[Hepatotoxicity of valproic acid treatment].

abstract：:Severe combined immunodeficiency (SCID) is a heterogeneous group of congenital diseases characterized by their presentation with life threatening infections in the first months of life. The clinical presentation and the therapeutic outcome is influenced by multiple factors: the genetic defect, infectious complications...

journal_title：Klinische Padiatrie

authors： Hönig M,Schulz A,Friedrich W

更新日期：2011-11-01 00:00:00

abstract：:Since 1987, the authors have examined 186 patients (76 girls, 110 boys) with a variety of congenital and acquired heart diseases by means of magnetic resonance imaging (MRI). The patients' ages ranged from 2 days to 20 years (mean age 3.97 years). During the study new techniques were developed, which extend the applic...

journal_title：Klinische Padiatrie

authors： Sieverding L,Jung WI,Fleiter TH,Klose U,Steil E,Hassberg D,Rosendahl W

更新日期：1992-09-01 00:00:00

abstract：:Report about cyclic agranulocytosis in a 10 1/2 years old girls, having stomatitis, sore throat and fever up to 39 degrees C in the interval of approximately 3 weeks since the age of 6 months. By the prophylactic treatment with pulverized tetracyclin, which is already given 2 days prior to the expected decrease of the...

journal_title：Klinische Padiatrie

authors： Schönberger W,Schönberger G,Stopfkuchen H

更新日期：1975-03-01 00:00:00

abstract：:16 patients of studies AML-BFM-83 and -87 with allogeneic bone marrow transplantation (BMT) in first complete remission (CR) were compared with matched controls with postremission chemotherapy (CT-MC). CT-MC were selected from 250 non-grafted patients with a minimum of remission duration corresponding to the median in...

journal_title：Klinische Padiatrie

authors： Creutzig U,Bender-Götze C,Klingebiel T,Ebell W,Friedrich W,Stollmann-Gibbels B,Schmidt H,Suttorp M,Gratwohl A,Heyen P

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Autism spectrum disorders (ASDs) are a group of developmental disabilities in childhood and adolescence. Beside genetic predisposition also environmental influences may contribute to the ASD pathogenesis. Family members of children and adolescents with ASD often ask for specific diets to alleviate ASD-associ...

journal_title：Klinische Padiatrie

authors： Sausmikat J,Smollich M

更新日期：2016-03-01 00:00:00

abstract：:The case of a newborn with duplications of rectum, presenting as a tumor of the labia majora, and duplication of bladder and urethra is reported. In addition malformations from the VACTERL-association (sacral malformation, anal atresia with vestibulum fistula, renal dysplasia, only eleven pairs of ribs with hypoplasia...

journal_title：Klinische Padiatrie

authors： Santer R,Schröder H

更新日期：1987-03-01 00:00:00

abstract：:Infectious complications are a major cause of morbidity and mortality in pediatric and adult patients undergoing hematopoietic stem cell transplantation. The incidence and the severity code of infections depend on the function of the host's immune system. This function is strongly correlated to the application of immu...

journal_title：Klinische Padiatrie

authors： Schuster FR,Laws HJ

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Current resuscitation guidelines recommend the use of simulation-based medical education (SBME) as an instructional methodology to improve patient safety and health. We sought to investigate the evidence-base for the effectiveness of SBME for neonatal and pediatric resuscitation training. METHOD:Therefore, ...

journal_title：Klinische Padiatrie

authors： Mileder LP,Urlesberger B,Szyld EG,Roehr CC,Schmölzer GM

更新日期：2014-09-01 00:00:00

abstract：:The phagocytic and NBT reduction indices of 94 preterm and underweight babies, divided into 7 groups and two weight classes, were observed over a period of six weeks while they were observed over a period of six weeks while they were given four commercial baby foods (Humana 0, Meb, Multival, Pomil). In all groups the ...

journal_title：Klinische Padiatrie

authors： Jeschke R,Ströder J

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...

journal_title：Klinische Padiatrie

authors： Waitz M,Nusser S,Schmid MB,Dreyhaupt J,Reister F,Hummler H

更新日期：2016-09-01 00:00:00

abstract：:In view of present-day knowledge and findings relating to the development of young children, the stimulating interaction between the child and its social and material surroundings must be considered of supreme importance. Any disturbance or radical restriction of the structure of social relationships can thus seriousl...

journal_title：Klinische Padiatrie

authors： Jungmann J

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:The role for testis-sparing surgery in the treatment of primary intratesticular lesions in childhood is growing. The reliability of scrotal ultrasonograpy (US) in the management of these lesions is still controversial. PATIENTS:Between 1991 and 2007, 383 children and adolescents presented with testicular ab...

journal_title：Klinische Padiatrie

authors： Tallen G,Hernáiz Driever P,Degenhardt P,Henze G,Riebel T

更新日期：2011-05-01 00:00:00

abstract：:The lipodystrophy syndromes are rare disorders characterized by the loss of adipose tissue. The loss of fat tissue can have genetic, immune, or infectious/drug-associated causes. With the extent of fat loss metabolic complications, such as insulin resistance, diabetes mellitus, hypertriglyceridemia, and fatty liver in...

journal_title：Klinische Padiatrie

authors： Fischer-Posovszky P,Debatin KM,Wabitsch M

更新日期：2002-05-01 00:00:00

abstract：:In case of painful scoliosis, a search for etiologic factors in the vertebral spinal canal and adjacent structures should be made. MRI with Gadolinium is useful to look for various pathology in and around the spine in particular of spinal cord. CT scanning is indispensible for bony details. Thus CT and MRI are complem...

journal_title：Klinische Padiatrie

authors： Hoeffel C,Gaucher H,Hoeffel JC,Galloy MA,Arnould V

更新日期：1997-03-01 00:00:00

abstract：:The secretory IgA system is common to all mucosal membranes and is presumably of great importance for their defense. In addition to the secretory IgA antibodies produced in a mucosa in response to a local antigenic stimulus there is a spread of this type of IgA response via committed lymphocytes. They originate from c...

journal_title：Klinische Padiatrie

authors： Hanson LA,Andersson B,Carlsson B,Dahlgren U,Mellander L,Porras O,Svanborg Edén C,Söderström T

更新日期：1985-07-01 00:00:00

abstract：:Postoperative neurosonography was performed in 69 babies and children after osteoclastic neurosurgery for primary cerebral tumors. Astrocytoma of the posterior fossa (26 cases) and medulloblastoma (25 cases) were frequent histological findings. Early postoperative bed-side examinations revealed reliably complications ...

journal_title：Klinische Padiatrie

authors： Dittrich M,Gutjahr P,Dinkel E,Higer HP,Müller W

更新日期：1987-11-01 00:00:00

abstract：:This case report describes the forensic examination of 7 girls aged between 4-11 years with suspected sexual abuse. The children had been reported by local pediatricians, hospital physicians or authorities such as the youth welfare office and police due to mucosal changes in the anogenital area. All children presented...

journal_title：Klinische Padiatrie

authors： Navarro-Crummenauer B,Pickhardt CP,Urban R

更新日期：2015-07-01 00:00:00

abstract：UNLABELLED:In the prophylaxis of stress ulcers with antacids in young infants there are no recommendations of dosages that consider the physiologic maturation of gastric acid secretion. During the first six month of life the amount of gastric acid secretion in relation to body weight and body surface area increases exp...

journal_title：Klinische Padiatrie

authors： Kentrup H,Skopnik H,Wolter L,Engelhart W,Nauert C,Heimann G

更新日期：1996-01-01 00:00:00

abstract：:"Lack of space" in utero is considered to be a major factor in the aetiology of the congenital dislocation of the hip. This study tries to answer the question whether hypertrophy of a newborn has to be regarded as a risk factor on the basis of the principle mentioned above. The results of postnatal clinical and sonogr...

journal_title：Klinische Padiatrie

authors： Peschgens T,Skopnik H,Casser HR,Rauschning-Sikora K,Heimann G

更新日期：1993-11-01 00:00:00

abstract：:Possibilities of recognizing cerebral function disturbances in newborns as early as the acute phase of the condition, and of prognosticating permanent brain damage are described. Clinical findings such as lethargy or spasms in the second and third weeks of life following hypoxia indicate severe function disturbances w...

journal_title：Klinische Padiatrie

authors： Karch D

更新日期：1984-11-01 00:00:00

abstract：:The aetiology and pathogenesis of the Duchenne-type muscular dystrophy (pseudohypertrophic muscular dystrophy) are still largely unknown. The possibilities of treating the disease are rather limited. Treatment is the more successful, the earlier diagnosis was possible, and the earlier treatment is initiated. The CK-Sc...

journal_title：Klinische Padiatrie

authors： Beckmann R

更新日期：1978-11-01 00:00:00

abstract：:Hereditary Factor VII deficiency is one of the rare congenital coagulopathies. Prolonged prothrombin time (PT) with normal partial prothrombin time (PTT) may be an indicator for Factor VII deficiency. A family with hereditary heterozygous Factor VII deficiency is presented in whom no symptoms of a bleeding disorder we...

journal_title：Klinische Padiatrie

authors： Laws HJ,Harbrecht U,Köster B

更新日期：1992-11-01 00:00:00

abstract：HINTERGRUND: Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. ZIELSETZUNG: Ziel dieser Studie ist es, mögliche Sym...

journal_title：Klinische Padiatrie

authors： Gerstl L,Weinberger R,von Kries R,Heinen F,Sebastian Schroeder A,Veronika Bonfert M,Borggräfe I,Tacke M,Vill K,N Landgraf M,Kurnik K,Olivieri M

更新日期：2018-10-01 00:00:00

abstract：:From 1968--1978 a longitudinal study was performed concerning development of thorax, upper arm, thigh and calf circumferences in 709 boys and 711 girls 2--15 years old. In boys the mean increase in thoracic circumference amounted to 32.9 cm, in upper are circumference to 8.3 cm, in thigh circumference to 20.6 cm and i...

journal_title：Klinische Padiatrie

authors： Reinken L,Stolley H,Droese W,van Oost G

更新日期：1980-01-01 00:00:00

abstract：:Immunological responses are divided into those mediated by humoral antibody (B-Cells) and those by cells (T-Cells). Both depend upon the activity of small lymphocytes which become thymus or bursa analogue dependent during embryonic development. Primary immundeficiencies are therefor defects of lymphocytes attributed i...

journal_title：Klinische Padiatrie

authors： Haas RJ,Niethammer D,Dietrich M,Kleihauer E

更新日期：1975-11-01 00:00:00

abstract：BACKGROUND:Essential Thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by excessive production of platelets. The disorder is usually affecting adults and is rarely diagnosed in children. PATIENTS AND METHODS:In this retrospective study we describe 12 children aged 5-16 years in whom E...

journal_title：Klinische Padiatrie

authors： Kratz CP,Abd El-Monheim A,Manke EM,Rister M,Rogge T,Niemeyer CM

更新日期：2004-11-01 00:00:00

abstract：:On our opinion one important indication for sonographic diagnosis in future are masses in the larynx area: in infancy or childhood mainly laryngeal papillomatosis. In one of our boy patients with massive laryngeal papillomatosis laser surgery was first performed at 15 months of age. After a second and third procedure ...

journal_title：Klinische Padiatrie

authors： Grunert D,Schöning M,Stier B,Klingebiel T

更新日期：1989-05-01 00:00:00

abstract：:The synchronous occurrence of blasts of the lymphatic and myelogenous lineage in acute leukemia has been rarely observed. Reviewing individual case reports it is suggested that malignant transformation already starts at the level of the stem cell. We are reporting a case of a 13-year old boy who initially showed morph...

journal_title：Klinische Padiatrie

authors： Creutzig U,Eschenbach C,Ritter J,Schellong G

更新日期：1981-05-01 00:00:00

abstract：:Guillain Barré syndrome (GBS; Synonyma: Polyneuritis, Polyradikulitis) is an acute, inflammatory, demyelinating disease of the peripheral nerve system. Clinical hallmarks are symmetric muscle paralysis, areflexia and pronounced autonomic disturbances. Respiratory failure and cardiovascular instability are the main rea...

journal_title：Klinische Padiatrie

authors： Erler T,Weidner B,Wetzel U,Grunske A

更新日期：2008-03-01 00:00:00

abstract：:Oxygen saturation was determined non-invasively with the oxygenmet pulse wave oximeter 1471 and at the same time with the invasive reflectometric method. The determinations were carried out on 49 children (males = 24, females = 25) during 52 catherizations of the heart. Among these children aged between one week and 1...

journal_title：Klinische Padiatrie

authors： Krenkel R,Liappis N,Redel D,Hildenbrand G

更新日期：1981-07-01 00:00:00