Human lymphocytic B-leukemia cell line treatment with the bacterial toxin listeriolysin O and rituximab (anti-CD20 antibody): Effects of similar localization of their receptors.

abstract：:Colon cancer cells are resistant to FasR-mediated apoptosis, which contributes to their evasion from immune attack by CTLs and NK cells. FasR refractoriness of the malignancies was reported to result from loss of Fas receptors and overepression of Fas-associated phosphatase-1 (FAP-1). Therefore, we investigated the ef...

journal_title：International journal of immunopathology and pharmacology

authors： Song E,Chen J,Antus B,Wang M,Xie Y,Yao H,Exton MS

更新日期：2000-09-01 00:00:00

abstract：:Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development o...

journal_title：International journal of immunopathology and pharmacology

authors： Mastrangelo F,Piccirilli M,Dolci M,Teté S,Speranza L,Patruno A,Gizzi F,Felaco M,Artese L,De Lutiis MA

更新日期：2005-07-01 00:00:00

abstract：:Surgical stress induces complex modifications in the hemodynamic, metabolic, neuro-hormonal and immune response of the individual. The magnitude of these alterations depends on preoperative events leading to surgery, the severity of surgical trauma, and also on post-operative/post-traumatic complications (multiple hit...

journal_title：International journal of immunopathology and pharmacology

authors： Cardinale F,Chinellato I,Caimmi S,Peroni DG,Franceschini F,Miraglia Del Giudice M,Bernardini R

更新日期：2011-07-01 00:00:00

abstract：:The question of whether T cell responses to SEREX-defined tumor antigens are under regulation of naturally occurring CD4+CD25+ regulatory T cells (nTreg cells) has not been answered. To address this issue, we first identified an HLA-A2.1-restricted T cell antigen epitope of SEREX-identified tumor antigen CML66L, 66Pa....

journal_title：International journal of immunopathology and pharmacology

authors： Yan Y,Chen Y,Yang F,Chen IH,Xiong Z,Wang J,Lachman LB,Wang H,Yang XF

更新日期：2007-01-01 00:00:00

abstract：:This study aimed to investigate the effects of a novel patented Mg-3Nd-0.2Zn-0.4Zr (weight %, JDBM) alloy on osteoblastic cell function, as these cells play an important role in bone repair and remodeling. The associated effects of the JDBM alloy on osteoblastic cell function involving cell adhesion, cell proliferatio...

journal_title：International journal of immunopathology and pharmacology

authors： Wang Y,Ouyang Y,Pang X,Mao L,Yuan G,Jiang Y,He Y

更新日期：2012-07-01 00:00:00

abstract：:This update on treatment of asthma exacerbations in children is the result of an Italian Pediatric Society Task-force, made up of a panel of experts working in 2007-2008. The aim is to give clear indications on the use of the drugs most employed in children, grading the quality of evidence and the strength of recommen...

journal_title：International journal of immunopathology and pharmacology

authors： Indinnimeo L,Bertuola F,Cutrera R,De Benedictis FM,Di Pietro P,Duse M,Gianiorio P,Indirli G,La Grutta S,La Rosa M,Longhi R,Miceli Sopo S,Miglioranzi P,Miraglia Del Giudice M,Monaco F,Radzik D,Renna S,Snijders D,Zampog

更新日期：2009-10-01 00:00:00

abstract：:Hypertension has been suggested to exert pro-inflammatory actions through increased expression of several mediators, including chemokines. Chemokines are involved in inflammatory and autoimmune disorders, and in the formation of atherosclerotic lesions through promotion of inflammatory cell migration. The aim of this ...

journal_title：International journal of immunopathology and pharmacology

authors： Antonelli A,Fallahi P,Ferrari SM,Ghiadoni L,Virdis A,Mancusi C,Centanni M,Taddei S,Ferrannini E

更新日期：2012-04-01 00:00:00

abstract：:Information about the impacts of disasters on health is useful for establishing hazard prediction maps and action plans of disaster management. This study aims at learning effective asthma management from the volcano disaster of Mount Asama eruption in Japan on September 1, 2004. We conducted a cross-sectional study t...

journal_title：International journal of immunopathology and pharmacology

authors： Shimizu Y,Dobashi K,Hisada T,Ono A,Todokoro M,Iijima H,Utsugi M,Kakegawa S,Iizuka K,Ishizuka T,Morikawa A,Mori M

更新日期：2007-04-01 00:00:00

abstract：:Cryopyrin-associated periodic syndromes are categorized as a spectrum of three autoinflammatory diseases, namely familial cold auto-inflammatory syndrome, Muckle-Wells syndrome and chronic infantile neurological cutaneous articular syndrome. All are caused by mutations in the NLRP3 gene coding for cryopyrin and result...

journal_title：International journal of immunopathology and pharmacology

authors： Cantarini L,Lucherini OM,Frediani B,Brizi MG,Bartolomei B,Cimaz R,Galeazzi M,Rigante D

更新日期：2011-10-01 00:00:00

abstract：:We aimed to analyze the action of berberine on the neuropathic pain and neuroglia activation in experimental diabetes mellitus (DM) model. Diabetes in mice was induced by intraperitoneal injection of streptozotocin (STZ) followed by the administration of berberine. Mechanical allodynia and thermal hyperalgesia and act...

journal_title：International journal of immunopathology and pharmacology

authors： Liu M,Gao L,Zhang N

更新日期：2019-01-01 00:00:00

abstract：:Arabinoxylan rice bran (MGN-3/Biobran) is a potent biological response modifier (BRM) that activates natural killer (NK) cells, T cells and monocytes. Currently, little is known regarding the effects of MGN-3 on dendritic cells (DCs), the cell type that bridges innate and adaptive immunity. Therefore, we examined the ...

journal_title：International journal of immunopathology and pharmacology

authors： Ghoneum M,Agrawal S

更新日期：2011-10-01 00:00:00

abstract：:The role of profilin as an allergen has long been questioned. The capacity of profilin to induce respiratory symptoms has recently been demonstrated; moreover, over 50% of patients sensitized to profilin experienced symptoms after the ingestion of plant-derived foods, suggesting that profilin should be considered as a...

journal_title：International journal of immunopathology and pharmacology

authors： Nucera E,Aruanno A,Rizzi A,Pecora V,Patriarca G,Buonomo A,Mezzacappa S,Schiavino D

更新日期：2016-09-01 00:00:00

abstract：:Specific immunotherapy (SIT) is the only treatment able to not only act on the symptoms of allergy but also act on the causes. At present, SIT may be administered in two forms: subcutaneous (SCIT) and sublingual immunotherapy (SLIT). SCIT represents the standard modality of treatment while SLIT has recently been intro...

journal_title：International journal of immunopathology and pharmacology

authors： La Rosa M,Lionetti E,Leonardi S,Salpietro A,Bianchi L,Salpietro C,Miraglia Del Giudice M,Ciprandi G,Marseglia GL

更新日期：2011-10-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic inflammatory disease of the skin that substantially affects a patient's quality of life. While steroids are the most common therapy used to temporally alleviate the symptoms of AD, effective and nontoxic alternatives are urgently needed. In this study, we utilized a natural, plant-d...

journal_title：International journal of immunopathology and pharmacology

authors： Wu CS,Lin SC,Li S,Chiang YC,Bracci N,Lehman CW,Tang KT,Lin CC

更新日期：2020-01-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

journal_title：International journal of immunopathology and pharmacology

authors： Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

更新日期：2012-04-01 00:00:00

abstract：:Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its s...

journal_title：International journal of immunopathology and pharmacology

authors： Castellani ML,Felaco P,Galzio RJ,Tripodi D,Toniato E,De Lutiis MA,Fulcheri M,Caraffa A,Antinolfi P,Tetè S,Felaco M,Conti F,Pandolfi F,Theoharides TC,Shaik-Dasthagirisaheb YB

更新日期：2010-07-01 00:00:00

abstract：:We examined the expression of human leukocyte antigen (HLA) and composition of differentiated T cells in the peripheral blood to understand the characteristics of the immune changes in patients with adult-onset Still's disease (AOSD). This study enrolled patients with AOSD (n = 14), patients with rheumatoid arthritis ...

journal_title：International journal of immunopathology and pharmacology

authors： Jung JY,Choi B,Sayeed HM,Suh CH,Kim YW,Kim HA,Sohn S

更新日期：2018-01-01 00:00:00

abstract：:Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid diseases. However, al...

journal_title：International journal of immunopathology and pharmacology

authors： Wang N,Liu R,Liu Y,Zhang R,He L

更新日期：2016-12-01 00:00:00

abstract：:Finding new strategies to counteract periprosthetic infection and implant failure is a main target in orthopedics. Staphylococcus aureus, the leading etiologic agent of orthopedic implant infections, is able to enter and kill osteoblasts, to stimulate pro-inflammatory chemokine secretion, to recruit osteoclasts, and t...

journal_title：International journal of immunopathology and pharmacology

authors： Selan L,Papa R,Ermocida A,Cellini A,Ettorre E,Vrenna G,Campoccia D,Montanaro L,Arciola CR,Artini M

更新日期：2017-12-01 00:00:00

abstract：:United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persis...

journal_title：International journal of immunopathology and pharmacology

authors： Profita M,Montuschi P,Bonanno A,Riccobono L,Montalbano AM,Ciabattoni G,Albano GD,Liotta G,Bousquet J,Gjomarkaj M,La Grutta S

更新日期：2010-10-01 00:00:00

abstract：:We studied the significance of age as a factor affecting prognosis and anti-AChR antibody levels in myasthenia gravis, comparing patients with symptom onset before 50 (37 patients) and at or after 50 (33 patients). More of the older patients, compared to younger ones (69.9% versus 32.4%,p<0. 05) progress...

journal_title：International journal of immunopathology and pharmacology

authors： Kapinas K,Kimiskidis VK,Kazis AD,Kokkas B,Tsolaki M,Georgiadis G

更新日期：1999-09-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Although Sho-seiryu-to (SST), used as a traditional herbal (Kampo) medicine mainly in China and Korea, is shown to have immunomodulating potential, such as an anti-allergic one, its underlying mechanism has not been completely clarified. To partially address the issue, we explored its effects on allergen-exposed monon...

journal_title：International journal of immunopathology and pharmacology

authors： Tanaka M,Inoue K,Kitamura Y,Shimada A,Takano H

更新日期：2014-10-01 00:00:00

abstract：:In recent decades, the role played by the immune response to bacteria in the pathogenesis of chronic periodontal disease (PD) has long been studied. Although from the clinical point of view, adequate oral hygiene is essential to ensure a satisfactory response of the host to infections, modulation of the reaction of im...

journal_title：International journal of immunopathology and pharmacology

authors： Luca S,Francesco C,Damiano M,Alessandro N,Silvia C,Diego R,Michele R,Marco S

更新日期：2019-01-01 00:00:00

abstract：:The aim of this study is to investigate the expression of the chromosomal passenger protein Aurora B and its activated (phosphorylated) form in a large series of human oral squamous cell cancers (OSCC) and to evaluate its clinical and prognostic significance. Western blotting analysis revealed overexpression of both A...

journal_title：International journal of immunopathology and pharmacology

authors： Pannone G,Hindi SA,Santoro A,Sanguedolce F,Rubini C,Cincione RI,De Maria S,Tortorella S,Rocchetti R,Cagiano S,Pedicillo C,Serpico R,Lo Muzio L,Bufo P

更新日期：2011-01-01 00:00:00

abstract：:Cellular immune response has been demonstrated to play a role in the control of human cytomegalovirus (HCMV) replication in organ transplant recipients. Herein, HCMV-specific T-cell response and association to the onset of organ infection/disease were prospectively evaluated by EliSPOT assay in a population of 46 lung...

journal_title：International journal of immunopathology and pharmacology

authors： Costa C,Saldan A,Sinesi F,Sidoti F,Balloco C,Simeone S,Piceghello A,Mantovani S,Di Nauta A,Solidoro P,Cavallo R

更新日期：2012-10-01 00:00:00

abstract：UNLABELLED:Insulin-like growth factor-1 (IGF-1) is involved in regulating the Th-1/Th-2 balance, favoring the development of the Th-2 compartment which enhances fibrosis, one of the main characteristics of Chronic Lung Disease (CLD) in premature newborns. Limited data is available concerning a possible association betw...

journal_title：International journal of immunopathology and pharmacology

authors： Capoluongo E,Vento G,Ameglio F,Lulli P,Matassa PG,Carrozza C,Santini SA,Antenucci M,Castagnola M,Giardina B,Romagnoli C,Zuppi C

更新日期：2006-01-01 00:00:00

abstract：:Immunosuppressive treatment has changed the prognosis of Lupus nephritis over time, but improvement in prognosis is difficult to analyze in different historical periods, and should be better demonstrated in comparison with life expectancy of sex-and age-matched people. Long-term patient and renal survival of 90 patien...

journal_title：International journal of immunopathology and pharmacology

authors： Stratta P,Mesiano P,Campo A,Grill A,Ferrero S,Santi S,Besso L,Mazzucco G,Rosso S,Spitale A,Fop F,Ciccone G

更新日期：2009-10-01 00:00:00

abstract：:Pseudoxanthoma Elasticum-like Papillary Dermal Elastolysis (PXE-PDE) is a peculiar idiopathic elastolytic disorder that clinically resembles Psudoxanthoma elasticum(PXE). It is histologically characterized by a total or partial loss of elastic fibers in the papillary dermis. It more often affects elderly women and is ...

journal_title：International journal of immunopathology and pharmacology

authors： Pranteda G,Muscianese M,Marmo G,Fidanza L,Pranteda G,Tamburi F,Bottoni U,Nisticò S

更新日期：2013-10-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00