Maternal C-reactive protein and in vitro fertilization (IVF) cycles.

Abstract:

:Embryo implantation is accompanied by a potent inflammatory response, and a gradient of cytokines and chemokines produced by endometrial cells supports the embryo-endometrial interaction. C-reactive protein (CRP) serves as an early marker of inflammation and recent studies have illustrated that controlled ovarian hyperstimulation (COH) could increase its levels. Interestingly, a high chance of pregnancy has been reported in women who had an elevated CRP level on the day of embryo transfer. It seems an elevated systemic inflammation in the in vitro fertilization (IVF) cycle can increase the implantation and pregnancy rates. However, the results regarding the association of CRP with ART outcomes are controversial. Therefore, in this review, we aimed to describe how CRP levels change during a cycle of IVF treatment and which factors can potentially affect this pattern of change. Furthermore, the association of CRP with ART outcomes has been discussed.

journal_name

J Assist Reprod Genet

authors

Diba-Bagtash F,Farshbaf-Khalili A,Ghasemzadeh A,Lotz L,Fattahi A,Shahnazi M,Dittrich R

doi

10.1007/s10815-020-01924-1

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

2635-2641

issue

11

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-020-01924-1

journal_volume

37

pub_type

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