Pulmonary artery hypertension: caveolin-1 and eNOS interrelationship: a new perspective.

abstract：:Vitamin K antagonists (VKAs) such as warfarin have traditionally been the major therapeutic option for anticoagulation in clinical practice. VKAs are effective and extensively recommended for the prevention of venous and arterial thromboembolism in cardiovascular disease. Despite its effectiveness, warfarin is limited...

journal_title：Cardiology in review

authors： Maan A,Padmanabhan R,Shaikh AY,Mansour M,Ruskin JN,Heist EK

更新日期：2012-09-01 00:00:00

abstract：:Cardiac rupture after a myocardial infarction is an uncommon event with devastating consequences. Although the clinical features of rupture have been described, the genetic and molecular influences on this outcome in patients are less certain. In mice, at least 17 genetic models have been developed that enhance or sup...

journal_title：Cardiology in review

authors： Sane DC,Mozingo WS,Becker RC

更新日期：2009-11-01 00:00:00

abstract：:Chagas disease, caused by the parasite Trypanosoma cruzi, is an important cause of cardiac disease in endemic areas of Latin America. It is now being diagnosed in nonendemic areas because of immigration. Typical cardiac manifestations of Chagas disease include dilated cardiomyopathy, congestive heart failure, arrhythm...

journal_title：Cardiology in review

authors： Machado FS,Jelicks LA,Kirchhoff LV,Shirani J,Nagajyothi F,Mukherjee S,Nelson R,Coyle CM,Spray DC,de Carvalho AC,Guan F,Prado CM,Lisanti MP,Weiss LM,Montgomery SP,Tanowitz HB

更新日期：2012-03-01 00:00:00

abstract：:Atrial fibrillation (AF) is an independent risk factor for ischemic stroke occurrence, severity, recurrence, and mortality. Anticoagulation therapy for the prevention of thromboembolism is critical in patients with AF who are at risk of stroke. Warfarin has been an efficacious anticoagulant for this purpose, but its u...

journal_title：Cardiology in review

authors： Lam S

更新日期：2013-07-01 00:00:00

abstract：:The effect of an ongoing educational program on the use of cardiovascular drugs in patients with coronary artery disease without contraindications to these drugs seen in an academic cardiology clinic was assessed in 100 patients seen during the 6-month period prior to the educational program and in 200 patients seen 9...

journal_title：Cardiology in review

authors： Nayak D,Aronow WS

更新日期：2005-03-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affect...

journal_title：Cardiology in review

authors： Adamczak DM,Oko-Sarnowska Z

更新日期：2018-05-01 00:00:00

abstract：:Atherosclerosis develops and rapidly progresses in saphenous veins grafts after coronary bypass surgery. In contrast to native coronary artery, percutaneous revascularization does not impede the progression of saphenous vein atherosclerosis and saphenous vein graft failure commonly ensues. The protracted patency of ar...

journal_title：Cardiology in review

authors： Motwani A,Ayinapudi K,Singh T,Maini R,Hendel R,Le Jemtel TH

更新日期：2020-09-01 00:00:00

abstract：:The increased life expectancy of women living in industrialized countries is associated with an increase in diseases dependent or facilitated by a state of estrogen deficiency, such as cardiovascular and cerebrovascular diseases. Several studies have shown that estrogen replacement therapy reduces the occurrence of co...

journal_title：Cardiology in review

authors： Rosano GM,Fini M

更新日期：2002-01-01 00:00:00

abstract：:Mitral regurgitation (MR) is the most common cardiac valvular disease in the United States. Approximately 4 million people have severe MR and roughly 250,000 new diagnoses of MR are made each year. Mitral valve surgery is the only treatment that prevents progression of heart failure and provides sustained symptomatic ...

journal_title：Cardiology in review

authors： Doshi JV,Agrawal S,Garg J,Paudel R,Palaniswamy C,Doshi TV,Gotsis W,Frishman WH

更新日期：2014-11-01 00:00:00

abstract：:Differences in the overall mortality for acute infarction in women vs men have been appreciated for some time. Some of these differences are based on the age at the time of presentation of women compared with men. Excess mortality in women is most clear at the younger end of the age spectrum. More careful examination ...

journal_title：Cardiology in review

authors： Feldman T,Silver R

更新日期：2000-07-01 00:00:00

abstract：:Glucose-insulin-potassium (GIK) utilization in the treatment of acute myocardial infarction (AMI) has been studied since the early 1960s with varying results. It is well established that ischemic myocardial cells convert from aerobic metabolism of glucose to toxic anaerobic free fatty acid (FFA) metabolism for the pro...

journal_title：Cardiology in review

authors： Leos CL,Griego JE,Anderson JR

更新日期：2005-09-01 00:00:00

abstract：:Antiplatelet therapy reduces the risks for cardiovascular morbidity and mortality in patients with atherosclerotic disease, and it is also beneficial in managing peripheral arterial disease (PAD). These agents work through various therapeutic pathways to achieve antithrombotic effects. Although single- or two-drug reg...

journal_title：Cardiology in review

authors： Lam S,Tran T

更新日期：2015-09-01 00:00:00

abstract：:Elderly patients with valvular aortic stenosis have an increased prevalence of coronary risk factors, of coronary artery disease, and evidence of other atherosclerotic vascular diseases. Statins may reduce the progression of aortic stenosis (AS). Angina pectoris, syncope or near syncope, and congestive heart failure a...

journal_title：Cardiology in review

authors： Aronow WS

更新日期：2007-09-01 00:00:00

abstract：:Relaxin, a naturally-occurring hormone in the insulin family, was discovered to have a physiologic role in pregnancy. Named initially for its relaxing effect on the pubic ligament, relaxin receptors have since been found to be widely distributed in many organs in both males and females. Acting through multiple pathway...

journal_title：Cardiology in review

authors： Grossman J,Frishman WH

更新日期：2010-11-01 00:00:00

abstract：:Two-dimensional speckle tracking echocardiography represents a novel, simple, and reproducible technique for the estimation of left ventricular myocardial deformation (strain) and the evaluation of left ventricular twist mechanics. During the last few years, its clinical and prognostic implications in cardiomyopathies...

journal_title：Cardiology in review

authors： Zegkos T,Parcharidou D,Ntelios D,Efthimiadis G,Karvounis H

更新日期：2018-05-01 00:00:00

abstract：:Patients living with the human immunodeficiency virus (HIV) are at risk for dyslipidemia as a result of the disease itself and from certain classes of antiretroviral therapy. The protease inhibitors and non-nucleoside reverse transcription inhibitors have been associated with elevated triglycerides, total, and low-den...

journal_title：Cardiology in review

authors： Ray GM

更新日期：2009-01-01 00:00:00

abstract：:Myocardial infarction (MI) complicated by cardiogenic shock (MI-CS) is a major cause of cardiovascular morbidity and mortality. Predictors of outcomes in MI-CS include clinical, laboratory, radiologic variables, and management strategies. This article reviews the existing literature on short- and long-term predictors ...

journal_title：Cardiology in review

authors： Acharya D

更新日期：2018-09-01 00:00:00

abstract：:Numerous investigators have attempted to target the natriuretic peptide system in the treatment of heart failure since it was first described over 30 years ago. The history of neprilysin inhibition as a treatment for heart failure has been characterized by numerous setbacks. Recently, the PARADIGM-HF trial has shown f...

journal_title：Cardiology in review

authors： Bartell N,Frishman WH

更新日期：2017-11-01 00:00:00

abstract：:Intensive glycemic control significantly increases the risk of hypoglycemia in patients with diabetes mellitus. Recent data have shown that hypoglycemia may also be a marker of cardiovascular disease in these patients. We performed a systemic review and a meta-analysis to evaluate the relationship between severe hypog...

journal_title：Cardiology in review

authors： Malik AH,Yandrapalli S,Aronow WS,Jain D,Frishman WH,Panza JA,Cooper HA

更新日期：2020-09-01 00:00:00

abstract：:Radiation-induced heart disease (RIHD) is becoming an increasing concern for patients and clinicians alike as the use of radiation therapy for the treatment of certain malignancies increases, and patient mortality secondary to neoplasms of the thorax, in particular Hodgkin's lymphoma and breast cancer, decreases. The ...

journal_title：Cardiology in review

authors： Filopei J,Frishman W

更新日期：2012-07-01 00:00:00

abstract：:Evidence-based management of heart failure (HF) with preserved left ventricular ejection fraction (LVEF; HFpEF) remains a major gap in the care of patients with HF. Clinical trials directed toward the population with HFpEF have been disappointing, although renin-angiotensin-aldosterone system blockade appears to preve...

journal_title：Cardiology in review

authors： Jumean MF,Konstam MA

更新日期：2015-07-01 00:00:00

abstract：:Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

journal_title：Cardiology in review

authors： DiSalvo TG

更新日期：2015-11-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of morbidity and mortality among women in industrialized nations. Optimizing cardiovascular risk reduction is therefore of paramount importance, particularly among postmenopausal women, in whom the incidence of cardiovascular disease is highest. Accumulated data from a serie...

journal_title：Cardiology in review

authors： Mostaghel E,Waters D

更新日期：2003-01-01 00:00:00

abstract：:About 50 years ago, Norman Jefferis Holter invented a device that opened the possibility of recording heart activity over long periods of time. This invention, together with the rapid developments in electronics, has enabled a revolutionary change in the diagnosis and management of cardiac diseases. Ambulatory cardiac...

journal_title：Cardiology in review

authors： Romero I

更新日期：2013-09-01 00:00:00

abstract：:Recent articles have inquired about the quality of care for women presenting with cardiovascular disease. The Cooperative Cardiovascular Project and the National Heart Failure Project, 2 Medicare databases, provide national data to address concerns that women receive poorer quality care than men. In these databases, s...

journal_title：Cardiology in review

authors： Gold LD,Krumholz HM

更新日期：2006-07-01 00:00:00

abstract：:Interleukin 1β (IL-1β) is a proinflammatory cytokine that has been implicated in a number of rheumatologic and inflammatory conditions. The production and secretion of IL-1β from inflammatory cells is a tightly regulated process that has been extensively described and studied. In recent years, IL-1β has been associate...

journal_title：Cardiology in review

authors： McCarty S,Frishman W

更新日期：2014-07-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Endothelin is a potent vasoconstrictor substance that also can exert proliferative, inflammatory, and fibrotic changes in blood vessels and other organs. It acts on tissues in a paracrine and autocrine fashion, with local production and regulation occurring in both endothelial and nonendothelial cells. Endothelin stim...

journal_title：Cardiology in review

authors： Prasad VS,Palaniswamy C,Frishman WH

更新日期：2009-07-01 00:00:00

abstract：:The cost of medical care in the United States continues to spiral upward, partly as a result of new technological breakthroughs that promise improved length of life and quality of life for patients. But how good are these treatments in everyday practice? How do we make policies for adopting innovations that improve ou...

journal_title：Cardiology in review

authors： Heidenreich PA,Lee TT

更新日期：2000-03-01 00:00:00

abstract：:Renovascular hypertension caused by renal artery stenosis accounts for a small portion of overall hypertension but remains important as the most common potentially curable form of high blood pressure. Diagnosis depends on developing an index of suspicion for renovascular hypertension based on the history and physical ...

journal_title：Cardiology in review

authors： Klassen PS,Svetkey LP

更新日期：2000-01-01 00:00:00