当前位置： SCI文献检索 > PSYCHONEUROENDOCRINOLOGY期刊下所有文献 > Social withdrawal and testosterone levels in early adolescent boys.

Social withdrawal and testosterone levels in early adolescent boys.

Abstract：

:Social withdrawal may lead to mental health problems and can have a large impact on a life course, particularly among boys. To support adolescents with social withdrawal, an integrative understanding of the biological bases would be helpful. Social dominance, a possible opposite of social withdrawal, is known to have positive associations with testosterone levels. A previous study suggested that social withdrawal has a negative relationship with sexual maturity among adolescent boys. However, the relationship between social withdrawal and testosterone in adolescence is unknown. This study aimed to examine whether social withdrawal was negatively associated with testosterone levels in early adolescent boys. Salivary samples were collected from 159 healthy early adolescent boys (mean age [standard deviation]: 11.5 [0.73]) selected from participants of the "population-neuroscience study of the Tokyo Teen Cohort" (pn-TTC). Social withdrawal and confounding factors, such as the secondary sexual characteristics and their age in months, were evaluated by self-administered questionnaires completed by the primary parents. The degree of social withdrawal was assessed with the Child Behaviour Checklist (CBCL). Levels of salivary testosterone, and cortisol as a control, were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Logistic regression was conducted to examine the association between social withdrawal and testosterone levels. A higher risk of social withdrawal was associated with a lower salivary testosterone level after adjustment for age in months (odds ratio 0.55, 95 % confidence interval 0.33-0.94), and the association remained significant after adjusting for body mass index, the degree of anxiety/depression and pubertal stage. Thus, we found a negative relationship between social withdrawal and testosterone levels in early adolescent boys. These findings may help to clarify the biological foundations of and to develop support for social withdrawal.

journal_name

Psychoneuroendocrinology

journal_title

Psychoneuroendocrinology

authors

Hayashi N,Ando S,Jinde S,Fujikawa S,Okada N,Toriyama R,Masaoka M,Sugiyama H,Shirakawa T,Yagi T,Morita M,Morishima R,Kiyono T,Yamasaki S,Nishida A,Kasai K

doi

10.1016/j.psyneuen.2020.104596

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

104596

eissn

0306-4530

issn

1873-3360

pii

S0306-4530(20)30015-9

journal_volume

116

pub_type

杂志文章

相关文献

PSYCHONEUROENDOCRINOLOGY文献大全
  • The association of hypothalamic-pituitary-adrenal axis activity and blood pressure in an Afro-Caribbean population.

    abstract：:Hyperactivity of the hypothalamic-pituitary-adrenal axis (HPAA) resulting from fetal programming may play a role in the development of high blood pressure (BP) in black people. We assessed the diurnal salivary cortisol profile in children with and without increased BP and evaluated their mother's HPAA. In a cross-sect...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2008.12.005

    authors： Boyne MS,Woollard A,Phillips DI,Taylor-Bryan C,Bennett FI,Osmond C,Thomas TY,Wilks RJ,Forrester TE

    更新日期：2009-06-01 00:00:00

  • Maternal chronic stress correlates with serum levels of cortisol, glucose and C-peptide in the fetus, and maternal non chronic stress with fetal growth.

    abstract：INTRODUCTION:During pregnancy, maternal stressors cause changes in both maternal and fetal HPA axes. We therefore investigated the impact of maternal non chronic and chronic stress on fetal glucose metabolism and growth, and serum levels of cortisol in the fetus. MATERIALS AND METHODS:Normal weight pregnant women (n =...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.104591

    authors： Valsamakis G,Papatheodorou D,Chalarakis N,Manolikaki M,Margeli A,Papassotiriou I,Barber TM,Kumar S,Kalantaridou S,Mastorakos G

    更新日期：2020-04-01 00:00:00

  • ADP ribosyl-cyclases (CD38/CD157), social skills and friendship.

    abstract：:Why some individuals seek social engagement while others shy away has profound implications for normal and pathological human behavior. Evidence suggests that oxytocin (OT), the paramount human social hormone, and CD38 that governs OT release, contribute to individual differences in social skills from intense social i...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.01.011

    authors： Chong A,Malavasi F,Israel S,Khor CC,Yap VB,Monakhov M,Chew SH,Lai PS,Ebstein RP

    更新日期：2017-04-01 00:00:00

  • Clinical burnout is not reflected in the cortisol awakening response, the day-curve or the response to a low-dose dexamethasone suppression test.

    abstract：:Burnout is presumed to be the result of chronic stress, and chronic stress is known to affect the HPA-axis. To date, studies on HPA-axis functioning in burnout have showed inconsistent results. In the present study, a large sample (n=74) of clinically diagnosed burnout individuals, mostly on sick-leave, were included ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2005.07.003

    authors： Mommersteeg PM,Heijnen CJ,Verbraak MJ,van Doornen LJ

    更新日期：2006-02-01 00:00:00

  • Cerebrospinal fluid and plasma testosterone levels in post-traumatic stress disorder and tobacco dependence.

    abstract：BACKGROUND:Little is known about the relationship between endogenous central nervous system (CNS) testosterone and any psychiatric syndrome. The goal of this study was to screen for potential abnormalities in CNS testosterone levels in patients with post-traumatic stress disorder (PTSD) and/or tobacco dependence. METH...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0306-4530(00)00052-4

    authors： Mulchahey JJ,Ekhator NN,Zhang H,Kasckow JW,Baker DG,Geracioti TD Jr

    更新日期：2001-04-01 00:00:00

  • Small adrenal glands in chronic fatigue syndrome: a preliminary computer tomography study.

    abstract：:No inclusive or satisfactory biomedical explanation for chronic fatigue syndrome (CFS) has as yet been forwarded. Recent research suggests that a dysregulated hypothalamic-pituitary-adrenal axis (HPA) may be contributory, and in particular that there may be diminished forward drive and adrenal under-stimulation. In th...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/s0306-4530(99)00028-1

    authors： Scott LV,Teh J,Reznek R,Martin A,Sohaib A,Dinan TG

    更新日期：1999-10-01 00:00:00

  • Lower allopregnanolone during pregnancy predicts postpartum depression: An exploratory study.

    abstract：:Current evidence is mixed on the role of progesterone and its metabolites in perinatal mood and anxiety disorders. We measured second and third trimester (T2 and T3) progesterone (PROG) and allopregnanolone (ALLO) levels by ELISA and postpartum depression (PPD) by clinician interview (DSM-IV criteria) in 60 pregnant w...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.02.012

    authors： Osborne LM,Gispen F,Sanyal A,Yenokyan G,Meilman S,Payne JL

    更新日期：2017-05-01 00:00:00

  • Chronic systemic administration of serotonergic ligands flibanserin and 8-OH-DPAT enhance HPA axis responses to restraint in female marmosets.

    abstract：BACKGROUND:Flibanserin, a novel serotonin (5-HT)(1A) agonist and 5-HT(2A) antagonist, has been shown to increase sexual desire and reduce distress in women with Hypoactive Sexual Desire Disorder (HSDD). In marmoset monkeys, flibanserin has demonstrated pro-social effects on male-female pairmates, while the classic 5-HT...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2012.05.011

    authors： Aubert Y,Bohl MA,Lange JR,Diol NR,Allers KA,Sommer B,Datson NA,Abbott DH

    更新日期：2013-01-01 00:00:00

  • Cortisol awakening response in healthy children and children with ADHD: impact of comorbid disorders and psychosocial risk factors.

    abstract：:Attention-deficit/hyperactivity disorder (ADHD) is one of the most common child psychiatric disorders. Previous studies have reported a blunted cortisol response to challenging situations and a decreased cortisol awakening response (CAR) in children with ADHD. As ADHD often is comorbid with oppositional defiant disord...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2009.01.018

    authors： Freitag CM,Hänig S,Palmason H,Meyer J,Wüst S,Seitz C

    更新日期：2009-08-01 00:00:00

  • Arginine Vasopressin selectively enhances recognition of sexual cues in male humans.

    abstract：:Arginine Vasopressin modulates complex social and sexual behavior by enhancing social recognition, pair bonding, and aggression in non-human mammals. The influence of Arginine Vasopressin in human social and sexual behavior is, however, yet to be fully understood. We evaluated whether Arginine Vasopressin nasal spray ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.psyneuen.2010.07.023

    authors： Guastella AJ,Kenyon AR,Unkelbach C,Alvares GA,Hickie IB

    更新日期：2011-02-01 00:00:00

  • Effects of differential mating stimulation on the onset of prolactin surges in pseudopregnant rats.

    abstract：:In the female rat, stimulation of the uterine cervix (CS) during mating or by artificial means induces daily diurnal and nocturnal surges in prolactin (PRL) secretion which, in the absence of fertilization, result in an 12-day anestrous period called pseudopregnancy (PSP). The amount or type of mating stimulation rece...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(94)90016-7

    authors： Kornberg E,Erskine MS

    更新日期：1994-01-01 00:00:00

  • Sex hormones and cognitive decline in elderly men.

    abstract：:Decline of cognitive function with age may be due, in part, to hormonal changes and it has been hypothesized that higher levels of endogenous sex hormones preserve brain function. The aim of this prospective cohort study was to determine the relative contribution of endogenous sex hormones to cognitive decline in a po...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2008.08.008

    authors： Muller M,van den Beld AW,Grobbee DE,de Jong FH,Lamberts SW

    更新日期：2009-01-01 00:00:00

  • Grief, depressive symptoms, and inflammation in the spousally bereaved.

    abstract：:Grief is conceptualized by strong negative emotions, which include longing, sadness, and preoccupations with thoughts, recollections, and images of the spouse. In the initial months after the loss of a spouse, those who are widowed are at risk for cardiovascular problems and premature mortality. In the general populat...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.10.006

    authors： Fagundes CP,Brown RL,Chen MA,Murdock KW,Saucedo L,LeRoy A,Wu EL,Garcini LM,Shahane AD,Baameur F,Heijnen C

    更新日期：2019-02-01 00:00:00

  • Pretreatment cortisol predicts trauma-focused psychotherapy response in youth with (partial) posttraumatic stress disorder.

    abstract：BACKGROUND:Despite availability of effective trauma-focused psychotherapies, treatment non-response in youth with (partial) posttraumatic stress disorder remains substantial. Studies in adult PTSD have suggested that cortisol is associated with treatment outcome. Furthermore, cortisol prior to treatment could be used t...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2019.104380

    authors： Zantvoord JB,Ensink JBM,Op den Kelder R,Wessel AMA,Lok A,Lindauer RJL

    更新日期：2019-11-01 00:00:00

  • The role of the amygdala in human fear: automatic detection of threat.

    abstract：:Behavioral data suggest that fear stimuli automatically activate fear and capture attention. This effect is likely to be mediated by a subcortical brain network centered on the amygdala. Consistent with this view, brain imaging studies show that masked facial stimuli activate the amygdala as do masked pictures of thre...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2005.03.019

    authors： Ohman A

    更新日期：2005-11-01 00:00:00

  • Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology.

    abstract：:There is now an expanding volume of evidence to support the view that commensal organisms within the gut play a role in early programming and later responsivity of the stress system. The gut is inhabited by 10¹³-10¹⁴ micro-organisms, which is ten times the number of cells in the human body and contains 150 times as ma...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.psyneuen.2012.03.007

    authors： Dinan TG,Cryan JF

    更新日期：2012-09-01 00:00:00

  • Maternal smoking during pregnancy and infant stress response: test of a prenatal programming hypothesis.

    abstract：BACKGROUND:Maternal smoking during pregnancy (MSDP) is associated with early and long-term neurobehavioral deficits; however mechanisms remain unknown. We tested the hypothesis that MSDP programs the hypothalamic pituitary adrenocortical (HPA) axis of the offspring leading to adverse outcomes. In an intensive, prospect...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2014.05.017

    authors： Stroud LR,Papandonatos GD,Rodriguez D,McCallum M,Salisbury AL,Phipps MG,Lester B,Huestis MA,Niaura R,Padbury JF,Marsit CJ

    更新日期：2014-10-01 00:00:00

  • Pituitary-gonadal function during sleep in healthy aging men.

    abstract：:There is limited information on the relation between age-related changes in pituitary-gonadal function and sleep physiology in older men. In this cross-sectional study of 67 healthy volunteers free from sleep complaints, aged 45-75 yr, we (1) assessed peak fluctuations and hourly variations in plasma testosterone, LH ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(92)90018-3

    authors： Schiavi RC,White D,Mandeli J

    更新日期：1992-11-01 00:00:00

  • Associations of plasma testosterone with clinical manifestations in acute panic disorder.

    abstract：:The probable implication of testosterone in the neurobiology of anxiety disorders, and particularly panic disorder (PD), is poorly studied. We explored for potential differences concerning testosterone (T) plasma levels and the ratio testosterone/cortisol (T/C) between medication-free, consecutively-referred patients ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2018.11.017

    authors： Masdrakis VG,Papageorgiou C,Markianos M

    更新日期：2019-03-01 00:00:00

  • Childhood adversity and cortisol habituation to repeated stress in adulthood.

    abstract：BACKGROUND:Childhood adversity is a robust predictor of poor health outcomes in adulthood and hypothalamic-pituitary-adrenocortical (HPA) axis dysfunction may be a key mechanism explaining this association. However, little is known about the influence childhood adversity may exhibit on adult HPA axis habituation (i.e.,...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2020.105118

    authors： Appelmann HM,Manigault AW,Shorey RC,Zoccola PM

    更新日期：2020-12-24 00:00:00

  • Systemic hormonal and physiological abnormalities in anxiety disorders.

    abstract：:Among the studies of systemic hormonal and physiological abnormalities associated with anxiety disorders, the most consistent and extensive findings suggest (a) peripheral adrenergic hyperactivity (including increases in norepinephrine but not epinephrine) and functional dysregulation, (b) increased incidence of mitra...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/0306-4530(88)90054-6

    authors： Cameron OG,Nesse RM

    更新日期：1988-01-01 00:00:00

  • State associations with the cortisol awakening response in healthy females.

    abstract：:The current study examined intra-individual relationships between the cortisol awakening response (CAR) and state sleep-related and psychosocial variables in a pooled design study. 12 healthy female participants (age range: 22-41 years.) were examined on 12 study days each, occurring at three-day intervals. Quantitati...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2010.02.014

    authors： Stalder T,Evans P,Hucklebridge F,Clow A

    更新日期：2010-09-01 00:00:00

  • Cortisol increase in empathic stress is modulated by emotional closeness and observation modality.

    abstract：:Stress disorders are among the most commonly occurring of all mental disorders. In this context, the question arises whether the stress inevitably unfolding around us has the potential to "contaminate" and compromise us. In the current multi-center study, we investigate the existence of such empathic stress (defined a...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.psyneuen.2014.04.005

    authors： Engert V,Plessow F,Miller R,Kirschbaum C,Singer T

    更新日期：2014-07-01 00:00:00

  • Role of stress in the exacerbation of chronic illness: effects of clonidine administration on blood pressure and plasma norepinephrine, cortisol, growth hormone and prolactin concentrations.

    abstract：:Systolic blood pressure (SBP), diastolic blood pressure (DBP), and plasma norepinephrine (NE), cortisol (CRT), growth hormone (GH) and prolactin (PRL) were studied before and after clonidine (2.5 micrograms/kg i.m.) administration in 193 chronic severely ill patients and 193 normal subjects matched by age and sex. Dur...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/0306-4530(87)90042-4

    authors： Lechin F,van der Dijs B,Jackubowicz D,Camero RE,Lechin S,Villa S,Reinfeld B,Lechin ME

    更新日期：1987-01-01 00:00:00

  • Estradiol levels during the menstrual cycle differentially affect latencies to right and left hemispheres during dichotic listening: an ERP study.

    abstract：:Many behavioral studies have found high-estrogen phases of the menstrual cycle to be associated with enhanced left-hemisphere processing and low-estrogen phases to be associated with better right-hemisphere processing. This study examined the changing of hemispheric asymmetry during the menstrual cycle by analyzing ev...

    journal_title：Psychoneuroendocrinology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.psyneuen.2009.06.018

    authors： Tillman GD

    更新日期：2010-02-01 00:00:00

  • Early adverse experience alters dendritic spine density and gene expression in prefrontal cortex and hippocampus in lambs.

    abstract：:In the laboratory, prenatal stress produces alterations in the structure and function of corticolimbic neurons. Here we report changes in gene expression and corticolimbic dendritic spine morphology in the offspring of pregnant ewes subjected to aversive interactions with human handlers during the last five weeks of p...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2012.10.018

    authors： Coulon M,Wellman CL,Marjara IS,Janczak AM,Zanella AJ

    更新日期：2013-07-01 00:00:00

  • Hippocampal insulin resistance links maternal obesity with impaired neuronal plasticity in adult offspring.

    abstract：OBJECTIVE:Maternal obesity and a disturbed metabolic environment during pregnancy and lactation have been shown to result in many long-term health consequences for the offspring. Among them, impairments in neurocognitive development and performance belong to the most dreaded ones. So far, very few mechanistic approache...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2017.12.023

    authors： Schmitz L,Kuglin R,Bae-Gartz I,Janoschek R,Appel S,Mesaros A,Jakovcevski I,Vohlen C,Handwerk M,Ensenauer R,Dötsch J,Hucklenbruch-Rother E

    更新日期：2018-03-01 00:00:00

  • Depression and cortisol responses to psychological stress: a meta-analysis.

    abstract：:The purpose of this meta-analysis is to examine the association between depression and cortisol responses to psychological stressors. A total of seven studies comparing plasma or cortisol responses to psychological stressors in clinically depressed (MDD) and non-depressed (ND) individuals (N = 196: 98 MDD, 98 ND; 83 m...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.psyneuen.2005.02.010

    authors： Burke HM,Davis MC,Otte C,Mohr DC

    更新日期：2005-10-01 00:00:00

  • Hair cortisol reflects socio-economic factors and hair zinc in preschoolers.

    abstract：:This study examined the relationship between children's hair cortisol and socioeconomic status of the family, as measured by parental education and income. Low family socioeconomic status has traditionally been considered a long-term environmental stressor. Measurement of hair cortisol provides an integrated index of ...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2012.06.009

    authors： Vaghri Z,Guhn M,Weinberg J,Grunau RE,Yu W,Hertzman C

    更新日期：2013-03-01 00:00:00

  • Opioid partial agonist buprenorphine dampens responses to psychosocial stress in humans.

    abstract：:Pre-clinical and clinical evidence indicates that opioid drugs have stress-dampening effects. In animal models, opioid analgesics attenuate responses to isolation distress, and in humans, opioids reduce stress related to anticipation of physical pain. The stress-reducing effects of opioid drugs may contribute to their...

    journal_title：Psychoneuroendocrinology

    pub_type： 杂志文章

    doi：10.1016/j.psyneuen.2014.12.004

    authors： Bershad AK,Jaffe JH,Childs E,de Wit H

    更新日期：2015-02-01 00:00:00