[Importance of prevention of infectious complications in pediatric hematologic-oncologic patients].

abstract：BACKGROUND:Intrauterine growth restriction seems to be a risk factor for an aggravated course of secondary renal diseases in children. Catch-up growth after birth may play a critical role. We tested if there is an association between an aggravated course of nephritis in Henoch-Schönlein Purpura (PSHN) and low birth wei...

journal_title：Klinische Padiatrie

authors： Plank C,Vasilache I,Dittrich K,Dötsch J

更新日期：2010-12-01 00:00:00

abstract：:In the period from 1965 to 1979 biopsies from the oropharynx of 11 children with non-Hodgkin's lymphoma were collected at the Lymph Node Registry in Kiel. Palatine tonsil tissue was examined in all cases and, in addition, specimens from the retrolingual region of one child and the epipharynx of two patients. All biops...

journal_title：Klinische Padiatrie

authors： Schwarze EW,Mrowietz B,van Ackeren G

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Flank swelling and pseudotumors of the kidney are unusual manifestations of obstructive uropathies in small children. Our case illustrates typical problems and briefly reviews management options. CASE REPORT:A 5-week-old boy presented with a large, palpable urinoma due to posterior urethral valves. Sonograp...

journal_title：Klinische Padiatrie

authors： von Schnakenburg C,Dorn A,Jacobi C,Fisch D,Pohl M,Frankenschmidt A

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Alcoholism during pregnancy is one of the most common factors in western societies causing persisting congenital and multiple physical as well as neurological impairments. Finding the diagnosis at first sight puts medical professionals into a demanding situation. Therefore the objective of this study was to ...

journal_title：Klinische Padiatrie

authors： Alex K,Feldmann R

更新日期：2012-03-01 00:00:00

abstract：:This is a case-report about a 4 year old boy with "cherry red" epiglottis, purulent meningitis and pleuropneumonia. Purulent meningitis and pleuropneumonia are not complications of treatment of "cherry red" epiglottis but an entity caused by Hemophilus influenzae-infection and is called Kleinschmidt's syndrome (Hemoph...

journal_title：Klinische Padiatrie

authors： Freudenberg V,Wolf H

更新日期：1976-07-01 00:00:00

abstract：:Scoring systems for evaluation of the degree of severity in patients with cystic fibrosis are critically evaluated. Cross-sectional comparison of Shwachman's score, Cooperman's score, Taussig-NIH score, Bernese score and Huang score reveals that advantages and disadvantages of each score exist. In early days used as a...

journal_title：Klinische Padiatrie

authors： Schöni MH

更新日期：1993-01-01 00:00:00

abstract：:We have performed in situ hybridization (ISH) studies predominantly on paraffin sections and on isolated nuclei of 22 pediatric germ cell tumors (GCTs) from 18 patients including 4 recurrences from three patients. In addition, we performed conventional cytogenetic analyses in three tumor samples. Because reports on cy...

journal_title：Klinische Padiatrie

authors： Stock C,Ambros IM,Strehl S,Zoubek A,Fink FM,Gadner H,Ambros PF

更新日期：1995-07-01 00:00:00

abstract：:An unbalanced structural chromosome aberration was found in a 6-year-old girl. Mother and maternal grandmother were shown to be carriers of a complex balanced translocation involving chromosomes 1, 5 and 15 and are of normal phenotype. The unbalanced status in the proband was defined as a partial trisomy 1p21-1p31. Pa...

journal_title：Klinische Padiatrie

authors： Schürmann M,Wethling H,Niemeyer ML,Schwinger E

更新日期：1987-01-01 00:00:00

abstract：:The lipodystrophy syndromes are rare disorders characterized by the loss of adipose tissue. The loss of fat tissue can have genetic, immune, or infectious/drug-associated causes. With the extent of fat loss metabolic complications, such as insulin resistance, diabetes mellitus, hypertriglyceridemia, and fatty liver in...

journal_title：Klinische Padiatrie

authors： Fischer-Posovszky P,Debatin KM,Wabitsch M

更新日期：2002-05-01 00:00:00

abstract：:Aim of the present study was to test whether six-hour (6 h) urine specimens predict the 24-hour (24 h) mineral homeostasis in individual infants born preterm. Urinary Calcium (Ca) and Phosphate (P) concentrations were studied in 60 stable infants; gestational age 34 (25-42) weeks. In 58 infants four 6 h urine specimen...

journal_title：Klinische Padiatrie

authors： Mihatsch W,Trotter A,Pohlandt F

更新日期：2012-03-01 00:00:00

abstract：:The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither...

journal_title：Klinische Padiatrie

authors： Schneppenheim R,Rautenberg P,Behnke H,Vietor K

更新日期：1991-07-01 00:00:00

abstract：:Case report of arthrogryposis multiplex congenita with histologically proved neutrogene atrophy of muscles. The also existing reduction deformities of the limbs, showing aplasia and hypoplasia of phalanges may hypothetically be of neuropathic origin. ...

journal_title：Klinische Padiatrie

authors： Eckel U,Spranger J,Klein H

更新日期：1979-05-01 00:00:00

abstract：:During the last 6 years 73 previously untreated children and adolescents with acute lymphoblastic leukemia were enrolled on a non-randomized therapy protocol. In this longitudinal study the specific accent was put on the intensified induction treatment of 8 weeks' duration which was thought to achieve a higher remissi...

journal_title：Klinische Padiatrie

authors： Riehm H,Gadner H,Welte K

更新日期：2013-05-01 00:00:00

abstract：:A case of true hermaphroditism was described. The patient had an uterus, a fallopian tube, a testide on the left in the position of the ovary and an ovary on the right side. The chromosome picture corresponded to a 47, XXY/46, XX/46 XXY mosaic. The phenotype of the patient was male so the decision for male sex seemed ...

journal_title：Klinische Padiatrie

authors： Barta L,Konyar E,Regöly-Merei A,Toth J

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND:Surveys in USA and UK have shown inconsistencies between practice of sweat testing and guidelines of the National Committee for Clinical Laboratory Standards (NCCLS), which could increase the risk of false-positive and -negative results. To determine the current practice of sweat testing in German cystic fib...

journal_title：Klinische Padiatrie

authors： Naehrlich L

更新日期：2007-03-01 00:00:00

abstract：:An eight-year old girl showing a X/X-translocation (45,X/46,Xt(X;X)(q26;p11)) is presented. Besides short stature and congenital heart-anomaly no other phenotypical abnormalities were present. In all cells containing the abnormal X-chromosome, the latter was late labeling as shown by autoradiography and BrdU-labeling....

journal_title：Klinische Padiatrie

authors： Wagenbichler P,Frisch H,Schnedl W

更新日期：1975-11-01 00:00:00

abstract：:Autoimmune hemolytic anaemia (AIHA) in childhood is associated with antibodies produced by the patient himself, which coat his red cells causing their hemolysis. Although in some cases no underlying disease could be found, in the majority of children a virus etiology is apparent. There are very few reports regarding t...

journal_title：Klinische Padiatrie

authors： Haas RJ,Pöschl U,Christ M,Schaub J,Belohradsky BH

更新日期：1977-05-01 00:00:00

abstract：:Transfusion-induced hemochromatosis remains a major therapeutic complication in the management of patients with chronic hemolytic anemias. Red cell units harvested with blood cell separators have an average estimated mean cell age of 30 days, compared to 60 days for unfractionated blood. Our initial experience with tr...

journal_title：Klinische Padiatrie

authors： Heim MU,Eckstein R,Mittermüller H,Haas RJ,Schmidt P,Graebner E,Pape W,Mempel W

更新日期：1985-03-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of infancy and young childhood. The clinical presentation includes recurrent unexplained fever with hepatosplenomegaly. Cytopenia, hypofibrinogenemia and/or hypertriglyceridemia and hemophagocytosis in bone marrow, spleen and lymphnode confirm the diagnosis. H...

journal_title：Klinische Padiatrie

authors： Dürken M,Schneider EM,Blütters-Sawatzki R,Stollmann-Gibbels B,Nessler G,Bretz R,Körholz D,Probst EN,Holsten-Griffin H,Harps E,Zander AR,Janka GE

更新日期：1998-07-01 00:00:00

abstract：HINTERGRUND: Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. ZIELSETZUNG: Ziel dieser Studie ist es, mögliche Sym...

journal_title：Klinische Padiatrie

authors： Gerstl L,Weinberger R,von Kries R,Heinen F,Sebastian Schroeder A,Veronika Bonfert M,Borggräfe I,Tacke M,Vill K,N Landgraf M,Kurnik K,Olivieri M

更新日期：2018-10-01 00:00:00

abstract：:We report about two patients with compression of the spinal cord caused by lymphosarcomas. In the first patient the tumour was localized in the lumbal region and destroyed two vertebrae. In the second patient the lymphosarcoma also infiltrated the meninx, the cord, and some internal organs. Both children died. ...

journal_title：Klinische Padiatrie

authors： Kaufmann U

更新日期：1979-03-01 00:00:00

abstract：:Hepatotoxicity of valproic acid (VPA) is reported in a psychomotor retarded boy. A four-month antiepileptic therapy was followed by a combined VPA/phenytoin treatment where-upon, two months later, the patient died in a hepatic coma. In the final state the metabolic pattern of VPA was still found within the normal rang...

journal_title：Klinische Padiatrie

authors： Keulen FP,Kochen W

更新日期：1985-09-01 00:00:00

abstract：:In a randomised study the efficacy of a cytomegalic hyperimmune globulin preparation (CMV-HIGP) which had been treated with beta-propiolactone was analysed. The study included 85 patients with acute lymphoblastic leukemia (ALL) and Non-B-Non-Hodgkin-lymphoma (NHL) who were treated initially or underwent a relapse ther...

journal_title：Klinische Padiatrie

authors： Gerein V,Kropp H,Schwabe D,Gussetis E,Langer B,Kornhuber B

更新日期：1989-07-01 00:00:00

abstract：:A case of an infant with a mediastinal neurenteric cyst is used to review this rare entity. By definition a neurenteric cyst is the combination of an entodermal cyst with a vertebral dysplasia. Neurenteric cysts are located in the posterior mediastinum, preferentially on the right side. In a third of the patients thes...

journal_title：Klinische Padiatrie

authors： Köster B,Emons D,Kunath U,Födisch HJ

更新日期：1987-01-01 00:00:00

abstract：:Immunocompromised patients in pediatric hematology-oncology are faced with an increased risk of nosocomial infections (NI). The incidence of NI and the contribution of certain risk factors have not sufficiently been investigated in this population. It is therefore unknown how many NI are preventable through infection ...

journal_title：Klinische Padiatrie

authors： Simon A,Fleischhack G

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Congenital Central Hypoventilation Syndrome (CCHS, Ondine's curse) is a rare syndrome of dysfunction of the autonomic nervous system characterized by a decreased response to hypercarbia requiring mechanical ventilation in most cases. CCHS is an autosomal-dominant disease associated with tumors of neural cres...

journal_title：Klinische Padiatrie

authors： Hammel M,Klein M,Trips T,Priessmann H,Ankermann T,Holzinger A

更新日期：2009-09-01 00:00:00

abstract：:In a retrospective study we evaluated clinical features and diagnostic impact of sonography, white blood cell count, C-reactive protein as well as bacterial etiology of children treated surgically for bacterial cervical lymphadenitis. We report on 38 children at the age between 2.5 months and 14 years who were admitte...

journal_title：Klinische Padiatrie

authors： Tröbs RB,Gräfe G,Müller P,Handrick W

更新日期：2003-07-01 00:00:00

abstract：:This is a report of the neonatal form of nonketotic hyperglycinemia with rapid progressing neurological symptoms, respiratory distress and seizures. The EEG pattern is characteristic, the ratio of cerebrospinal fluid to plasma glycine abnormally high. The result of cranial computerized tomography demonstrates also in ...

journal_title：Klinische Padiatrie

authors： Plöchl E,Rittinger O,Doringer E,Laubichler W

更新日期：1991-11-01 00:00:00

abstract：:Neurofibromatosis type 1 is the most common of the phakomatoses and the clinical follow-up is an interdisciplinary challenge. The data of 27 patients with NF1 were systematically reviewed and compared to data from the literature. All of our patients had clinical signs of NF1. Besides the classic criteria café-au-lait ...

journal_title：Klinische Padiatrie

authors： Syrbe S,Eberle K,Strenge S,Bernhard MK,Herbertz S,Bierbach U,Hirsch W,Froster UG,Kiess W,Merkenschlager A

更新日期：2007-11-01 00:00:00

abstract：:Positive anti-DNA-antibodies and lowered C3 and C4 levels were found in serum of a 13 year old girl presenting with edema, microscopic hematuria and proteinuria. Renal biopsy revealed diffuse endo- and extracapillary glomerulonephritis with mesangial deposits of IgA, IgG, IgM, C1q, C3 and fibrinogen. In spite of treat...

journal_title：Klinische Padiatrie

authors： Michalk D,Scharf J,Waldherr R

更新日期：1983-11-01 00:00:00