Green tea polyphenols protect PC12 cells against H2O2-induced damages by upregulating lncRNA MALAT1.

abstract：INTRODUCTION:Indoleamine 2,3-dioxygenase (IDO) was a potential tumor immunotherapy target. IDO inhibitors showed inconsistent results in clinical trials, but no preclinical comparative study was reported. The purpose of this study was to evaluate the differences of representative IDO inhibitors (PCC0208009, INCB024360,...

journal_title：International journal of immunopathology and pharmacology

authors： Jiang X,Li X,Zheng S,Du G,Ma J,Zhang L,Wang H,Tian J

更新日期：2020-01-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of the Heat Shock Proteins GroES, GroEL and DnaK on the expression of the costimulatory molecules CD80/CD86 in B cells and macrophages. The interactions among these molecules are able to highly influence the immune response through the regulation of cytokine liberation ...

journal_title：International journal of immunopathology and pharmacology

authors： Galdiero M,Pisciotta MG,Gorga F,Petrillo G,Marinelli A,Galdiero E

更新日期：2005-10-01 00:00:00

abstract：:Bone resection is the choice treatment of malignant bone tumors. Tumor prosthesis is one of the most common solutions of reconstruction following resection of bone tumor located to the metaphysis of long bones. Periprosthetic infections are a frequent complication of limb-salvage surgery which is largely due to prolon...

journal_title：International journal of immunopathology and pharmacology

authors： Graci C,Maccauro G,Muratori F,Spinelli MS,Rosa MA,Fabbriciani C

更新日期：2010-10-01 00:00:00

abstract：:Serum samples from Bulgarian patients with physician-diagnosed erythema migrans (EM) (n=105) were examined using Borrelia burgdorferi ELISA (Boehring, Germany) after previous absorption with Treponema phagedenis. For IgM antibody detection sera were additionally pretreated with anti-IgG serum (RF absorbent). Serum sam...

journal_title：International journal of immunopathology and pharmacology

authors： Christova I

更新日期：2003-09-01 00:00:00

abstract：:Cytokines are immunal regulatory proteins, however they also play a relevant role in inflammatory diseases. IL-31 is a newly discovered cytokine expressed primarily in TH2 cells, introduced by activated CD4+ T cells. IL-31 is capable of inducing chemokines and other cytokines in several inflammatory diseases via its s...

journal_title：International journal of immunopathology and pharmacology

authors： Castellani ML,Felaco P,Galzio RJ,Tripodi D,Toniato E,De Lutiis MA,Fulcheri M,Caraffa A,Antinolfi P,Tetè S,Felaco M,Conti F,Pandolfi F,Theoharides TC,Shaik-Dasthagirisaheb YB

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Inflammation, which is a hallmark of asthma, is one of the main sources of oxidative stress in the human body. Thiols are powerful antioxidants that protect cells against the consequences of oxidative stress. We aimed to investigate whether asthma and montelukast monotherapy affect the total plasma thiol poo...

journal_title：International journal of immunopathology and pharmacology

authors： Dilek F,Ozkaya E,Kocyigit A,Yazici M,Guler EM,Dundaroz MR

更新日期：2016-03-01 00:00:00

abstract：:Many oncogenis and tumour suppressor genes found inside normal and pathological cells are fundamental for the processes of development, proliferation and tissue differentiation. The purpose of our study is to show the presence and a possible relationship of the VEGF protein during different phases of the development o...

journal_title：International journal of immunopathology and pharmacology

authors： Mastrangelo F,Piccirilli M,Dolci M,Teté S,Speranza L,Patruno A,Gizzi F,Felaco M,Artese L,De Lutiis MA

更新日期：2005-07-01 00:00:00

abstract：:Exhaled nitric oxide (FeNO) has been associated with bronchial eosinophilia and with airway hyperresponsiveness (AHR) in mild stable asthma. We previously demonstrated in a large project that allergen exposure is able to raise FeNO and to worsen AHR to bradykinin. We postulated that allergen-induced increase in FeN...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Di Stefano A,Silvestri M,Van Schadewijk AM,Malerba M,Hiemstra PS,Sterk PJ

更新日期：2012-01-01 00:00:00

abstract：:The narrow therapeutic index and large inter-individual variability in sirolimus pharmacokinetics (PK) make therapeutic drug monitoring (TDM) necessary. Factors responsible for PK variability are not well understood, and published PK studies do not include pediatric patients with immune cytopenia. The objective of thi...

journal_title：International journal of immunopathology and pharmacology

authors： Cheng X,Zhao Y,Gu H,Zhao L,Zang Y,Wang X,Wu R

更新日期：2020-01-01 00:00:00

abstract：:IgG4 have been hypothesized to act as blocking antibodies capable of preventing IgE-mediated effector cell triggering. This study aims to evaluate the changes in IgG4 in children during a period of natural antigen avoidance. Serum IgE and IgG4 were evaluated in a group of asthmatic children, aged between 7 and 17 year...

journal_title：International journal of immunopathology and pharmacology

authors： Piacentini GL,Guerresi S,Kantar A,Lubrano L,Olivieri F,Boner AL,Peroni DG

更新日期：2011-10-01 00:00:00

abstract：:Isoprostanes are prostaglandin isomers produced from the peroxidation of polyunsaturated fatty acids from the cellular membrane. They have been used as a specific index of cellular lipoperoxidation and as an indirect measure of oxidative stress. However, these molecules also present several biological activities. An o...

journal_title：International journal of immunopathology and pharmacology

authors： Belli R,Amerio P,Brunetti L,Orlando G,Toto P,Proietto G,Vacca M,Tulli A

更新日期：2005-07-01 00:00:00

abstract：:To prevent and control disease caused by exposure to various agents, it is necessary to determine the harmful level of intervention and to establish a method for measuring that level. In-air microparticle-induced X-ray emission (in-air micro-PIXE) analysis is based on irradiation of specimens with a proton ion microbe...

journal_title：International journal of immunopathology and pharmacology

authors： Matsuzaki S,Shimizu Y,Dobashi K,Nagamine T,Satoh T,Ohkubo T,Yokoyama A,Ishii Y,Kamiya T,Arakawa K,Makino S,Utsugi M,Ishizuka T,Tanaka S,Shimizu K,Mori M

更新日期：2010-01-01 00:00:00

abstract：:We describe the case of a 30-year-old female with no family history of psoriasis and suffering from Crohn's disease successfully treated with infliximab at the dosage of 5 mg/kg. On the 15th week from the start of therapy, the patient developed a palmoplantar pustular psoriasis, which spread to the arms, trunk and sca...

journal_title：International journal of immunopathology and pharmacology

authors： Manni E,Barachini P

更新日期：2009-07-01 00:00:00

abstract：:Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms a...

journal_title：International journal of immunopathology and pharmacology

authors： Ricciardolo FL,Sorbello V,Silvestri M,Giacomelli M,Debenedetti VM,Malerba M,Ciprandi G,Rossi GA,Rossi A,Bontempelli M

更新日期：2013-01-01 00:00:00

abstract：:Ionizing irradiation causes damage and functional failure of irradiation-sensitive systems and tissues such as small intestine. The molecular mechanisms underlying inflammatory and adaptive responses to acute irradiation damage are poorly understood. Using a mouse model of total-body γ-irradiation, we assessed the irr...

journal_title：International journal of immunopathology and pharmacology

authors： Gorbunov NV,Garrison BR,Kiang JG

更新日期：2010-10-01 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (nCFb) is an acquired condition of variable etiology. An impaired mucociliary clearance seems to be one of the mechanisms behind nCFb, and treatment involves antibiotics, mucoactive agents, and airway clearance techniques (ACTs). Traditional ACTs have four components: postural draina...

journal_title：International journal of immunopathology and pharmacology

authors： Snijders D,Fernandez Dominguez B,Calgaro S,Bertozzi I,Escribano Montaner A,Perilongo G,Barbato A

更新日期：2015-06-01 00:00:00

abstract：:One of the most dangerous possible complications in joint replacement is infection due to bacteria adhere to prosthesis surface making biofilm difficult to erase. The gold standard treatment consists in prosthesis removal, placement of antibiotic-impregnated cement spacer and systemic antibiotics therapy. When the inf...

journal_title：International journal of immunopathology and pharmacology

authors： Zoccali C,Contestabile M,Di Segni S,Nuvoli B,Prencipe U,Erba F

更新日期：2011-01-01 00:00:00

abstract：:There is still no "gold standard" for the diagnosis and prognosis of post-operative periprosthetic joint infection (PJI). Among serum biomarkers, an emerging molecule is presepsin, the soluble fraction of CD14, recently described in other settings as a powerful diagnostic tool to detect sepsis at different degrees of ...

journal_title：International journal of immunopathology and pharmacology

authors： Marazzi MG,Randelli F,Brioschi M,Drago L,Romanò CL,Banfi G,Massaccesi L,Crapanzano C,Morelli F,Corsi Romanelli MM,Galliera E

更新日期：2018-01-01 00:00:00

abstract：:Current therapies against hepatocellular carcinoma (HCC) are not curative in the majority of patients. In the past, immunotherapy approaches aimed to non-specifically stimulate immune response were quite ineffective. New treatments based on stimulation of specific anti-tumor immune response are currently proposed and ...

journal_title：International journal of immunopathology and pharmacology

authors： Rinaldi M,Iurescia S,Fioretti D,Ponzetto A,Carloni G

更新日期：2009-04-01 00:00:00

abstract：:Optimal management of deep infections in orthopedic and trauma surgery is often challenging. Traditional prophylactic and treatment approaches are based on the systemic administration of relatively high doses of antibiotics, which may result in a number of side effects. Furthermore, systemically administered antimicro...

journal_title：International journal of immunopathology and pharmacology

authors： Nizegorodcew T,Palmieri G,Marzetti E

更新日期：2011-01-01 00:00:00

abstract：:Acrodermatitis enteropathic (AE) is a rare autosomal recessive disorder due to a zinc deficiency and characterized by a classical triad of symptoms: dermatitis, alopecia, and diarrhea. The defective gene is SLC39A4, which encodes a zinc transporter. Nevertheless many abnormalities in SLC39A4 have been relieved, only 5...

journal_title：International journal of immunopathology and pharmacology

authors： Ricci G,Ferrari S,Calamelli E,Ricci L,Neri I,Patrizi A

更新日期：2016-06-01 00:00:00

abstract：:Surgical stress induces complex modifications in the hemodynamic, metabolic, neuro-hormonal and immune response of the individual. The magnitude of these alterations depends on preoperative events leading to surgery, the severity of surgical trauma, and also on post-operative/post-traumatic complications (multiple hit...

journal_title：International journal of immunopathology and pharmacology

authors： Cardinale F,Chinellato I,Caimmi S,Peroni DG,Franceschini F,Miraglia Del Giudice M,Bernardini R

更新日期：2011-07-01 00:00:00

abstract：:This study aims to characterize phenotypic and genotypic virulence traits in Escherichia coli strains, isolated from outpatients with urinary tract infections, comparing with those obtained from inpatients. Information on the pathogenic behavior of the uropathogenic strains was obtained by monitoring different biologi...

journal_title：International journal of immunopathology and pharmacology

authors： Longhi C,Cossu A,Iebba V,Massaro MR,Cipriani D,Chiarini F,Conte MP,Seganti L,Osborn J,Schippa S

更新日期：2008-07-01 00:00:00

abstract：:Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia. Recently, we demonstrated that microvesicles (MVs) derived from EPCs are able to activate an angiogenic program in quiescent endothelial cells by a horizontal transfer of RNA. In this study...

journal_title：International journal of immunopathology and pharmacology

authors： Ranghino A,Cantaluppi V,Grange C,Vitillo L,Fop F,Biancone L,Deregibus MC,Tetta C,Segoloni GP,Camussi G

更新日期：2012-01-01 00:00:00

abstract：:Nickel (Ni) oral hyposensitization treatment (NiOHT) is an effective management approach for Ni allergy. No health-related quality of life (HRQoL) data exist for the pre- and post-treatment with NiOHT in systemic nickel allergy syndrome (SNAS). The aims of this study were (a) to explore HRQoL in SNAS patients, (b) to ...

journal_title：International journal of immunopathology and pharmacology

authors： Rizzi A,Di Rienzo A,Buonomo A,Aruanno A,Carusi V,Ricci AG,Centrone M,Mezzacappa S,Romeo L,Schiavino D,Inchingolo R,Gasbarrini A,Nucera E

更新日期：2020-01-01 00:00:00

abstract：:Pseudoxanthoma Elasticum-like Papillary Dermal Elastolysis (PXE-PDE) is a peculiar idiopathic elastolytic disorder that clinically resembles Psudoxanthoma elasticum(PXE). It is histologically characterized by a total or partial loss of elastic fibers in the papillary dermis. It more often affects elderly women and is ...

journal_title：International journal of immunopathology and pharmacology

authors： Pranteda G,Muscianese M,Marmo G,Fidanza L,Pranteda G,Tamburi F,Bottoni U,Nisticò S

更新日期：2013-10-01 00:00:00

abstract：:The development and growth of the rat heart implies hyperplasia, which stops at birth, and hypertrophy, allowing cardiac mass to grow in response to programmed genetic events along with to haemodynamic overload. Moreover, hypertrophy is accomplished to apoptosis which controls the final number of myocardial cells, del...

journal_title：International journal of immunopathology and pharmacology

authors： Centurione L,Di Giulio C,Santavenere E,Cacchio M,Sabatini N,Rapino C,Bianchi G,Rapino M,Bosco D,Antonucci A,Cataldi A

更新日期：2005-01-01 00:00:00

abstract：:Blockade of the interactions between CD28/CTLA-4 and their ligands, CD80 (B7, B7.1)/CD86 (B70, B7.2), is an attractive means to induce antigen-specific peripheral tolerance in autoimmune disease and organ transplantation. In this study, we generated and characterized a monoclonal antibody (Clone 4E5) against human CD8...

journal_title：International journal of immunopathology and pharmacology

authors： Shi Q,Gao ZY,Xie F,Wang LF,Gu YP,Yang TJ,Huang L,Qian QH,Qiu YH

更新日期：2011-07-01 00:00:00

abstract：:We reported a case of an 11-year-old girl admitted to our hospital for goiter, tachycardia, sweating, and visible and palpable thyroid. Thyroid function tests revealed a low thyrotropin level (<0.004 mIU/L) and elevated free thyroxine level (3.4 ng/ dL) diagnosed with Graves' disease and treated with methimazole. This...

journal_title：International journal of immunopathology and pharmacology

authors： Arrigo T,Cutroneo PM,Vaccaro M,Impollonia D,Squadrito V,Mecchio A,Salpietro C,Altavilla D

更新日期：2016-12-01 00:00:00

abstract：:Type 1 diabetes (T1D) is a heterogeneous disorder characterized by destruction of pancreatic beta cells, culminating in loss of insulin secretion. Data from large epidemiologic studies worldwide indicate that during the last decades the incidence of T1D has increased significantly, reaching percentages of 2-5% annuall...

journal_title：International journal of immunopathology and pharmacology

authors： Piccini B,Toni S,Lenzi L,Guasti M,Barni F,De Martino M

更新日期：2012-04-01 00:00:00