Prediction of Epithelial Ovarian Cancer Outcomes With Integration of Genomic Data.

Abstract:

:Some of the patients with epithelial ovarian cancer will not respond to initial therapy. These patients have a poor prognosis. Our aim was to identify patients with a worse prognosis by integrating clinical, pathologic, and genomic data. Using publicly available genomic data and integrating it with clinical data, we significantly improved the prediction of patients with worse surgical outcomes and those who do not respond to initial chemotherapy. We further improved these models with more precise data collection and better understanding of the genetic background of the studied population. Better prediction will lead to better patient classification and opportunities for individualized treatment.

journal_name

Clin Obstet Gynecol

authors

Newtson AM,Devor EJ,Gonzalez Bosquet J

doi

10.1097/GRF.0000000000000493

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

92-108

issue

1

eissn

0009-9201

issn

1532-5520

pii

00003081-202003000-00013

journal_volume

63

pub_type

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