[Progress in the therapy of children with congenital hemolytic anemias by transfusion of neocyte concentrations. Initial experiences in the separation and transfusion of young erythrocytes, obtained with the cell separator Fenwal CS-3000].

abstract：BACKGROUND:Modern neonatal and pediatric intensive care includes a sophisticated pharmacotherapy with numerous drugs, mainly administered intravenously. Often, despite the use of multi-lumen central venous lines, more peripheral venous accesses are required. To reduce the necessity of numerous venous lines on one hand ...

journal_title：Klinische Padiatrie

authors： Höpner JH,Schulte A,Thiessen J,Knuf M,Huth RG

更新日期：2007-01-01 00:00:00

abstract：:A multi-center retrospective survey was conducted to evaluate the incidence and types of hemostatic complications occurring in children with acute lymphoblastic leukemia (ALL) during treatment according to the ALL-BFM-90 treatment protocol. All of the BFM-treatment centers (n = 77) were approached and a 95% response r...

journal_title：Klinische Padiatrie

authors： Sutor AH,Mall V,Thomas KB

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Epidemiology and resistance patterns of bacterial pathogens in pediatric UTI show large interregional variability and rates of bacterial resistances are changing due to different antibiotic treatment. We intended to evaluate data from northern Germany. PATIENTS AND METHODS:In 100 children (53 female, 47 mal...

journal_title：Klinische Padiatrie

authors： Pape L,Gunzer F,Ziesing S,Pape A,Offner G,Ehrich JH

更新日期：2004-03-01 00:00:00

abstract：:The following paper is the manuscript of an oral presentation during the annual GPOH meeting on May 22nd, 2000 in Berlin. Following her experiences as a member of the psychosocial care team of a children's cancer unit the author discusses the emotional impact of stemcell or bone marrow transplantation in children. Psy...

journal_title：Klinische Padiatrie

authors： Griessmeier B

更新日期：2001-07-01 00:00:00

abstract：:We report of an previously unpublished combination of partial trisomy 9 and a membranous pulmonary atresia with a large conotruncal ventricular septal defect. The dystrophic female, term newborn presented after delivery with microcephaly, prominent nose and several other facial and skeletal deformities. The echocardio...

journal_title：Klinische Padiatrie

authors： Nekarda T,Kececioglu D,Kehl HG,Gehrmann J,Miny P,Vogt J

更新日期：1997-05-01 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) is the most common neurocutaneous disease. The clinical manifestations are diverse. Some of the skeletal changes are most relevant to the patient. We report on 9 patients with NF1 who presented with typical pseudarthrosis. In 8 of these children the lower extremity was involved. In 2 cas...

journal_title：Klinische Padiatrie

authors： Ramelli GP,Slongo T,Weis J,Tschäppler H,Vassella F

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:There is a subgroup of pediatric patients with an immature immunophenotype of proB-ALL that still poses a therapeutic challenge, even if the overall prognosis in B cell precursor acute lymphoblasic leukemia (BCP-ALL) is very good. Due to impaired treatment response these patients are prone to suffer relapse ...

journal_title：Klinische Padiatrie

authors： Troeger A,Glouchkova L,Escherich G,Siepermann M,Hanenberg H,Janka-Schaub G,Göbel U,Ackermann B,Dilloo D

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Thyroglossal duct cysts arise from mucus production in an incomplete regressed thyroglossal duct. Often they are only noticed in case of infection or secondary fistulation. The operative management is a Sistrunk procedure. METHOD AND PATIENTS:In a retrospective study we analyse 26 patients aged 0,3 - 10 yea...

journal_title：Klinische Padiatrie

authors： von Bismarck S,Höllwarth ME

更新日期：2001-09-01 00:00:00

abstract：:Die Fortschritte der molekularen Diagnostik haben neue Türen für die Diagnosestellung, Risikostratifizierung und Präzisionsonkologie für Kinder mit Hirntumoren aufgestoßen. Dieses Wissen konsequent und systematisch in einen klinischen Nutzen zu übertragen wird Aufgabe der kommenden Jahre sein. ...

journal_title：Klinische Padiatrie

authors： Milde T,Witt O

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:One of the strongest predictive factors for therapy outcome in childhood acute lymphoblastic leukaemia (ALL), treated according to ALL-BFM protocols, is the response to initial prednisone treatment. Prednisone response is characterized by the peripheral leukaemic blast count. The threshold value for the char...

journal_title：Klinische Padiatrie

authors： Lauten M,Stanulla M,Zimmermann M,Welte K,Riehm H,Schrappe M

更新日期：2001-07-01 00:00:00

abstract：:Pre- and retrorenal growing neuroblastomas did not produce any displacement of the kidney or any obstruction in the intravenous pyelogram. The diagnosis was done by ultrasound-scanning as well as biochemically before surgery. The reported cases show that sonography and determination of the catecholamine metabolites ar...

journal_title：Klinische Padiatrie

authors： Burdach SE,Bliesener JA,Evers KG,Gharib M

更新日期：1983-01-01 00:00:00

abstract：STUDY OBJECTIVE:This study prospectively investigated the outpatient once daily therapy with ceftriaxone alone or if necessary in combination with teicoplanin, in the treatment of infections in children and adolescents with chemotherapy-induced neutropenia or aplastic anemia. PATIENTS:42 patients 1-22 years of age suf...

journal_title：Klinische Padiatrie

authors： Preis S,Jürgens H,Friedland C,Oudekotte-David AA,Thomas L,Göbel U

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Pachyonychia congenita is considered to be a genodermatosis of autosomal inheritance. It is characterized by nail hypertrophy, shortly present after birth. Later on follicular keratosis of the extremities and hyperkeratosis of palms and soles can be found. HISTORY AND CLINICAL FINDINGS:We report a child wit...

journal_title：Klinische Padiatrie

authors： Wimmershoff MB,Stolz W,Schiffner R,Landthaler M

更新日期：1999-05-01 00:00:00

abstract：:In 24 patients at risk for SIDS (12 infants with a near miss event and 12 infants with apnea and perioral cyanosis during sleep) respiratory and esophageal function were investigated by impedance pneumography (IP) and esophageal manometry combined with simultaneous pH-monitoring (EMPH). Both groups had ad early pathol...

journal_title：Klinische Padiatrie

authors： Landler U,Höllwarth ME,Uray E,Schober PH,Reiterer F,Schenkeli R

更新日期：1990-01-01 00:00:00

abstract：:We analyzed episodes of peritonitis and/or sepsis associated with the idiopathic nephrotic syndrome (ns) in 23 children treated between 1975 and 1985 at our clinic. 37.5% of the children with infantile ns, 16% of those with steroidsensible ns, and 13.6% of those with steroidresistant ns developed peritonitis. Children...

journal_title：Klinische Padiatrie

authors： Feldhoff C,Kleine L,Bachmann H

更新日期：1988-01-01 00:00:00

abstract：UNLABELLED:After corrective surgery for congenital heart defects (CHD) many patients suffer from residual defects, some with reduced cardiorespiratory capacity and possible impairment of their health related quality of life (HRQoL). The aim of our study is to evaluate, how children after surgery for CHD rate their HRQo...

journal_title：Klinische Padiatrie

authors： Heusch A,Calaminus G,Kahl J,Schmidt K

更新日期：2014-09-01 00:00:00

abstract：:Waardenburg syndrome Type I is described on the basis of an observation of a family. The characteristic signs including lateral displacement of medial canthi ("telecanthus"), wide bridge of the nose, white forelock and severe cochlear deafness are found in one female patient only; however, her eyes are not of differen...

journal_title：Klinische Padiatrie

authors： Meinecke P

更新日期：1982-03-01 00:00:00

abstract：:Serum IgA deficiency was first noted in a 10 year old boy 8 months after the onset of D-penicillamine therapy. Special immunological examinations revealed a deficiency of the secretory component of IgA while cellular functions of T- and B-lymphocytes were normal. The patient showed discrete clinical signs compatible w...

journal_title：Klinische Padiatrie

authors： Ibel H,Feist D,Endres W,Belohradsky BH

更新日期：1990-11-01 00:00:00

abstract：:The phagocytic and NBT reduction indices of 94 preterm and underweight babies, divided into 7 groups and two weight classes, were observed over a period of six weeks while they were observed over a period of six weeks while they were given four commercial baby foods (Humana 0, Meb, Multival, Pomil). In all groups the ...

journal_title：Klinische Padiatrie

authors： Jeschke R,Ströder J

更新日期：1978-03-01 00:00:00

abstract：:Neurofibromatosis type 1 is the most common of the phakomatoses and the clinical follow-up is an interdisciplinary challenge. The data of 27 patients with NF1 were systematically reviewed and compared to data from the literature. All of our patients had clinical signs of NF1. Besides the classic criteria café-au-lait ...

journal_title：Klinische Padiatrie

authors： Syrbe S,Eberle K,Strenge S,Bernhard MK,Herbertz S,Bierbach U,Hirsch W,Froster UG,Kiess W,Merkenschlager A

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Surveys in USA and UK have shown inconsistencies between practice of sweat testing and guidelines of the National Committee for Clinical Laboratory Standards (NCCLS), which could increase the risk of false-positive and -negative results. To determine the current practice of sweat testing in German cystic fib...

journal_title：Klinische Padiatrie

authors： Naehrlich L

更新日期：2007-03-01 00:00:00

abstract：:5 patients 10 to 20 months old with severe normochromic, normocytic anemia and reticulocytopenia are reported. All patients recovered within 10 days to 5 weeks. No steroid therapy was given. Failure to recognize the clinical entity leads to unnecessary diagnostic and therapeutic procedures including the transfusion of...

journal_title：Klinische Padiatrie

authors： Schneider H,Jobke A,Niederhoff H,Künzer W

更新日期：1985-01-01 00:00:00

abstract：:The paper reported about septicaemia in the neonatal and infant period. Continuing former investigations by Kienitz in the same pediatric clinic we have got a survey from 1933 to 1974. In the last years we saw increasingly more infections with gram-negative organisms, especially by Pyocyaneus with a severe prognosis. ...

journal_title：Klinische Padiatrie

authors： Diekmann L,Kotzur J

更新日期：1976-03-01 00:00:00

abstract：UNLABELLED:We present updated results of stem cell transplantation with highly purified stem cells from haploidentical parental donors and infection with human adenovirus (HAdV) post stem cell transplantation (SCT). Survival post SCT is primarily determined by relapse, infections and far less by GvHD or other transplan...

journal_title：Klinische Padiatrie

authors： Feuchtinger T,Richard C,Pfeiffer M,Neuhäuser F,Lücke J,Handgretinger R,Greil J,Bader P,Klingebiel T,Schlegel PG,Jahn G,Niethammer D,Lang P

更新日期：2005-11-01 00:00:00

abstract：:Report of a case of the fetal face syndrome associated with severe oligophrenia and septum pellucidum cyste in a male patient aged 30 years. The case demonstrates the good prognosis of the hypogenitalism resp. small genitalia; the correct diagnosis in this syndrome can the patients save a plastic of the penis. ...

journal_title：Klinische Padiatrie

authors： Fehlow P,Walther F,Pfeifer T,Schuchard UM

更新日期：1995-11-01 00:00:00

abstract：:During the last 6 years 73 previously untreated children and adolescents with acute lymphoblastic leukemia were enrolled on a non-randomized therapy protocol. In this longitudinal study the specific accent was put on the intensified induction treatment of 8 weeks' duration which was thought to achieve a higher remissi...

journal_title：Klinische Padiatrie

authors： Riehm H,Gadner H,Welte K

更新日期：2013-05-01 00:00:00

abstract：:Glutaracidemia/glutaraciduria type I is an acute or subacute neuropathic disorder of infancy or early childhood. The following symptoms characterize the clinical course: macrocephalus present at birth, cerebral atrophy revealed by CT or MRI scans, most striking in the frontal and temporal lobes, choreoathetosis and dy...

journal_title：Klinische Padiatrie

authors： Voll R,Hoffmann GF,Lipinski CG,Trefz FK,Weisser J

更新日期：1993-03-01 00:00:00

abstract：:The normal values of the LH and FSH excretion in 12-h-overnight-urine-samples were measured by the commercial technique for the estimation of LH (Luteonosticon) and FSH (FSH-nosticon). These methods were used to determine the hormone excretion of these hormones in healthy individuals, 94 boys (0-18 years) and 48 girls...

journal_title：Klinische Padiatrie

authors： Bressensdorf DB,Knorr D

更新日期：1978-07-01 00:00:00

abstract：:The psychosocial and intellectual development of 4 boys with nephropathic cystinosis and brain atrophy documented by cranial computerized tomography was investigated by use of biographical data and psychological tests (HAWIK, Deutscher Rechtschreibtest). Inspite of the brain atrophy the patients showed low-normal inte...

journal_title：Klinische Padiatrie

authors： Ehrich JH,Wolff G,Stoeppler L,Heyer R,Offner G,Brodehl J

更新日期：1979-09-01 00:00:00

abstract：:The rapid institution of empirical broad-spectrum antibiotics has become the gold standard of treatment for febrile neutropenic children undergoing therapy for cancer. With this approach, morbidity and mortality have dropped significantly but have not been eliminated altogether. In recent randomized studies evaluating...

journal_title：Klinische Padiatrie

authors： Laws HJ,Ammann RA,Lehrnbecher T

更新日期：2005-11-01 00:00:00