[Treatment of chronic myeloid leukemia in children and adolescents--concept of the multicenter pilot study CML-ped].

abstract：:The GPOH-MAHO trials designed in 3/82 and 7/88 for treatment of childhood testicular germ cell tumors registered 3/92 105 pts. In MAHO 82 study 57 pts. and in MAHO 88 study 48 pts. were treated. Histologically 60% of the tumors revealed yolk sac tumors (YST), 22% teratomas (TD) and 18% malignant teratomas (MTI, MTU, M...

journal_title：Klinische Padiatrie

authors： Haas RJ,Schmidt P,Göbel U,Harms D

更新日期：1993-07-01 00:00:00

abstract：:Hereditary Factor VII deficiency is one of the rare congenital coagulopathies. Prolonged prothrombin time (PT) with normal partial prothrombin time (PTT) may be an indicator for Factor VII deficiency. A family with hereditary heterozygous Factor VII deficiency is presented in whom no symptoms of a bleeding disorder we...

journal_title：Klinische Padiatrie

authors： Laws HJ,Harbrecht U,Köster B

更新日期：1992-11-01 00:00:00

abstract：:The control of severe infectious complications by preventive strategies, early diagnosis of infections and empiric broad-spectrum antibiotic therapy contributed to a marked improvement of survival in children with cancer over the last 20 years. This article overviews of the importance of prevention of infectious compl...

journal_title：Klinische Padiatrie

authors： Fleischhack G,Simon A

更新日期：2001-09-01 00:00:00

abstract：:The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither...

journal_title：Klinische Padiatrie

authors： Schneppenheim R,Rautenberg P,Behnke H,Vietor K

更新日期：1991-07-01 00:00:00

abstract：:The biologic behaviour of teratomas depends on various interdependent clinical and epidemiologic variables such as the age at diagnosis, sex, tumor site, histology which all correlate to different cytogenetic and molecular biologic aberrations. Thus, testicular teratomas of infancy are generally benign. Accordingly, p...

journal_title：Klinische Padiatrie

authors： Harms D,Zahn S,Göbel U,Schneider DT

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:It has been shown that Interleukin 10 (IL-10) is able to inhibit alloreactivity in a mixed lymphocyte culture. Therefore, here IL-10 production in patients after allogeneic BMT was investigated and correlated with the incidence of acute GvHD. PATIENTS:14 patients after allogeneic BMT have been investigated....

journal_title：Klinische Padiatrie

authors： Körholz D,Hempel L,Packeisen J,Kunst D,Zintl F,Burdach S

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Thermal injuries are a frequent cause of accidents within the pediatric population that may result in long periods of hospitalization as well as severe physical and mental impairment and lifelong consequences. Especially in infants, burns caused by scalding are the most common cause of injury. Beside acciden...

journal_title：Klinische Padiatrie

authors： Klinke M,Schmidt CM,Tegtmeyer L,Reinshagen K,Boettcher M,Koenigs I

更新日期：2018-03-01 00:00:00

abstract：:Megestrol acetate (MA) is a synthetic, orally active derivative of the naturally occurring hormone progesterone. MA is increasingly used to correct loss of appetite and improve the nutritional status. We used MA in an adolescent with growth hormone (GH) deficiency due to former irradiation therapy in order to evaluate...

journal_title：Klinische Padiatrie

authors： Schmid I,Stachel DK,Freudenberg S,Schmitt M,Schuster F,Haas RJ

更新日期：2002-03-01 00:00:00

abstract：:Problems of terminology, differential diagnosis, etiology and therapy of language development disorders are demonstrated by a casuistic example. Besides the importance of clinical date special attention was laid on neuropsychological diagnostic procedures and their therapeutic implications. Therapeutic interventions c...

journal_title：Klinische Padiatrie

authors： Niebergall G,Wiesse J

更新日期：1978-09-01 00:00:00

abstract：:Since 1962, desferrioxamine (deferoxamine, DFO) has been utilized for the treatment of secondary hemosiderosis. For about 30 years, DFO therapy has been performed as nightly continuous subcutaneous infusion. About 20 years ago, the first oral iron chelator (deferiprone, DFP) was presented. Concerns about potential sid...

journal_title：Klinische Padiatrie

authors： Cario H,Janka-Schaub G,Janssen G,Jarisch A,Strauss G,Kohne E

更新日期：2007-05-01 00:00:00

abstract：:The long term follow up of 55 children with allergy treated by specific hyposensitization therapy is reported. Hyposensitization therapy had been terminated from 2--7 years previously. The success of treatment was subjectively judged to be satisfactory of good in 62% of the cases. In the group of asthmatic children, a...

journal_title：Klinische Padiatrie

authors： Urbanek R,Karitzky D

更新日期：1975-11-01 00:00:00

abstract：:Hypotension is diagnosed in a high percentage of very low birth weight infants, particularly in the first 24 hours after birth and the resultant clinical approach is to support the blood pressure vigorously. However, the research base is not yet available to give a definite answer to the question, which blood pressure...

journal_title：Klinische Padiatrie

authors： Stopfkuchen H

更新日期：2003-01-01 00:00:00

abstract：:A multi-center retrospective survey was conducted to evaluate the incidence and types of hemostatic complications occurring in children with acute lymphoblastic leukemia (ALL) during treatment according to the ALL-BFM-90 treatment protocol. All of the BFM-treatment centers (n = 77) were approached and a 95% response r...

journal_title：Klinische Padiatrie

authors： Sutor AH,Mall V,Thomas KB

更新日期：1999-07-01 00:00:00

abstract：UNLABELLED:The congenital syphilis is an infectious fetopathy which is able to affect the whole organism. In most cases symptoms are not obvious before week fourth to twelve of life. The infection of the mother is the precondition for the child's disease. The placental transfer takes place after the fifth to sixth mont...

journal_title：Klinische Padiatrie

authors： Vieker S,Siefert S,Lemke J,Püst B

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:First-line treatment in AML commonly included high cumulative doses of anthracyclines with an increasing risk of cardiotoxicity. Liposomal daunorubicin (L-DNR) is thought to be less cardiotoxic without impairment of efficacy. METHODS:The AML-BFM REZ 97 study included two reinduction blocks with L-DNR (2 x 6...

journal_title：Klinische Padiatrie

authors： Reinhardt D,Hempel G,Fleischhack G,Schulz A,Boos J,Creutzig U

更新日期：2002-07-01 00:00:00

abstract：:Newly diagnosed immune thrombocytopenia occurs in 3-5/100 000 children < 14 y per year. Bleeding symptoms do not correlate with platelet count. Diagnostic approach includes history, clinical examination and analysis of blood count with blood smear by experienced hematologist. Additional investigations are only necessa...

journal_title：Klinische Padiatrie

authors： Eberl W,Dickerhoff R,Pediatric Committee of Society of Thrombosis and Hemostasis Research.

更新日期：2012-04-01 00:00:00

abstract：:630 neonates with risk factors of perinatal hearing impairment were screened of hearing loss by means of registration of transient otoacoustic emissions before discharge from the newborn nursery. Neonates were screened additionally by means of brainstem evoked response audiometry, if they had bilateral negative emissi...

journal_title：Klinische Padiatrie

authors： Sitka U,Rehm K,Rasinski C

更新日期：1998-03-01 00:00:00

abstract：:16 term and preterm neonates received intravenous nutriton for at least three days. The dosage was 1--2 g amino acids, 1 g of fat, and 8--10 g glucose per kg body weight and day. Compatibility was investigated by daily determinations of the amino acid pattern in the serum and measurement of free fatty acids and trigly...

journal_title：Klinische Padiatrie

authors： Petrich C,Stephan U,Remy R,von Voss H,Göbel U,Herpertz LM

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Supraventricular reentrant tachycardias are the most common cardiac arrhythmia observed in infancy and childhood. The often benign clinical course of the disease warrants careful selection of any antiarrhythmic drug given to prevent recurrencies, in order to avoid potentially dangerous side-effects such as p...

journal_title：Klinische Padiatrie

authors： Pfammatter JP,Weber JW,Stocker FP

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Surveys in USA and UK have shown inconsistencies between practice of sweat testing and guidelines of the National Committee for Clinical Laboratory Standards (NCCLS), which could increase the risk of false-positive and -negative results. To determine the current practice of sweat testing in German cystic fib...

journal_title：Klinische Padiatrie

authors： Naehrlich L

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:In the German guidelines for prophylaxis of group B streptococcal (GBS) early onset sepsis in neonates (EOS), GBS screening of all pregnant women has been recommended, but is not yet included in the Maternity Directives. Aim of the study was to identify temporal trends in incidence of EOS and their associati...

journal_title：Klinische Padiatrie

authors： Sorg AL,Obermeier V,Armann J,Klemme M,von Kries R

更新日期：2021-01-01 00:00:00

abstract：:Low birth weight babies and sick full-term babies, who require total parenteral nutrition and repeated intravenous applications of drugs, which irritate peripheral veins, very often need a reliable central venous catheter. The aim of our paper was to study prospectively the efficiency and the complications of peripher...

journal_title：Klinische Padiatrie

authors： Sterniste W,Vavrik K,Lischka A,Sacher M

更新日期：1994-01-01 00:00:00

abstract：AIM:Reports describing coronavirus disease 2019 (Covid-19) in children are fewer than adult studies due to milder clinical picture. We aimed to share our experience at a single center with an emphasis on collective decision making. MATERIALS AND METHODS:A suspected case was defined as the presence of symptoms suggesti...

journal_title：Klinische Padiatrie

authors： Duramaz BB,Turel O,Korkmaz C,Karadogan MT,Yozgat CY,Iscan A,Sümbül B,Erenberk U

更新日期：2021-01-01 00:00:00

abstract：:Reliability and accuracy of the measured ventilatory and lung mechanical parameters of different diagnostic systems (SensorMedics 2600, Med-Science RDS 4500) and respiratory monitoring systems (BI-CORE CP-100, monitor of Babylog 8000) were investigated using a mechanical lung model. The accuracy of pressure and volume...

journal_title：Klinische Padiatrie

authors： Hauschild M,Schmalisch G,Wauer RR

更新日期：1994-05-01 00:00:00

abstract：:An increasing number of children with acute leukemia show cerebral complications. 10 out of 78 children treated in our hospital for acute lymphoblastic leukemia or non-Hodgkin's lymphoma who underwent remission induction therapy or were in continuous complete remission developed central nervous system complications. D...

journal_title：Klinische Padiatrie

authors： Ludwig R,Meyer E,Brandeis WE

更新日期：1980-07-01 00:00:00

abstract：:Radionuclide lumbar cisternography with 111In-DTPA was utilized as a bedside procedure to evaluate CSF dynamics and the patency of the ventricular system in 29 preterm infants with hydrocephalus. Serial images of the brain were obtained at 0, 1, 2, 6, 24 and 48 hours after instillation of the isotope in the lumbar sub...

journal_title：Klinische Padiatrie

authors： Roloff DW

更新日期：1985-03-01 00:00:00

abstract：:A HPLC-method is described to determine the Pseudouridine/creatinine ratio in spontaneous urine samples in infancy and childhood. The urines of 74 healthy children between 1 and 18 years of age and of 231 children with different diseases were examined for this ratio, making 1097 measurements. 157 children suffered fro...

journal_title：Klinische Padiatrie

authors： Graf N,Bach K,Frisch B,Haas HJ,Sitzmann FC

更新日期：1989-05-01 00:00:00

abstract：:Inherited disorders of platelets constitute a group of rare diseases that give rise to bleeding syndromes of variety severity, with more severe cases being first diagnosed during infancy and childhood. To appropriate diagnose a platelet function disorder during early childhood the knowledge of the physiological charac...

journal_title：Klinische Padiatrie

authors： Schlegel N,Bardet V,Kenet G,Muntean W,Zieger B,Nowak-Göttl U,Working Group on Standardisation in Perinatal and Pediatric Hemostasis.

更新日期：2010-05-01 00:00:00

abstract：:Bacteriologic cultures of the vagina and the cervix of 38 praepubertal children, aged 3 months to 16 years (average age 9 years) from the outpatient department for infants and juveniles of the 1st Department of Obstetrics and Gynecology of the University of Vienna were obtained vaginascopically using anaerobic transpo...

journal_title：Klinische Padiatrie

authors： Gerstner G,Boschitsch E,Grünberger W,Rotter M

更新日期：1982-01-01 00:00:00

abstract：:The observation of constitutional chromosome abnormalities in a one and half year old boy with Wiedemann-Beckwith syndrome (WBS) and hepatoblastoma prompted us to review the currently available literature dealing with this subject. In approximately 500 published cases with complete and incomplete forms of WBS, 42 mali...

journal_title：Klinische Padiatrie

authors： Haas OA,Zoubek A,Grümayer ER,Ferstl G,Gadner H

更新日期：1987-07-01 00:00:00