Abstract:
BACKGROUND:Disproportionate short stature may impair the quality of life (QoL) of patients and their families. This study aimed to evaluate a self-help supported counseling concept to increase the QoL of the participants. METHODS:QoL data from 58 children/adolescents (8-17 years) with a diagnosis of achondroplasia was collected at 2 measurement points during one year using the the QoLISSY questionnaire (self-/parental report). Differences before and after participation vs. non-participation in the intervention were evaluated using a linear mixed model. RESULTS:The longitudinal results show a greater increase of QoL in the active intervention group compared to a passive control group (p=0,005). The increase in the self-reported QoL of affected patients was significantly higher than for the parent-report (p=0,048). CONCLUSIONS:The study shows that patients with achondroplasia benefit from a self-help supported counseling concept. However, this should be tested in a randomized trial.
journal_name
Klin Padiatrjournal_title
Klinische Padiatrieauthors
Rohenkohl AC,Sommer R,Kahrs S,Bullinger M,Klingebiel KH,Quitmann JHdoi
10.1055/s-0035-1564106subject
Has Abstractpub_date
2016-01-01 00:00:00pages
17-23issue
1eissn
0300-8630issn
1439-3824journal_volume
228pub_type
杂志文章abstract::Prolactin levels were measured immediately after the seizure in some, and 15 to 20 minutes later in all of 67 children aged between 6 months and 17 years. Values were determined after grand mal, complex partial and petit mal seizures and psychogen seizures. A more than 2 to 3 fold prolactin increase over the baseline ...
journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:10.1055/s-2007-1025341
更新日期:1992-05-01 00:00:00
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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abstract::A case of true hermaphroditism was described. The patient had an uterus, a fallopian tube, a testide on the left in the position of the ovary and an ovary on the right side. The chromosome picture corresponded to a 47, XXY/46, XX/46 XXY mosaic. The phenotype of the patient was male so the decision for male sex seemed ...
journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:
更新日期:1976-09-01 00:00:00
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:10.1055/a-1158-9341
更新日期:2020-11-01 00:00:00
abstract::15 parameters of coagulation and fibrinolysis were investigated in 38 children with type I diabetes mellitus without clinical signs of diabetic angiopathy. Compared to an age matched non diabetic control group spontaneous platelet aggregation was enhanced, plasma levels for factor VIII C, von Willebrand factor, antith...
journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:10.1055/s-2007-1025468
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:The aim of most of the trials of the Competence Network Malignant Lymphoma is to optimize the standard treatment of lymphoma using only registered drugs in the case of medicinal therapies (quality assurance protocols). In contrast to regulatory trials, special regulations for quality assurance protocols are ...
journal_title:Klinische Padiatrie
pub_type: 杂志文章
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更新日期:2003-11-01 00:00:00
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:10.1055/s-2007-1025295
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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更新日期:2000-05-01 00:00:00
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章,评审
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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更新日期:2008-11-01 00:00:00
abstract::Important polymorphonuclear leukocyte (PMN) functions are dependent on an intact cytoskeleton, consistent of the microtubulus and microfilament system. This can be assayed from the mobility of fluorescence labelled Concanavalin A (Con A) receptor complexes on the cell surface. Con A shows an uniform surface distributi...
journal_title:Klinische Padiatrie
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Klinische Padiatrie
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更新日期:2016-07-01 00:00:00
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:Klinische Padiatrie
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更新日期:2006-01-01 00:00:00
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
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更新日期:1995-11-01 00:00:00
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:1991-07-01 00:00:00
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:10.1055/a-1202-1758
更新日期:2021-01-01 00:00:00