Fertility preservation in breast cancer with case-based examples for guidance.

Abstract:

:With more young breast cancer survivors, a trend toward having children later in life, and improvements in assisted reproductive technology (ART), fertility preserving techniques are of growing importance prior to initiation of gonadotoxic treatments. The American Society for Clinical Oncology (ASCO) updated their Fertility Preservation in Patients with Cancer guidelines in April of 2018. ASCO continues to recognize oocyte and embryo cryopreservation as standard practice for women interested in preserving fertility and sperm cryopreservation as standard practice for men. ASCO has clarified their statement on ovarian suppression during chemotherapy as an option when standard methods are unavailable but should not be used as the sole method of fertility preservation (FP) due to conflicting evidence. ASCO also updated their statement on ovarian tissue cryopreservation, which is still labeled experimental but ASCO acknowledges that it can restore global ovarian function and could be of use in specific patients. The NCCN's Version 1.2018 Clinical Practice Guidelines® for treatment of breast cancer include fertility counseling as part of their work-up in all types of breast cancer for premenopausal women.The purpose of this review is to explain the indications and evidence for the different methods of FP for young breast cancer patients in accordance with ASCO and NCCN guidelines. The guidance will then be applied to three theoretical clinical cases in order to highlight actual use in clinical practice.

journal_name

J Assist Reprod Genet

authors

Hampe ME,Rhoton-Vlasak AS

doi

10.1007/s10815-019-01665-w

subject

Has Abstract

pub_date

2020-03-01 00:00:00

pages

717-729

issue

3

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-019-01665-w

journal_volume

37

pub_type

杂志文章,评审
  • Effect of the site of assisted hatching on vitrified-warmed blastocyst transfer cycles: a prospective randomized study.

    abstract:PURPOSE:To assess the effect of assisted hatching (AH) site on the clinical outcomes in vitrified-warmed blastocyst transfer cycles. METHODS:A total of 160 women who underwent vitrified-warmed blastocyst transfer cycles were randomized to either the ICM group (AH performing at the site near the inner cell mess, ICM), ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10815-013-9984-2

    authors: Ren X,Liu Q,Chen W,Zhu G,Zhang H

    更新日期:2013-06-01 00:00:00

  • Serum progesterone concentration on day of embryo transfer in donor oocyte cycles.

    abstract:PURPOSE:To evaluate the association between serum progesterone (P) levels on the day of embryo transfer (ET) and pregnancy rates in fresh donor IVF/ICSI cycles. METHODS:Fresh donor cycles with day 3 ET from 10/2007 to 8/2012 were included (n = 229). Most cycles (93 %) were programmed with a gonadotropin releasing horm...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-014-0199-y

    authors: Brady PC,Kaser DJ,Ginsburg ES,Ashby RK,Missmer SA,Correia KF,Racowsky C

    更新日期:2014-05-01 00:00:00

  • Oxidative DNA damage impairs global sperm DNA methylation in infertile men.

    abstract:PURPOSE:Methylation of sperm DNA is impaired in many infertile men potentially adversely effecting reproductive outcomes. In somatic cells oxidative damage to DNA and hyperhomocysteinaemia are linked with DNA hypomethylation. The objective of this study was to investigate if these pathologies also impair sperm DNA meth...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-009-9346-2

    authors: Tunc O,Tremellen K

    更新日期:2009-09-01 00:00:00

  • Meta-analysis of the association of AhR Arg554Lys, AhRR Pro185Ala, and ARNT Val189Val polymorphisms and endometriosis risk in Asians.

    abstract:PURPOSE:Several studies have suggested an association between the polymorphisms AhR Arg554Lys, AhRR Pro185Ala, and ARNT Val189Val and endometriosis, but results have been inconclusive. The aim of the present study was to assess these associations by meta-analysis. METHODS:Eligible literatures were retrieved from PubMe...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,meta分析

    doi:10.1007/s10815-015-0505-3

    authors: Zheng NN,Bi YP,Zheng Y,Zheng RH

    更新日期:2015-07-01 00:00:00

  • The effects of cooling mouse oocytes.

    abstract::The effects of cooling and warming on meiotic spindles of mouse oocytes have been assessed by transmission electron microscopy. Intact cumulus-oocyte complexes were immediately cooled from 37 to 15, 4, 0, and -7 degrees C (seeding temperature) for 15 min in a programmed biological freezer and fixed at these temperatur...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF01203754

    authors: Sathananthan AH,Kirby C,Trounson A,Philipatos D,Shaw J

    更新日期:1992-04-01 00:00:00

  • Superovulation with a high gonadotropin dose for in vitro fertilization: is it effective?

    abstract:PURPOSE:Our purpose was to investigate the effect on the ovarian response of increasing the gonadotropin dose. METHODS:We analyzed retrospectively the in vitro fertilization data for patients who had two cycles of treatment, with a higher dose in cycle 2. The patients were stratified according to age, ovarian response...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/BF02744938

    authors: Lashen H,Ledger W,López Bernal A,Evans B,Barlow D

    更新日期:1998-08-01 00:00:00

  • Assessing the impact of delayed blastulation using time lapse morphokinetics and preimplantation genetic testing in an IVF patient population.

    abstract:PURPOSE:There is clinical evidence that early cleavage timing parameters predictive of blastocyst development also correlate with embryo implantation potential. The aim of this study is to determine the developmental competency of embryos with delayed blastulation. METHODS:Retrospective study performed from 2015 to 20...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01501-1

    authors: Kimelman D,Confino R,Okeigwe I,Lambe-Steinmiller J,Confino E,Shulman LP,Zhang JX,Pavone ME

    更新日期:2019-08-01 00:00:00

  • Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience.

    abstract:PURPOSE:To compare the in-vitro fertilization (IVF) outcomes of cancer patients who underwent oocyte retrieval and embryo/oocyte cryopreservation prior to gonadotoxic therapy to those of age and time-matched controls with tubal factor infertility. METHODS:All cancer patients who underwent embryo/oocyte cryopreservatio...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-015-0428-z

    authors: Cardozo ER,Thomson AP,Karmon AE,Dickinson KA,Wright DL,Sabatini ME

    更新日期:2015-04-01 00:00:00

  • Mutational analysis of IZUMO1R in women with fertilization failure and polyspermy after in vitro fertilization.

    abstract:PURPOSE:The etiology of fertilization failure and polyspermy during assisted reproductive technology (ART) remains elusive. The aim of this study was to determine whether mutations in the IZUMO1 receptor (IZUMO1R) gene, which is essential for mammalian fertilization, contribute to the pathogenesis of fertilization fail...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-017-1101-5

    authors: Yu M,Zhao H,Chen T,Tian Y,Li M,Wu K,Bian Y,Su S,Cao Y,Ning Y,Liu H,Chen ZJ

    更新日期:2018-03-01 00:00:00

  • Connections between preimplantation embryo physiology and culture.

    abstract:PURPOSE:To review the history of experimental embryo culture and how culture media that permitted complete preimplantation development in vitro were first discovered, and the physiological insights gained. METHODS:This article reviews the history of in vitro mammalian embryo culture, in particular the efforts that led...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 历史文章,杂志文章,评审

    doi:10.1007/s10815-013-0095-x

    authors: Baltz JM

    更新日期:2013-08-01 00:00:00

  • Does premature luteinization or early surge of LH impair cycle outcome? Report of two successful outcomes.

    abstract:PURPOSE:To report two successful antagonist IVF cycles; one ending up with pregnancy despite premature luteinization (case 1, aged 35 years), and the other with the retrieval of high quality oocytes despite premature ovulation (case 2, aged 39 years). METHODS:Serum LH was 36 and 47 IU/L on cycle day 7 before antagonis...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-009-9299-5

    authors: Sönmezer M,Pelin Cil A,Atabekoğlu C,Ozkavukçu S,Ozmen B

    更新日期:2009-03-01 00:00:00

  • Impact of serum estradiol levels on the implantation rate of cleavage stage cryopreserved-thawed embryos transferred in programmed cycles with exogenous hormonal replacement.

    abstract:PURPOSE:To investigate the impact of late follicular phase serum estradiol (E2) levels on implantation and pregnancy outcomes of cleavage stage cryopreserved/thawed embryos transferred in programmed cycles with exogenous hormonal replacement. METHODS:Retrospective cohort analysis of IVF patients with transfer of cryop...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-014-0402-1

    authors: Bocca S,Real EB,Lynch S,Stadtmauer L,Beydoun H,Mayer J,Oehninger S

    更新日期:2015-03-01 00:00:00

  • Treatment history and outcome of 24 deliveries worldwide after autotransplantation of cryopreserved ovarian tissue, including two new Danish deliveries years after autotransplantation.

    abstract:PURPOSE:To report another two successful pregnancies and deliveries resulting from autotransplanted cryopreserved ovarian tissue several years after the autotransplantation procedure took place. Further, to review the literature on the treatment history, number of live births and their outcome so far reported worldwide...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-014-0331-z

    authors: Macklon KT,Jensen AK,Loft A,Ernst E,Andersen CY

    更新日期:2014-11-01 00:00:00

  • An integrated investigation of oocyte developmental competence: expression of key genes in human cumulus cells, morphokinetics of early divisions, blastulation, and euploidy.

    abstract:PURPOSE:To investigate the association of cumulus cell (CC)-related expression of a selected cluster of key genes (PTGS2, CAMK1D, HAS2, STC1, and EFNB2) with embryo development to blastocyst. METHODS:Exploratory study at a private clinic. Eighteen advanced maternal age patients were enrolled (37.3 ± 4.0 years). Sevent...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01410-3

    authors: Scarica C,Cimadomo D,Dovere L,Giancani A,Stoppa M,Capalbo A,Ubaldi FM,Rienzi L,Canipari R

    更新日期:2019-05-01 00:00:00

  • Fertility preservation in women with cancer: a national study about French oncologists awareness, experience, and feelings.

    abstract:PURPOSE:This study was designed to evaluate patient management and quality of information given by French oncologists to cancer women concerning fertility issues and possibilities of fertility preservation. METHODS:An online survey was sent to 1161 physicians in all major cancer centers throughout France between May 2...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1251-0

    authors: Sallem A,Shore J,Ray-Coquard I,Ferreux L,Bourdon M,Maignien C,Patrat C,Wolf JP,Pocate-Cheriet K

    更新日期:2018-10-01 00:00:00

  • Association study between single-nucleotide variants rs12097821, rs2477686, and rs10842262 and idiopathic male infertility risk in Serbian population with meta-analysis.

    abstract:PURPOSE:A genome-wide association study conducted in the Han Chinese population identified three single nucleotide variants rs12097821, rs2477686, and rs10842262 as being significantly associated with non-obstructive azoospermia. Our aim was to evaluate the possible association between these susceptibility loci and idi...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01920-5

    authors: Nemanja V,Zorana D,Nevena K,Suzana M,Ivan V,Branko B,Mirka D,Dusanka SP,Goran B

    更新日期:2020-11-01 00:00:00

  • Study of two strategies to induce follicular wave emergence for assisted reproductive treatments (ART)-a preliminary trial.

    abstract:PURPOSE:This study aimed to induce follicular wave emergence (FWE) using pharmacological (recombinant hCG administration) or mechanical (aspiration of dominant follicle) interventions in infertile women. METHODS:Sixteen infertile women (≤35 years) with indications for in vitro fertilization due to tubal and/or male fa...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10815-015-0432-3

    authors: Bianchi PH,Viera LM,Gouveia GR,Rocha AM,Baruselli PS,Baracat EC,Serafini PC

    更新日期:2015-04-01 00:00:00

  • "One for Sorrow, Two for Joy?": American embryo transfer guideline recommendations, practices, and outcomes for gestational surrogate patients.

    abstract::In January 2016, Melissa Cook, a California gestational surrogate experiencing a multiple-birth pregnancy following the in vitro fertilization (IVF) transfer of three embryos comprised of donor eggs and sperm provided by the intended father, went to the media when the intended father requested that she undergo a fetal...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-017-0885-7

    authors: White PM

    更新日期:2017-04-01 00:00:00

  • The effect of ease of transfer and type of catheter used on pregnancy and implantation rates in an IVF program.

    abstract:PURPOSE:To test the effects of type of embryo transfer catheter, transfer difficulty, and observations after the transfer procedure on pregnancy and implantation rates in an IVF programme. METHODS:Patients were prepared for IVF using standard protocols. Embryo transfer was performed using either Edwards-Wallace or TDT...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1014054421789

    authors: De Placido G,Wilding M,Stina I,Mollo A,Alviggi E,Tolino A,Colacurci N,De ML,Marino M,Dale B

    更新日期:2002-01-01 00:00:00

  • Cost-effectiveness of recombinant versus urinary follicle-stimulating hormone in assisted reproduction techniques in the Spanish public health care system.

    abstract:PURPOSE:To evaluate the relative cost-effectiveness of recombinant and urinary follicle-stimulating hormone (FSH) in assisted reproduction techniques in the Spanish National Health Service. METHODS:Markov modelling was used to compare costs and outcomes of three complete treatment cycles using recombinant or urinary F...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1024899806149

    authors: Romeu A,Balasch J,Ruiz Balda JA,Barri PN,Daya S,Auray JP,Duru G,Beresniak A,Peinado JA

    更新日期:2003-08-01 00:00:00

  • Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis.

    abstract:PURPOSE:The purpose of this study was to evaluate the best protocol to prepare endometrium for frozen embryo replacement (FER) cycles. METHODS:This study is a systematic review and meta-analysis. Following PubMed and OvidSP search, a total of 1166 studies published after 1990 were identified following removal of dupli...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s10815-016-0787-0

    authors: Yarali H,Polat M,Mumusoglu S,Yarali I,Bozdag G

    更新日期:2016-10-01 00:00:00

  • Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers.

    abstract:PURPOSE:To evaluate clinical outcomes of frozen-thawed embryo transfer cycles when one or two blastocysts are transferred. METHODS:Retrospective chart review RESULTS:Two hundred forty-three frozen blastocyst transfer (FBT) cycles were analyzed. Clinical pregnancy rate (50.4% vs. 34.7%), live birth rate (45.8% vs. 30....

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-011-9551-7

    authors: Berin I,McLellan ST,Macklin EA,Toth TL,Wright DL

    更新日期:2011-07-01 00:00:00

  • Embryoscopy and karyotype findings of repeated miscarriages in recurrent pregnancy loss and spontaneous pregnancy loss.

    abstract:PURPOSE:The aim of the study was to assess cytogenetic and embryoscopic characteristics in subsequent miscarriages of spontaneous pregnancy losses (SPL) and recurrent pregnancy losses (RPL). METHODS:A retrospective cohort of 75 women was affected by repeated pregnancy loss. Of those, 34 had SPL, 24 primary RPL, and 17...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-018-1226-1

    authors: Feichtinger M,Reiner A,Hartmann B,Philipp T

    更新日期:2018-08-01 00:00:00

  • Application of touch FISH in the study of mosaic tetraploidy and maternal cell contamination in pregnancy losses.

    abstract:PURPOSE:karyotype is a well established technique in the study of spontaneous miscarriages but is associated with selective overgrowth of maternal cells and other culture artefact (spp) such as tetraploidy, which could mask the true karyotype of the conceptus. METHODS:328 cases of pregnancy losses were studied by kary...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-010-9460-1

    authors: Dória S,Lima V,Carvalho B,Moreira ML,Sousa M,Barros A,Carvalho F

    更新日期:2010-11-01 00:00:00

  • Decreased expression of MRE11 and RAD50 in testes from humans with spermatogenic failure.

    abstract:PURPOSE:To assess testicular mRNA and protein expression levels of MRE11 and RAD50 in human azoospermia patients. METHODS:Patients diagnosed with maturation arrest at the spermatocyte stage (MA) and Sertoli cell-only syndrome (SCOS) were recruited through diagnostic testicular biopsy. Patients with normal spermatogene...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-019-01686-5

    authors: Hu M,Li L,Liu S,Lou Y,Wang L,Le F,Li H,Wang Q,Lou H,Wang N,Jin F

    更新日期:2020-02-01 00:00:00

  • Seasonal changes in human sperm chromatin condensation.

    abstract:PURPOSE:The aim of this study was to investigate possible seasonal changes in human sperm parameters, especially chromatin condensation. METHOD:In a first run, 3155 patients attending the andrological outpatient clinic at the Centre of Dermatology and Andrology at Justus Liebig University, Giessen, Germany, from Janua...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1023/a:1016618405570

    authors: Henkel R,Menkveld R,Kleinhappl M,Schill WB

    更新日期:2001-07-01 00:00:00

  • Stress and reproductive failure: past notions, present insights and future directions.

    abstract:PROBLEM:Maternal stress perception is frequently alleged as a cause of infertility, miscarriages, late pregnancy complications or impaired fetal development. The purpose of the present review is to critically assess the biological and epidemiological evidence that considers the plausibility of a stress link to human re...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章,评审

    doi:10.1007/s10815-008-9206-5

    authors: Nakamura K,Sheps S,Arck PC

    更新日期:2008-02-01 00:00:00

  • Not many shoulders of giants to stand on these days.

    abstract:: ...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 社论

    doi:10.1007/s10815-018-1201-x

    authors: Albertini DF

    更新日期:2018-04-01 00:00:00

  • Morula transfer achieves better clinical outcomes than post-thawed cleavage embryos after overnight culture in frozen embryo transfer (FET) cycles.

    abstract:PURPOSE:This study aimed to investigate the clinical outcomes of morula stage transfer derived from post-thawed cleavage embryos undergoing overnight culture in frozen embryo transfer (FET) cycles. METHODS:We performed a retrospective study that included 392 FET cycles with 784 thawed embryos undergoing overnight cult...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-020-01708-7

    authors: Hui D,Han X,Wang X,Ren W,Lei X,Liu J,Dong L,Li H

    更新日期:2020-04-01 00:00:00

  • Body-mind-spirit intervention for IVF women.

    abstract:BACKGROUND:Literature supports the efficacy of psychosocial intervention for infertile women. An eastern body-mind-spirit group intervention has been developed to help infertile women in the Chinese population cope with the distress arising from IVF treatment. METHODS:The eastern body-mind-spirit group intervention ad...

    journal_title:Journal of assisted reproduction and genetics

    pub_type: 杂志文章

    doi:10.1007/s10815-005-6418-9

    authors: Chan CH,Chan CL,Ng SM,Ng EH,Ho PC

    更新日期:2005-12-01 00:00:00