Role of infection in atherosclerosis and coronary artery disease: a new therapeutic target?

abstract：:The presence of pulmonary arterial hypertension (PAH) in pregnancy is rare and signifies a high-risk pregnancy. Although the majority of mothers have knowledge of their condition before pregnancy, approximately one-third of patients are diagnosed during pregnancy. Termination of pregnancy should be discussed, and is o...

journal_title：Cardiology in review

authors： Martínez MV,Rutherford JD

更新日期：2013-07-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a disabling chronic disorder of the pulmonary vasculature, which is characterized by increased pulmonary artery pressure as a result of increased pulmonary vascular resistance. The pathology of PAH is characterized by pulmonary vascular vasoconstriction, smooth muscle cell prol...

journal_title：Cardiology in review

authors： Anderson JR,Nawarskas JJ

更新日期：2010-05-01 00:00:00

abstract：:Underlying causes, risk factors, and precipitating causes of heart failure (HF) should be treated. Drugs known to precipitate or aggravate HF such as nonsteroidal antiinflammatory drugs should be stopped. Patients with HF and a low left ventricular ejection fraction (systolic heart failure) or normal ejection fraction...

journal_title：Cardiology in review

authors： Aronow WS

更新日期：2006-05-01 00:00:00

abstract：:Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatmen...

journal_title：Cardiology in review

authors： Okyay K,Cemri M,Boyac B,Yalcn R,Cengel A

更新日期：2005-11-01 00:00:00

abstract：:Differences in the overall mortality for acute infarction in women vs men have been appreciated for some time. Some of these differences are based on the age at the time of presentation of women compared with men. Excess mortality in women is most clear at the younger end of the age spectrum. More careful examination ...

journal_title：Cardiology in review

authors： Feldman T,Silver R

更新日期：2000-07-01 00:00:00

abstract：:Acute pericarditis (AP) is basically a clinical diagnosis. Although specific electrocardiographic (ECG) manifestations may indeed point to its diagnosis, sole reliance on such findings in isolation of the clinical setting, however, is often the common pitfall that could lead to a misguided diagnosis. We briefly review...

journal_title：Cardiology in review

authors： Ariyarajah V,Spodick DH

更新日期：2007-01-01 00:00:00

abstract：:Hypertrophic cardiomyopathy (HCM) is a heart disease characterized by hypertrophy of the left ventricular myocardium and is most often caused by mutations in sarcomere genes. The structural and functional abnormalities are not explained by flow-limiting coronary artery disease or loading conditions. The disease affect...

journal_title：Cardiology in review

authors： Adamczak DM,Oko-Sarnowska Z

更新日期：2018-05-01 00:00:00

abstract：:As direct oral anticoagulants (DOACs) have demonstrated favorable efficacy and safety outcomes compared with vitamin K antagonists for the treatment and prevention of venous thromboembolism and the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, their role in the management...

journal_title：Cardiology in review

authors： Finks SW,Dobesh PP,Trujillo TC,Crossley GH

更新日期：2018-09-01 00:00:00

abstract：:Epigenetic regulatory mechanisms play key roles in cardiac development, differentiation, homeostasis, response to stress and injury, and disease. Human heart failure (HF) epigenetic regulatory mechanisms have not been deciphered to date. This 2-part review distills the rapidly evolving research focused on human HF epi...

journal_title：Cardiology in review

authors： DiSalvo TG

更新日期：2015-11-01 00:00:00

abstract：:Atrial fibrillation (AF), a very common cardiac arrhythmia, is a well-recognized predisposing factor for embolic stroke. While warfarin remains the cornerstone of anticoagulant treatment in patients with AF, it is often underutilized because of increased bleeding complications and frequent monitoring requirements. It ...

journal_title：Cardiology in review

authors： Gorodnitskiy A,Lucariello RJ,Aizer A,Coppola JT

更新日期：2010-09-01 00:00:00

abstract：:Abdominal aortic aneurysm is a multifactorial disease with genetic risk factors and an immunologic component. Immune cells, including macrophages, neutrophils, mast cells, B- and T- lymphocytes, along with vascular smooth muscle cells and adventitial fibroblasts, produce cytokines and enzymes, promoting an inflammator...

journal_title：Cardiology in review

authors： Rizas KD,Ippagunta N,Tilson MD 3rd

更新日期：2009-09-01 00:00:00

abstract：:Cardiac rupture after a myocardial infarction is an uncommon event with devastating consequences. Although the clinical features of rupture have been described, the genetic and molecular influences on this outcome in patients are less certain. In mice, at least 17 genetic models have been developed that enhance or sup...

journal_title：Cardiology in review

authors： Sane DC,Mozingo WS,Becker RC

更新日期：2009-11-01 00:00:00

abstract：:Acute decompensated heart failure (ADHF) is a common syndrome with diverse etiologies and precipitating factors, which is associated with significant morbidity and mortality. Tremendous resources are used in treating this syndrome, with few prospectively designed clinical trials to guide therapy. Patients suffering fr...

journal_title：Cardiology in review

authors： Sanchez CE,Richards DR

更新日期：2011-05-01 00:00:00

abstract：:Myocarditis represents a heterogeneous final common pathway for myocardial inflammation of diverse etiologies and accounts for up to one-third of cases of dilated cardiomyopathy. The pathophysiology of viral myocarditis can be disaggregated into the effects of direct viral mediated injury, triggered acute and chronic ...

journal_title：Cardiology in review

authors： Ellis CR,Di Salvo T

更新日期：2007-07-01 00:00:00

abstract：:The human intestine contains the largest and most diverse ecosystem of microbes. The main function of the intestinal bacterial flora is to limit the growth of potentially pathogenic microorganisms. However, the intestinal microbiota is increasingly emerging as a risk factor for the development of cardiovascular diseas...

journal_title：Cardiology in review

authors： Anselmi G,Gagliardi L,Egidi G,Leone S,Gasbarrini A,Miggiano GAD,Galiuto L

更新日期：2020-06-18 00:00:00

abstract：:Cardiac computed tomographic angiography (CCTA) has evolved at an unprecedented pace over the past decade, during which time it has proven to be an accurate and effective tool for imaging of the heart in a growing list of clinical applications. However, the rapid growth in the use of CT imaging in general has prompted...

journal_title：Cardiology in review

authors： Entrikin DW,Leipsic JA,Carr JJ

更新日期：2011-07-01 00:00:00

abstract：:Cardiovascular magnetic resonance using late gadolinium enhancement (LGE) provides a unique opportunity to assess myocardial tissue in vivo. LGE enables tissue characterization in ischemic and nonischemic cardiomyopathies and other cardiac diseases. LGE is associated with adverse clinical outcomes across a range of di...

journal_title：Cardiology in review

authors： Panovsky R,Pleva M,Feitova V,Kruzliak P,Meluzin J,Kincl V

更新日期：2014-05-01 00:00:00

abstract：:Elderly patients with valvular aortic stenosis have an increased prevalence of coronary risk factors, of coronary artery disease, and evidence of other atherosclerotic vascular diseases. Statins may reduce the progression of aortic stenosis (AS). Angina pectoris, syncope or near syncope, and congestive heart failure a...

journal_title：Cardiology in review

authors： Aronow WS

更新日期：2007-09-01 00:00:00

abstract：:Computed tomography is an established tool in the assessment of cardiac anatomy and function. As demonstrated by single photon emission computed tomography, positron emission tomography, and magnetic resonance, the noninvasive evaluation of coronary hemodynamics is an important step in guiding clinical management. Nev...

journal_title：Cardiology in review

authors： Lempel M,Frishman WH

更新日期：2019-07-01 00:00:00

abstract：:There is a sexual dimorphism in blood pressure: men tend to have higher blood pressures than women with functional ovaries, whereas ovariectomy or menopause tends to abolish the sexual dimorphism and cause women to develop a "male" pattern of blood pressure. Synthetic estrogens and progestins, found in oral contracept...

journal_title：Cardiology in review

authors： Calhoun DA,Oparil S

更新日期：1998-11-01 00:00:00

abstract：:An estimated 400,000 coronary artery bypass graft operations are performed annually in the United States. Saphenous vein grafts are the most commonly used conduits; however, graft failure is common. In contrast, left internal mammary artery grafts have more favorable long-term patency rates. Guidelines recommend aggre...

journal_title：Cardiology in review

authors： Collins D,Goldberg S

更新日期：2020-01-01 00:00:00

abstract：:Mechanical valve thrombosis is a life-threatening event. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. This is associated with a therapeutic dilemma. Continued anticoagulation with warfarin throughout the first trimester can result in fetopathi...

journal_title：Cardiology in review

authors： Behrendt P,Schwartzkopff B,Perings S,Gerhardt A,Zotz RB,Strauer BE

更新日期：2002-11-01 00:00:00

abstract：:Established coronary artery disease has a prevalence of 7% in adult Americans, accounting for 16 million people. As morbidity and mortality rates have risen, research efforts to identify the pathophysiologic mechanisms of systolic dysfunction have risen in parallel. The current goal is to develop new therapeutic strat...

journal_title：Cardiology in review

authors： Romero J,Lupercio F,Haramati LB,Garcia MJ,Lucariello RJ

更新日期：2014-09-01 00:00:00

abstract：:Despite recent advances in the management of chronic heart failure (CHF), the prognosis of many of these patients remains dire. The need for an accurate prognosis in these patients has led to the identification of several indicators purported to represent the impact of the disease. Such indicators often are obtained a...

journal_title：Cardiology in review

authors： Jorge Alves A,Ribeiro F,Sagiv M,Eynon N,Yamin C,Sagiv M,Oliveira J

更新日期：2010-07-01 00:00:00

abstract：:Patients living with the human immunodeficiency virus (HIV) are at risk for dyslipidemia as a result of the disease itself and from certain classes of antiretroviral therapy. The protease inhibitors and non-nucleoside reverse transcription inhibitors have been associated with elevated triglycerides, total, and low-den...

journal_title：Cardiology in review

authors： Ray GM

更新日期：2009-01-01 00:00:00

abstract：:Two-dimensional speckle tracking echocardiography represents a novel, simple, and reproducible technique for the estimation of left ventricular myocardial deformation (strain) and the evaluation of left ventricular twist mechanics. During the last few years, its clinical and prognostic implications in cardiomyopathies...

journal_title：Cardiology in review

authors： Zegkos T,Parcharidou D,Ntelios D,Efthimiadis G,Karvounis H

更新日期：2018-05-01 00:00:00

abstract：:Short QT syndrome is a rare inherited autosomal dominant cardiac channelopathy associated with malignant ventricular and atrial arrhythmias. A shortened corrected QT interval is a marker for risk of malignant arrhythmias, which are secondary to increased transmural dispersion of repolarization. The underlying gain of ...

journal_title：Cardiology in review

authors： Khera S,Jacobson JT

更新日期：2016-07-01 00:00:00

abstract：:We investigated the accuracy of computed tomographic measurements of main pulmonary artery diameter (MPAD) and of MPAD/ascending aorta diameter (AAD) in predicting moderate or severe pulmonary hypertension in 190 patients with acute pulmonary embolism. A pulmonary artery systolic pressure of > or = 50 mm Hg measured b...

journal_title：Cardiology in review

authors： Sanal S,Aronow WS,Ravipati G,Maguire GP,Belkin RN,Lehrman SG

更新日期：2006-09-01 00:00:00

abstract：:Valvular endocarditis after percutaneous coronary intervention is unusual. We report a new case of mitral valve endocarditis after stent implantation to a saphenous vein graft. ...

journal_title：Cardiology in review

authors： Palmer ND,Ramsdale DR

更新日期：2005-05-01 00:00:00

abstract：:Vitamin K antagonists (VKAs) such as warfarin have traditionally been the major therapeutic option for anticoagulation in clinical practice. VKAs are effective and extensively recommended for the prevention of venous and arterial thromboembolism in cardiovascular disease. Despite its effectiveness, warfarin is limited...

journal_title：Cardiology in review

authors： Maan A,Padmanabhan R,Shaikh AY,Mansour M,Ruskin JN,Heist EK

更新日期：2012-09-01 00:00:00