Characterization of a TP53 Somatic Variant of Unknown Function From an Ovarian Cancer Patient Using Organoid Culture and Computational Modeling.

abstract：:Retrospective observational studies have suggested that delivery at or beyond 39 weeks has numerous neonatal benefits including less need for respiratory support, fewer neurodevelopmental delays and lower health care costs. This has lead governmental agencies, and professional organizations to endorse a policy of limi...

journal_title：Clinical obstetrics and gynecology

authors： Hoffman MK,Merriam AA,Ehrenthal DB

更新日期：2014-06-01 00:00:00

abstract：:Women with gestational diabetes mellitus require a continuum of care before, during, and after pregnancy for optimal management of hyperglycemia. Postpartum education and lifestyle modification should begin during pregnancy, and should continue during the postpartum period. Women should receive education on the long-t...

journal_title：Clinical obstetrics and gynecology

authors： Castorino K,Jovanovič L

更新日期：2013-12-01 00:00:00

abstract：:The utility and effectiveness of screening mammography in diagnosing breast cancer at earlier stages and reducing disease-specific mortality remain controversial especially as to when to start and stop routine mammographic screening, and whether mammograms should be performed annually or biennially in average-risk wom...

journal_title：Clinical obstetrics and gynecology

authors： Swain M,Jeudy M,Pearlman MD

更新日期：2016-06-01 00:00:00

abstract：:Shoulder dystocia complicates ∼1% of vaginal births. Although fetal macrosomia and maternal diabetes are risk factors for shoulder dystocia, for the most part its occurrence remains largely unpredictable and unpreventable. ...

journal_title：Clinical obstetrics and gynecology

authors： Ouzounian JG

更新日期：2016-12-01 00:00:00

abstract：:In summary, ultrasound plays an important role in the evaluation of the postterm pregnancy, and its use should be considered in the following situations: 1) estimation of fetal weight in the potentially macrosomic infant before vaginal delivery is attempted; 2) frequent evaluation for oligohydramnios using the amnioti...

journal_title：Clinical obstetrics and gynecology

authors： Rodriguez MH

更新日期：1989-06-01 00:00:00

abstract：:Endometriosis is an enigmatic disease affecting up to 10% of reproductive-aged women causing pain and infertility. Up to 50% of women with endometriosis are infertile, and agreement about treatment options has been difficult to establish. The association between endometriosis and infertility is derived from comparison...

journal_title：Clinical obstetrics and gynecology

authors： Holoch KJ,Lessey BA

更新日期：2010-06-01 00:00:00

abstract：:The adnexal mass in a postmenopausal patient poses an important diagnostic and management dilemma for primary care providers and gynecologists. Postmenopausal women are at a significantly increased risk of gynecologic malignancy; yet even in this population the majority of adnexal masses are benign. Evaluation and man...

journal_title：Clinical obstetrics and gynecology

authors： Rauh-Hain JA,Melamed A,Buskwofie A,Schorge JO

更新日期：2015-03-01 00:00:00

abstract：:Intrauterine growth restriction (IUGR) impairs insulin secretion in humans and in animal models of IUGR. Several underlying mechanisms have been implicated, including decreased expression of molecular regulators of β-cell mass and function, in some cases shown to be due to epigenetic changes initiated by an adverse fe...

journal_title：Clinical obstetrics and gynecology

authors： Gatford KL,Simmons RA

更新日期：2013-09-01 00:00:00

abstract：:This article will review the basic principles of risk management, the role of the risk manager, and the importance of risk management in the patient safety movement as it pertains to obstetrics and gynecology. Several tools that are used by risk managers including risk assessments and root cause analyses will be used ...

journal_title：Clinical obstetrics and gynecology

authors： Klein VR

更新日期：2019-09-01 00:00:00

abstract：:One of the most devastating consequences of cancer treatment in the young female population is ovarian damage, resulting in diminished fertility potential. The extent of damage is related to age, chemotherapeutic regimen, and dose of pelvic radiation received. It is crucial that physicians know the impact each of thes...

journal_title：Clinical obstetrics and gynecology

authors： Meirow D,Biederman H,Anderson RA,Wallace WH

更新日期：2010-12-01 00:00:00

abstract：:Venous thromboembolism is a leading cause for maternal mortality. Because of the increase risk for thromboembolism in pregnancy and the postpartum period, the clinician must be on high alert for the signs and symptoms and use appropriate diagnostics in a timely manner so that prompt anticoagulation therapy can be init...

journal_title：Clinical obstetrics and gynecology

authors： Brown HL,Hiett AK

更新日期：2010-06-01 00:00:00

abstract：:Chronic pelvic is a multifaceted condition that often has both peripheral and central generators of pain. Despite its high prevalence, the evaluation and management of a pelvic pain patient often present many challenges to the practicing gynecologist. As with many other chronic pain conditions, pain severity does not ...

journal_title：Clinical obstetrics and gynecology

authors： Carey ET,Moore K

更新日期：2019-12-01 00:00:00

abstract：:We live in a turbulant period with regard to interpersonal relationships. Individuals place great emphasis on their ability to form good relationships. It is a time of desiring and searching; desiring to be engaged in a rewarding relationship and searching for any principles which might promote such involvement. Obste...

journal_title：Clinical obstetrics and gynecology

authors： Burchell RC

更新日期：1978-03-01 00:00:00

abstract：:Recurrent pregnancy loss affects up to 5% of couples trying to establish a family. Evaluation classically begins after 3 consecutive miscarriages of less than 10 weeks of gestation but may be warranted earlier if a prior miscarriage was found to be euploid, or if there is concomitant infertility and/or advancing mater...

journal_title：Clinical obstetrics and gynecology

authors： Stephenson M,Kutteh W

更新日期：2007-03-01 00:00:00

abstract：:Endometriomas are common in reproductive-aged women, but controversy exists regarding their management. PubMed was searched to identify pertinent studies on outcomes of medical and surgical management of endometrioma, with focus on randomized controlled trials and meta-analyses. Surgical excision is more effective tha...

journal_title：Clinical obstetrics and gynecology

authors： Johnstone EB,Link MH

更新日期：2015-12-01 00:00:00

abstract：:The relationship between the clinical state of the cervix and spontaneous onset of labor has long been known. The cervix can be characterized by evaluating five parameters: effacement, dilatation, firmness, position, and level of the presenting part. The relative associations between successful labor induction and the...

journal_title：Clinical obstetrics and gynecology

authors： Fuentes A,Williams M

更新日期：1995-06-01 00:00:00

abstract：:1. The use of ultrasound may improve perinatal outcome in twin pregnancy. 2. Singleton growth curves for FL, BPD, and AC may be used to assess fetal growth prior to 28 weeks gestation. 3. After 28 weeks gestation, specific twin growth curves should be used. However, increased morbidity may be seen when fetal weight fa...

journal_title：Clinical obstetrics and gynecology

authors： D'Alton ME,Mercer BM

更新日期：1990-03-01 00:00:00

abstract：:Maternal mortality is a complex problem requiring complex responses. Nevertheless, every intervention must operate through one of 3 pathways: preventing pregnancy, preventing complications, or preventing death when obstetric complications occur. We describe interventions following each pathway and assess their evidenc...

journal_title：Clinical obstetrics and gynecology

authors： Fortney JA,Leong M

更新日期：2009-06-01 00:00:00

abstract：:Sexual pain is an underrecognized and poorly treated constellation of disorders that significantly impact affected women and their partners. Recognized as a form of chronic pain, sexual pain disorders are heterogeneous and include dyspareunia (superficial and deep), vaginismus, vulvodynia, vestibulitis, and noncoital ...

journal_title：Clinical obstetrics and gynecology

authors： Boardman LA,Stockdale CK

更新日期：2009-12-01 00:00:00

abstract：:The ideal weight gain or energy intake for an individual woman cannot be determined from research studies. Current guidelines for maternal gain, however, combined with individualized assessment and follow-up, can provide the clinician and the pregnant women with a meaningful target and plan for achieving a healthy wei...

journal_title：Clinical obstetrics and gynecology

authors： Abrams B

更新日期：1994-09-01 00:00:00

abstract：:The American College of Obstetricians and Gynecologists and the American Association of Gynecologic Laparoscopists confirm advantages of conventional minimally invasive surgery over laparotomy for benign gynecological procedures; however, adoption remains low for the general gynecologist. A systematic search for gynec...

journal_title：Clinical obstetrics and gynecology

authors： Payne TN,Pitter MC

更新日期：2011-09-01 00:00:00

abstract：:In summary, accurate identification of fetal growth disorders remains a difficult clinical challenge. Many diagnostic parameters have been devised to diagnose these conditions, however, no single test alone allows a confident antenatal diagnosis of IUGR or macrosomia to be established. Until new criteria or new method...

journal_title：Clinical obstetrics and gynecology

authors： Mintz MC,Landon MB

更新日期：1988-03-01 00:00:00

abstract：:Periventricular-intraventricular hemorrhage is an important problem, resulting in significant mortality and morbidity. Attempts to reduce this complication require an understanding of its pathogenesis. In this chapter a model was proposed, consisting of a series of events resulting in rapid changes of cerebral blood f...

journal_title：Clinical obstetrics and gynecology

authors： Morales WJ

更新日期：1991-06-01 00:00:00

abstract：:Detrusor instability is a urodynamic diagnosis made when the detrusor is shown objectively to contract, spontaneously or on provocation, during the filling phase of a cystometrogram while the patient is attempting to inhibit micturition. It often is responsible for symptoms of urgency, frequency, nocturia, urge incont...

journal_title：Clinical obstetrics and gynecology

authors： Wall LL

更新日期：1990-06-01 00:00:00

abstract：:The use of mesh and graft in pelvic reconstructive surgery has increased over the last decade. As the use of these products increased, the frequency and complexity of mesh-related complications has also increased. Management of complications resulting from mesh placement requires a thoughtful, systematic approach. Alt...

journal_title：Clinical obstetrics and gynecology

authors： Barber MD

更新日期：2013-06-01 00:00:00

abstract：:Data manipulation and information management activities are as central to physicians as writing is to the literary profession. It is not surprising that the computer, as an information tool, has become important and accepted in many aspects of our professional lives. Computer applications can significantly help in dai...

journal_title：Clinical obstetrics and gynecology

authors： Jelovsek FR

更新日期：1989-09-01 00:00:00

abstract：:Preterm premature rupture of the membranes remains difficult to predict accurately. The majority of those suffering preterm premature rupture of the membrane lack risk factors that might lead to preventative treatments. Its management is centered on an evaluation of the risks and benefits of attempted pregnancy prolon...

journal_title：Clinical obstetrics and gynecology

authors： Waters TP,Mercer B

更新日期：2011-06-01 00:00:00

abstract：:Predelivery diagnosis of placenta accreta, increta, and percreta (from here referred to as placenta accreta, unless otherwise noted) has increasingly created opportunities to optimize antenatal management. Despite the increased frequency of placenta accreta today, occurring in as many as 1 in 533 to 1 in 272 deliverie...

journal_title：Clinical obstetrics and gynecology

authors： Haunschild C,Yeaton-Massey A,Lyell DJ

更新日期：2018-12-01 00:00:00

abstract：:The responsibility of the physician for viral infections in pregnancy has changed dramatically in the last 15 years. Genital herpes infections have become much more frequent, and the recognition of these infections in women near term is particularly important. Cytomegaloviruses have been found to be the most commom ca...

journal_title：Clinical obstetrics and gynecology

authors： Sever JL

更新日期：1978-06-01 00:00:00

abstract：:Evidence-based guidelines that have been prepared by many professional organizations aimed at assisting the clinician in the initial evaluation of postmenopausal women who should be considered for bone mineral density evaluation by dual-energy x-ray absorptiometry; history, physical examination, and laboratory testing...

journal_title：Clinical obstetrics and gynecology

authors： Kleerekoper M,Gold DT

更新日期：2008-09-01 00:00:00