Is Anacetrapib Better Than Its CETP Inhibitor Counterparts?

abstract：:Stress radionuclide myocardial perfusion imaging is a commonly used modality to evaluate patients with known or suspected coronary artery disease. The dual isotope rest thallium-201/stress technetium-99m sestamibi gated single-photon emission computed tomography protocol has gained increasing popularity for these appl...

journal_title：Cardiology in review

authors： Hachamovitch R

更新日期：1999-03-01 00:00:00

abstract：:This article provides a brief overview of several recently developed, emerging technologies and discusses their potential uses on clinical grounds. These new technologies include three-dimensional imaging, objective automated evaluation of ventricular function with acoustic quantification, assessment of regional ventr...

journal_title：Cardiology in review

authors： Mor-Avi V,Lang RM

更新日期：2001-05-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Myocardial infarction (MI) complicated by cardiogenic shock (MI-CS) is a major cause of cardiovascular morbidity and mortality. Predictors of outcomes in MI-CS include clinical, laboratory, radiologic variables, and management strategies. This article reviews the existing literature on short- and long-term predictors ...

journal_title：Cardiology in review

authors： Acharya D

更新日期：2018-09-01 00:00:00

abstract：:The complex mechanism of platelet activation creates an optimal target for pharmacological treatment in patients with acute coronary syndromes. Current antiplatelet medications that are used in addition to aspirin include the thienopyridines, clopidogrel and prasugrel, but there are several limitations to the use of t...

journal_title：Cardiology in review

authors： Nawarskas JJ,Clark SM

更新日期：2011-03-01 00:00:00

abstract：:The toll-like receptors (TLRs) are a class of transmembrane molecules that have important functions in both innate and acquired immunity. As part of the body's normal immune defense against microbial pathogens, stimulation of these receptors will trigger the inflammatory response cascade and the release of cytokines. ...

journal_title：Cardiology in review

authors： Erickson B,Sperber K,Frishman WH

更新日期：2008-11-01 00:00:00

abstract：:Acute decompensated heart failure (ADHF) is a common syndrome with diverse etiologies and precipitating factors, which is associated with significant morbidity and mortality. Tremendous resources are used in treating this syndrome, with few prospectively designed clinical trials to guide therapy. Patients suffering fr...

journal_title：Cardiology in review

authors： Sanchez CE,Richards DR

更新日期：2011-05-01 00:00:00

abstract：:Primary pulmonary hypertension and cor pulmonale represent forms of precapillary pulmonary hypertension due to intrinsic lung disease. In the case of primary pulmonary hypertension, this is due to disease of the pulmonary vasculature while cor pulmonale is related to diseases of the pulmonary vasculature, airways, or ...

journal_title：Cardiology in review

authors： Lehrman S,Romano P,Frishman W,Rashid A,Dobkin J,Reichel J

更新日期：2002-09-01 00:00:00

abstract：:Cardiac allograft vasculopathy (CAV), characterized by diffuse intimal thickening and luminal narrowing in the arteries of the allograft, is the leading cause of morbidity and mortality in cardiac transplant recipients. Many transplant centers perform routine annual surveillance coronary angiography. However, angiogra...

journal_title：Cardiology in review

authors： Cai Q,Rangasetty UC,Barbagelata A,Fujise K,Koerner MM

更新日期：2011-01-01 00:00:00

abstract：:Patients living with the human immunodeficiency virus (HIV) are at risk for dyslipidemia as a result of the disease itself and from certain classes of antiretroviral therapy. The protease inhibitors and non-nucleoside reverse transcription inhibitors have been associated with elevated triglycerides, total, and low-den...

journal_title：Cardiology in review

authors： Ray GM

更新日期：2009-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is a common cardiac arrhythmia with significant morbidity and public health cost. Because of limitations of efficacy and safety of conventional antiarrhythmic agents, alternative therapies for AF are needed. The potential antiarrhythmic properties of lipid-altering therapy, including the 3-hyd...

journal_title：Cardiology in review

authors： Bachmann JM,Majmudar M,Tompkins C,Blumenthal RS,Marine JE

更新日期：2008-07-01 00:00:00

abstract：:Mechanical valve thrombosis is a life-threatening event. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. This is associated with a therapeutic dilemma. Continued anticoagulation with warfarin throughout the first trimester can result in fetopathi...

journal_title：Cardiology in review

authors： Behrendt P,Schwartzkopff B,Perings S,Gerhardt A,Zotz RB,Strauer BE

更新日期：2002-11-01 00:00:00

abstract：:Renovascular hypertension caused by renal artery stenosis accounts for a small portion of overall hypertension but remains important as the most common potentially curable form of high blood pressure. Diagnosis depends on developing an index of suspicion for renovascular hypertension based on the history and physical ...

journal_title：Cardiology in review

authors： Klassen PS,Svetkey LP

更新日期：2000-01-01 00:00:00

abstract：:Interleukin 1β (IL-1β) is a proinflammatory cytokine that has been implicated in a number of rheumatologic and inflammatory conditions. The production and secretion of IL-1β from inflammatory cells is a tightly regulated process that has been extensively described and studied. In recent years, IL-1β has been associate...

journal_title：Cardiology in review

authors： McCarty S,Frishman W

更新日期：2014-07-01 00:00:00

abstract：:Cardiac computed tomographic angiography (CCTA) has evolved at an unprecedented pace over the past decade, during which time it has proven to be an accurate and effective tool for imaging of the heart in a growing list of clinical applications. However, the rapid growth in the use of CT imaging in general has prompted...

journal_title：Cardiology in review

authors： Entrikin DW,Leipsic JA,Carr JJ

更新日期：2011-07-01 00:00:00

abstract：:The obesity epidemic has reached unprecedented proportions in Western society. Evidence continues to accumulate that obesity is associated with significant morbidity and mortality and in particular that it is an independent risk factor for cardiovascular disease (CVD). The association of obesity with CVD and its risk ...

journal_title：Cardiology in review

authors： Melanson KJ,McInnis KJ,Rippe JM,Blackburn G,Wilson PF

更新日期：2001-07-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of morbidity and mortality among women in industrialized nations. Optimizing cardiovascular risk reduction is therefore of paramount importance, particularly among postmenopausal women, in whom the incidence of cardiovascular disease is highest. Accumulated data from a serie...

journal_title：Cardiology in review

authors： Mostaghel E,Waters D

更新日期：2003-01-01 00:00:00

abstract：:Reverse redistribution is a well-known pattern found when performing thallium myocardial scintigraphy, and it has been implicated as an indicator of myocardial ischemia. Much more rarely, when using technetium compounds, which do not redistribute, a similar pattern is noted after the second injection of the radiotrace...

journal_title：Cardiology in review

authors： Antonopoulos A,Galanopoulou K,Katsafados I,Siantos E

更新日期：2004-05-01 00:00:00

abstract：:The literature on the relationship between work-related psychosocial factors and the development of ischemic heart disease (IHD) was systematically reviewed: 33 articles presented 51 analyses of studies involving male participants, 18 analyses involving female participants, and 8 analyses with both genders. Twenty of ...

journal_title：Cardiology in review

authors： Eller NH,Netterstrøm B,Gyntelberg F,Kristensen TS,Nielsen F,Steptoe A,Theorell T

更新日期：2009-03-01 00:00:00

abstract：:We report a case of spontaneous coronary artery rupture associated with amphetamine abuse in a 31-year-old woman. The patient presented to the emergency department with sudden onset of central chest pain and a normal electrocardiogram. Cardiac enzymes were consistent with acute myocardial infarction. Drug screening wa...

journal_title：Cardiology in review

authors： Brennan K,Shurmur S,Elhendy A

更新日期：2004-09-01 00:00:00

abstract：:Valvular endocarditis after percutaneous coronary intervention is unusual. We report a new case of mitral valve endocarditis after stent implantation to a saphenous vein graft. ...

journal_title：Cardiology in review

authors： Palmer ND,Ramsdale DR

更新日期：2005-05-01 00:00:00

abstract：:Arsenic is a ubiquitously dispersed metalloid that has been implicated as the cause of various adverse health effects. Human exposure to arsenic primarily occurs through contaminated drinking water and dietary intake of rice and grains, posing a great public health risk to millions of people worldwide. High levels of ...

journal_title：Cardiology in review

authors： Kononenko M,Frishman WH

更新日期：2020-09-15 00:00:00

abstract：:Myocarditis represents a heterogeneous final common pathway for myocardial inflammation of diverse etiologies and accounts for up to one-third of cases of dilated cardiomyopathy. The pathophysiology of viral myocarditis can be disaggregated into the effects of direct viral mediated injury, triggered acute and chronic ...

journal_title：Cardiology in review

authors： Ellis CR,Di Salvo T

更新日期：2007-07-01 00:00:00

abstract：:In this article, we critically evaluate the evidence relating to the effects of the Mediterranean diet (MD) on the risk of cardiovascular disease (CVD). Strong evidence indicating that the MD prevents CVD has come from prospective cohort studies. However, there is only weak supporting evidence from randomized controll...

journal_title：Cardiology in review

authors： Temple NJ,Guercio V,Tavani A

更新日期：2019-05-01 00:00:00

abstract：:The differentiation of left ventricular pseudoaneurysm from true aneurysm is sometimes difficult. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is clinically impo...

journal_title：Cardiology in review

authors： Cho MN,Mehta SK,Matulevicius S,Weinstein D,Wait MA,McGuire DK

更新日期：2006-11-01 00:00:00

abstract：:Saphenous vein graft (SVG) disease after coronary artery bypass grafting (CABG) occurs in three phases: thrombosis, intimal hyperplasia, and atherosclerosis. Within the first month, thrombosis plays a major role. From month 1 to month 12, intimal hyperplasia occurs. Beyond 12 months, atherosclerosis becomes the primar...

journal_title：Cardiology in review

authors： Kim FY,Marhefka G,Ruggiero NJ,Adams S,Whellan DJ

更新日期：2013-03-01 00:00:00

abstract：:In 1992, Brugada and Brugada reported a distinct subgroup of patients with episodes of "idiopathic"polymorphic ventricular tachycardia or ventricular fibrillation characterized by a unique electrocardiographic (ECG) pattern, which consisted of right bundle branch block and ST-segment elevation from V1 to V2-V3. As in ...

journal_title：Cardiology in review

authors： Corrado D,Buja G,Basso C,Nava A,Thiene G

更新日期：1999-07-01 00:00:00

abstract：:Heart valve prostheses carry a risk for thrombosis and require an antithrombotic strategy to prevent stroke, systemic embolism, and prosthetic valve thrombosis. Contemporary randomized trials to guide the clinician on the optimal anticoagulant treatment are scarce, and the validity of the historical data for current r...

journal_title：Cardiology in review

authors： Hermans H,Vanassche T,Herijgers P,Meuris B,Herregods MC,Van de Werf F,Verhamme P

更新日期：2013-01-01 00:00:00

abstract：:Abdominal aortic aneurysm is a multifactorial disease with genetic risk factors and an immunologic component. Immune cells, including macrophages, neutrophils, mast cells, B- and T- lymphocytes, along with vascular smooth muscle cells and adventitial fibroblasts, produce cytokines and enzymes, promoting an inflammator...

journal_title：Cardiology in review

authors： Rizas KD,Ippagunta N,Tilson MD 3rd

更新日期：2009-09-01 00:00:00

abstract：:The presence of pulmonary arterial hypertension (PAH) in pregnancy is rare and signifies a high-risk pregnancy. Although the majority of mothers have knowledge of their condition before pregnancy, approximately one-third of patients are diagnosed during pregnancy. Termination of pregnancy should be discussed, and is o...

journal_title：Cardiology in review

authors： Martínez MV,Rutherford JD

更新日期：2013-07-01 00:00:00