miR-199a-5p inhibits proliferation and induces apoptosis in hemangioma cells through targeting HIF1A.

abstract：:Blockade of the interactions between CD28/CTLA-4 and their ligands, CD80 (B7, B7.1)/CD86 (B70, B7.2), is an attractive means to induce antigen-specific peripheral tolerance in autoimmune disease and organ transplantation. In this study, we generated and characterized a monoclonal antibody (Clone 4E5) against human CD8...

journal_title：International journal of immunopathology and pharmacology

authors： Shi Q,Gao ZY,Xie F,Wang LF,Gu YP,Yang TJ,Huang L,Qian QH,Qiu YH

更新日期：2011-07-01 00:00:00

abstract：:After birth various bacterial species, mainly streptococci, colonize the oral cavity and are frequently isolated from carious lesions in children. Previous studies suggest that an earlier colonization of a child's mouth by cariogenic organisms might be related to a higher risk of caries. The aim of this study is to as...

journal_title：International journal of immunopathology and pharmacology

authors： Duse M,Zicari AM,Berlutti F,Ernesti I,Occasi F,Leonardi L,Polimeni A

更新日期：2014-01-01 00:00:00

abstract：:Pseudoxanthoma Elasticum-like Papillary Dermal Elastolysis (PXE-PDE) is a peculiar idiopathic elastolytic disorder that clinically resembles Psudoxanthoma elasticum(PXE). It is histologically characterized by a total or partial loss of elastic fibers in the papillary dermis. It more often affects elderly women and is ...

journal_title：International journal of immunopathology and pharmacology

authors： Pranteda G,Muscianese M,Marmo G,Fidanza L,Pranteda G,Tamburi F,Bottoni U,Nisticò S

更新日期：2013-10-01 00:00:00

abstract：:We studied the significance of age as a factor affecting prognosis and anti-AChR antibody levels in myasthenia gravis, comparing patients with symptom onset before 50 (37 patients) and at or after 50 (33 patients). More of the older patients, compared to younger ones (69.9% versus 32.4%,p<0. 05) progress...

journal_title：International journal of immunopathology and pharmacology

authors： Kapinas K,Kimiskidis VK,Kazis AD,Kokkas B,Tsolaki M,Georgiadis G

更新日期：1999-09-01 00:00:00

abstract：:In an effort to define the antigenic mechanism that contributes to beneficial therapeutic outcome in patients with polycythemia vera (PV), we screened a human testis cDNA library with serological cloning derived from sera of three PV patients who had undergone therapeutic-induced remission. As a result, we identified ...

journal_title：International journal of immunopathology and pharmacology

authors： Xiong Z,Liu E,Yan Y,Silver RT,Yang F,Chen IH,Hodge I,Verstovsek S,Segura FJ,Wang H,Prchal J,Yang XF

更新日期：2007-04-01 00:00:00

abstract：:Serum samples from Bulgarian patients with physician-diagnosed erythema migrans (EM) (n=105) were examined using Borrelia burgdorferi ELISA (Boehring, Germany) after previous absorption with Treponema phagedenis. For IgM antibody detection sera were additionally pretreated with anti-IgG serum (RF absorbent). Serum sam...

journal_title：International journal of immunopathology and pharmacology

authors： Christova I

更新日期：2003-09-01 00:00:00

abstract：:We wanted to determine whether a paradigm switch in Th1/Th2 phenotypes in splenic lymphocytes could be induced in BALB/c mice after ultraviolet-B (UVB) irradiation and exposure to pollen. Results showed that UVB irradiation increased IL-1 but decreased IL-12 in vivo, and caused significant cell destruction of macropha...

journal_title：International journal of immunopathology and pharmacology

authors： Kasahara S,Fugo H,Cooper EL,Wago H

更新日期：2001-05-01 00:00:00

abstract：:In order to understand the immunogenicity of a tumor-associated antigen (TAA), Ras family small GTP binding protein (Ra1A) in hepatocellular carcinoma (HCC), autoantibody responses to RalA were evaluated by enzyme-linked immunosorbent assay (ELISA), Western blotting and indirect immunofluorescence assay in sera from p...

journal_title：International journal of immunopathology and pharmacology

authors： Wang K,Chen Y,Liu S,Qiu S,Gao S,Huang X,Zhang J,Peng X,Qiani W,Zhang JY

更新日期：2009-07-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:An association between human immunodeficiency virus type I (HIV-1) protease inhibitors (PIs) and galactorrhoea/hyperprolactinemia adverse effect has recently been reported in four HIV-1-infected women treated with PIs (indinavir, nelfinavir, ritonavir or saquinavir). This could be explained by a direct effect of riton...

journal_title：International journal of immunopathology and pharmacology

authors： Orlando G,Brunetti L,Vacca M

更新日期：2002-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of the Heat Shock Proteins GroES, GroEL and DnaK on the expression of the costimulatory molecules CD80/CD86 in B cells and macrophages. The interactions among these molecules are able to highly influence the immune response through the regulation of cytokine liberation ...

journal_title：International journal of immunopathology and pharmacology

authors： Galdiero M,Pisciotta MG,Gorga F,Petrillo G,Marinelli A,Galdiero E

更新日期：2005-10-01 00:00:00

abstract：:Progressive ageing is associated with an increment of biomolecules modified through oxidation as a result of the action of free radicals deriving from reactive oxygen species that attack biomolecules. During ageing many alterations of renal functions have been reported. Renal ageing is associated with a progressive de...

journal_title：International journal of immunopathology and pharmacology

authors： De Lutiis MA,Felaco M,Gizzi F,Patruno A,Speranza L,Di Giulio C,Conti P,Castellani ML,Petrarca C,Grilli A

更新日期：2004-09-01 00:00:00

abstract：:Colon cancer cells are resistant to FasR-mediated apoptosis, which contributes to their evasion from immune attack by CTLs and NK cells. FasR refractoriness of the malignancies was reported to result from loss of Fas receptors and overepression of Fas-associated phosphatase-1 (FAP-1). Therefore, we investigated the ef...

journal_title：International journal of immunopathology and pharmacology

authors： Song E,Chen J,Antus B,Wang M,Xie Y,Yao H,Exton MS

更新日期：2000-09-01 00:00:00

abstract：:More and more studies have demonstrated the anti-inflammatory effects of heparin. However, in the aspect of allergic airway inflammation, data about its daily use in animal model is scarce. To evaluate the efficacy of 22-day intranasal heparin administration in mite-induced airway allergic inflammation in BALB/c mice,...

journal_title：International journal of immunopathology and pharmacology

authors： Fu LS,Tsai JJ,Chen YJ,Lin HK,Tsai MC,Chang MD

更新日期：2013-04-01 00:00:00

abstract：:Nickel ingested with food can elicit either systemic cutaneous or gastrointestinal symptoms causing a systemic nickel allergy syndrome (SNAS) that can be treated with tolerance by oral ingestion of the metal. It has been suggested that interleukins 2 (IL-2) and 10 (IL-10) are involved in the mechanisms underlying oral...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardi L,Carni A,Loschiavo G,Gangemi S,Tigano V,Arena E,Mannucci C,Calapai G

更新日期：2013-01-01 00:00:00

abstract：:Hematide is a synthetic PEGylated peptidic erythropoiesis stimulating agent (ESA) that is presently being developed for the correction of anemia in patients with chronic renal failure. Unlike currently marketed ESAs, Hematide does not possess any sequence homology to erythropoietin (EPO) and has not elicited moribund ...

journal_title：International journal of immunopathology and pharmacology

authors： Woodburn KW,Schatz PJ,Fong KL,Beaumier P

更新日期：2010-01-01 00:00:00

abstract：:The autoptical observations commonly ascribed to sepsis deal with unspecific general and local signs of inflammation or ischemia, such as myocardial inflammation, pulmonary edema and infiltration, cerebral swallowing, and tubular necrosis in the kidney. In the two last decades, some studies have been carried out to im...

journal_title：International journal of immunopathology and pharmacology

authors： La Russa R,Maiese A,Viola RV,De Matteis A,Pinchi E,Frati P,Fineschi V

更新日期：2019-01-01 00:00:00

abstract：:Occupational exposure to chromium may cause airway inflammation and bronchial asthma. In this study we investigated the effect of chromium on the respiratory tract of exposed and non-exposed electroplating workers using spirometry and analysis of induced sputum (IS), exhaled breath condensate (EBC) and nasal lavage fl...

journal_title：International journal of immunopathology and pharmacology

authors： Murgia N,Muzi G,Dell' Omo M,Montuschi P,Melchiorri D,Ciabattoni G,Abbritti EP,Orazi N,Sapia IE,Abbritti G

更新日期：2006-10-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Specific immunotherapy (SIT) is the only treatment able to not only act on the symptoms of allergy but also act on the causes. At present, SIT may be administered in two forms: subcutaneous (SCIT) and sublingual immunotherapy (SLIT). SCIT represents the standard modality of treatment while SLIT has recently been intro...

journal_title：International journal of immunopathology and pharmacology

authors： La Rosa M,Lionetti E,Leonardi S,Salpietro A,Bianchi L,Salpietro C,Miraglia Del Giudice M,Ciprandi G,Marseglia GL

更新日期：2011-10-01 00:00:00

abstract：:Since the beginning of the 21st century, carbon-based nanomaterials (CNTs) have been introduced in pharmacy and medicine for drug delivery system in therapeutics. CNTs have proved able to transport a wide range of molecules across membranes and into living cells; therefore, they have attracted great interest in biomed...

journal_title：International journal of immunopathology and pharmacology

authors： Lamberti M,Pedata P,Sannolo N,Porto S,De Rosa A,Caraglia M

更新日期：2015-03-01 00:00:00

abstract：:Mast cells are involved in allergic reactions, where they secrete numerous vasoactive, inflammatory and nociceptive mediators in response to immunoglobulin E (IgE) and antigen. However, they have also been implicated in inflammatory conditions, such as painful bladder syndrome/interstitial cystitis (PBS/IC), irritable...

journal_title：International journal of immunopathology and pharmacology

authors： Vasiadi M,Kempuraj D,Boucher W,Kalogeromitros D,Theoharides TC

更新日期：2006-10-01 00:00:00

abstract：:Ink spot lentigo, also known as reticulated black solar lentigo, is a melanotic macula commonly described in fair-skinned individuals on sun-exposed areas of the body. Clinically it is a darkly pigmented type of solar lentigo; herein the term ink spot lentigo. In contrast to common solar lentigines, ink spot lentigo i...

journal_title：International journal of immunopathology and pharmacology

authors： Bottoni U,Nisticò S,Amoruso GF,Schipani G,Arcidiacono V,Scali E,Tassone P,Greco M,Amorosi A

更新日期：2013-10-01 00:00:00

abstract：:This study aimed to investigate the clinical significance of serum microRNA-219-5p (miR-219-5p) in patients with multiple organ dysfunction syndrome (MODS) caused by acute paraquat (PQ) poisoning, and its correlation with Toll-like Receptor 4 (TLR4). Luciferase reporter assay was used to investigate in vitro the corre...

journal_title：International journal of immunopathology and pharmacology

authors： Dai Y,Liu X,Gao Y

更新日期：2020-01-01 00:00:00

abstract：:Although dental implants have undergone impressive evolution in recent years, periimplantitis still remains a relevant problem and information on the susceptibility of commercial implants to bacterial colonization is insufficient. This work evaluated the susceptibility of different commercial implants to bacterial col...

journal_title：International journal of immunopathology and pharmacology

authors： Passariello C,Pera F,Gigola P

更新日期：2013-04-01 00:00:00

abstract：:The role of inhaled corticosteroids in asthma exacerbation is debated. We compared high doses of nebulized budesonide versus high doses of nebulized flunisolide, in association with a short-acting beta-2-agonist, in the treatment of moderate asthma exacerbation in preschool children. In this randomized, parallel group...

journal_title：International journal of immunopathology and pharmacology

authors： Decimo F,Maiello N,Miraglia Del Giudice M,Amelio R,Capristo C,Capristo AF

更新日期：2009-04-01 00:00:00

abstract：:The aim of this study was to investigate the possible protective effects of diallyl trisulfide (DATS) against naphthalene-induced oxidative and inflammatory damage in the livers and lungs of mice. Elevated serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels showed significant hepatic damag...

journal_title：International journal of immunopathology and pharmacology

authors： Zhang F,Zhang Y,Wang K,Liu G,Yang M,Zhao Z,Li S,Cai J,Cao J

更新日期：2016-06-01 00:00:00

abstract：:Icatibant, an antagonist of the bradykinin B2 receptor, was approved for the treatment of acute attacks of hereditary angioedema in the EU in 2008. This paper presents the case of a 65-year-old woman affected by frequent acute attacks of hereditary angioedema who benefitted from a change of therapy to icatibant, follo...

journal_title：International journal of immunopathology and pharmacology

authors： Firinu D,Barca MP,Serusi L,Lorrai MM,Peralta MM,Manconi PE,Del Giacco SR

更新日期：2012-01-01 00:00:00

abstract：:In a preliminary study a reduction in natural killer (NK) cell activity in peripheral blood lymphocytes (PBL) was observed in a group of workers exposed to levels of extremely low frequency-magnetic fields (ELF-MF) exceeding 1 microT. This study was performed to confirm the results. In 121 workers engaged in various o...

journal_title：International journal of immunopathology and pharmacology

authors： Gobba F,Bargellini A,Bravo G,Scaringi M,Cauteruccio L,Borella P

更新日期：2009-10-01 00:00:00

abstract：:The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered. To address this issue, we first identified an HLA-A2.1-restricted T cell antigen epitope of SEREX-identified tumor antigen CML66L, 66Pa....

journal_title：International journal of immunopathology and pharmacology

authors： Yan Y,Chen Y,Yang F,Chen IH,Xiong Z,Wang J,Lachman LB,Wang H,Yang XF

更新日期：2007-01-01 00:00:00