Betulinic acid: a new chemotherapeutic agent in the treatment of neuroectodermal tumors.

abstract：:5 patients 10 to 20 months old with severe normochromic, normocytic anemia and reticulocytopenia are reported. All patients recovered within 10 days to 5 weeks. No steroid therapy was given. Failure to recognize the clinical entity leads to unnecessary diagnostic and therapeutic procedures including the transfusion of...

journal_title：Klinische Padiatrie

authors： Schneider H,Jobke A,Niederhoff H,Künzer W

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:  Despite a reduction in hospitalizations due to acute alcohol intoxication in minors, alcohol consumption among children and adolescents still presents an alarming social and clinical phenomenon. This is amplified by presumably more severe clinical symptoms of the alcohol intoxication in children and adoles...

journal_title：Klinische Padiatrie

authors： Lozada CAQ,Bartels MB,Kieslich M

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:There is a subgroup of pediatric patients with an immature immunophenotype of proB-ALL that still poses a therapeutic challenge, even if the overall prognosis in B cell precursor acute lymphoblasic leukemia (BCP-ALL) is very good. Due to impaired treatment response these patients are prone to suffer relapse ...

journal_title：Klinische Padiatrie

authors： Troeger A,Glouchkova L,Escherich G,Siepermann M,Hanenberg H,Janka-Schaub G,Göbel U,Ackermann B,Dilloo D

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Modern neonatal and pediatric intensive care includes a sophisticated pharmacotherapy with numerous drugs, mainly administered intravenously. Often, despite the use of multi-lumen central venous lines, more peripheral venous accesses are required. To reduce the necessity of numerous venous lines on one hand ...

journal_title：Klinische Padiatrie

authors： Höpner JH,Schulte A,Thiessen J,Knuf M,Huth RG

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Thyroglossal duct cysts arise from mucus production in an incomplete regressed thyroglossal duct. Often they are only noticed in case of infection or secondary fistulation. The operative management is a Sistrunk procedure. METHOD AND PATIENTS:In a retrospective study we analyse 26 patients aged 0,3 - 10 yea...

journal_title：Klinische Padiatrie

authors： von Bismarck S,Höllwarth ME

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Thermal injuries are a frequent cause of accidents within the pediatric population that may result in long periods of hospitalization as well as severe physical and mental impairment and lifelong consequences. Especially in infants, burns caused by scalding are the most common cause of injury. Beside acciden...

journal_title：Klinische Padiatrie

authors： Klinke M,Schmidt CM,Tegtmeyer L,Reinshagen K,Boettcher M,Koenigs I

更新日期：2018-03-01 00:00:00

abstract：:The integration of colleagues from psychosocial occupations into the traditional team of doctors and nurses demands a holistic treatment concept, the general desire for interdisciplinary action, and readiness for patience in the process of mutual learning. The acceptance of the psychosocial services by the patient and...

journal_title：Klinische Padiatrie

authors： Janssen F

更新日期：1989-07-01 00:00:00

abstract：:Inherited disorders of platelets constitute a group of rare diseases that give rise to bleeding syndromes of variety severity, with more severe cases being first diagnosed during infancy and childhood. To appropriate diagnose a platelet function disorder during early childhood the knowledge of the physiological charac...

journal_title：Klinische Padiatrie

authors： Schlegel N,Bardet V,Kenet G,Muntean W,Zieger B,Nowak-Göttl U,Working Group on Standardisation in Perinatal and Pediatric Hemostasis.

更新日期：2010-05-01 00:00:00

abstract：:The oscillatory resistance to respiration (Ros) was measured in 218 children and 260 adults using the Siregnost FD5 (Siemens, Erlangen), and compared with whole body plethysmography (Raw) and with spirometry. There was a markedly better correlation between Ros and Raw (r=0.82;n=88) in children than in adults (r=0.53;n...

journal_title：Klinische Padiatrie

authors： Berdel D,Holle JP,Hartmann V,Magnussen H

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:We wanted improve the nutritional status of patients with cystic fibrosis with enteral feeding via a percutaneous endoscopic gastrostomy (PEG). PATIENTS AND METHODS:In a period of 8 years 11 patients underwent a percutaneous endoscopic gastrostomy (PEG), 4 males and 7 females, in the median 14,9 years of ag...

journal_title：Klinische Padiatrie

authors： Richter T,Meier C,Steppberger K,Knorrek G,Lietz T

更新日期：2001-11-01 00:00:00

abstract：:The German Society of Pediatric Oncology (GPO) designed a cooperative study to improve the outlook of patients with malignant (testicular) germ cell tumors. According to stage and histology of the tumor different surgical approaches to retroperitoneal lymphadenectomy are suggested. Local radiotherapy is not recommende...

journal_title：Klinische Padiatrie

authors： Haas RJ,Brämswig J,Göbel U,Harms D,Janka G,Weissbach L

更新日期：1983-05-01 00:00:00

abstract：UNLABELLED:We present an unusual case of neonatal liver failure. Isolated ascites was diagnosed in a female fetus at week 34 gestational age upon routine ultrasound. In the 35th week of gestation a cesarean section was carried out after puncture of fetal ascites. After birth the patient showed symptoms and complication...

journal_title：Klinische Padiatrie

authors： Keller M,Scholl-Buergi S,Sergi C,Theurl I,Weiss G,Unsinn KM,Trawöger R

更新日期：2008-01-01 00:00:00

abstract：:The pros and cons of home monitoring especially for premature infants with continuing apneic episodes and/or chronic lung disease are an ongoing discussion. The controversy spans socio-economic requirements, medical indication as well as patient and family needs. Here, the costs of home monitoring and follow-up care o...

journal_title：Klinische Padiatrie

authors： Förster KM,Immler S,Ensslen M,Flemmer A,Schulze A,von Poblotzki M,Genzel-Boroviczény O,Heinen F,Hilgendorff A

更新日期：2015-03-01 00:00:00

abstract：:The death of a child after an oncologic disease gives rise to feelings of mourning, loss and anger in family members and often also in oncology team members. All people involved need to find ways of coping with these emotions and thought. Therefore, the oncology team of the Children's Hospital Tuebingen has, for many ...

journal_title：Klinische Padiatrie

authors： Kochendörfer S

更新日期：2002-07-01 00:00:00

abstract：:The aims of trial NHL-BFM 90 for patients (pts) suffering from B-cell neoplasms are to prove whether: 1. Treatment for pts with complete resection can be reduced from 3 to 2 therapy courses; 2. Results for pts of stage III with large abdominal tumors can be improved by high dose (HD) chemotherapy; 3. Survival for pts ...

journal_title：Klinische Padiatrie

authors： Reiter A,Schrappe M,Yakisan E,Sauter S,Ebell W,Zimmermann M,Hartmann W,Kremens B,Kuhn N,Claviez A

更新日期：1994-07-01 00:00:00

abstract：:Hereditary Factor VII deficiency is one of the rare congenital coagulopathies. Prolonged prothrombin time (PT) with normal partial prothrombin time (PTT) may be an indicator for Factor VII deficiency. A family with hereditary heterozygous Factor VII deficiency is presented in whom no symptoms of a bleeding disorder we...

journal_title：Klinische Padiatrie

authors： Laws HJ,Harbrecht U,Köster B

更新日期：1992-11-01 00:00:00

abstract：:Tumors of the central nervous system account for 15.7% of all malignancies registered at the documentation center for childhood malignancies in Western Germany. This group constitutes the largest entity of solid tumors. With the exception of medulloblastoma the five-year survival probability of children with cns tumor...

journal_title：Klinische Padiatrie

authors： Kühl J

更新日期：1987-05-01 00:00:00

abstract：:Radio-labelled antimyosin-monoclonal antibodies (AMA) have been introduced to demonstrate myocardial necrosis after cardiac infarction or in cardiac allograft transplants. As rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS) are tumors of myogenic origin, thus often containing myosin, we decided to use the 111In-labelle...

journal_title：Klinische Padiatrie

authors： Koscielniak E,Reuland P,Schilling F,Feine U,Treuner J

更新日期：1990-07-01 00:00:00

abstract：:Interferons are components of the nonspecific defense system. Their most prominent biological roles are the antiviral, the antiproliferative, and the immunoregulatory activities. However, their primary functions within the organism remains to be determined. Three types of IFNs have been described so far (IFN alpha, IF...

journal_title：Klinische Padiatrie

authors： Jacobsen H,Kirchner H

更新日期：1985-07-01 00:00:00

abstract：:23 children with acute spinal syndromes are presented. The clinical signs were caused by trauma in 11 patients, by extramedullary tumors in 6, by operations (coarctation of the aorta, scoliosis) in 4 and by encephalomyelitis in 2. Motor signs (flaccid paraplegia or paraparesis, monoplegia, bilateral weakness) and chan...

journal_title：Klinische Padiatrie

authors： Bode H,Bubl R,Hefti F,Signer E,Wyler F

更新日期：1993-09-01 00:00:00

abstract：:Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...

journal_title：Klinische Padiatrie

authors： Uhlenbruck G,Scheuring U,Dienst C,Kaiser D,Roth B,Skopnik H

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Lupus vulgaris (LV) is the most common form of cutaneous tuberculosis (TB) in Europe, nevertheless the overall incidence is low. It constitutes about 1.5% of all extra-pulmonary cases worldwide. A slight raise in TB incidence rates among children was recently registered in Germany, which can be explained by ...

journal_title：Klinische Padiatrie

authors： Striegel AK,Nazzal R,Fabri M,Rietschel E,Dötsch J,Mauch C,Tantcheva-Poor I

更新日期：2014-01-01 00:00:00

abstract：:Central nervous system (CNS) tumors account for the highest mortality among pediatric malignancies. Accurate diagnosis is essential for optimal clinical management. The increasing use of molecular diagnostics has opened up novel possibilities for more precise classification of CNS tumors. We here report a single-insti...

journal_title：Klinische Padiatrie

authors： Bächli H,Ecker J,van Tilburg C,Sturm D,Selt F,Sahm F,Koelsche C,Grund K,Sutter C,Pietsch T,Witt H,Herold-Mende C,von Deimling A,Jones D,Pfister S,Witt O,Milde T

更新日期：2018-10-01 00:00:00

abstract：:16 term and preterm neonates received intravenous nutriton for at least three days. The dosage was 1--2 g amino acids, 1 g of fat, and 8--10 g glucose per kg body weight and day. Compatibility was investigated by daily determinations of the amino acid pattern in the serum and measurement of free fatty acids and trigly...

journal_title：Klinische Padiatrie

authors： Petrich C,Stephan U,Remy R,von Voss H,Göbel U,Herpertz LM

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Spinal compression can be a complication of neuroblastoma (NBL). Delayed or insufficient treatment of this condition may lead to permanent neurological sequelae. Therefore, appropriate treatment should be introduced promptly. Therapeutic options include neurosurgery, chemotherapy, and radiation therapy. CAS...

journal_title：Klinische Padiatrie

authors： Walter KN,Kratz C,Uhl M,Niemeyer C

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Burning pain of red and warm hands and/or feet are the classical symptoms of erythromelalgia. CASE REPORT:We describe the symptoms of acute idiopathic erythromelalgia and arterial hypertension in a five-year-old boy. Five days after a gastroenteritis the patient developed burning hands and feet in combinati...

journal_title：Klinische Padiatrie

authors： Zenz W,Zöhrer B,Zobel G,Schulze-Bauer C

更新日期：1999-11-01 00:00:00

abstract：:This is a report of the neonatal form of nonketotic hyperglycinemia with rapid progressing neurological symptoms, respiratory distress and seizures. The EEG pattern is characteristic, the ratio of cerebrospinal fluid to plasma glycine abnormally high. The result of cranial computerized tomography demonstrates also in ...

journal_title：Klinische Padiatrie

authors： Plöchl E,Rittinger O,Doringer E,Laubichler W

更新日期：1991-11-01 00:00:00

abstract：:Scoring systems for evaluation of the degree of severity in patients with cystic fibrosis are critically evaluated. Cross-sectional comparison of Shwachman's score, Cooperman's score, Taussig-NIH score, Bernese score and Huang score reveals that advantages and disadvantages of each score exist. In early days used as a...

journal_title：Klinische Padiatrie

authors： Schöni MH

更新日期：1993-01-01 00:00:00

abstract：:Carcinomas of the plexus choroideus (PCC) represent the rare malignant variety of plexus choroideus papillomas and take a particularly unfavourable course. Tumors of the plexus choroideus account for about 2-4% of all primary brain tumors in children and 0.5% of those in adults. The PCC is more frequent in children th...

journal_title：Klinische Padiatrie

authors： Peschgens T,Stollbrink-Peschgens C,Mertens R,Völker A,Thron A,Heimann G

更新日期：1995-03-01 00:00:00

abstract：:Centralized treatment of critically ill pediatric patients and related problems are presented. Pediatric intensive care allows to overbridge deranged or interrupted organ functions while simultaneously treating the disease causing the disturbance. Its efficiency depends on continuity of medical care. Medical and nursi...

journal_title：Klinische Padiatrie

authors： Wille L

更新日期：1980-09-01 00:00:00