Periprocedural Management of Direct Oral Anticoagulants Surrounding Cardioversion and Invasive Electrophysiological Procedures.

Abstract:

:As direct oral anticoagulants (DOACs) have demonstrated favorable efficacy and safety outcomes compared with vitamin K antagonists for the treatment and prevention of venous thromboembolism and the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, their role in the management of anticoagulation during electrophysiological procedures continues to evolve. At present, guidelines are limited regarding specific recommendations for the use of DOACs in these clinical settings. Here, we review available data regarding the risks and benefits associated with various periprocedural anticoagulation management approaches when patients receiving DOACs undergo electrophysiologic procedures including cardioversion, ablation, and device implantation. This discussion is intended to provide clinicians with an overview of available evidence and best practices to minimize the risk of both thromboembolic and bleeding events in the periprocedural setting.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Finks SW,Dobesh PP,Trujillo TC,Crossley GH

doi

10.1097/CRD.0000000000000188

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

245-254

issue

5

eissn

1061-5377

issn

1538-4683

journal_volume

26

pub_type

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