Antithrombotic therapy in patients with heart valve prostheses.

Abstract:

:Heart valve prostheses carry a risk for thrombosis and require an antithrombotic strategy to prevent stroke, systemic embolism, and prosthetic valve thrombosis. Contemporary randomized trials to guide the clinician on the optimal anticoagulant treatment are scarce, and the validity of the historical data for current recommendations can be questioned in view of the changes in valve prostheses, the patient population, and antithrombotic therapies. This limited evidence from clinical trials translates into divergent recommendations from the different scientific societies on the optimal intensity of oral anticoagulation and on the indication for antiplatelet therapy. The availability of new antithrombotic agents and the unclear thrombotic risk of the currently used prostheses underscore the need to redefine antithrombotic treatment in patients with heart valve prostheses.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Hermans H,Vanassche T,Herijgers P,Meuris B,Herregods MC,Van de Werf F,Verhamme P

doi

10.1097/CRD.0b013e3182638578

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

27-36

issue

1

eissn

1061-5377

issn

1538-4683

journal_volume

21

pub_type

杂志文章,评审
  • Sudden Cardiac Death in Hypertrophic Cardiomyopathy.

    abstract::Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affect...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000184

    authors: Adamczak DM,Oko-Sarnowska Z

    更新日期:2018-05-01 00:00:00

  • A Review of Remdesivir for COVID-19: Data to Date.

    abstract::Severe acute respiratory coronavirus-2 (SARS-CoV-2) is responsible for one of the greatest public health challenges of our lifetime, the coronavirus disease 2019 (COVID-19) pandemic. Because of the complicated postinfection sequelae and grave consequences, the search for effective therapies has become a worldwide prio...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000337

    authors: Mehta M,Shyh GI

    更新日期:2020-11-01 00:00:00

  • Confusion in revascularization: are women different and why?

    abstract::Cardiovascular disease is the leading cause of death in women in most developed countries of the world. Even though cardiovascular deaths of men in the United States have been declining, until recently the number of cardiovascular deaths in US women was on the rise, with 1 in 3 women dying from heart disease. Over the...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e31815cb185

    authors: Dullum MK,Dullum MK

    更新日期:2008-01-01 00:00:00

  • Care of the Post-CABG Patient.

    abstract::An estimated 400,000 coronary artery bypass graft operations are performed annually in the United States. Saphenous vein grafts are the most commonly used conduits; however, graft failure is common. In contrast, left internal mammary artery grafts have more favorable long-term patency rates. Guidelines recommend aggre...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000261

    authors: Collins D,Goldberg S

    更新日期:2020-01-01 00:00:00

  • The prognostic impact of myocardial late gadolinium enhancement.

    abstract::Cardiovascular magnetic resonance using late gadolinium enhancement (LGE) provides a unique opportunity to assess myocardial tissue in vivo. LGE enables tissue characterization in ischemic and nonischemic cardiomyopathies and other cardiac diseases. LGE is associated with adverse clinical outcomes across a range of di...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000002

    authors: Panovsky R,Pleva M,Feitova V,Kruzliak P,Meluzin J,Kincl V

    更新日期:2014-05-01 00:00:00

  • Women do benefit from lipid lowering: latest clinical trial data.

    abstract::Cardiovascular disease is the leading cause of morbidity and mortality among women in industrialized nations. Optimizing cardiovascular risk reduction is therefore of paramount importance, particularly among postmenopausal women, in whom the incidence of cardiovascular disease is highest. Accumulated data from a serie...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/00045415-200301000-00003

    authors: Mostaghel E,Waters D

    更新日期:2003-01-01 00:00:00

  • Epidemiology of atherothrombotic disease and the effectiveness and risks of antiplatelet therapy: race and ethnicity considerations.

    abstract::Cardiovascular disease is the leading cause of death in the United States, accounting for approximately 60% of total mortality in 2002. There is evidence that race and ethnicity is a risk factor for atherothrombotic events. Blacks have a greater risk of complications from coronary heart disease and unstable angina, wi...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e31815685fa

    authors: Saunders E,Ofili E

    更新日期:2008-03-01 00:00:00

  • Myocardial viability and microvascular obstruction: role of cardiac magnetic resonance imaging.

    abstract::Established coronary artery disease has a prevalence of 7% in adult Americans, accounting for 16 million people. As morbidity and mortality rates have risen, research efforts to identify the pathophysiologic mechanisms of systolic dysfunction have risen in parallel. The current goal is to develop new therapeutic strat...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000024

    authors: Romero J,Lupercio F,Haramati LB,Garcia MJ,Lucariello RJ

    更新日期:2014-09-01 00:00:00

  • Vorapaxar: A Protease-Activated Receptor Antagonist for the Prevention of Thrombotic Events.

    abstract::Antiplatelet therapy reduces the risks for cardiovascular morbidity and mortality in patients with atherosclerotic disease, and it is also beneficial in managing peripheral arterial disease (PAD). These agents work through various therapeutic pathways to achieve antithrombotic effects. Although single- or two-drug reg...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000075

    authors: Lam S,Tran T

    更新日期:2015-09-01 00:00:00

  • Idiopathic pulmonary arterial hypertension in childhood.

    abstract::The introduction of new medicines to treat pulmonary vascular disease has renewed interest in the management of children with idiopathic pulmonary arterial hypertension. We now have a practical classification of pulmonary hypertension, improved diagnostic techniques, and internationally recognized diagnostic and manag...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e3181ce03df

    authors: Haworth SG

    更新日期:2010-03-01 00:00:00

  • Epigenetic regulation in heart failure: part II DNA and chromatin.

    abstract::Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000074

    authors: DiSalvo TG

    更新日期:2015-11-01 00:00:00

  • Recent advances in echocardiographic evaluation of left ventricular anatomy, perfusion, and function.

    abstract::This article provides a brief overview of several recently developed, emerging technologies and discusses their potential uses on clinical grounds. These new technologies include three-dimensional imaging, objective automated evaluation of ventricular function with acoustic quantification, assessment of regional ventr...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/00045415-200105000-00008

    authors: Mor-Avi V,Lang RM

    更新日期:2001-05-01 00:00:00

  • Interleukin 1β: a proinflammatory target for preventing atherosclerotic heart disease.

    abstract::Interleukin 1β (IL-1β) is a proinflammatory cytokine that has been implicated in a number of rheumatologic and inflammatory conditions. The production and secretion of IL-1β from inflammatory cells is a tightly regulated process that has been extensively described and studied. In recent years, IL-1β has been associate...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000022

    authors: McCarty S,Frishman W

    更新日期:2014-07-01 00:00:00

  • Neprilysin Inhibition and the Treatment of Heart Failure: Recent Steps in the Right Direction.

    abstract::Numerous investigators have attempted to target the natriuretic peptide system in the treatment of heart failure since it was first described over 30 years ago. The history of neprilysin inhibition as a treatment for heart failure has been characterized by numerous setbacks. Recently, the PARADIGM-HF trial has shown f...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000169

    authors: Bartell N,Frishman WH

    更新日期:2017-11-01 00:00:00

  • Chest pain from gastroesophageal reflux disease in patients with coronary artery disease.

    abstract::Management of patients with coronary artery disease is a major challenge for physicians, patients, and the healthcare system. Chest pain experienced by patients with coronary disease can be of noncardiac origin, and symptoms frequently related to gastroesophageal etiologies. The distal esophagus and the heart share a ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/01.crd.0000148844.13702.ce

    authors: Liuzzo JP,Ambrose JA

    更新日期:2005-07-01 00:00:00

  • Percutaneous mitral heart valve repair--MitraClip.

    abstract::Mitral regurgitation (MR) is the most common cardiac valvular disease in the United States. Approximately 4 million people have severe MR and roughly 250,000 new diagnoses of MR are made each year. Mitral valve surgery is the only treatment that prevents progression of heart failure and provides sustained symptomatic ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000036

    authors: Doshi JV,Agrawal S,Garg J,Paudel R,Palaniswamy C,Doshi TV,Gotsis W,Frishman WH

    更新日期:2014-11-01 00:00:00

  • Brown adipose tissue thermogenesis: β3-adrenoreceptors as a potential target for the treatment of obesity in humans.

    abstract::It has been shown in rodents and newborn babies that brown adipose tissue (BAT) plays an important role in the generation of heat for maintenance of core body temperature. BAT is responsible for the process of adaptive thermogenesis, which involves heat generation in response to a drop in the environment's temperature...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e31829cabff

    authors: Mund RA,Frishman WH

    更新日期:2013-11-01 00:00:00

  • Work-related psychosocial factors and the development of ischemic heart disease: a systematic review.

    abstract::The literature on the relationship between work-related psychosocial factors and the development of ischemic heart disease (IHD) was systematically reviewed: 33 articles presented 51 analyses of studies involving male participants, 18 analyses involving female participants, and 8 analyses with both genders. Twenty of ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e318198c8e9

    authors: Eller NH,Netterstrøm B,Gyntelberg F,Kristensen TS,Nielsen F,Steptoe A,Theorell T

    更新日期:2009-03-01 00:00:00

  • Coronary artery rupture associated with amphetamine abuse.

    abstract::We report a case of spontaneous coronary artery rupture associated with amphetamine abuse in a 31-year-old woman. The patient presented to the emergency department with sudden onset of central chest pain and a normal electrocardiogram. Cardiac enzymes were consistent with acute myocardial infarction. Drug screening wa...

    journal_title:Cardiology in review

    pub_type: 杂志文章

    doi:10.1097/01.crd.0000132372.38506.45

    authors: Brennan K,Shurmur S,Elhendy A

    更新日期:2004-09-01 00:00:00

  • Chagas heart disease: report on recent developments.

    abstract::Chagas disease, caused by the parasite Trypanosoma cruzi, is an important cause of cardiac disease in endemic areas of Latin America. It is now being diagnosed in nonendemic areas because of immigration. Typical cardiac manifestations of Chagas disease include dilated cardiomyopathy, congestive heart failure, arrhythm...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e31823efde2

    authors: Machado FS,Jelicks LA,Kirchhoff LV,Shirani J,Nagajyothi F,Mukherjee S,Nelson R,Coyle CM,Spray DC,de Carvalho AC,Guan F,Prado CM,Lisanti MP,Weiss LM,Montgomery SP,Tanowitz HB

    更新日期:2012-03-01 00:00:00

  • Ayurveda and Yoga in Cardiovascular Diseases.

    abstract::Ayurveda is derived from 2 Sanskrit words, namely, "Ayus" and "Veda," meaning life and knowledge, respectively. It literally means science of life. Ayurveda, of which yoga is an integral part, is widely practiced in India and is gaining acceptance in many countries around the world. It is a comprehensive and a holisti...

    journal_title:Cardiology in review

    pub_type: 杂志文章

    doi:10.1097/01.crd.0000128730.31658.36

    authors: Mamtani R,Mamtani R

    更新日期:2004-09-01 00:00:00

  • Lipid-altering therapy and atrial fibrillation.

    abstract::Atrial fibrillation (AF) is a common cardiac arrhythmia with significant morbidity and public health cost. Because of limitations of efficacy and safety of conventional antiarrhythmic agents, alternative therapies for AF are needed. The potential antiarrhythmic properties of lipid-altering therapy, including the 3-hyd...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e318177271d

    authors: Bachmann JM,Majmudar M,Tompkins C,Blumenthal RS,Marine JE

    更新日期:2008-07-01 00:00:00

  • Cardiac rupture after myocardial infarction: new insights from murine models.

    abstract::Cardiac rupture after a myocardial infarction is an uncommon event with devastating consequences. Although the clinical features of rupture have been described, the genetic and molecular influences on this outcome in patients are less certain. In mice, at least 17 genetic models have been developed that enhance or sup...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e3181bf4ab4

    authors: Sane DC,Mozingo WS,Becker RC

    更新日期:2009-11-01 00:00:00

  • Short QT Syndrome in Current Clinical Practice.

    abstract::Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000091

    authors: Khera S,Jacobson JT

    更新日期:2016-07-01 00:00:00

  • Third-Generation LVADs: Has Anything Changed?

    abstract::The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricul...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000268

    authors: Levine A,Gass A

    更新日期:2019-11-01 00:00:00

  • Apixaban: a new factor Xa inhibitor for stroke prevention in patients with nonvalvular atrial fibrillation.

    abstract::Atrial fibrillation (AF) is an independent risk factor for ischemic stroke occurrence, severity, recurrence, and mortality. Anticoagulation therapy for the prevention of thromboembolism is critical in patients with AF who are at risk of stroke. Warfarin has been an efficacious anticoagulant for this purpose, but its u...

    journal_title:Cardiology in review

    pub_type: 杂志文章

    doi:10.1097/CRD.0b013e318293d6e6

    authors: Lam S

    更新日期:2013-07-01 00:00:00

  • Radiation-induced heart disease.

    abstract::Radiation-induced heart disease (RIHD) is becoming an increasing concern for patients and clinicians alike as the use of radiation therapy for the treatment of certain malignancies increases, and patient mortality secondary to neoplasms of the thorax, in particular Hodgkin's lymphoma and breast cancer, decreases. The ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e3182431c23

    authors: Filopei J,Frishman W

    更新日期:2012-07-01 00:00:00

  • What a physician needs to know about cost-effectiveness.

    abstract::The cost of medical care in the United States continues to spiral upward, partly as a result of new technological breakthroughs that promise improved length of life and quality of life for patients. But how good are these treatments in everyday practice? How do we make policies for adopting innovations that improve ou...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/00045415-200008020-00006

    authors: Heidenreich PA,Lee TT

    更新日期:2000-03-01 00:00:00

  • Treating Diuretic Resistance: An Overview.

    abstract::Loop diuretics are central to the management of fluid overload in acute decompensated heart failure. However, a variance in the response to loop diuretics can alter a patient's clinical course and has an adverse effect on clinical outcomes. Thus, a diminished response to loop diuretics is an important clinical issue. ...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0000000000000116

    authors: Bowman BN,Nawarskas JJ,Anderson JR

    更新日期:2016-09-01 00:00:00

  • Saphenous vein graft disease: review of pathophysiology, prevention, and treatment.

    abstract::Saphenous vein graft (SVG) disease after coronary artery bypass grafting (CABG) occurs in three phases: thrombosis, intimal hyperplasia, and atherosclerosis. Within the first month, thrombosis plays a major role. From month 1 to month 12, intimal hyperplasia occurs. Beyond 12 months, atherosclerosis becomes the primar...

    journal_title:Cardiology in review

    pub_type: 杂志文章,评审

    doi:10.1097/CRD.0b013e3182736190

    authors: Kim FY,Marhefka G,Ruggiero NJ,Adams S,Whellan DJ

    更新日期:2013-03-01 00:00:00