[Comparison of chemotherapy alone with allogeneic bone marrow transplantation in first full remission in children with acute myeloid leukemia in the AML-BFM-83 and AML-BFM-87 studies--matched pair analysis].

abstract：:The increasing importance of radiotherapy in tumor of childhood demands the investigation and consideration of the psychological aspects of this afflicting therapy. In this paper the results obtained by questioning and observing 28 children of different ages, their parents, attendants and employees of several radiolog...

journal_title：Klinische Padiatrie

authors： Poehler A,Riedesser P,Jobke A,Wannenmacher M

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Children suffering from life limiting diseases are frequently cared for by adult palliative care teams due to missing paediatric structures in that field. However it is questionable whether palliative care curricula for physicians comprehensively cover issues of paediatric palliative care (PaedPC). AIM:To i...

journal_title：Klinische Padiatrie

authors： Schiessl C,Gottschling S,Gronwald BM

更新日期：2016-01-01 00:00:00

abstract：:Short presentation of the common procedures to avoid transmission of human-immunodeficiency-virus (HIV) by hemoderivates especially clotting-factor-preparations. The stepwise seroconversion (ELISA, IFT, Western-blot) of HIV is shown in a 7 5/12 ys old boy with hemophilia A after administration of a dry-heated factor V...

journal_title：Klinische Padiatrie

authors： Weisser J

更新日期：1988-09-01 00:00:00

abstract：:Background For the new cystic fibrosis (CF) newborn screening program in Germany the Federal Joint Committee (G-BA) implemented a new screening protocol using immunoreactive trypsinogen (IRT) as first and pancreatitis associated protein (PAP) as second tier. Gene analysis with a panel of 31 CFTR-mutations is used as t...

journal_title：Klinische Padiatrie

authors： Sommerburg O,Stahl M,Hammermann J,Okun JG,Kulozik A,Hoffmann G,Mall M

更新日期：2017-03-01 00:00:00

abstract：:Scoring systems for evaluation of the degree of severity in patients with cystic fibrosis are critically evaluated. Cross-sectional comparison of Shwachman's score, Cooperman's score, Taussig-NIH score, Bernese score and Huang score reveals that advantages and disadvantages of each score exist. In early days used as a...

journal_title：Klinische Padiatrie

authors： Schöni MH

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:In the German guidelines for prophylaxis of group B streptococcal (GBS) early onset sepsis in neonates (EOS), GBS screening of all pregnant women has been recommended, but is not yet included in the Maternity Directives. Aim of the study was to identify temporal trends in incidence of EOS and their associati...

journal_title：Klinische Padiatrie

authors： Sorg AL,Obermeier V,Armann J,Klemme M,von Kries R

更新日期：2021-01-01 00:00:00

abstract：:Report on a case of acute childhood leukemia, who presents with the following exceptional features: During complete remission early bilateral leukemic infiltrations of the testes, followed--after an intervall of several months--by a serve, general relapse with ascites. New induction therapy resulted in a second comple...

journal_title：Klinische Padiatrie

authors： Hansen HG,Graucob E

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Disproportionate short stature may impair the quality of life (QoL) of patients and their families. This study aimed to evaluate a self-help supported counseling concept to increase the QoL of the participants. METHODS:QoL data from 58 children/adolescents (8-17 years) with a diagnosis of achondroplasia was...

journal_title：Klinische Padiatrie

authors： Rohenkohl AC,Sommer R,Kahrs S,Bullinger M,Klingebiel KH,Quitmann JH

更新日期：2016-01-01 00:00:00

abstract：:A boy aged 15 years is described in whom a combined autoimmune neutro- and thrombocytopenia developed since the age of 11. Cell-membrane bound IgG antibodies were detected on neutrophils and platelets. A therapy with prednisone and/or immunoglobulins showed only a transient normalization of the peripheral blood values...

journal_title：Klinische Padiatrie

authors： Schneider H,Jobke A,Böhm N

更新日期：1988-01-01 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) is the most common neurocutaneous disease. The clinical manifestations are diverse. Some of the skeletal changes are most relevant to the patient. We report on 9 patients with NF1 who presented with typical pseudarthrosis. In 8 of these children the lower extremity was involved. In 2 cas...

journal_title：Klinische Padiatrie

authors： Ramelli GP,Slongo T,Weis J,Tschäppler H,Vassella F

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...

journal_title：Klinische Padiatrie

authors： Waitz M,Nusser S,Schmid MB,Dreyhaupt J,Reister F,Hummler H

更新日期：2016-09-01 00:00:00

abstract：:Immune neutropenia in infancy comprises alloimmune neutropenia and autoimmune neutropenia. Both diseases are caused by granulocyte-specific antibodies. Patients are newborns and children, often being younger than three years. Neutropenia usually leads to recurrent mild bacterial infections. Beside the blood count and ...

journal_title：Klinische Padiatrie

authors： Bux J,Mueller-Eckhardt C

更新日期：1989-11-01 00:00:00

abstract：:With the advent of prenatal diagnosis and the feasibility of intrauterine treatment, non-immune hydrops fetalis (NHIF) is gaining increasing importance. 14 patients are reported 10 of whom having been diagnosed prenatally. 13 were born prematurely severe asphyxia being a frequent occurrence. 7 out of 14 infants surviv...

journal_title：Klinische Padiatrie

authors： Kühl PG,Ulmer HE,Schmidt W,Wille L

更新日期：1985-07-01 00:00:00

abstract：:Review of a rare multisystem disorder with the main symptoms achalasia of the esophagus, alacrimia and glucocorticoid deficiency as well as multiple other symptoms especially of the nervous system. Report of one case diagnosed in the age of 11.5 years with a case history of about 7 years. Description of the danger to ...

journal_title：Klinische Padiatrie

authors： Hübschmann K

更新日期：1995-05-01 00:00:00

abstract：:A boy aged 4 years and 3 months with Klippel-Trénaunay syndrome showed a vein the thickness of a finger running suprapubicly. When he was standing it was filled tightly. Angiography showed agenesis of the right common femoral vein. Reflux from the right leg passed through this vein to the left common femoral vein. On ...

journal_title：Klinische Padiatrie

authors： Jeschke R,Viehweger G

更新日期：1975-07-01 00:00:00

abstract：:A report was made of three patients who exhibited pronounced heptosplenomegaly at the time of hospital admission: a six-year-old girl and two brothers, 1 year 4 months and 4 years 4 months of age. As is typical for Niemann-Pick disease, foam cells were found in the bone marrow and the liver biopsy specimens for the th...

journal_title：Klinische Padiatrie

authors： Priscu R,Pancu L,Balan A,Petrescu TC,Iacob C

更新日期：1977-11-01 00:00:00

abstract：:Infectious complications are a major cause of morbidity and mortality in pediatric and adult patients undergoing hematopoietic stem cell transplantation. The incidence and the severity code of infections depend on the function of the host's immune system. This function is strongly correlated to the application of immu...

journal_title：Klinische Padiatrie

authors： Schuster FR,Laws HJ

更新日期：2005-11-01 00:00:00

abstract：:This is a case-report about a 4 year old boy with "cherry red" epiglottis, purulent meningitis and pleuropneumonia. Purulent meningitis and pleuropneumonia are not complications of treatment of "cherry red" epiglottis but an entity caused by Hemophilus influenzae-infection and is called Kleinschmidt's syndrome (Hemoph...

journal_title：Klinische Padiatrie

authors： Freudenberg V,Wolf H

更新日期：1976-07-01 00:00:00

abstract：:Case report of arthrogryposis multiplex congenita with histologically proved neutrogene atrophy of muscles. The also existing reduction deformities of the limbs, showing aplasia and hypoplasia of phalanges may hypothetically be of neuropathic origin. ...

journal_title：Klinische Padiatrie

authors： Eckel U,Spranger J,Klein H

更新日期：1979-05-01 00:00:00

abstract：OBJECTIVE:To investigate the change of psychological symptoms and quality of life in children and adolescents with congenital heart disease, cancer, or cystic fibrosis after a family-oriented inpatient rehabilitation program. METHODS:302 participants in the intervention (aged 4-17 years, mean=8.7) were assessed using ...

journal_title：Klinische Padiatrie

authors： Goldbeck L,Hölling I,Schlack R,West C,Besier T

更新日期：2011-03-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of infancy and young childhood. The clinical presentation includes recurrent unexplained fever with hepatosplenomegaly. Cytopenia, hypofibrinogenemia and/or hypertriglyceridemia and hemophagocytosis in bone marrow, spleen and lymphnode confirm the diagnosis. H...

journal_title：Klinische Padiatrie

authors： Dürken M,Schneider EM,Blütters-Sawatzki R,Stollmann-Gibbels B,Nessler G,Bretz R,Körholz D,Probst EN,Holsten-Griffin H,Harps E,Zander AR,Janka GE

更新日期：1998-07-01 00:00:00

abstract：:The aims of trial NHL-BFM 90 for patients (pts) suffering from B-cell neoplasms are to prove whether: 1. Treatment for pts with complete resection can be reduced from 3 to 2 therapy courses; 2. Results for pts of stage III with large abdominal tumors can be improved by high dose (HD) chemotherapy; 3. Survival for pts ...

journal_title：Klinische Padiatrie

authors： Reiter A,Schrappe M,Yakisan E,Sauter S,Ebell W,Zimmermann M,Hartmann W,Kremens B,Kuhn N,Claviez A

更新日期：1994-07-01 00:00:00

abstract：:The GPOH-MAHO trials designed in 3/82 and 7/88 for treatment of childhood testicular germ cell tumors registered 3/92 105 pts. In MAHO 82 study 57 pts. and in MAHO 88 study 48 pts. were treated. Histologically 60% of the tumors revealed yolk sac tumors (YST), 22% teratomas (TD) and 18% malignant teratomas (MTI, MTU, M...

journal_title：Klinische Padiatrie

authors： Haas RJ,Schmidt P,Göbel U,Harms D

更新日期：1993-07-01 00:00:00

abstract：:CML is a rare malignancy in childhood not yet being treated by an established protocol of the Society of Pediatric Oncology and Hematology (GPOH). Up to now only allogeneic bone marrow transplantation (BMT) offers a curative treatment option. After being enrolled into the study "CML-päd" patients with a matched siblin...

journal_title：Klinische Padiatrie

authors： Suttorp M,Lion T,Creutzig U,Klingebiel T,Gadner H

更新日期：1996-07-01 00:00:00

abstract：:The aetiology and pathogenesis of the Duchenne-type muscular dystrophy (pseudohypertrophic muscular dystrophy) are still largely unknown. The possibilities of treating the disease are rather limited. Treatment is the more successful, the earlier diagnosis was possible, and the earlier treatment is initiated. The CK-Sc...

journal_title：Klinische Padiatrie

authors： Beckmann R

更新日期：1978-11-01 00:00:00

abstract：:A case of an infant with a mediastinal neurenteric cyst is used to review this rare entity. By definition a neurenteric cyst is the combination of an entodermal cyst with a vertebral dysplasia. Neurenteric cysts are located in the posterior mediastinum, preferentially on the right side. In a third of the patients thes...

journal_title：Klinische Padiatrie

authors： Köster B,Emons D,Kunath U,Födisch HJ

更新日期：1987-01-01 00:00:00

abstract：:5 patients 10 to 20 months old with severe normochromic, normocytic anemia and reticulocytopenia are reported. All patients recovered within 10 days to 5 weeks. No steroid therapy was given. Failure to recognize the clinical entity leads to unnecessary diagnostic and therapeutic procedures including the transfusion of...

journal_title：Klinische Padiatrie

authors： Schneider H,Jobke A,Niederhoff H,Künzer W

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Peripheral schwannomas and pilomatrixoma are rare clinical features in childhood. The concomitant presence of these tumors in childhood are not described yet. PATIENTS:We describe the first case of a concomitant peripheral benign schwannoma and pilomatrixoma located at the head in a 10-year-old female patie...

journal_title：Klinische Padiatrie

authors： Bittmann S,Ulus H

更新日期：2005-01-01 00:00:00

abstract：:We describe two patients with neuraligic amyotrophia of the shoulder: a 15 year old boy and a girl which was 6 years old at the time of primary manifestation. Mostly adolescent patients are concerned. Beginning is acute, the etiology unclear. The patients initially feel intensive pain in one shoulder, which typically ...

journal_title：Klinische Padiatrie

authors： Weglage J,Kurlemann G

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Epidemiology and resistance patterns of bacterial pathogens in pediatric UTI show large interregional variability and rates of bacterial resistances are changing due to different antibiotic treatment. We intended to evaluate data from northern Germany. PATIENTS AND METHODS:In 100 children (53 female, 47 mal...

journal_title：Klinische Padiatrie

authors： Pape L,Gunzer F,Ziesing S,Pape A,Offner G,Ehrich JH

更新日期：2004-03-01 00:00:00