Abstract:
PURPOSE:The measurement and estimation of diabetes in populations guides resource allocation, health priorities, and can influence practice and future research. To provide a critical reflection on current diabetes surveillance, we provide in-depth discussion about how upstream determinants, prevalence, incidence, and downstream impacts of diabetes are measured in the USA, and the challenges in obtaining valid, accurate, and precise estimates. FINDINGS:Current estimates of the burden of diabetes risk are obtained through national surveys, health systems data, registries, and administrative data. Several methodological nuances influence accurate estimates of the population-level burden of diabetes, including biases in selection and response rates, representation of population subgroups, accuracy of reporting of diabetes status, variation in biochemical testing, and definitions of diabetes used by investigators. Technological innovations and analytical approaches (e.g., data linkage to outcomes data like the National Death Index) may help address some, but not all, of these concerns, and additional methodological advances and validation are still needed. Current surveillance efforts are imperfect, but measures consistently collected and analyzed over several decades enable useful comparisons over time. In addition, we proposed that focused subsampling, use of technology, data linkages, and innovative sensitivity analyses can substantially advance population-level estimation.
journal_name
Curr Diab Repjournal_title
Current diabetes reportsauthors
Ali MK,Siegel KR,Laxy M,Gregg EWdoi
10.1007/s11892-018-1088-zsubject
Has Abstractpub_date
2018-09-19 00:00:00pages
108issue
11eissn
1534-4827issn
1539-0829pii
10.1007/s11892-018-1088-zjournal_volume
18pub_type
杂志文章,评审abstract::Only 21 % of adolescents with type 1 diabetes (T1D) meet glycemic goals set forth by the American Diabetes Association. Adherence to therapy is a particular concern in this population, and the association between poor adherence and worsening glycemic control indicates that there is a critical need to improve adherence...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-015-0621-6
更新日期:2015-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The global prevalence of obesity has increased rapidly over the last decades, posing a severe threat to human health. Currently, bariatric surgery is the most effective therapy for patients with morbid obesity. It is unknown whether this treatment is also suitable for patients with obesity due to a co...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-020-01327-7
更新日期:2020-07-30 00:00:00
abstract::Diabetic neuropathy is a dying back neurodegenerative disease of the peripheral nervous system where mitochondrial dysfunction has been implicated as an etiological factor. Diabetes (type 1 or type 2) invokes an elevation of intracellular glucose concentration simultaneously with impaired growth factor support by insu...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-015-0671-9
更新日期:2015-11-01 00:00:00
abstract::Cell therapy has enormous potential for the treatment of conditions of unmet medical need. Cell therapy may be applied to diabetes mellitus in the context of beta cell replacement or for the treatment of diabetic complications. A large number of cell types including hematopoietic stem cells, mesenchymal stem cells, um...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-013-0469-6
更新日期:2014-03-01 00:00:00
abstract::Neonatal hypoglycemia is an important consequence for the infant of the mother with diabetes. We have reviewed 24 published papers of various protocols for control of glucose in pregnant diabetic women during labor and delivery including our own published work. A relationship of maternal glucose during labor and neona...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-013-0450-4
更新日期:2014-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy. In the USA, four million women are screened annually for GDM in pregnancy in part to improve pregnancy outcomes but also because diagnosis predicts a high risk of future type 2 diabetes mellitus (T2DM). T...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-017-0835-x
更新日期:2017-02-01 00:00:00
abstract::Attention to meal-related insulin replacement in type 2 diabetes is important as insulin deficiency progresses. The physiology in type 2 and type 1 diabetes differs, and optimal use of basal-bolus therapy in type 2 diabetes requires attention to such issues as the role for oral medications, residual endogenous insulin...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-004-0037-1
更新日期:2004-10-01 00:00:00
abstract::Painful neuropathies are frequently encountered in clinical practice as an early or late complication of several systemic disorders. Among them, diabetes is one of the most important due to its epidemiology and the relevance for regulatory agencies in the assessment of efficacy of new analgesics. However, the presenta...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-014-0538-5
更新日期:2014-10-01 00:00:00
abstract::About 10% of patients with the clinical presentation of type 2 diabetes suffer from an autoimmune form of diabetes associated with a rapid decline of residual beta-cell mass and subsequent development of insulin dependency. In this condition, called latent autoimmune diabetes in adults (LADA), there are clinical and m...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-008-0018-x
更新日期:2008-04-01 00:00:00
abstract:PURPOSE OF REVIEW:We provide an overview of the current knowledge regarding the natural history of human type 1 diabetes (T1D) and the documented associations between virus infections (in particular the enteroviruses) and disease development. We review studies that examine whether T1D-specific risk alleles in genes inv...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-019-1192-8
更新日期:2019-08-10 00:00:00
abstract::The prevalence of diabetes is two- to threefold higher in American Indians in Montana compared with the non-Indian population. High rates of diabetes have also been described in Canadian aboriginal populations closely related to the tribes in Montana. Diabetes in pregnancy has increased among Indian mothers and high-b...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-004-0028-2
更新日期:2004-06-01 00:00:00
abstract::The unbiased approach of genome-wide linkage analysis has shown evidence for linkage of type 2 diabetes mellitus to the chromosome 1q21-25 region in at least eight independent studies. More than 26 candidate genes have already been evaluated, but to date none explain the evidence for linkage in this gene-dense region....
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-007-0025-3
更新日期:2007-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Great strides have recently been made in elucidating the role of genetic sequence variation in diabetes pathogenesis. Increasingly, studies are focusing on other factors that may contribute to the pathogenesis of diabetes, such as epigenetics, a term "traditionally" encompassing changes to the DNA tha...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-018-1091-4
更新日期:2018-10-02 00:00:00
abstract:PURPOSE OF REVIEW:The goal of this review is to provide updates on congenital (neonatal) diabetes from 2011 to present, with an emphasis on publications from 2015 to present. RECENT FINDINGS:There has been continued worldwide progress in uncovering the genetic causes of diabetes presenting within the first year of lif...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-018-1016-2
更新日期:2018-06-13 00:00:00
abstract:PURPOSE OF REVIEW:The increasing prevalence of type 2 diabetes is driving the boundaries of clinical diabetes care outside of the traditional office setting. The purpose of this paper will be to review recent technological advances in the medical management of people with type 2 diabetes, spanning the spectrum of care ...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-019-1278-3
更新日期:2019-12-20 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review was to summarize recent advances in the genomics of type 2 diabetes (T2D) and to highlight current initiatives to advance precision health. RECENT FINDINGS:Generation of multi-omic data to measure each of the "biologic layers," developments in describing genomic function an...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-019-1137-2
更新日期:2019-02-26 00:00:00
abstract::Charcot neuro-osteoarthropathy (CN) is among the most devastating complications of neuropathy and now most commonly occurs in the feet of diabetic patients. Because it is relatively rare and because most patients and practitioners do not expect major bone pathology in the absence of significant pain, CN is often misdi...
journal_title:Current diabetes reports
pub_type: 杂志文章
doi:10.1007/s11892-008-0077-z
更新日期:2008-12-01 00:00:00
abstract::Genes influence susceptibility to type 2 diabetes mellitus (T2DM), and both positional cloning and candidate gene approaches have been used to identify these genes. Linkage analysis has generated evidence for T2DM-predisposing variants on chromosome 20q in studies of Caucasians, Asians, and Africans, and fine-mapping ...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-005-0043-y
更新日期:2005-04-01 00:00:00
abstract::Mobile and smartphone (mHealth) technologies have the potential to improve diabetes care and self-management, but little is known about their effectiveness and how patients, providers, and payers currently interact with them. We conducted a systematic review and found only 20 peer-reviewed articles, published since 20...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-015-0680-8
更新日期:2015-12-01 00:00:00
abstract::Recent estimates suggest that 1 in 12 of the global population suffers from diabetes mellitus. Approximately 40 % of those affected will go on to develop diabetes-related chronic kidney disease or diabetic nephropathy (DN). DN is a major cause of disability and premature death. Existing tests for prognostic purposes a...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-016-0724-8
更新日期:2016-03-01 00:00:00
abstract::Type 1 diabetes mellitus is a chronic disease that results from the autoimmune response against pancreatic insulin producing β cells. Apart of several insulin regimens, since the decade of 80s various immunomodulatory regimens were tested aiming at blocking some steps of the autoimmune process against β cell mass and ...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-012-0309-0
更新日期:2012-10-01 00:00:00
abstract::Pharmacologic doses of glucocorticoids and chronic renal failure are challenging comorbidities and complications for safe and effective dosing of insulin for the management of hospitalized patients with diabetes. Glucocorticoids are used widely in hospitalized patients and will commonly provoke new-onset hyperglycemia...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-012-0339-7
更新日期:2013-02-01 00:00:00
abstract::The incidence of both type 1 and type 2 diabetes is increasing globally, most likely explained by environmental changes, such as changing exposures to foods, viruses, and toxins, and by increasing obesity. While cardiovascular disease (CVD) mortality has been declining recently, this global epidemic of diabetes threat...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-013-0380-1
更新日期:2013-06-01 00:00:00
abstract::The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for obesity. However, the exact molecular mechanisms responsible for the effect of FTO on obesity remain largely unknown. Recent studies from genome-wide associated studies reveal that genetic variants in the FTO gene are associated no...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-014-0486-0
更新日期:2014-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Evidence-based treatments for prediabetes can prevent and delay the development of type 2 diabetes in adults. In this review, we propose a framework for population-based diabetes prevention that links screening and prevention activities across key stakeholders. We also discuss gaps in current practice...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-018-1090-5
更新日期:2018-09-19 00:00:00
abstract:PURPOSE OF REVIEW:Obesity and its associated metabolic diseases have reached epidemic proportions worldwide, reducing life expectancy and quality of life. Several drugs have been tested to treat these diseases but many of them have damaging side effects. Consequently, there is an urgent need to develop more effective t...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-017-0866-3
更新日期:2017-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The Diabetes Prevention Program (DPP) is an evidence-based lifestyle change program for prediabetes that is associated with a 58% reduction in 3-year diabetes incidence, and it has been supported by the American Medical Association and the Centers for Disease Control and Prevention. However, 9 in 10 p...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-018-1034-0
更新日期:2018-08-08 00:00:00
abstract::Long-standing type 1 diabetes (T1D) is associated with an absolute loss of endogenous insulin secretion (circulating C-peptide is undetectable) and a related defect in glucose counter-regulation that is often complicated by hypoglycemia unawareness, markedly increasing the risk for severe hypoglycemia. Both the transp...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-012-0294-3
更新日期:2012-10-01 00:00:00
abstract::Low- and middle-income countries (LMICs) face a rapid change in the nutrition transition toward increases in noncommunicable diseases. Underlying this transition are shifts in the agricultural system and the subsequent growth of the modern retail and food service sectors across all regions and countries, a change in t...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-015-0631-4
更新日期:2015-09-01 00:00:00
abstract::The common form of hereditary hemochromatosis is an autosomal recessive disorder most prevalent in Caucasians that results in excessive iron storage. The clinical manifestations of hemochromatosis are protean. HFE genotype, which determines the degree of iron overload and duration of disease have profound effects on d...
journal_title:Current diabetes reports
pub_type: 杂志文章,评审
doi:10.1007/s11892-014-0488-y
更新日期:2014-01-01 00:00:00