Pharmacotherapeutic management of pulmonary arterial hypertension.

abstract：:We investigated the accuracy of computed tomographic measurements of main pulmonary artery diameter (MPAD) and of MPAD/ascending aorta diameter (AAD) in predicting moderate or severe pulmonary hypertension in 190 patients with acute pulmonary embolism. A pulmonary artery systolic pressure of > or = 50 mm Hg measured b...

journal_title：Cardiology in review

authors： Sanal S,Aronow WS,Ravipati G,Maguire GP,Belkin RN,Lehrman SG

更新日期：2006-09-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a progressive disorder with a poor prognosis. It is characterized by sustained elevation of pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR). It is defined hemodynamically by a mean PAP over 25 mm Hg, a pulmonary arterial wedge pressure of 15 mm Hg or les...

journal_title：Cardiology in review

authors： De Marco T

更新日期：2006-11-01 00:00:00

abstract：:Underlying causes, risk factors, and precipitating causes of heart failure (HF) should be treated. Drugs known to precipitate or aggravate HF such as nonsteroidal antiinflammatory drugs should be stopped. Patients with HF and a low left ventricular ejection fraction (systolic heart failure) or normal ejection fraction...

journal_title：Cardiology in review

authors： Aronow WS

更新日期：2006-05-01 00:00:00

abstract：:Arsenic is a ubiquitously dispersed metalloid that has been implicated as the cause of various adverse health effects. Human exposure to arsenic primarily occurs through contaminated drinking water and dietary intake of rice and grains, posing a great public health risk to millions of people worldwide. High levels of ...

journal_title：Cardiology in review

authors： Kononenko M,Frishman WH

更新日期：2020-09-15 00:00:00

abstract：:Mechanical valve thrombosis is a life-threatening event. Pregnancy is associated with a hypercoagulable state that further emphasizes the importance of adequate anticoagulation. This is associated with a therapeutic dilemma. Continued anticoagulation with warfarin throughout the first trimester can result in fetopathi...

journal_title：Cardiology in review

authors： Behrendt P,Schwartzkopff B,Perings S,Gerhardt A,Zotz RB,Strauer BE

更新日期：2002-11-01 00:00:00

abstract：:Eisenmenger syndrome is characterized by elevated pulmonary vascular resistance and right-to-left shunting of blood through a systemic to pulmonary circulation connection. Treatment requires either lung transplantation with intracardiac repair or heart-lung transplantation. There are inadequate data regarding treatmen...

journal_title：Cardiology in review

authors： Okyay K,Cemri M,Boyac B,Yalcn R,Cengel A

更新日期：2005-11-01 00:00:00

abstract：:Vitamin K antagonists (VKAs) such as warfarin have traditionally been the major therapeutic option for anticoagulation in clinical practice. VKAs are effective and extensively recommended for the prevention of venous and arterial thromboembolism in cardiovascular disease. Despite its effectiveness, warfarin is limited...

journal_title：Cardiology in review

authors： Maan A,Padmanabhan R,Shaikh AY,Mansour M,Ruskin JN,Heist EK

更新日期：2012-09-01 00:00:00

abstract：:Evacetrapib is a cholesteryl ester transfer protein (CETP) inhibitor that has been recently studied as a cholesterol modifying agent to reduce cardiovascular risk and mortality in high risk cardiovascular disease patients. Evacetrapib acts to decrease lipid exchange through CETP inhibition. CETP acts to transfer chole...

journal_title：Cardiology in review

authors： Eyvazian VA,Frishman WH

更新日期：2017-03-01 00:00:00

abstract：:Care of pregnant patients with congenital heart disease requires understanding of the specific congenital defect, the nature of previous surgical correction, and the residua and sequelae. General risks and principles can be adduced in management decisions. In addition, lesion- and patient-specific details are importan...

journal_title：Cardiology in review

authors： Colman JM,Sermer M,Seaward PG,Siu SC

更新日期：2000-05-01 00:00:00

abstract：:Saphenous vein graft (SVG) disease after coronary artery bypass grafting (CABG) occurs in three phases: thrombosis, intimal hyperplasia, and atherosclerosis. Within the first month, thrombosis plays a major role. From month 1 to month 12, intimal hyperplasia occurs. Beyond 12 months, atherosclerosis becomes the primar...

journal_title：Cardiology in review

authors： Kim FY,Marhefka G,Ruggiero NJ,Adams S,Whellan DJ

更新日期：2013-03-01 00:00:00

abstract：:The effect of an ongoing educational program on the use of cardiovascular drugs in patients with coronary artery disease without contraindications to these drugs seen in an academic cardiology clinic was assessed in 100 patients seen during the 6-month period prior to the educational program and in 200 patients seen 9...

journal_title：Cardiology in review

authors： Nayak D,Aronow WS

更新日期：2005-03-01 00:00:00

abstract：:The introduction of new medicines to treat pulmonary vascular disease has renewed interest in the management of children with idiopathic pulmonary arterial hypertension. We now have a practical classification of pulmonary hypertension, improved diagnostic techniques, and internationally recognized diagnostic and manag...

journal_title：Cardiology in review

authors： Haworth SG

更新日期：2010-03-01 00:00:00

abstract：:The presence of pulmonary arterial hypertension (PAH) in pregnancy is rare and signifies a high-risk pregnancy. Although the majority of mothers have knowledge of their condition before pregnancy, approximately one-third of patients are diagnosed during pregnancy. Termination of pregnancy should be discussed, and is o...

journal_title：Cardiology in review

authors： Martínez MV,Rutherford JD

更新日期：2013-07-01 00:00:00

abstract：:Pulmonary artery hypertension (PAH) is a sequela of a number of disparate diseases, often with a fatal consequence. Endothelial dysfunction is considered to be an early event during the development of PAH. Impaired availability of bioactive nitric oxide (NO) is a key underlying feature in most forms of clinical and ex...

journal_title：Cardiology in review

authors： Mathew R,Huang J,Gewitz MH

更新日期：2007-05-01 00:00:00

abstract：:Patients living with the human immunodeficiency virus (HIV) are at risk for dyslipidemia as a result of the disease itself and from certain classes of antiretroviral therapy. The protease inhibitors and non-nucleoside reverse transcription inhibitors have been associated with elevated triglycerides, total, and low-den...

journal_title：Cardiology in review

authors： Ray GM

更新日期：2009-01-01 00:00:00

abstract：:The human intestine contains the largest and most diverse ecosystem of microbes. The main function of the intestinal bacterial flora is to limit the growth of potentially pathogenic microorganisms. However, the intestinal microbiota is increasingly emerging as a risk factor for the development of cardiovascular diseas...

journal_title：Cardiology in review

authors： Anselmi G,Gagliardi L,Egidi G,Leone S,Gasbarrini A,Miggiano GAD,Galiuto L

更新日期：2020-06-18 00:00:00

abstract：:Severe acute respiratory coronavirus-2 (SARS-CoV-2) is responsible for one of the greatest public health challenges of our lifetime, the coronavirus disease 2019 (COVID-19) pandemic. Because of the complicated postinfection sequelae and grave consequences, the search for effective therapies has become a worldwide prio...

journal_title：Cardiology in review

authors： Mehta M,Shyh GI

更新日期：2020-11-01 00:00:00

abstract：:Cryptogenic stroke (CS) accounts for 20% to 40% of ischemic strokes. CS is defined as a cortical infarct suggestive of an embolic stroke with no identifiable cardiac etiology, large vessel occlusive disease, or small vessel lacunar stroke. The likely etiologies for CS are patent foramen ovale (PFO) and paroxysmal atri...

journal_title：Cardiology in review

authors： Marks SJ,Khera S

更新日期：2016-07-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of morbidity and mortality among women in industrialized nations. Optimizing cardiovascular risk reduction is therefore of paramount importance, particularly among postmenopausal women, in whom the incidence of cardiovascular disease is highest. Accumulated data from a serie...

journal_title：Cardiology in review

authors： Mostaghel E,Waters D

更新日期：2003-01-01 00:00:00

abstract：:Cardiac computed tomographic angiography (CCTA) has evolved at an unprecedented pace over the past decade, during which time it has proven to be an accurate and effective tool for imaging of the heart in a growing list of clinical applications. However, the rapid growth in the use of CT imaging in general has prompted...

journal_title：Cardiology in review

authors： Entrikin DW,Leipsic JA,Carr JJ

更新日期：2011-07-01 00:00:00

abstract：:Cholesterol metabolism and transport has been a major focus in cardiovascular disease risk modification over the past several decades. Hydroxymethylglutaryl-CoA reductase inhibitors (statins) have been the most commonly used agents, with the greatest benefit in reducing both the primary and secondary risks of cardiova...

journal_title：Cardiology in review

authors： Grabie M,Tai CH,Frishman WH

更新日期：2019-09-01 00:00:00

abstract：:The ever-increasing complexity of medical device therapy and installation of public electronic security systems demands vigilance in discerning interactions that may be harmful to patients during typical activities of daily living. Premature pacemaker stimulation, isolated skipped beats, or reversion to backup asynchr...

journal_title：Cardiology in review

authors： Harthorne JW

更新日期：2001-01-01 00:00:00

abstract：:The differentiation of left ventricular pseudoaneurysm from true aneurysm is sometimes difficult. Given the propensity for pseudoaneurysms to rupture leading to cardiac tamponade, shock, and death, compared with a more benign natural history for true aneurysms, accurate diagnosis of these conditions is clinically impo...

journal_title：Cardiology in review

authors： Cho MN,Mehta SK,Matulevicius S,Weinstein D,Wait MA,McGuire DK

更新日期：2006-11-01 00:00:00

abstract：:Loop diuretics are central to the management of fluid overload in acute decompensated heart failure. However, a variance in the response to loop diuretics can alter a patient's clinical course and has an adverse effect on clinical outcomes. Thus, a diminished response to loop diuretics is an important clinical issue. ...

journal_title：Cardiology in review

authors： Bowman BN,Nawarskas JJ,Anderson JR

更新日期：2016-09-01 00:00:00

abstract：:About 50 years ago, Norman Jefferis Holter invented a device that opened the possibility of recording heart activity over long periods of time. This invention, together with the rapid developments in electronics, has enabled a revolutionary change in the diagnosis and management of cardiac diseases. Ambulatory cardiac...

journal_title：Cardiology in review

authors： Romero I

更新日期：2013-09-01 00:00:00

abstract：:Myocarditis represents a heterogeneous final common pathway for myocardial inflammation of diverse etiologies and accounts for up to one-third of cases of dilated cardiomyopathy. The pathophysiology of viral myocarditis can be disaggregated into the effects of direct viral mediated injury, triggered acute and chronic ...

journal_title：Cardiology in review

authors： Ellis CR,Di Salvo T

更新日期：2007-07-01 00:00:00

abstract：:An estimated 400,000 coronary artery bypass graft operations are performed annually in the United States. Saphenous vein grafts are the most commonly used conduits; however, graft failure is common. In contrast, left internal mammary artery grafts have more favorable long-term patency rates. Guidelines recommend aggre...

journal_title：Cardiology in review

authors： Collins D,Goldberg S

更新日期：2020-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is a common cardiac arrhythmia with significant morbidity and public health cost. Because of limitations of efficacy and safety of conventional antiarrhythmic agents, alternative therapies for AF are needed. The potential antiarrhythmic properties of lipid-altering therapy, including the 3-hyd...

journal_title：Cardiology in review

authors： Bachmann JM,Majmudar M,Tompkins C,Blumenthal RS,Marine JE

更新日期：2008-07-01 00:00:00

abstract：:Atherosclerosis develops and rapidly progresses in saphenous veins grafts after coronary bypass surgery. In contrast to native coronary artery, percutaneous revascularization does not impede the progression of saphenous vein atherosclerosis and saphenous vein graft failure commonly ensues. The protracted patency of ar...

journal_title：Cardiology in review

authors： Motwani A,Ayinapudi K,Singh T,Maini R,Hendel R,Le Jemtel TH

更新日期：2020-09-01 00:00:00

abstract：:The field of durable left ventricular assist devices has advanced dramatically since its introduction into the clinical realm. From the first-generation pulsatile HeartMate XVE device to the second-generation continuous axial flow HeartMate-2 to the current third-generation centrifugal flow devices, the left ventricul...

journal_title：Cardiology in review

authors： Levine A,Gass A

更新日期：2019-11-01 00:00:00