Newer anticoagulants in cardiovascular disease: a systematic review of the literature.

abstract：:Cardiac rupture after a myocardial infarction is an uncommon event with devastating consequences. Although the clinical features of rupture have been described, the genetic and molecular influences on this outcome in patients are less certain. In mice, at least 17 genetic models have been developed that enhance or sup...

journal_title：Cardiology in review

authors： Sane DC,Mozingo WS,Becker RC

更新日期：2009-11-01 00:00:00

abstract：:Mechanical valve thrombosis is a life-threatening event. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. This is associated with a therapeutic dilemma. Continued anticoagulation with warfarin throughout the first trimester can result in fetopathi...

journal_title：Cardiology in review

authors： Behrendt P,Schwartzkopff B,Perings S,Gerhardt A,Zotz RB,Strauer BE

更新日期：2002-11-01 00:00:00

abstract：:This literature review examines the association of social and psychologic characteristics among women with a) the risk of developing coronary heart disease and b) prognosis and recovery after disease has become manifest. Studies of psychosocial risk factors are often conflicting. These divergent findings can result fr...

journal_title：Cardiology in review

authors： Eaker ED

更新日期：1998-05-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a progressive disorder with a poor prognosis. It is characterized by sustained elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). It is defined hemodynamically by a mean PAP over 25 mm Hg, a pulmonary arterial wedge pressure of 15 mm Hg or les...

journal_title：Cardiology in review

authors： De Marco T

更新日期：2006-11-01 00:00:00

abstract：:Reverse redistribution is a well-known pattern found when performing thallium myocardial scintigraphy, and it has been implicated as an indicator of myocardial ischemia. Much more rarely, when using technetium compounds, which do not redistribute, a similar pattern is noted after the second injection of the radiotrace...

journal_title：Cardiology in review

authors： Antonopoulos A,Galanopoulou K,Katsafados I,Siantos E

更新日期：2004-05-01 00:00:00

abstract：:Evidence-based management of heart failure (HF) with preserved left ventricular ejection fraction (LVEF; HFpEF) remains a major gap in the care of patients with HF. Clinical trials directed toward the population with HFpEF have been disappointing, although renin-angiotensin-aldosterone system blockade appears to preve...

journal_title：Cardiology in review

authors： Jumean MF,Konstam MA

更新日期：2015-07-01 00:00:00

abstract：:Radiation-induced heart disease (RIHD) is becoming an increasing concern for patients and clinicians alike as the use of radiation therapy for the treatment of certain malignancies increases, and patient mortality secondary to neoplasms of the thorax, in particular Hodgkin's lymphoma and breast cancer, decreases. The ...

journal_title：Cardiology in review

authors： Filopei J,Frishman W

更新日期：2012-07-01 00:00:00

abstract：:Left ventricular (LV) remodeling is the most common term used to describe the functional, structural, myocellular, and interstitial changes that occur in response to myocardial injury and/or chronic changes in myocardial loading conditions. Progression of LV remodeling over time in response to neurohormonal activation...

journal_title：Cardiology in review

authors： Saraon T,Katz SD

更新日期：2015-07-01 00:00:00

abstract：:Atrial fibrillation (AF), a very common cardiac arrhythmia, is a well-recognized predisposing factor for embolic stroke. While warfarin remains the cornerstone of anticoagulant treatment in patients with AF, it is often underutilized because of increased bleeding complications and frequent monitoring requirements. It ...

journal_title：Cardiology in review

authors： Gorodnitskiy A,Lucariello RJ,Aizer A,Coppola JT

更新日期：2010-09-01 00:00:00

abstract：:Differences in the overall mortality for acute infarction in women vs men have been appreciated for some time. Some of these differences are based on the age at the time of presentation of women compared with men. Excess mortality in women is most clear at the younger end of the age spectrum. More careful examination ...

journal_title：Cardiology in review

authors： Feldman T,Silver R

更新日期：2000-07-01 00:00:00

abstract：:Left ventricular noncompaction cardiomyopathy is a heart disease with relevant potential complications including heart failure, life-threatening arrhythmias, and embolic events. In order to prevent adverse outcomes, it is crucial to appropriately recognize and manage this cardiomyopathy. In this paper, we report the m...

journal_title：Cardiology in review

authors： Di Fusco SA,Lucà F,Madeo A,Massimiliano Rao C,Iorio A,Rizzo M,Dalila Luisella Delcre S,Colivicchi F,Gabrielli D,Paolo Pino G,Massimo Gulizia M

更新日期：2020-05-01 00:00:00

abstract：:We report a case of spontaneous coronary artery rupture associated with amphetamine abuse in a 31-year-old woman. The patient presented to the emergency department with sudden onset of central chest pain and a normal electrocardiogram. Cardiac enzymes were consistent with acute myocardial infarction. Drug screening wa...

journal_title：Cardiology in review

authors： Brennan K,Shurmur S,Elhendy A

更新日期：2004-09-01 00:00:00

abstract：:Endothelin is a potent vasoconstrictor substance that also can exert proliferative, inflammatory, and fibrotic changes in blood vessels and other organs. It acts on tissues in a paracrine and autocrine fashion, with local production and regulation occurring in both endothelial and nonendothelial cells. Endothelin stim...

journal_title：Cardiology in review

authors： Prasad VS,Palaniswamy C,Frishman WH

更新日期：2009-07-01 00:00:00

abstract：:Relaxin, a naturally-occurring hormone in the insulin family, was discovered to have a physiologic role in pregnancy. Named initially for its relaxing effect on the pubic ligament, relaxin receptors have since been found to be widely distributed in many organs in both males and females. Acting through multiple pathway...

journal_title：Cardiology in review

authors： Grossman J,Frishman WH

更新日期：2010-11-01 00:00:00

abstract：:There is a sexual dimorphism in blood pressure: men tend to have higher blood pressures than women with functional ovaries, whereas ovariectomy or menopause tends to abolish the sexual dimorphism and cause women to develop a "male" pattern of blood pressure. Synthetic estrogens and progestins, found in oral contracept...

journal_title：Cardiology in review

authors： Calhoun DA,Oparil S

更新日期：1998-11-01 00:00:00

abstract：:Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

journal_title：Cardiology in review

authors： DiSalvo TG

更新日期：2015-11-01 00:00:00

abstract：:The increased life expectancy of women living in industrialized countries is associated with an increase in diseases dependent or facilitated by a state of estrogen deficiency, such as cardiovascular and cerebrovascular diseases. Several studies have shown that estrogen replacement therapy reduces the occurrence of co...

journal_title：Cardiology in review

authors： Rosano GM,Fini M

更新日期：2002-01-01 00:00:00

abstract：:The complex mechanism of platelet activation creates an optimal target for pharmacological treatment in patients with acute coronary syndromes. Current antiplatelet medications that are used in addition to aspirin include the thienopyridines, clopidogrel and prasugrel, but there are several limitations to the use of t...

journal_title：Cardiology in review

authors： Nawarskas JJ,Clark SM

更新日期：2011-03-01 00:00:00

abstract：:The ever-increasing complexity of medical device therapy and installation of public electronic security systems demands vigilance in discerning interactions that may be harmful to patients during typical activities of daily living. Premature pacemaker stimulation, isolated skipped beats, or reversion to backup asynchr...

journal_title：Cardiology in review

authors： Harthorne JW

更新日期：2001-01-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a disabling chronic disorder of the pulmonary vasculature, which is characterized by increased pulmonary artery pressure as a result of increased pulmonary vascular resistance. The pathology of PAH is characterized by pulmonary vascular vasoconstriction, smooth muscle cell prol...

journal_title：Cardiology in review

authors： Anderson JR,Nawarskas JJ

更新日期：2010-05-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Established coronary artery disease has a prevalence of 7% in adult Americans, accounting for 16 million people. As morbidity and mortality rates have risen, research efforts to identify the pathophysiologic mechanisms of systolic dysfunction have risen in parallel. The current goal is to develop new therapeutic strat...

journal_title：Cardiology in review

authors： Romero J,Lupercio F,Haramati LB,Garcia MJ,Lucariello RJ

更新日期：2014-09-01 00:00:00

abstract：:Arsenic is a ubiquitously dispersed metalloid that has been implicated as the cause of various adverse health effects. Human exposure to arsenic primarily occurs through contaminated drinking water and dietary intake of rice and grains, posing a great public health risk to millions of people worldwide. High levels of ...

journal_title：Cardiology in review

authors： Kononenko M,Frishman WH

更新日期：2020-09-15 00:00:00

abstract：:Severe acute respiratory coronavirus-2 (SARS-CoV-2) is responsible for one of the greatest public health challenges of our lifetime, the coronavirus disease 2019 (COVID-19) pandemic. Because of the complicated postinfection sequelae and grave consequences, the search for effective therapies has become a worldwide prio...

journal_title：Cardiology in review

authors： Mehta M,Shyh GI

更新日期：2020-11-01 00:00:00

abstract：:A decision-tree analysis was used to estimate the average cost per patient using the direct thrombin inhibitor argatroban for early treatment (<48 hours after thrombocytopenia onset) compared with delayed treatment (> or =48 hours after thrombocytopenia onset) of immune-mediated heparin-induced thrombocytopenia (HIT) ...

journal_title：Cardiology in review

authors： Arnold RJ,Kim R,Tang B

更新日期：2006-01-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) has become a mainstay therapy to improve clinical outcomes of patients with left ventricular systolic dysfunction and a wide QRS complex, in addition to guideline-directed medical therapy. As clinical experience with CRT continues to expand, the device and lead design, along wit...

journal_title：Cardiology in review

authors： Ng CY,Heist EK

更新日期：2017-01-01 00:00:00

abstract：:There is growing evidence that inflammatory processes may be involved in the development of atherosclerosis and its complications. Viral and bacterial pathogens have been implicated as possible causative factors in the pathogenesis of coronary artery disease and postangioplasty restenosis. Antibiotic trials have been ...

journal_title：Cardiology in review

authors： Frishman WH,Ismail AA

更新日期：2002-07-01 00:00:00

abstract：:Patients presenting to the Emergency Department with chest pain are common and often present diagnostic difficulties. Because of the limitations of the initial evaluation, the majority of patients are admitted, although many are later found to have noncardiac causes for their symptoms. Recognition of these limitations...

journal_title：Cardiology in review

authors： Kontos MC

更新日期：2001-09-01 00:00:00

abstract：:Recent articles have inquired about the quality of care for women presenting with cardiovascular disease. The Cooperative Cardiovascular Project and the National Heart Failure Project, 2 Medicare databases, provide national data to address concerns that women receive poorer quality care than men. In these databases, s...

journal_title：Cardiology in review

authors： Gold LD,Krumholz HM

更新日期：2006-07-01 00:00:00

abstract：:Atrial fibrillation (AF) is an independent risk factor for ischemic stroke occurrence, severity, recurrence, and mortality. Anticoagulation therapy for the prevention of thromboembolism is critical in patients with AF who are at risk of stroke. Warfarin has been an efficacious anticoagulant for this purpose, but its u...

journal_title：Cardiology in review

authors： Lam S

更新日期：2013-07-01 00:00:00