Abstract:
:Radiation-induced heart disease (RIHD) is becoming an increasing concern for patients and clinicians alike as the use of radiation therapy for the treatment of certain malignancies increases, and patient mortality secondary to neoplasms of the thorax, in particular Hodgkin's lymphoma and breast cancer, decreases. The spectrum of pathology affecting the heart spans from acute to chronic and can affect almost all facets of the heart, including but not restricted to the pericardial sac, coronary arteries, myocardium, and heart valves. Significant research has been conducted over the past 40 years to further understand the toxic effects of radiation therapy and those protective methods that could curtail these adverse reactions. This article will focus on RIHD, the pathophysiological mechanisms for RIHD, the clinical presentations, and current and future directions for attempting to reduce the incidence of this condition.
journal_name
Cardiol Revjournal_title
Cardiology in reviewauthors
Filopei J,Frishman Wdoi
10.1097/CRD.0b013e3182431c23subject
Has Abstractpub_date
2012-07-01 00:00:00pages
184-8issue
4eissn
1061-5377issn
1538-4683journal_volume
20pub_type
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pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Cardiology in review
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更新日期:2010-05-01 00:00:00
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journal_title:Cardiology in review
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