Impact of nickel oral hyposensitization on quality of life in systemic nickel allergy syndrome.

Abstract:

:Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to assess changes of HRQoL after 1 year of NiOHT; (c) to evaluate psychological status of patients. SNAS patients completed the Short-Form 36-Item Health Survey and Psychological General Well-Being Index before and 1 week after the end of NiOHT. Moreover, psychological state was assessed with the Minnesota Multiphasic Personality Inventory (MMPI-2). A total of 52 patients self-reported pre- and post-treatment questionnaires. HRQoL was poor at baseline. After 1 year of NiOHT, all outcome measure scores improved by about 20% with respect to baseline data (P < 0.01 for all indices, except depressed mood). Finally, 33 patients performed the MMPI-2. High rates for hypochondriasis and depression were noted. Furthermore, most of the patients had high scores for anxiety, depression, and health concerns. This is the first study showing that NiOHT improves HRQoL of SNAS patients, which can be considered a "personalized medicine" approach.

authors

Rizzi A,Di Rienzo A,Buonomo A,Aruanno A,Carusi V,Ricci AG,Centrone M,Mezzacappa S,Romeo L,Schiavino D,Inchingolo R,Gasbarrini A,Nucera E

doi

10.1177/2058738420934629

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

2058738420934629

eissn

0394-6320

issn

2058-7384

journal_volume

34

pub_type

杂志文章
  • Sudden progression from impaired glucose tolerance to type 2 diabetes after discontinuation of administration of anti-tumor necrosis factor-alpha antibody infliximab.

    abstract::We present the case of a 45-year-old man with psoriasis and psoriatic arthritis and concomitant impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). In this patient, refractory to DMARD's, infliximab was started to control the arthritis. After achieving clinical remission of the disease, infliximab was...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201002300334

    authors: Ursini F,Succurro E,Grembiale A,Rudi S,Grembiale RD,Arturi F

    更新日期:2010-07-01 00:00:00

  • Plant-derived recombinant F1, V, and F1-V fusion antigens of Yersinia pestis activate human cells of the innate and adaptive immune system.

    abstract::Plague is still endemic in different regions of the world. Current vaccines raise concern for their side effects and limited protection, highlighting the need for an efficacious and rapidly producible vaccine. F1 and V antigens of Yersinia pestis, and F1-V fusion protein produced in Nicotiana benthamiana administered ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200902200115

    authors: Del Prete G,Santi L,Andrianaivoarimanana V,Amedei A,Domarle O,D' Elios MM,Arntzen CJ,Rahalison L,Mason HS

    更新日期:2009-01-01 00:00:00

  • Ultradian variation of nerve growth factor plasma levels in healthy and schizophrenic subjects.

    abstract::Some studies in animal models showed that several neurotrophins may be implicated in the regulation of light-dependent suprachiasmatic pacemaker and in other functions implicated in long-term memory acquisition during sleep. However, no data are known about the role played by NGF in ultradian regulation in humans. The...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 临床试验,杂志文章

    doi:10.1177/039463200401700316

    authors: Bersani G,Iannitelli A,Massoni E,Garavini A,Grilli A,Di Giannantonio M,Conti CM,Pancheri P

    更新日期:2004-09-01 00:00:00

  • Berberine reduces neuroglia activation and inflammation in streptozotocin-induced diabetic mice.

    abstract::We aimed to analyze the action of berberine on the neuropathic pain and neuroglia activation in experimental diabetes mellitus (DM) model. Diabetes in mice was induced by intraperitoneal injection of streptozotocin (STZ) followed by the administration of berberine. Mechanical allodynia and thermal hyperalgesia and act...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738419866379

    authors: Liu M,Gao L,Zhang N

    更新日期:2019-01-01 00:00:00

  • Acute impact of volcanic ash on asthma symptoms and treatment.

    abstract::Information about the impacts of disasters on health is useful for establishing hazard prediction maps and action plans of disaster management. This study aims at learning effective asthma management from the volcano disaster of Mount Asama eruption in Japan on September 1, 2004. We conducted a cross-sectional study t...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/03946320070200S203

    authors: Shimizu Y,Dobashi K,Hisada T,Ono A,Todokoro M,Iijima H,Utsugi M,Kakegawa S,Iizuka K,Ishizuka T,Morikawa A,Mori M

    更新日期:2007-04-01 00:00:00

  • Reduced sebum production in Turner syndrome: a study of twenty-two patients.

    abstract::Turner's syndrome (TS) is a genetic disorder caused by numeric and/or structural abnormalities of the X chromosome. In a previous study it was observed that acne is less frequent in TS than in the general population. Since the onset of acne in pre-pubertal or pubertal age is related to sebum production, this study eva...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201102400325

    authors: Brazzelli V,Calcaterra V,Muzio F,Klersy C,Larizza D,Borroni G

    更新日期:2011-07-01 00:00:00

  • Surgical debridement plus topical cyclosporine A in the treatment of vernal shield ulcers.

    abstract::Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of puncta...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201202500326

    authors: Caputo R,Pucci N,Mori F,De Libero C,Di Grande L,Bacci GM

    更新日期:2012-07-01 00:00:00

  • Evaluation of risk and benefit of oral immunomodulation using heat-killed enterococcus faecalis FK-23 preparation in healthy dogs.

    abstract::The risk and benefit of oral immunomodulation using heat-killed Enterococcus faecalis FK-23 preparation (FK-23) were evaluated in healthy dogs. Dogs were administered perorally 100 mg/kg of FK23 daily for 3 months. FK-23 did not affect the findings of complete blood count, leukocyte differential count, blood chemistry...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Hasegawa T,Shimazu N,Inomata T,Yamamoto T,Abe S,Yamaguchi H

    更新日期:1999-05-01 00:00:00

  • Electrochemical behaviour of titanium in ammine and stannous fluoride and chlorhexidine 0.2 percent mouthwashes.

    abstract::Titanium (Ti) is widely used in dentistry. Fluorides at acid pH could destabilize Ti oxide and make it susceptible to corrosion. The behaviour of IV grade machined Ti disks in 5 electrolytic solutions: Fusayama artificial saliva (Fas), ammine fluoride-stannous fluoride (Am-SnF2), 0.2 percent Chlorexidine (CHX) 0.20 pe...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201002300132

    authors: Quaranta A,Ronconi LF,Di Carlo F,Vozza I,Quaranta M

    更新日期:2010-01-01 00:00:00

  • Allergic and non-allergic drug hypersensitivity reactions in children.

    abstract::Adverse drug reactions (ADR) are an important medical problem. The aim of this study is to investigate the clinical characteristics of children with ADR and to assess the tolerability of alternative drugs in children (under 16 yrs of age) with a history of ADR. We studied 278 children (132 males and 146 females). Pati...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201002300324

    authors: Buonomo A,Altomonte G,De Pasquale T,Lombardo C,Pecora V,Sabato V,Colagiovanni A,Rizzi A,Aruanno A,Pascolini L,Patriarca G,Nucera E,Schiavino D

    更新日期:2010-07-01 00:00:00

  • Curcumin ameliorates insulin signalling pathway in brain of Alzheimer's disease transgenic mice.

    abstract::Deficits in glucose, impaired insulin signalling and brain insulin resistance are common in the pathogenesis of Alzheimer's disease (AD); therefore, some scholars even called AD type 3 diabetes mellitus. Curcumin can reduce the amyloid pathology in AD. Moreover, it is a well-known fact that curcumin has anti-oxidant a...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632016659494

    authors: Feng HL,Dang HZ,Fan H,Chen XP,Rao YX,Ren Y,Yang JD,Shi J,Wang PW,Tian JZ

    更新日期:2016-12-01 00:00:00

  • Role of nasal cytology.

    abstract::Nasal cytology represents a valid method in the differential diagnosis of allergic and non-allergic nasal diseases, as it is simple, safe, non-invasive, cost-effective, and easy to perform both in the medical and paediatric office. In particular, through cytological investigation it is possible to diagnose a group of ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:

    authors: Gelardi M,Fiorella ML,Russo C,Fiorella R,Ciprandi G

    更新日期:2010-01-01 00:00:00

  • Inhibitory effect of retinoic acid on proliferation, maturation and tryptase level in human leukemic mast cells (HMC-1).

    abstract::Mast cells play important role in allergic inflammation by releasing histamine, tryptase and several inflammatory cytokines. Human leukemic mast cells (HMC-1) have been used to study mast cell mediator and their role in inflammatory mechanisms. HMC-1 contain and release several inflammatory mediators, of which the pro...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200301600106

    authors: Alexandrakis MG,Kyriakou DS,Seretakis D,Boucher W,Letourneau R,Kempuraj D,Theoharides TC

    更新日期:2003-01-01 00:00:00

  • Bone microstructure evaluation near unloaded dental implants combining confocal scanning laser microscopy, circularly polarized light microscopy, and SEM backscattered electrons imaging.

    abstract::The aim of this report is to present a new investigative approach to implant dentistry based on the correlation of qualitative and quantitative data reported on the same figure by overlapping different images collected on the specimen with different investigative systems. Six unloaded titanium dental implants retrieve...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200702001s09

    authors: Traini T,Degidi M,Murmura G,Piattelli A,Caputi S

    更新日期:2007-01-01 00:00:00

  • Interleukin-2 enhances susceptibility of colon cancer cells to FasR mediated apoptosis by up-regulating Fas receptor level and down-regulating FAP-1 expression.

    abstract::Colon cancer cells are resistant to FasR-mediated apoptosis, which contributes to their evasion from immune attack by CTLs and NK cells. FasR refractoriness of the malignancies was reported to result from loss of Fas receptors and overepression of Fas-associated phosphatase-1 (FAP-1). Therefore, we investigated the ef...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Song E,Chen J,Antus B,Wang M,Xie Y,Yao H,Exton MS

    更新日期:2000-09-01 00:00:00

  • Corrigendum.

    abstract::Acosta YY, Montes-Casado M, Aragoneses L et al. (2014) Suppression of CD4(+) T lymphocyte activation "in vitro" and experimental encephalomyelitis "in vivo" by the phosphatidyl inositol 3-kinase inhibitor PIK-75. International Journal of Immunopathology and Pharmacology 27(1): 53-67. In the Acknowledgements section of...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,已发布勘误

    doi:10.1177/0394632015572738

    authors:

    更新日期:2015-03-01 00:00:00

  • Human lymphocytic B-leukemia cell line treatment with the bacterial toxin listeriolysin O and rituximab (anti-CD20 antibody): Effects of similar localization of their receptors.

    abstract::Small B-cell lymphocytic lymphoma/chronic lymphocytic leukemia, which typically affects elderly people, is a group of conditions that are not clinically uniform. It has been suggested that using the combined activity of the monoclonal antibody anti-CD20 (rituximab) and Listeria monocytogenes toxin listeriolysin O (LLO...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/0394632015595778

    authors: Gryzik M,Grzywocz Z,Wasilewska D,Kawiak J,Stachowiak R,Bielecki J,Hoser G

    更新日期:2015-09-01 00:00:00

  • Paraneoplastic sensitive neuropathy associated with anti-hu antibodies in a neuroendocrine tumor of duodenum: a case report.

    abstract::Paraneoplastic sensitive neuropathy is one of the most common presentations among a group of cancer-related disorders known as Paraneoplastic Neurological Syndromes (PNS). PNS likely have an autoimmune etiology since they have been associated with the presence of antibodies against neuronal antigens expressed by tumor...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201002300435

    authors: Nappi L,Formisano L,Damiano V,Matano E,Bianco R,Tortora G

    更新日期:2010-10-01 00:00:00

  • Genotype and phenotype relationship in MLSb resistance in Streptococcus pyogenes and Streptococcus agalactiae isolated in central Italy.

    abstract::The aim of this work is to study a correlation between phenotype and genotype in clinical isolates of erythromycin-resistant Streptococcus spp. Among the 25 erythromycin-resistant S. pyogenes, we detected six strains with iMLSB, nine with cMLSB and two with M phenotypes. Among 14 erythromycin-resistant S. agalactiae, ...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200601900418

    authors: Santino I,Scazzocchio F,Berlutti F,Cipriani P,Oliva B,Paola F,Del Piano M

    更新日期:2006-10-01 00:00:00

  • Sick building syndrome in like symptoms in emergency prefabricated accommodation.

    abstract::The present study investigated the sources of discomfort and the symptoms reported by earthquake victims residing in temporary emergency prefabricated accommodation (prefab). The investigation was carried out by means of a questionnaire. 203 prefab occupants and 13 inhabitants of houses, who were chosen as reference p...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/03946320040170S217

    authors: Muzi G,Accattoli MP,dell'Omo M,Frillici C,Sapia IE,Abbritti G

    更新日期:2004-05-01 00:00:00

  • alpha-Defensin levels in whole saliva of totally edentulous subjects.

    abstract::Salivary levels of alpha-defensins 1-4 and histatins 1, 3 and 5 were determined in 11 totally edentulous patients, 11 younger healthy adults with normal gingival mucosa (Control group I) and 8 subjects, age-matched with edentulous patients, having a minimum of 25 teeth (Control group II). Whole saliva was treated with...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200802100409

    authors: Fanali C,Inzitari R,Cabras T,Pisano E,Castagnola M,Celletti R,Manni A,Messana I

    更新日期:2008-10-01 00:00:00

  • Phloretin alleviates dinitrochlorobenzene-induced dermatitis in BALB/c mice.

    abstract::Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/2058738420929442

    authors: Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

    更新日期:2020-01-01 00:00:00

  • Progesterone inhibits mast cell secretion.

    abstract::Mast cells are involved in allergic reactions, where they secrete numerous vasoactive, inflammatory and nociceptive mediators in response to immunoglobulin E (IgE) and antigen. However, they have also been implicated in inflammatory conditions, such as painful bladder syndrome/interstitial cystitis (PBS/IC), irritable...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200601900408

    authors: Vasiadi M,Kempuraj D,Boucher W,Kalogeromitros D,Theoharides TC

    更新日期:2006-10-01 00:00:00

  • Cobalt nano-particles modulate cytokine in vitro release by human mononuclear cells mimicking autoimmune disease.

    abstract::The use of particles from micro to nanoscale provides benefits to diverse scientific fields, but because a large percentage of their atoms lie on the surface, nanomaterials could be highly reactive and pose potential risks to humans. Due to their wide range of application, Cobalt nano-particles are of great interest b...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Petrarca C,Perrone A,Verna N,Verginelli F,Ponti J,Sabbioni E,Di Giampaolo L,Dadorante V,Schiavone C,Boscolo P,Mariani Costantini R,Di Gioacchino M

    更新日期:2006-10-01 00:00:00

  • Protein kinase C zeta regulation of hypertrophic and apoptotic events occurring during rat neonatal heart development and growth.

    abstract::The development and growth of the rat heart implies hyperplasia, which stops at birth, and hypertrophy, allowing cardiac mass to grow in response to programmed genetic events along with to haemodynamic overload. Moreover, hypertrophy is accomplished to apoptosis which controls the final number of myocardial cells, del...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463200501800106

    authors: Centurione L,Di Giulio C,Santavenere E,Cacchio M,Sabatini N,Rapino C,Bianchi G,Rapino M,Bosco D,Antonucci A,Cataldi A

    更新日期:2005-01-01 00:00:00

  • Aurora B expression as a prognostic indicator and possible therapeutic target in oral squamous cell carcinoma.

    abstract::The aim of this study is to investigate the expression of the chromosomal passenger protein Aurora B and its activated (phosphorylated) form in a large series of human oral squamous cell cancers (OSCC) and to evaluate its clinical and prognostic significance. Western blotting analysis revealed overexpression of both A...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201102400110

    authors: Pannone G,Hindi SA,Santoro A,Sanguedolce F,Rubini C,Cincione RI,De Maria S,Tortorella S,Rocchetti R,Cagiano S,Pedicillo C,Serpico R,Lo Muzio L,Bufo P

    更新日期:2011-01-01 00:00:00

  • Subglotic malt-lymphoma of the larynx: an unusual presentation of chronic cough.

    abstract::Extranodal non-Hodgkin lymphomas limited to the larynx are rare, accounting for less than 1% of all laryngeal neoplasms. The most common site of development of primary laryngeal lymphomas is the supraglottic region. In most cases, the presenting symptoms are hoarseness, dysphagia, dyspnea, and cervical lymphadenopathy...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 信件

    doi:10.1177/039463201402700319

    authors: Zapparoli M,Trolese AR,Remo A,Sina S,Bonetti A,Micheletto C

    更新日期:2014-07-01 00:00:00

  • Heparin protects BALB/c mice from mite-induced airway allergic inflammation.

    abstract::More and more studies have demonstrated the anti-inflammatory effects of heparin. However, in the aspect of allergic airway inflammation, data about its daily use in animal model is scarce. To evaluate the efficacy of 22-day intranasal heparin administration in mite-induced airway allergic inflammation in BALB/c mice,...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:10.1177/039463201302600208

    authors: Fu LS,Tsai JJ,Chen YJ,Lin HK,Tsai MC,Chang MD

    更新日期:2013-04-01 00:00:00

  • Specific immunotherapy in children: the evidence.

    abstract::Specific immunotherapy (SIT) is the only treatment able to not only act on the symptoms of allergy but also act on the causes. At present, SIT may be administered in two forms: subcutaneous (SCIT) and sublingual immunotherapy (SLIT). SCIT represents the standard modality of treatment while SLIT has recently been intro...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章,评审

    doi:10.1177/03946320110240S413

    authors: La Rosa M,Lionetti E,Leonardi S,Salpietro A,Bianchi L,Salpietro C,Miraglia Del Giudice M,Ciprandi G,Marseglia GL

    更新日期:2011-10-01 00:00:00

  • Detection of hepatitis C virus-RNA in saliva from chronically HCV-infected patients.

    abstract::The possibility of the non-parenteral Hepatitis C Virus (HCV) transmission is supported by the demonstration that the actual virus is present in several body fluids, including saliva. From a review of the literature many investigators have found the presence of HCV-RNA in saliva, however, widely contrasting results em...

    journal_title:International journal of immunopathology and pharmacology

    pub_type: 杂志文章

    doi:

    authors: Pastore L,Fiore JR,Tateo M,De Benedittis M,Petruzzi M,Casalino C,Genchi C,Lo Muzio L,Angarano G,Serpico R

    更新日期:2006-01-01 00:00:00