Resting measures and physiological responses to exercise for the determination of prognosis in patients with chronic heart failure: useful tools for clinical decision-making.

Abstract:

:Despite recent advances in the management of chronic heart failure (CHF), the prognosis of many of these patients remains dire. The need for an accurate prognosis in these patients has led to the identification of several indicators purported to represent the impact of the disease. Such indicators often are obtained at rest and are not always accurate at determining the clinical status of CHF patients. As a result, the relationship between prognostic indicators and clinical outcomes is frequently weak. On the other hand, physiological responses to acute exercise may unmask patients with the worst clinical status and identify those at increased risk of poor outcomes. Therefore, the present review appraises the value of several prognostic indicators for patients with CHF collected at rest and in response to exercise. In particular, it contrasts the value and accuracy of predictors of mortality widely used in clinical settings, such as oxygen uptake, ventilatory efficiency, and left ventricular ejection fraction, with new and more direct indicators of ventricular systolic and diastolic function.

journal_name

Cardiol Rev

journal_title

Cardiology in review

authors

Jorge Alves A,Ribeiro F,Sagiv M,Eynon N,Yamin C,Sagiv M,Oliveira J

doi

10.1097/CRD.0b013e3181c4ae0c

subject

Has Abstract

pub_date

2010-07-01 00:00:00

pages

171-7

issue

4

eissn

1061-5377

issn

1538-4683

pii

00045415-201007000-00002

journal_volume

18

pub_type

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