[Immune granulocytopenia in children].

abstract：:The diagnosis of HFI is easily missed during childhood. It should be suspected in children presenting with hepatomegaly and an isolated increase in GGT. A carefully taken nutritional history forms the basis of the diagnosis of HFI which can be confirmed by molecular analysis with a sensitivity of > 95%. I.v. fructose ...

journal_title：Klinische Padiatrie

authors： Wössmann W,Wiemann J,Körber F,Gortner L

更新日期：2000-05-01 00:00:00

abstract：:Problems of terminology, differential diagnosis, etiology and therapy of language development disorders are demonstrated by a casuistic example. Besides the importance of clinical date special attention was laid on neuropsychological diagnostic procedures and their therapeutic implications. Therapeutic interventions c...

journal_title：Klinische Padiatrie

authors： Niebergall G,Wiesse J

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:There is a subgroup of pediatric patients with an immature immunophenotype of proB-ALL that still poses a therapeutic challenge, even if the overall prognosis in B cell precursor acute lymphoblasic leukemia (BCP-ALL) is very good. Due to impaired treatment response these patients are prone to suffer relapse ...

journal_title：Klinische Padiatrie

authors： Troeger A,Glouchkova L,Escherich G,Siepermann M,Hanenberg H,Janka-Schaub G,Göbel U,Ackermann B,Dilloo D

更新日期：2008-11-01 00:00:00

abstract：:Female patients with anorexia nervosa (a.n.) are characterized by distinct endocrine features probably due to hypothalamic pituitary dysfunctions. There is only a limited number of case reports available on patients with a.n.; mostly with few data on hormones. In six male patients with a.n. we examined basal and stimu...

journal_title：Klinische Padiatrie

authors： Toifl K,Waldhauser F,Lischka A,Frisch H

更新日期：1988-07-01 00:00:00

abstract：:Growing teratoma is still an often unsolved problem especially in male with mixed malignant GCTs of the testis or the mediastinum. This specific situation with progressive tumor growth and simultaneous normalization of tumor markers during or after treatment of malignant GCTs with teratomatous elements is judged as a ...

journal_title：Klinische Padiatrie

authors： Calaminus G,Schneider DT,Weissbach L,Schönberger S,Okpanyi V,Leuschner I,Poremba C,Göbel U

更新日期：2009-05-01 00:00:00

abstract：:The aims of trial NHL-BFM 90 for patients (pts) suffering from B-cell neoplasms are to prove whether: 1. Treatment for pts with complete resection can be reduced from 3 to 2 therapy courses; 2. Results for pts of stage III with large abdominal tumors can be improved by high dose (HD) chemotherapy; 3. Survival for pts ...

journal_title：Klinische Padiatrie

authors： Reiter A,Schrappe M,Yakisan E,Sauter S,Ebell W,Zimmermann M,Hartmann W,Kremens B,Kuhn N,Claviez A

更新日期：1994-07-01 00:00:00

abstract：:In our experience the prognosis of hematological relapse in patients with acute lymphatic leukemia treated according to the Pinkel programme is very bad. It may be a little better for patients in whom relapse occurred after the end of therapy and who were submitted to intensified cytostatic treatment. The chances for ...

journal_title：Klinische Padiatrie

authors： Gröbe H,Schellong G

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Modern neonatal and pediatric intensive care includes a sophisticated pharmacotherapy with numerous drugs, mainly administered intravenously. Often, despite the use of multi-lumen central venous lines, more peripheral venous accesses are required. To reduce the necessity of numerous venous lines on one hand ...

journal_title：Klinische Padiatrie

authors： Höpner JH,Schulte A,Thiessen J,Knuf M,Huth RG

更新日期：2007-01-01 00:00:00

abstract：:Evoked otoacoustic emissions (EOAE) and brainstem acoustic evoked potentials (BAEP) were recorded from 78 children following neonatal intensive care. In 23% no EOAE could be obtained. Hearing impairment in the BAEP was found in 9%. In 22% negative EOAE were found in spite of normal BAEP. According to the latency-inten...

journal_title：Klinische Padiatrie

authors： Lauffer H,Pröschel U,Gerling S,Wenzel D

更新日期：1994-03-01 00:00:00

abstract：:Waardenburg syndrome Type I is described on the basis of an observation of a family. The characteristic signs including lateral displacement of medial canthi ("telecanthus"), wide bridge of the nose, white forelock and severe cochlear deafness are found in one female patient only; however, her eyes are not of differen...

journal_title：Klinische Padiatrie

authors： Meinecke P

更新日期：1982-03-01 00:00:00

abstract：:Report of a case with congenital right sided intrapericardial diaphragmatic hernia. This type of a congenital diaphragmatic hernia occurs only rarely. Until 1984 30 cases are recorded in the available literature. ...

journal_title：Klinische Padiatrie

authors： Langer R,Kaufmann HJ

更新日期：1986-07-01 00:00:00

abstract：:A congenital diverticulum of the ventricle is a very rare cardiac lesion which is almost always associated with additional cardiovascular anomalies. In the majority of cases a diverticulum of the heart has been diagnosed during cardiac catheterization for evaluation of additional cardiovascular anomalies. We report no...

journal_title：Klinische Padiatrie

authors： Wild F,Hofbeck M,Singer H,Hammersen G

更新日期：1993-05-01 00:00:00

abstract：:A multi-center retrospective survey was conducted to evaluate the incidence and types of hemostatic complications occurring in children with acute lymphoblastic leukemia (ALL) during treatment according to the ALL-BFM-90 treatment protocol. All of the BFM-treatment centers (n = 77) were approached and a 95% response r...

journal_title：Klinische Padiatrie

authors： Sutor AH,Mall V,Thomas KB

更新日期：1999-07-01 00:00:00

abstract：:We identified betulinic acid (BetA) as a new cytotoxic agent active against neuroectodermal tumor cells including neuroblastoma, medulloblastoma, glioblastoma and Ewing's sarcoma cells representing the most common solid tumors of childhood. BetA induced apoptosis independent of wild-type p53 protein and accumulation o...

journal_title：Klinische Padiatrie

authors： Fulda S,Jeremias I,Pietsch T,Debatin KM

更新日期：1999-07-01 00:00:00

abstract：:Serum IgA deficiency was first noted in a 10 year old boy 8 months after the onset of D-penicillamine therapy. Special immunological examinations revealed a deficiency of the secretory component of IgA while cellular functions of T- and B-lymphocytes were normal. The patient showed discrete clinical signs compatible w...

journal_title：Klinische Padiatrie

authors： Ibel H,Feist D,Endres W,Belohradsky BH

更新日期：1990-11-01 00:00:00

abstract：:The normal values of the LH and FSH excretion in 12-h-overnight-urine-samples were measured by the commercial technique for the estimation of LH (Luteonosticon) and FSH (FSH-nosticon). These methods were used to determine the hormone excretion of these hormones in healthy individuals, 94 boys (0-18 years) and 48 girls...

journal_title：Klinische Padiatrie

authors： Bressensdorf DB,Knorr D

更新日期：1978-07-01 00:00:00

abstract：:Iron concentration was determined by the aid of the ESA Ferrochem 3050 analyzer and the bathophenanthroline method with deproteinization. Both methods showed a good precision and accuracy. The investigation was carried out in 505 sera with an iron concentration between 9 and 333 micrograms/dl. The comparison of the tw...

journal_title：Klinische Padiatrie

authors： Liappis N

更新日期：1982-01-01 00:00:00

abstract：:From 1975-1986 6 boys with congenital nephrogenic diabetes insipidus were diagnosed at the age of 3 months to 10 years. Symptoms appeared within the first few weeks of life. The diagnosis was confirmed by polyuria, low urinary osmolality (97-225 mosm/kg H20), hypernatraemia (max. 171 mmol/l) and the missing response t...

journal_title：Klinische Padiatrie

authors： Kaulitz R,Brodehl J

更新日期：1989-11-01 00:00:00

abstract：:Mucoid impaction and plastic bronchitis are relatively rare disorders affecting patients of any age. Here we report the case of mucoid impaction developing in a four-year-old child as a complication of pneumonic infection treated four weeks prior. p.a. chest X-ray and fiberoptic bronchoscopy showed atelectasis and the...

journal_title：Klinische Padiatrie

authors： Kamin W,Klär-Hlawatsch B,Truebel H

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:One of the strongest predictive factors for therapy outcome in childhood acute lymphoblastic leukaemia (ALL), treated according to ALL-BFM protocols, is the response to initial prednisone treatment. Prednisone response is characterized by the peripheral leukaemic blast count. The threshold value for the char...

journal_title：Klinische Padiatrie

authors： Lauten M,Stanulla M,Zimmermann M,Welte K,Riehm H,Schrappe M

更新日期：2001-07-01 00:00:00

abstract：:We analyzed episodes of peritonitis and/or sepsis associated with the idiopathic nephrotic syndrome (ns) in 23 children treated between 1975 and 1985 at our clinic. 37.5% of the children with infantile ns, 16% of those with steroidsensible ns, and 13.6% of those with steroidresistant ns developed peritonitis. Children...

journal_title：Klinische Padiatrie

authors： Feldhoff C,Kleine L,Bachmann H

更新日期：1988-01-01 00:00:00

abstract：:Infectious heart diseases in childhood are--with less than 1% of hospital admissions--rare, but serious diseases. Among several causes of myocarditis in our region virus myocarditis plays the most important role. Besides of the acute course an autoimmune mediated chronic myocarditis and the transition to dilated cardi...

journal_title：Klinische Padiatrie

authors： Schmaltz AA

更新日期：1991-01-01 00:00:00

abstract：:Transfusion-induced hemochromatosis remains a major therapeutic complication in the management of patients with chronic hemolytic anemias. Red cell units harvested with blood cell separators have an average estimated mean cell age of 30 days, compared to 60 days for unfractionated blood. Our initial experience with tr...

journal_title：Klinische Padiatrie

authors： Heim MU,Eckstein R,Mittermüller H,Haas RJ,Schmidt P,Graebner E,Pape W,Mempel W

更新日期：1985-03-01 00:00:00

abstract：:An increasing number of children with acute leukemia show cerebral complications. 10 out of 78 children treated in our hospital for acute lymphoblastic leukemia or non-Hodgkin's lymphoma who underwent remission induction therapy or were in continuous complete remission developed central nervous system complications. D...

journal_title：Klinische Padiatrie

authors： Ludwig R,Meyer E,Brandeis WE

更新日期：1980-07-01 00:00:00

abstract：:An eight-year old girl showing a X/X-translocation (45,X/46,Xt(X;X)(q26;p11)) is presented. Besides short stature and congenital heart-anomaly no other phenotypical abnormalities were present. In all cells containing the abnormal X-chromosome, the latter was late labeling as shown by autoradiography and BrdU-labeling....

journal_title：Klinische Padiatrie

authors： Wagenbichler P,Frisch H,Schnedl W

更新日期：1975-11-01 00:00:00

abstract：:Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...

journal_title：Klinische Padiatrie

authors： Uhlenbruck G,Scheuring U,Dienst C,Kaiser D,Roth B,Skopnik H

更新日期：1988-03-01 00:00:00

abstract：:The integration of colleagues from psychosocial occupations into the traditional team of doctors and nurses demands a holistic treatment concept, the general desire for interdisciplinary action, and readiness for patience in the process of mutual learning. The acceptance of the psychosocial services by the patient and...

journal_title：Klinische Padiatrie

authors： Janssen F

更新日期：1989-07-01 00:00:00

abstract：:While leadpoisoning has been with mankind since the dawn of civilization, only in recent years this disease was recognized as a serious public health problem. It has been estimated that more than half a million children are suffering from lead intoxication in the U.S.A. In most instances this disease is caused by eati...

journal_title：Klinische Padiatrie

authors： Püschel SM

更新日期：1975-09-01 00:00:00

abstract：:The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither...

journal_title：Klinische Padiatrie

authors： Schneppenheim R,Rautenberg P,Behnke H,Vietor K

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Neurotrophins and their cognate receptors TrkA, TrkB and TrkC regulate proliferation, differentiation and death of neuronal progenitor cells and may be implicated in the progression of medulloblastoma and other primitive neuroectodermal brain tumors (PNET). These common childhood brain tumors are composed of...

journal_title：Klinische Padiatrie

authors： Grotzer MA,Janss AJ,Phillips PC,Trojanowski JQ

更新日期：2000-07-01 00:00:00