Abstract:
INTRODUCTION:Gender dysphoria (GD) in childhood and adolescence is characterized by an incongruence between sex at birth and gender identity, which usually increases during puberty. Gender dysphoric children and adolescents often suffer from psychological comorbidities such as depression. The purpose of our study is to give an overview of the patients treated in our clinic. METHODS:We analyzed data of 66 patients who presented with GD at our outpatient clinic between 2005 and 2018. RESULTS:We noted a rise of presentations with one or no patient with GD per year between 2005 and 2008 up to 18 patients in 2018, although the percentage of all 14.339 endocrinological outpatients (2005-2018) is low. 54 patients were assigned as female and 12 as male at birth resulting in a ratio of 4.5:1. The mean age at their first appointment was 13.6 years. 49 patients (74%) had reached tanner stadium P3/B3 or P3/G3. 30 (45%) showed symptoms of a comorbidity related to GD. 48 (73%) showed symptoms of GD before puberty. 15 patients (23%) experienced a negative response regarding their outing and 17 (26%) were victims of mobbing in school. CONCLUSION:The number of patients increased in the last years. About half of the patients suffered from a psychological comorbidity. They often experienced negative response regarding their GD in the family. The variability of appearance and the comorbidities pose the challenge in the treatment of gender dysphoric children and adolescents. EINLEITUNG:Die Geschlechtsdysphorie im Kindes- und Jugendalter (GD) zeigt sich durch eine Inkongruenz zwischen dem Geburtsgeschlecht und der gefühlten Geschlechtsidentität, welche in der Regel in der Pubertät zunimmt. Kinder und Jugendliche mit GD sind häufiger von psychischen Komorbiditäten wie Depressionen betroffen. Diese Arbeit soll einen Überblick über die von uns behandelten Patienten geben. METHODEN:Es erfolgte eine Datenanalyse aus den Patientenakten von 66 Patienten, welche sich im Zeitraum von 2005 bis 2018 erstmals mit einer GD in unserer endokrinologischen Ambulanz vorstellten. ERGEBNISSE:Wir beobachteten einen Anstieg der Neuvorstellungen von maximal einem Patienten pro Jahr zwischen 2005 und 2011 auf zuletzt 18 Neuvorstellungen im Jahr 2018, wobei der Anteil an den insgesamt 14 339 endokrinologischen Patienten desselben Zeitraums mit 0,49% gering ist. 54 der Patienten hatten ein weibliches und 12 ein männliches Geburtsgeschlecht, damit lag das Geschlechterverhältnis bei 4,5:1. Das Durchschnittsalter bei Erstvorstellung betrug 13,6 Jahre. 49 Patienten (74%) überschritten das Pubertätsstadium P3/B3 bzw. P3/G3 nach Tanner. 48 (73%) entwickelten erste Symptome einer GD vor der Pubertät und 30 (45%) zeigten eine psychische Komorbidität. 15 Patienten (23%) berichteten über negative Reaktionen ihres sozialen Umfelds nach ihrem Outing und 17 (26%) machten Erfahrung mit Mobbing in der Schule. SCHLUSSFOLGERUNG:Die Patientenzahl von Kindern und Jugendlichen mit GD ist in den letzten Jahren deutlich gestiegen. Zusätzlich zu der psychischen Belastung aufgrund der GD konnten wir bei ungefähr der Hälfte der Patienten typische psychische Komorbiditäten einer GD feststellen. Außerdem berichten Kinder und Jugendliche von negativen Reaktionen bezüglich ihrer GD in der Schule und der Familie. Die hohe Variabilität des Verlaufs und der Komorbiditäten stellt die zentrale Herausforderung in der Therapie dar.
journal_name
Klin Padiatrjournal_title
Klinische Padiatrieauthors
Specht AA,Gesing J,Pfaeffle R,Koerner A,Kiess Wdoi
10.1055/a-1066-4625subject
Has Abstractpub_date
2020-01-01 00:00:00pages
5-12issue
1eissn
0300-8630issn
1439-3824journal_volume
232pub_type
杂志文章,评审abstract::Since 1962, desferrioxamine (deferoxamine, DFO) has been utilized for the treatment of secondary hemosiderosis. For about 30 years, DFO therapy has been performed as nightly continuous subcutaneous infusion. About 20 years ago, the first oral iron chelator (deferiprone, DFP) was presented. Concerns about potential sid...
journal_title:Klinische Padiatrie
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abstract::Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...
journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章,评审
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abstract::From 1968--1978 a longitudinal study was performed concerning development of thorax, upper arm, thigh and calf circumferences in 709 boys and 711 girls 2--15 years old. In boys the mean increase in thoracic circumference amounted to 32.9 cm, in upper are circumference to 8.3 cm, in thigh circumference to 20.6 cm and i...
journal_title:Klinische Padiatrie
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abstract::A case of arteriovenous aneurysm of the great vein of Galen with congestive heart failure in a newborn infant is presented. Efficiancy of medical management and stop of growth of the head circumference point towards a good prognosis. Patients with this malformation have been divided into four clinical groups presentin...
journal_title:Klinische Padiatrie
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abstract:BACKGROUND:Most patients with terminal renal failure show arterial hypertension. In addition to casual blood pressure measurements in the clinic, home blood pressure measurement is recommended for these patients to control arterial blood pressure. PATIENTS:The study was performed in children with hemodialysis (HD; n =...
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abstract::Positive anti-DNA-antibodies and lowered C3 and C4 levels were found in serum of a 13 year old girl presenting with edema, microscopic hematuria and proteinuria. Renal biopsy revealed diffuse endo- and extracapillary glomerulonephritis with mesangial deposits of IgA, IgG, IgM, C1q, C3 and fibrinogen. In spite of treat...
journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
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journal_title:Klinische Padiatrie
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journal_title:Klinische Padiatrie
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Klinische Padiatrie
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
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journal_title:Klinische Padiatrie
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