Abstract:
PURPOSE:To characterize crystalline lens dimensions derived from in-vivo spectral-domain optical coherence tomography (SD-OCT) and identify associations between these parameters, ocular biometry and age. METHODS:In this retrospective study, lens thickness (LT), lens diameter (LD) and lens volume (LV) were measured intraoperatively with SD-OCT in 293 eyes undergoing lens surgery. Correlations among LT, LD, LV, age, axial length (AL) and anterior chamber depth (ACD) were analyzed. Multiple regression analysis was performed to determine whether a combination of biometric data could predict LD and LV. RESULTS:Wide variation was observed in LT (3.6 to 5.7mm), LD (7.5 to 11.9mm) and LV (119.9 to 312.4 mm3) of aging eyes. Correlations among the 3 lens dimensions were statistically significant (LV-LT: r=0.785; P<.001; LV-LD: r=0.696; P<.001; LT-LD: r=0.121; P=.039). With age, the correlation coefficients of LT, LD and LV were 0.526, 0.326 and 0.573 respectively (P<.001). While there was significant correlation of AL with LT (r=-0.137; P=.002) and LD (r=0.268; P<.001), it was not significant with LV (r=0.084; P=.15). Subgroup analysis revealed that 19.8% of the long eyes had LD >1 standard deviation (SD) above and 5.2% had LD <1 SD below the mean LD. CONCLUSION:The dimensions of the aging lens vary considerably, and are most accurately characterized by direct measurement of LT, LD, and LV rather than assumptions based on AL. These findings challenge historically proposed relationships between LD and AL, and represent a normative dataset of contemporary geometric features of the aging lens, possibly aiding in surgical decision making and future developments in lens surgery.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Waring GO 4th,Chang DH,Rocha KM,Gouvea L,Penatti Rdoi
10.1016/j.ajo.2020.12.021subject
Has Abstractpub_date
2020-12-29 00:00:00eissn
0002-9394issn
1879-1891pii
S0002-9394(20)30679-6pub_type
杂志文章abstract::We examined two patients who had sudden decrease in vision after intranasal cocaine or methamphetamine abuse. A 38-year-old woman with a history of systemic arterial hypertension developed a central retinal artery occlusion four hours after intranasal use of cocaine. A 26-year-old woman had blurred vision and intraret...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73979-0
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
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abstract:PURPOSE:To report dry eye patients' functional visual acuity, which was measured after sustained eye opening for 10-20 seconds, as a simulation of visual function of daily acts of gazing, which is defined as looking at an object with involuntary blink suppression. METHODS:Interventional clinical nonrandomized comparat...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
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abstract::Dipivefrin, an epinephrine prodromal drug, was used in conjunction with timolol maleate to evaluate the safety and effectiveness of combined therapy. Seventeen patients who had used timolol maleate for at least six months added dipivefrin (Group 1) and seven patients who had used dipivefrin for at least six months add...
journal_title:American journal of ophthalmology
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abstract::We evaluated carbonic anhydrase inhibitors in a crossover study with a placebo and random allocation of treatment administration. Drugs evaluated included acetazolamide tablets and Sequels, dichlorphenamide, ethoxzolamide, methazolamide, and an ascorbic acid placebo. The best tolerated drug was acetazolamide Sequels. ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1978-04-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1979-07-01 00:00:00
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1979-09-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1975-11-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1989-11-15 00:00:00
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journal_title:American journal of ophthalmology
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1985-09-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2017-07-01 00:00:00
abstract:PURPOSE/METHODS:We observed a clinicopathologic correlation of a case of adenocarcinoma of the retinal pigment epithelium. RESULTS/CONCLUSIONS:The ultrasonographic findings of this tumor demonstrated a collar button profile with high internal reflectivity. The ultrasonographic characteristics in this case reflected th...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1995-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1996-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2006-07-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:2006-06-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type:
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更新日期:2016-11-01 00:00:00
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journal_title:American journal of ophthalmology
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更新日期:2004-02-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2014-07-01 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1986-04-15 00:00:00
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journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2021.01.005
更新日期:2021-01-22 00:00:00
abstract:PURPOSE:To describe a group of patients with dense visual field defects following macular hole surgery. METHODS:Nine (7%) of 125 patients reviewed noted onset of dense visual field defects following uncomplicated vitrectomy with gas-fluid exchange for the treatment of macular hole. Patient records were reviewed to inv...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
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更新日期:1996-09-01 00:00:00
abstract::Fifteen patients with malignant epithelial tumors of the conjunctiva were treated with beta-ray ocular applicators filled with radioactive strontium and yttrium (90Sr/90Y). Histologic examination confirmed the diagnosis. There were ten squamous cell carcinomas, four carcinomas in situ, and one case of epidermidalizati...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:1976-02-01 00:00:00