Bone marrow transplantation retinopathy in the absence of radiation therapy.

Abstract:

PURPOSE:To describe a case of bone marrow transplantation retinopathy in a patient in the absence of prior radiation therapy. METHODS:Case report. RESULTS:Bilateral scotomata developed in a 26-year-old woman because of a retinal microvasculopathy two years after receiving an autologous bone marrow transplantation for acute promyelocytic leukemia. No prior radiation therapy had been given. CONCLUSIONS:Certain combinations of antimetabolites used during induction and transplantation may themselves be toxic to the retinal microvasculature. Patients who undergo bone marrow transplantation would benefit from regular and complete eye examinations, even in the absence of prior radiation therapy.

journal_name

Am J Ophthalmol

authors

Cunningham ET Jr,Irvine AR,Rugo HS

doi

10.1016/s0002-9394(14)72023-9

subject

Has Abstract

pub_date

1996-08-01 00:00:00

pages

268-70

issue

2

eissn

0002-9394

issn

1879-1891

pii

S0002-9394(14)72023-9

journal_volume

122

pub_type

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