当前位置： SCI文献检索 > JOURNAL OF ASSISTED REPRODUCTION AND GENETICS期刊下所有文献 > Live birth outcomes in infertile patients with class III and class IV obesity following fresh embryo transfer.

Live birth outcomes in infertile patients with class III and class IV obesity following fresh embryo transfer.

Abstract：

OBJECTIVE:Assess the effect of class III (body mass index [BMI, kg/m2] 40-49.9) and class IV obesity (≥ 50) on clinical pregnancy and live birth outcomes after first oocyte retrieval and fresh embryo transfer cycle. DESIGN:Cohort study SETTING: Academic center PATIENTS: Patients undergoing their first oocyte retrieval with planned fresh embryo transfer in our clinic between 01/01/2012 and 12/31/2018. Patients were stratified by BMI: 18.5-24.9 (n = 4913), 25-29.9 (n = 1566) 30-34.9 (n = 559), 35-39.9 (n = 218), and ≥ 40 (n = 114). INTERVENTION:None MAIN OUTCOME MEASURE: Live birth rate RESULTS: Following embryo transfer, there were no differences in pregnancy rates across all BMI groups (p value, linear trend = 0.86). However among pregnant patients, as BMI increased, a significant trend of a decreased live birth rate was observed (p value, test for linear trend = 0.004). Additionally, as BMI increased, a significant trend of an increased miscarriage rate was observed (p value, linear trend = < 0.001). Compared to the normal-weight cohort, women with a BMI ≥ 40 had a significantly higher rate of cancelled fresh transfers after retrieval (18.4% vs. 8.2%, OR 2.51; 95%CI 1.55-4.08). Among singleton deliveries, a significant trend of an increased c-section rate was identified as the BMI increased (p value, linear trend = <0.001). CONCLUSION:Overall, patients with a BMI > 40 have worse IVF treatment outcomes compared to normal-weight patients. After embryo transfer, their pregnancy rate is comparable to normal-weight women; however, their miscarriage rate is higher, leading to a lower live birth rate for pregnant women in this population. Patients with a BMI > 40 have a c-section rate that is 50% higher than normal-weight patients.

journal_name

J Assist Reprod Genet

journal_title

Journal of assisted reproduction and genetics

authors

Romanski PA,Bortoletto P,Magaoay B,Chung A,Rosenwaks Z,Spandorfer SD

doi

10.1007/s10815-020-02011-1

subject

Has Abstract

pub_date

2020-11-16 00:00:00

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-020-02011-1

pub_type

杂志文章

相关文献

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS文献大全
  • The effect of ease of transfer and type of catheter used on pregnancy and implantation rates in an IVF program.

    abstract：PURPOSE:To test the effects of type of embryo transfer catheter, transfer difficulty, and observations after the transfer procedure on pregnancy and implantation rates in an IVF programme. METHODS:Patients were prepared for IVF using standard protocols. Embryo transfer was performed using either Edwards-Wallace or TDT...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1014054421789

    authors： De Placido G,Wilding M,Stina I,Mollo A,Alviggi E,Tolino A,Colacurci N,De ML,Marino M,Dale B

    更新日期：2002-01-01 00:00:00

  • Association between FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China.

    abstract：PURPOSE:Polycystic ovary syndrome (PCOS) is a common endocrine disorder disease among women in reproductive-age. Since follicle stimulating hormone (FSH) exerts important biological functions, the association between PCOS and FSH receptor (FSHR) polymorphisms attracts wide attention. The aim of this study was to evalua...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0166-z

    authors： Wu XQ,Xu SM,Liu JF,Bi XY,Wu YX,Liu J

    更新日期：2014-03-01 00:00:00

  • Sex determination in single mouse blastomeres by polymerase chain reaction.

    abstract：:In sex determination of mammalian preimplantation embryos, viability of biopsied embryos and accuracy of sexing are together important. In consideration of this point, single blastomeres were mechanically isolated from mouse embryos using a micromanipulator and then sexed by polymerase chain reaction (PCR) using mouse...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF01207739

    authors： Han YM,Yoo OJ,Lee KK

    更新日期：1993-02-01 00:00:00

  • The role of genetic and autoimmune factors in premature ovarian failure.

    abstract：PURPOSE:To identify the role of both genetic (number of CGG repeats in the FMR1 gene) and autoimmune factors (anti-ovarian antibodies) in premature ovarian failure (POF). METHODS:In cross-sectional study, 78 women with POF were divided into 3 groups by the number of CGG repeats (less than 28, 28-36, more than 36) in a...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-9974-4

    authors： Shamilova NN,Marchenko LA,Dolgushina NV,Zaletaev DV,Sukhikh GT

    更新日期：2013-06-01 00:00:00

  • Reduced allele dropout in single-cell analysis for preimplantation genetic diagnosis of cystic fibrosis.

    abstract：BACKGROUND:For couples at risk of transmitting a known single-gene defect, preimplantation genetic diagnosis (PGD) allows the identification and transfer of only unaffected embryos following in vitro fertilisation (IVF), single-cell biopsy at about the eight-cell stage, and genetic analysis by PCR. This technique there...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02072529

    authors： Ray PF,Winston RM,Handyside AH

    更新日期：1996-02-01 00:00:00

  • Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential.

    abstract：OBJECTIVE:To evaluate the feasibility of adjusted mitochondrial DNA quantification in human embryos as a biomarker for implantation potential. DESIGN:Double-blind, observational, prospective analysis of an Asian population in a single university-affiliated in vitro fertilization center. A total of 1617 embryos derived...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01542-6

    authors： Lee YX,Chen CH,Lin SY,Lin YH,Tzeng CR

    更新日期：2019-09-01 00:00:00

  • Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR.

    abstract：:There are large variations in the number of oocytes within each woman, and biologically, the total quantity is at its maximum before the woman is born. Scientific knowledge is limited about factors controlling the oocyte pool and how to measure it. Within fertility clinics, there is no uniform agreement on the diagnos...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-017-1058-4

    authors： Pastore LM,Christianson MS,Stelling J,Kearns WG,Segars JH

    更新日期：2018-01-01 00:00:00

  • Clustering of monozygotic twinning in IVF.

    abstract：PURPOSE:The aim of this analysis was to study whether monozygotic twinning (MZT) events occur in clusters after IVF and, if so, to explore possible explanations for this clustering. METHODS:This is a retrospective cohort study carried out in a single, large university-affiliated reproductive medicine practice. Medical...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-015-0616-x

    authors： Vaughan DA,Ruthazer R,Penzias AS,Norwitz ER,Sakkas D

    更新日期：2016-01-01 00:00:00

  • Medical research and reproductive medicine in an ethical context: a critical commentary on the paper dealing with uterine lavage published by Munné et al.

    abstract：:A recent study published in Human Reproduction claimed that uterine lavage offers a non-surgical, minimally invasive strategy for the recovery of human embryos from fertile women who do not want or need IVF for medical reasons but who desire preimplantation genetic testing (PGT) for embryos. To prove this hypothesis, ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01954-9

    authors： Murtinger M,Wirleitner B,Hradecký L,Comploj G,Okhowat J,Spitzer D,Stadler J,Haidbauer R,Schuff M,Yildirim S,Soepenberg T,Eibner K,Gagsteiger F

    更新日期：2020-11-01 00:00:00

  • Oocyte cryopreservation for women with GATA2 deficiency.

    abstract：PURPOSE:To describe controlled ovarian stimulation (COS) in a population of women with GATA2 deficiency, a genetic bone marrow failure syndrome, prior to allogeneic hematopoietic stem cell transplant METHODS: This is a retrospective case series of nine women with GATA2 deficiency who underwent oocyte preservation at a ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1146-0

    authors： Zolton JR,Parikh TP,Hickstein DD,Holland SM,Hill MJ,DeCherney AH,Wolff EF

    更新日期：2018-07-01 00:00:00

  • Effect of Linolenic acid during in vitro maturation of ovine oocytes: embryonic developmental potential and mRNA abundances of genes involved in apoptosis.

    abstract：PURPOSE:To study the effect of α-linolenic acid (ALA) on meiotic maturation, mRNA abundance of apoptosis-related (Bax and Bcl-2) molecules, and blastocyst formation in ovine oocytes. METHODS:A preliminary experiment was conducted to analyze the concentration of ALA in "small" (≤2 mm) and "large" (≥6 mm) follicles usin...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-015-0439-9

    authors： Veshkini A,Asadi H,Khadem AA,Mohammadi-Sangcheshmeh A,Khazabi S,Aminafshar M,Deldar H,Soleimani M,Cinar MU

    更新日期：2015-04-01 00:00:00

  • Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection.

    abstract：PURPOSE:To investigate the relation between mutations in ciliopathy-related SPAG6 and RSPH3 and male infertility with severe asthenoteratospermia characterized by multiple flagellar malformations and reveal the intracytoplasmic sperm injection (ICSI) outcomes of those primary ciliary dyskinesia (PCD) patients. METHODS...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01721-w

    authors： Wu H,Wang J,Cheng H,Gao Y,Liu W,Zhang Z,Jiang H,Li W,Zhu F,Lv M,Liu C,Tan Q,Zhang X,Wang C,Ni X,Chen Y,Song B,Zhou P,Wei Z,Zhang F,He X,Cao Y

    更新日期：2020-04-01 00:00:00

  • Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis.

    abstract：PURPOSE:The purpose of this study was to evaluate the best protocol to prepare endometrium for frozen embryo replacement (FER) cycles. METHODS:This study is a systematic review and meta-analysis. Following PubMed and OvidSP search, a total of 1166 studies published after 1990 were identified following removal of dupli...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,meta分析,评审

    doi：10.1007/s10815-016-0787-0

    authors： Yarali H,Polat M,Mumusoglu S,Yarali I,Bozdag G

    更新日期：2016-10-01 00:00:00

  • Association between miR-146a C > G, miR-149 T > C, miR-196a2 T > C, and miR-499 A > G polymorphisms and susceptibility to idiopathic recurrent pregnancy loss.

    abstract：BACKGROUND:A growing body of evidence suggests that microRNAs play fundamental regulatory roles in embryo implantation and maintenance of pregnancy. The aim of this study was to investigate the possible association between miR-146a C > G, miR-149 T > C, miR-196a2 T > C, and miR-499 A > G polymorphisms and genetic susce...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01573-z

    authors： Alipour M,Abtin M,Hosseinzadeh A,Maleki M

    更新日期：2019-11-01 00:00:00

  • Morphologic and proliferative characteristics of goat type A spermatogonia in the presence of different sets of growth factors.

    abstract：PURPOSE:The present study by using different growth factors was aimed to develop the best practical culture condition for purification of goat undifferentiated SSCs and their colonization under in vitro and in vivo conditions. METHODS:The enzymatically isolated SSCs obtained from one month old goat testes were culture...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0301-5

    authors： Shirazi MS,Heidari B,Shirazi A,Zarnani AH,Jeddi-Tehrani M,Rahmati-Ahmadabadi M,Naderi MM,Behzadi B,Farab M,Sarvari A,Borjian-Boroujeni S,Akhondi MM

    更新日期：2014-11-01 00:00:00

  • Disparities in reproductive outcomes according to the endometrial preparation protocol in frozen embryo transfer : The risk of early pregnancy loss in frozen embryo transfer cycles.

    abstract：PURPOSE:The purpose of this study was to determine the effect of stimulated and artificial endometrial preparation protocols on reproductive outcomes in frozen embryo transfer (FET) cycles. METHODS:We performed a retrospective study of 1926 FET cycles over a 3.5-year period in the Fertility Unit at a University Hospit...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-017-1078-0

    authors： Hatoum I,Bellon L,Swierkowski N,Ouazana M,Bouba S,Fathallah K,Paillusson B,Bailly M,Boitrelle F,Alter L,Bergère M,Selva J,Wainer R

    更新日期：2018-03-01 00:00:00

  • Microinsemination techniques for the treatment of patients suffering agenesia of the vas deferens.

    abstract：:Thirty cycles of microsurgical epididymal sperm aspiration were performed on 27 patients presenting agenesia of the vas deferens. Two techniques of microinsemination were used, depending on the quality of the sperm preparation: subzonal sperm microinjection and microdroplet insemination. The results obtained by both m...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02070149

    authors： Gianaroli L,Magli MC,Colpi G,Vitali G,Fortini D,Negri L,Ferraretti AP

    更新日期：1996-04-01 00:00:00

  • Preimplantation genetic diagnosis of inherited cancer: familial adenomatous polyposis coli.

    abstract：PURPOSE:Our purpose was to achieve preimplantation genetic diagnosis (PGD) of the dominant cancer predisposition syndrome, familial adenomatous polyposis coli (FAPC), as an alternative to prenatal diagnosis. METHODS:The affected patient was superovulated and oocytes were retrieved and fertilized by intracytoplasmic sp...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1023008921386

    authors： Ao A,Wells D,Handyside AH,Winston RM,Delhanty JD

    更新日期：1998-03-01 00:00:00

  • Respirometric reserve capacity of cumulus cell mitochondria correlates with oocyte maturity.

    abstract：PURPOSE:Oocyte competence is critical in success of assisted reproduction. Metabolic signaling between oocyte and cumulus cells within the cumulus-oocyte complex procure oocyte development. This study evaluated the relationship between respirometric activity of cumulus cells and maturity of corresponding oocytes. METH...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1271-9

    authors： Anderson SH,Glassner MJ,Melnikov A,Friedman G,Orynbayeva Z

    更新日期：2018-10-01 00:00:00

  • Allogeneic ovarian transplantation using immunomodulator preimplantation factor (PIF) as monotherapy restored ovarian function in olive baboon.

    abstract：PURPOSE:Allogeneic ovarian transplantation may be an alternative in the future to oocyte donation in women with premature ovarian failure. The objectives of this study were to (a) evaluate allotransplantation feasibility for restoration of ovarian function and (b) assess efficacy of synthetic preimplantation factor (PI...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-017-1051-y

    authors： Feichtinger M,Barnea ER,Nyachieo A,Brännström M,Kim SS

    更新日期：2018-01-01 00:00:00

  • A comparison of the Cook single lumen immature ovum IVM needle to the Steiner-Tan pseudo double lumen flushing needle for oocyte retrieval for IVM.

    abstract：PURPOSE:This study compared the impact of using the Steiner-Tan pseudo double lumen needle for antral follicle oocyte retrieval to using a conventional non-flushing needle. The Steiner-Tan needle has a much smaller dead space than the needles commonly used for IVM oocyte retrievals. METHODS:This was a retrospective co...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0006-1

    authors： Rose BI,Laky D

    更新日期：2013-06-01 00:00:00

  • Endometriosis does not affect live birth rates of patients submitted to assisted reproduction techniques: analysis of the Latin American Network Registry database from 1995 to 2011.

    abstract：PURPOSE:The purpose of this study is to compare the results of ART treatment in patients with and without endometriosis in a large cohort of patients from different centers over an extented period of time. METHODS:This retrospective study is using data from patients undergoing 27,294 cycles of IVF/ICSI treatment betwe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1214-5

    authors： Murta M,Machado RC,Zegers-Hochschild F,Checa MA,Sampaio M,Geber S

    更新日期：2018-08-01 00:00:00

  • The effect of patient and semen characteristics on live birth rates following intrauterine insemination: a retrospective study.

    abstract：PURPOSE:To identify characteristics of female patients and of semen that were associated with live birth following intrauterine insemination (IUI). METHODS:Retrospective review of medical and laboratory results from 533 women who underwent IUI with partner's sperm from 1993 through 1995. RESULTS:Among 1728 cycles, 11...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1009402214820

    authors： Hendin BN,Falcone T,Hallak J,Nelson DR,Vemullapalli S,Goldberg J,Thomas AJ Jr,Agarwal A

    更新日期：2000-05-01 00:00:00

  • Influence of post-thaw culture on the developmental potential of human frozen embryos.

    abstract：PURPOSE:Apart from freezing/thawing related cryodamage, several additional factors have been identified as major players in the reduction of success rates after frozen embryo transfers. The post-thaw culture is particularly relevant as it may amplify environmental influences over a stressed embryo. In the present study...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9793-z

    authors： Rato ML,Gouveia-Oliveira A,Plancha CE

    更新日期：2012-08-01 00:00:00

  • Generic human menopausal gonadotropin (hMG) in place of more costly follicle-stimulating hormone (FSH) for routine ovulation induction.

    abstract：PURPOSE:A large part of infertility treatment involves the use of exogenous gonadotropins. The last decade has seen a progressive switch from human menopausal gonadotropin (hMG), the original gonadotropin product, to progressively more costly products, primarily or exclusively containing follicle-stimulating hormone (F...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1009477523136

    authors： Gleicher N,Karande V

    更新日期：2000-10-01 00:00:00

  • Diagnostic laparoscopy in primary and secondary infertility.

    abstract：PURPOSE:Our purpose was to compare the diagnostic efficacy of laparoscopy between primary and secondary infertility and to define a subgroup in which the positive findings are low. METHODS:A retrospective review of the cases of 206 infertile women who underwent laparoscopy was conducted. RESULTS:Eighty-two (39.8%) pa...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1022578019260

    authors： Hovav Y,Hornstein E,Almagor M,Yaffe C

    更新日期：1998-10-01 00:00:00

  • Neonatal outcome of early rescue ICSI and ICSI with ejaculated sperm.

    abstract：PURPOSE:To evaluate the impact of early rescue ICSI on neonatal outcome. METHODS:This retrospective study compared the neonatal outcome of early rescue ICSI and ICSI with ejaculated sperm, including 233 children who were conceived after early rescue ICSI and a control group of 906 children who were conceived after ICS...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0245-9

    authors： Chen L,Xu Z,Zhang N,Wang B,Chen H,Wang S,Sun H

    更新日期：2014-07-01 00:00:00

  • Vitamin E effect on controlled ovarian stimulation of unexplained infertile women.

    abstract：PURPOSE:To determine Vit E effect on the treatment outcomes of women with unexplained infertility undergoing controlled ovarian stimulation and intrauterine insemination (IUI). METHODS:The study group (Group A, n053) underwent controlled ovarian stimulation with clomiphene citrate with Vit E administration, 400 IU/day...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s10815-012-9714-1

    authors： Cicek N,Eryilmaz OG,Sarikaya E,Gulerman C,Genc Y

    更新日期：2012-04-01 00:00:00

  • Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure.

    abstract：PURPOSE:To characterize each chromosome's risk for being involved in embryonic aneuploidy. METHODS:This is a retrospective cohort study conducted at a single, academic center. The cohort consisted of 15,169 consecutive trophectoderm biopsies which then underwent comprehensive chromosome screening utilizing validated r...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0333-x

    authors： Franasiak JM,Forman EJ,Hong KH,Werner MD,Upham KM,Treff NR,Scott RT

    更新日期：2014-11-01 00:00:00

  • Relative expression of genes encoding SMAD signal transduction factors in human granulosa cells is correlated with oocyte quality.

    abstract：PURPOSE:To determine the expression of SMAD transcripts in human granulosa cells. METHODS:Luteinized mural granulosa cells were harvested from forty women undergoing oocyte retrieval, and RNAs were isolated. SMAD expression levels were determined by polymerase chain reaction (PCR) and quantitative real-time PCR (q-RTP...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-011-9609-6

    authors： Kuo FT,Fan K,Ambartsumyan G,Menon P,Ketefian A,Bentsi-Barnes IK,Pisarska MD

    更新日期：2011-09-01 00:00:00