Abstract：
BACKGROUND AND AIMS:Walking is the core physical activity of older persons. The assessment of walking capacity is increasingly important for clinical purposes and clinical research. Differences between assessment tools and protocols for short walks to obtain gait characteristics can be responsible for changes, e.g., in gait speed from 0.1 to 0.2 m/s. The purpose of this study was to generate further knowledge for the harmonization and/or standardization of short walk-test protocols for assessing gait characteristics under supervised conditions. METHODS:For this cross-sectional study, 150 community-dwelling older adults (mean age 80.5 ± 4.5 years) were recruited. Participants performed eight walks differing in the distance (8-versus 4-m), static versus dynamic trials and comparing different test speed instructions (usual versus maximal) on an electronic walkway. RESULTS:A meaningful significant difference in mean usual gait speed was documented comparing the 4-m dynamic and static test protocol (0.12 m/s; p = 0.001). For the same comparison over an 8-m distance (dynamic versus static) and for the comparison between usual gait speed over 4-and 8-m, the differences in gait speed were smaller, but still statistically significant (p = 0.001). CONCLUSIONS:Gait speed was faster, if the test protocol did not include a static start or stop. The differences were greater for a shorter walking distance. This aspect should be considered for the comparison of study results and is particularly relevant for systematic reviews and meta-analyses.
journal_name
Aging Clin Exp Resjournal_title
Aging clinical and experimental researchauthors
Krumpoch S,Lindemann U,Rappl A,Becker C,Sieber CC,Freiberger Edoi
10.1007/s40520-020-01703-zsubject
Has Abstractpub_date
2020-09-15 00:00:00eissn
1594-0667issn
1720-8319pii
10.1007/s40520-020-01703-zpub_type
杂志文章abstract：BACKGROUND AND AIMS:Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs. METHODS:This population-based study, with a cross-sectional design, analysed all geriatric c...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324551
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND AND AIMS:Elderly subjects are characterized by a high prevalence of chronic obstructive pulmonary disease (COPD) and frailty. This study examined the predictive role of frailty on long-term mortality in elderly subjects with and without COPD. METHODS:The study assessed mortality after a 12-year follow-up in...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03351076
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Lumbar spinal stenosis (LSS), osteoarthritis (OA) of the knee, and osteoporosis are major locomotive diseases in the elderly population. The aim of this study was to examine the effectiveness of exercise in these three diseases. METHODS:We reviewed the relevant literature, i.e., systematic reviews ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/BF03324783
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Fragility fracture significantly increases risk of future fracture. The fragility fracture cycle should be disrupted. The secondary fracture prevention is important for the patients with fragility hip fracture. The pharmacotherapy for osteoporosis is important for prevention of new fracture. However, many pa...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1094-7
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:To investigate the feasibility and significance of the clinical application of ultrasound score in assessing the clinical severity of acute cholecystitis in the elderly. METHODS:Pre-surgery ultrasonography was performed on 72 elderly patients with acute cholecystitis who were scheduled for cholecystectomy to...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-014-0236-9
更新日期：2015-02-01 00:00:00
abstract：:Most visual and cognitive functions are affected by aging over the lifespan. In this study, our aim was to investigate the loss in sensitivity to different classes of second-order stimuli-a class of stimuli supposed to be mainly processed in extrastriate cortex-in the aging population. These stimuli will then allow on...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1018-6
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND AND AIMS:Functional brain imaging has shown that bilateral brain reorganization may occur after unilateral cerebral damage. The present study searched for evidence of bilateral motor control changes in gait in patients with chronic unilateral stroke. METHODS:Gait variables (temporal and spatial parameters, ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324759
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Age-related structural alterations in motor units and consequential functional manifestations are asserted to underlie the decline in the ability to finely grade, or control, muscular force in upper extremity musculature of older adults. Functional activities requiring appropriately graded muscular ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324415
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Bone structure, geometry and mineral content represent complex traits with a significant heritable component. However, the specific contributing genes have not been unambiguously identified. The aim of the present cross-sectional study was to analyse an association between heel ultrasound measuremen...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324584
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Statins therapy in the secondary prevention of coronary artery disease (CAD) is associated with a lower risk of adverse cardiovascular events. However, little is known regarding the association of elderly patients with nutritional risk on statin therapy. AIMS:To investigate whether older patients with CAD w...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0881-x
更新日期：2018-09-01 00:00:00
abstract：:The occurrence of a given disease in a population is measured by prevalence and incidence. Prevalence reflects the burden of a given disease in a specific population and is calculated as point prevalence or period prevalence. Incidence denotes the number of new cases of a given disease which occur in a cohort of indiv...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/BF03325157
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Given the progressive demographic ageing of the population and the National Health System reforms affecting care at the bedside, a periodic re-evaluation of in-hospital mortality rates and associated factors is recommended. AIMS:To describe the occurrence of in-hospital mortality among patients admitted to ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,多中心研究
doi：10.1007/s40520-016-0576-8
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:The incidence and costs of acute myocardial infarction (AMI) in Europe represent a substantial problem due to population aging. METHODS:Between 2001 and 2005, Italian hospitalization records were examined to evaluate hospital admissions and costs of AMI in adults aged ≥ 45 and in elderly people ≥ 65 or ≥ 75...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03337744
更新日期：2011-02-01 00:00:00
abstract：AIM:We report 3 cases of spontaneous insufficiency fracture of long bones, to promote awareness of this phenomenon to medical personnel dealing with long-term bedridden patients. METHODS:Cases were analyzed in the light of a literature review. RESULTS:Our patients were all women, who were severely debilitated and had...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324821
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Squamous cell carcinoma (SCC) of the oral tongue is one of the most frequent head and neck cancers. The over-70-year age group is the fastest growing segment of the population. Age, however, is not considered a prognostic factor in oral tongue SCC. This study investigated the clinical and histopatho...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324964
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:Sepsis is more common in the elderly. TNF⍺ is recognized as an important mediator in sepsis and Toll-like receptors (TLRs) play an important role in initiating signaling cascades to produce TNF⍺. Little is known about how innate immunity is altered in healthy human aging that predisposes to sepsis. AIMS AND...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-018-1064-0
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Interprofessional collaborative practice (ICP) is currently recommended for the delivery of high-quality integrated care for older people. Frailty prevention and management are key elements to be tackled on a multi-professional level. AIM:This study aims to develop a consensus-based European multi-professio...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-019-01455-5
更新日期：2020-04-01 00:00:00
abstract：:Antioxidative/oxidative balance is one of the important factors for homeostasis. Antioxidative systems which protect from peroxidative damage are supposed to be under the influence of steroid hormones. The implications of this influence are age and gender as well as tissue dependent alterations in antioxidative enzyme...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.3275/8587
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Muscle weakness and 25-hydroxyvitamin D (25(OH)D) deficiency have been associated with adverse outcomes among older adults. However, little is known about the relationship between clinically relevant muscle weakness and 25(OH)D levels in Ecuador. AIMS:To examine the prevalence of muscle weakness and its ass...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-016-0678-3
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Obesity and lack of physical exercise characterize increasing numbers of people in Western societies, resulting in increasing morbidity and mortality. Regular physical exercise, on the other hand, has been shown to be beneficial. Beneficial effects have also been shown in laboratory rodent studies--...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03327370
更新日期：2003-12-01 00:00:00
abstract：:The aim of the study was to look firstly at the changes that occurred in depressive symptomatology over a 5-year period among originally 75-year-old residents in three Nordic localities: Glostrup in Denmark, Göteborg in Sweden and Jyväskylä in Finland, and secondly, at some selected variables if they predicted depress...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：
更新日期：2002-06-01 00:00:00
abstract：BACKGROUND:Oxidative stress is strongly associated with aging and age-related diseases and plays a crucial role in endothelial dysfunction development. AIM:To better understand the molecular mechanisms of aging and stress response in humans, we examined changes to young and older human endothelial cells over time (72,...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-015-0357-9
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Life-space assessment incorporates all movements in terms of the distance from home, the frequency of movement and the need of assistance for movement. Executive function (EF) is an important higher order cognitive ability that controls and guides people's goal-directed actions. We examined the cross-section...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0762-3
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Gait disorders are common in the elderly populations, and their prevalence increases with age. Abnormal gait has been associated with greater risk for adverse outcomes in older adults, such as immobility and falls, which in turn lead to loss of functional independence and death. AIM:The purpose of this revi...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,评审
doi：10.1007/s40520-015-0420-6
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND AND AIM:Several measurements were taken for frailty classification in geriatric population. "Frailty index" is based on "deficits in health," but it is still not available in Italian version. Thus, the aim of the present work was to validate a version of "frailty index" for the Italian geriatric community. ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-017-0793-9
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Changes in sensory- motor systems that occur with age result in a decrease in postural equilibrium, which has been linked with an increased risk of falling in the elderly. Stepping down backwards from a step perturbs dynamic postural equilibrium, thus offering an opportunity to analyze the biomechan...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324776
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Resistance training holds promise for nursing home residents to prevent further disabilities, falls, and fractures. Free weight as well as machine training may offer an efficient option to improve physical performance, but the feasibility of these training regimes among elderly who require continuous institu...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s40520-017-0830-8
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND AND AIMS:The aim of this study was to develop a Turkish version of the Nottingham Extended Activities of Daily Living Scale (NEADLS) and to assess its reliability and validity. METHODS:Sixty healthy volunteers over 67 years old were included in the study. After translation, the Turkish version of the scale ...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03325144
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Peptydil prolyl cis-trans isomerase (PIN-1), which specifically regulates the conformational changes following phosphorylation of several proteins, targets the inactive hyper-phosphorylated tau on the Thr231-Pro motif and directly restores its biological function. Interestingly, PIN-1 is oxidatively...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/BF03324722
更新日期：2007-10-01 00:00:00
abstract：:The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid prof...
journal_title：Aging clinical and experimental research
pub_type： 杂志文章
doi：10.1007/s40520-014-0218-y
更新日期：2014-12-01 00:00:00
