[Therapy-related central nervous system complications in acute lymphoblastic leukemia and non-Hodgkin's lymphoma of childhood (author's transl)].

Abstract:

:An increasing number of children with acute leukemia show cerebral complications. 10 out of 78 children treated in our hospital for acute lymphoblastic leukemia or non-Hodgkin's lymphoma who underwent remission induction therapy or were in continuous complete remission developed central nervous system complications. During intensive initial therapy, intracerebral hemorrhages (2) and metabolic disturbances with concomitant cerebral convulsions (3) were seen. Unusual central-nervous infections occured in each treatment period (3). Cerebral degenerations could be observed only during the maintenance therapy (2). Cerebral convulsions were the leading symptom in 7 children. With intensive control of the coagulation system and the metabolic parameters central nervous system complications in the treatment of acute lymphoblastic leukemia should be reduced significantly.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Ludwig R,Meyer E,Brandeis WE

doi

10.1055/s-2008-1035608

subject

Has Abstract

pub_date

1980-07-01 00:00:00

pages

358-64

issue

4

eissn

0300-8630

issn

1439-3824

journal_volume

192

pub_type

杂志文章
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    更新日期:1996-07-01 00:00:00

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  • [Therapy of choroid plexus carcinoma in childhood. Case report and review of the literature].

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    doi:10.1055/s-2008-1034383

    authors: Klingmüller V

    更新日期:1983-07-01 00:00:00

  • [Supplementary intravenous nutrition in term and preterm neonates (author's transl)].

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    更新日期:1979-07-01 00:00:00

  • [Measles epidemic in a highly developed country: low mortality, high morbidity and extensive costs].

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    更新日期:1990-05-01 00:00:00

  • [Parents and oncology team members are getting together after the death of a child. Report from Children's hospital Tübingen].

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  • [Initial response to therapy as an important prognostic factor in acute lymphoblastic leukemia in childhood. COALL study group].

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    doi:

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    更新日期:1976-05-01 00:00:00

  • [The clinical significance of pseudouridine determination of the urine in children and adolescents].

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    doi:

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