What a physician needs to know about cost-effectiveness.

abstract：:Endothelin is a potent vasoconstrictor substance that also can exert proliferative, inflammatory, and fibrotic changes in blood vessels and other organs. It acts on tissues in a paracrine and autocrine fashion, with local production and regulation occurring in both endothelial and nonendothelial cells. Endothelin stim...

journal_title：Cardiology in review

authors： Prasad VS,Palaniswamy C,Frishman WH

更新日期：2009-07-01 00:00:00

abstract：:Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of ...

journal_title：Cardiology in review

authors： Khera S,Jacobson JT

更新日期：2016-07-01 00:00:00

abstract：:Established coronary artery disease has a prevalence of 7% in adult Americans, accounting for 16 million people. As morbidity and mortality rates have risen, research efforts to identify the pathophysiologic mechanisms of systolic dysfunction have risen in parallel. The current goal is to develop new therapeutic strat...

journal_title：Cardiology in review

authors： Romero J,Lupercio F,Haramati LB,Garcia MJ,Lucariello RJ

更新日期：2014-09-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affect...

journal_title：Cardiology in review

authors： Adamczak DM,Oko-Sarnowska Z

更新日期：2018-05-01 00:00:00

abstract：:Severe acute respiratory coronavirus-2 (SARS-CoV-2) is responsible for one of the greatest public health challenges of our lifetime, the coronavirus disease 2019 (COVID-19) pandemic. Because of the complicated postinfection sequelae and grave consequences, the search for effective therapies has become a worldwide prio...

journal_title：Cardiology in review

authors： Mehta M,Shyh GI

更新日期：2020-11-01 00:00:00

abstract：:It has been shown in rodents and newborn babies that brown adipose tissue (BAT) plays an important role in the generation of heat for maintenance of core body temperature. BAT is responsible for the process of adaptive thermogenesis, which involves heat generation in response to a drop in the environment's temperature...

journal_title：Cardiology in review

authors： Mund RA,Frishman WH

更新日期：2013-11-01 00:00:00

abstract：:Automatic implantable cardioverter-defibrillators (AICDs) were implanted in 378 men and 95 women, mean age 69 +/- 12 years. At 3.6-year follow up, survival was 76% in patients who had an AICD because of cardiac arrest as a result of ventricular fibrillation or ventricular tachycardia not resulting from a transient or ...

journal_title：Cardiology in review

authors： Aronow WS,Sorbera C,Chagarlamudi A,Tabandeh H,Gupta S,Cohen M

更新日期：2005-01-01 00:00:00

abstract：:Arsenic is a ubiquitously dispersed metalloid that has been implicated as the cause of various adverse health effects. Human exposure to arsenic primarily occurs through contaminated drinking water and dietary intake of rice and grains, posing a great public health risk to millions of people worldwide. High levels of ...

journal_title：Cardiology in review

authors： Kononenko M,Frishman WH

更新日期：2020-09-15 00:00:00

abstract：:Evidence-based management of heart failure (HF) with preserved left ventricular ejection fraction (LVEF; HFpEF) remains a major gap in the care of patients with HF. Clinical trials directed toward the population with HFpEF have been disappointing, although renin-angiotensin-aldosterone system blockade appears to preve...

journal_title：Cardiology in review

authors： Jumean MF,Konstam MA

更新日期：2015-07-01 00:00:00

abstract：:Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatmen...

journal_title：Cardiology in review

authors： Okyay K,Cemri M,Boyac B,Yalcn R,Cengel A

更新日期：2005-11-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a progressive disorder with a poor prognosis. It is characterized by sustained elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). It is defined hemodynamically by a mean PAP over 25 mm Hg, a pulmonary arterial wedge pressure of 15 mm Hg or les...

journal_title：Cardiology in review

authors： De Marco T

更新日期：2006-11-01 00:00:00

abstract：:The effect of an ongoing educational program on the use of cardiovascular drugs in patients with coronary artery disease without contraindications to these drugs seen in an academic cardiology clinic was assessed in 100 patients seen during the 6-month period prior to the educational program and in 200 patients seen 9...

journal_title：Cardiology in review

authors： Nayak D,Aronow WS

更新日期：2005-03-01 00:00:00

abstract：:Magnesium, the fourth most abundant cation in the human body, is involved in several essential physiological, biochemical, and cellular processes regulating cardiovascular function. It plays a critical role in modulating vascular smooth muscle tone, endothelial cell function, and myocardial excitability and is thus ce...

journal_title：Cardiology in review

authors： Kolte D,Vijayaraghavan K,Khera S,Sica DA,Frishman WH

更新日期：2014-07-01 00:00:00

abstract：:Inflammatory cardiomyopathy is a broad term encompassing any disease leading to myocardial inflammation with associated cardiac dysfunction. While endomyocardial biopsy remains the gold standard for diagnosis, non-invasive imaging techniques, such as cardiac magnetic resonance imaging and positron emission tomography,...

journal_title：Cardiology in review

authors： Li B,Lento PA,Pan S

更新日期：2020-11-02 00:00:00

abstract：:The literature on the relationship between work-related psychosocial factors and the development of ischemic heart disease (IHD) was systematically reviewed: 33 articles presented 51 analyses of studies involving male participants, 18 analyses involving female participants, and 8 analyses with both genders. Twenty of ...

journal_title：Cardiology in review

authors： Eller NH,Netterstrøm B,Gyntelberg F,Kristensen TS,Nielsen F,Steptoe A,Theorell T

更新日期：2009-03-01 00:00:00

abstract：:Valvular endocarditis after percutaneous coronary intervention is unusual. We report a new case of mitral valve endocarditis after stent implantation to a saphenous vein graft. ...

journal_title：Cardiology in review

authors： Palmer ND,Ramsdale DR

更新日期：2005-05-01 00:00:00

abstract：:Myocarditis represents a heterogeneous final common pathway for myocardial inflammation of diverse etiologies and accounts for up to one-third of cases of dilated cardiomyopathy. The pathophysiology of viral myocarditis can be disaggregated into the effects of direct viral mediated injury, triggered acute and chronic ...

journal_title：Cardiology in review

authors： Ellis CR,Di Salvo T

更新日期：2007-07-01 00:00:00

abstract：:The human intestine contains the largest and most diverse ecosystem of microbes. The main function of the intestinal bacterial flora is to limit the growth of potentially pathogenic microorganisms. However, the intestinal microbiota is increasingly emerging as a risk factor for the development of cardiovascular diseas...

journal_title：Cardiology in review

authors： Anselmi G,Gagliardi L,Egidi G,Leone S,Gasbarrini A,Miggiano GAD,Galiuto L

更新日期：2020-06-18 00:00:00

abstract：:The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricul...

journal_title：Cardiology in review

authors： Levine A,Gass A

更新日期：2019-11-01 00:00:00

abstract：:Atrial fibrillation (AF) is a common cardiac arrhythmia with significant morbidity and public health cost. Because of limitations of efficacy and safety of conventional antiarrhythmic agents, alternative therapies for AF are needed. The potential antiarrhythmic properties of lipid-altering therapy, including the 3-hyd...

journal_title：Cardiology in review

authors： Bachmann JM,Majmudar M,Tompkins C,Blumenthal RS,Marine JE

更新日期：2008-07-01 00:00:00

abstract：:About 50 years ago, Norman Jefferis Holter invented a device that opened the possibility of recording heart activity over long periods of time. This invention, together with the rapid developments in electronics, has enabled a revolutionary change in the diagnosis and management of cardiac diseases. Ambulatory cardiac...

journal_title：Cardiology in review

authors： Romero I

更新日期：2013-09-01 00:00:00

abstract：:Differences in the overall mortality for acute infarction in women vs men have been appreciated for some time. Some of these differences are based on the age at the time of presentation of women compared with men. Excess mortality in women is most clear at the younger end of the age spectrum. More careful examination ...

journal_title：Cardiology in review

authors： Feldman T,Silver R

更新日期：2000-07-01 00:00:00

abstract：:Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

journal_title：Cardiology in review

authors： DiSalvo TG

更新日期：2015-11-01 00:00:00

abstract：:Two-dimensional speckle tracking echocardiography represents a novel, simple, and reproducible technique for the estimation of left ventricular myocardial deformation (strain) and the evaluation of left ventricular twist mechanics. During the last few years, its clinical and prognostic implications in cardiomyopathies...

journal_title：Cardiology in review

authors： Zegkos T,Parcharidou D,Ntelios D,Efthimiadis G,Karvounis H

更新日期：2018-05-01 00:00:00

abstract：:Intensive glycemic control significantly increases the risk of hypoglycemia in patients with diabetes mellitus. Recent data have shown that hypoglycemia may also be a marker of cardiovascular disease in these patients. We performed a systemic review and a meta-analysis to evaluate the relationship between severe hypog...

journal_title：Cardiology in review

authors： Malik AH,Yandrapalli S,Aronow WS,Jain D,Frishman WH,Panza JA,Cooper HA

更新日期：2020-09-01 00:00:00

abstract：:Patients presenting to the Emergency Department with chest pain are common and often present diagnostic difficulties. Because of the limitations of the initial evaluation, the majority of patients are admitted, although many are later found to have noncardiac causes for their symptoms. Recognition of these limitations...

journal_title：Cardiology in review

authors： Kontos MC

更新日期：2001-09-01 00:00:00

abstract：:The differentiation of left ventricular pseudoaneurysm from true aneurysm is sometimes difficult. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is clinically impo...

journal_title：Cardiology in review

authors： Cho MN,Mehta SK,Matulevicius S,Weinstein D,Wait MA,McGuire DK

更新日期：2006-11-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Stress radionuclide myocardial perfusion imaging is a commonly used modality to evaluate patients with known or suspected coronary artery disease. The dual isotope rest thallium-201/stress technetium-99m sestamibi gated single-photon emission computed tomography protocol has gained increasing popularity for these appl...

journal_title：Cardiology in review

authors： Hachamovitch R

更新日期：1999-03-01 00:00:00

abstract：:Mitral regurgitation (MR) is the most common cardiac valvular disease in the United States. Approximately 4 million people have severe MR and roughly 250,000 new diagnoses of MR are made each year. Mitral valve surgery is the only treatment that prevents progression of heart failure and provides sustained symptomatic ...

journal_title：Cardiology in review

authors： Doshi JV,Agrawal S,Garg J,Paudel R,Palaniswamy C,Doshi TV,Gotsis W,Frishman WH

更新日期：2014-11-01 00:00:00