leading to the assumption that immunological processes may be involved. Recent investigations have demonstrated that these patients have phospholipid antibodies that can cause ve...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060050275
更新日期：1998-06-01 00:00:00
abstract：:Sixty patients suffering from an acute inner ear disease were treated by a combination of acetylsalicylic acid (Micristin), an inhibitor of platelet aggregation, and meclofenoxate (Cerutil), a nootropic drug. The success rate in 26 patients with acute isolated unilateral vestibular disorder was 73% (69% with complete ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
abstract：:An expanding skull fracture with exceptional extension into the frontal sinus, the orbit and the ethmoidal cells is discussed. A 12 year old boy fell down the stairs at the age of 8 years and fractured his left frontal bone with extension to the base of the skull. He was seen because of a swelling of the scalp, an int...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1979-02-01 00:00:00
abstract：:The content of magnesium in tissues, erythrocytes and serum was analysed by atomic absorption spectrometry. A higher concentration of magnesium was found in malignant laryngeal tissue and in lymph nodes of the neck compared to homologous pre-cancerous tissue. In pre-cancerous lesions of the larynx the magnesium concen...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
abstract：:Approximately 25% of the population in industrialized countries suffer from IgE-associated Type-1 allergies. Multiple allergens can be tested simultaneously in one assay by using the protein microarray. Moreover, it is possible to measure more than one analytical parameter (e.g. allergen specific IgEs and IgGs) in one...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-010-2224-5
更新日期：2011-10-01 00:00:00
abstract：:Two patients with squamous cell carcinoma of the middle ear appearing 8 years after a tympanoplasty for cholesteatoma are reported. The tumours presented as a recurrent cholesteatoma and a temporal lobe abscess. The pathogenesis of these tumours is discussed. ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1984-02-01 00:00:00
abstract：BACKGROUND:Spontaneous cerebrospinal fluid otorrhea (SCFO) or rhinorrhea originating from laterobasal defects is uncommon. An immediate closure of the defect is mandatory due to the risk of life-threatening meningitis. The purpose of this paper is to review the literature and to present two additional case reports with...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-001-0588-2
更新日期：2002-05-01 00:00:00
abstract：INTRODUCTION:The therapy of choice in nasoseptal defects is reconstruction with vital respiratory mucosa; in particular, three-layer repair using the bridge-flap technique according to Schultz-Coulon is the most promising. Cases exceeding operative limitations can be treated with silastic buttons. Our aim was to overco...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-009-2072-3
更新日期：2010-04-01 00:00:00
abstract：:Electrical stimulation of the human olfactory mucosa was performed by means of an electrode, which was attached to a rhinoscope. Stimulations of the nasal mucosa did not evoke the sensation of smell, but suppressed smell sensations of presented odorants. When electrical stimulation followed the exposure to an odorant ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1985-07-01 00:00:00
abstract：:The number of persons with hearing disability in most countries is more than 10%. In developing countries of the third world, inflammations are the most important cause of hearing dysfunction, but in more civilized countries, more and more individuals are injured by a noisy environment and by noise that is individuall...
journal_title：HNO
pub_type： 杂志文章,评审
doi：
更新日期：1994-08-01 00:00:00
abstract：BACKGROUND:Chronic hoarseness, globus sensation or mucous obstruction are among a wide range of symptoms possibly related to laryngopharyngeal reflux (LPR). METHOD AND RESULTS:A selective literature research was carried out using PubMed, in which original articles and reviews in German and English were included. Altog...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-011-2441-6
更新日期：2012-03-01 00:00:00
abstract：:Two types of growth can be observed clinically in cholesteatoma: an aggressive and a less aggressive type. In this study monoclonal antibodies to Ki-67 proliferation antigen, epidermal growth-related factor (EGFR) and collagen type IV were used to examine cholesteatoma specimens from 36 patients undergoing tympanomast...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Parathyroid carcinoma is a very rare disease that is accompanied by a poor prognosis. Diagnosis is based on laboratory tests (calcium, parathyroid hormone), sonography, and scintigraphy. Complete surgical resection is the treatment of choice. Adjuvant therapy is controversial. The lack of treatment guidelines and expe...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-020-00986-y
更新日期：2021-01-18 00:00:00
abstract：INTRODUCTION:Hearing aids (HA) provide adequate support for many patients with hearing loss, but not all. Around one third of 10.000 patients provided with hearing aids in the Abbreviated Profile of Hearing Aid Benefit felt no actual benefit when using the hearing aid, although they demonstrated the necessary hearing i...
journal_title：HNO
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00106-015-0018-5
更新日期：2015-06-01 00:00:00
abstract：:Immediate operative reposition of traumatic eardrum perforations has been found to give better morphological results when compared with spontaneous healing. The operative technique and results of healing in 32 patients treated at the ENT Department, University Hospital, Zürich, are discussed. ...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
abstract：:A rare case of an adult with a large retropharyngeal cold abscess arising from a lesion of the upper cervical spine and causing airway obstruction is presented. The incidence, clinical features, and early diagnosis of spondylitis by magnetic resonance tomography, and the management of a retropharyngeal abscess are dis...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Tissue engineering is a promising method for the generation of chondrogenic grafts for reconstructive surgery. In cultured chondrocytes, the dedifferentiation of cells seems unavoidable for multiplication. METHODS:In this study, we investigated the expression of distinct markers during the dedifferentiation...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-005-1322-2
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:It has been suggested that auditory processing disorders (APD) and attention deficit/hyperactivity disorders (ADHD) may be the same entity with slightly differing symptoms. For testing this theory we compared parents' ratings of APD and ADHD behavioural characteristics. METHODS:A retrospective study was car...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-005-1288-0
更新日期：2006-05-01 00:00:00
abstract：:Intraoperative magnetic resonance imaging is a widely accepted method for resection control of glial tumors. Increasingly, it is also used during the resection of skull base tumors. Several studies have independently demonstrated an increase in the extent of resection in these tumors with improved prognosis for the pa...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-016-0240-9
更新日期：2017-01-01 00:00:00
abstract：:The skull base was perforated and extensive wounds occurred in the brain during the passage of a nasogastric tube on a 48 year old woman, under general anaesthetic. The patient was treated by artificial respiration but died on the 14th day. The site of entry was the sphenoid sinus. False passage of the tube was favour...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1983-07-01 00:00:00
abstract：:Although the history of intraoperative neuromonitoring (IONM) dates back to the 19th century, the method did not evolve further than the mere differentiation of nerves until recently. Only the development of continuous IONM (cIONM) has allowed for non-stop analysis of excitation amplitude and latency during surgical p...
journal_title：HNO
pub_type： 杂志文章,评审
doi：10.1007/s00106-020-00824-1
更新日期：2020-08-01 00:00:00
abstract：:ENT symptoms due to disorders of the cervical spine are rarely caused by pathological lesions of the cervical spine that can be demonstrated by radiography, but are mostly caused by functional disorders of the upper cervical spine. They include: globus symptoms and dysphonia; pain syndromes in the head and neck; and o...
journal_title：HNO
pub_type： 杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：:The presence of the internal carotid artery in the middle ear is a rare but known vascular anomaly. A blue-reddish mass behind the tympanic membrane, hearing loss and a tinnitus that is synchronous with the pulse are the typical symptoms and should lead to a correct diagnosis. The diagnostic procedure includes high re...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s001060050480
更新日期：1999-11-01 00:00:00
abstract：BACKGROUND:Quality of life is extraordinary affected by malignant tumors of the head and neck region as functions of social interaction are disturbed. MATERIALS AND METHODS:The influence of surgical treatment and postoperative radio(chemo)therapy (RCT) on the quality of life was studied in patients with head and neck ...
journal_title：HNO
pub_type： 杂志文章
doi：10.1007/s00106-012-2628-5
更新日期：2012-12-01 00:00:00
abstract：:Failed intubation in three patients is reported. All three patients suffered sudden, extreme impaired of mask-ventilation. Twice a coniotomy with subsequent tracheostomy proved to be life saving and without permanent injury. In the other patient tracheostomy had been attempted without success, and subsequent, successf...
journal_title：HNO
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
