[The predictive value of the GRF-stimulation test].

Abstract:

:48 patients between one and seventeen years of age were stimulated with GRF (1-29) NH2. Seventeen of them showed a constitutional delay in growth and puberty, twenty-three suffered from growth-hormone deficiency (GHD) and eight had a suspected GHD as a result of pharmacological tests. Although the results demonstrate a high specificity for GH release in children with constitutional delay of growth and patients with functioning hypophyseal gland, the sensitivity for diagnosis of GHD was poor. The majority of GHD patients suffer from hypothalamic disorders and therefore respond to GRF. In conclusion, the GRF-stimulation test may be sufficient for differentiation of hypophyseal or hypothalamic disorders. However, GRF-stimulation test shows too many false positive results in hypothalamic growth disorders and therefore is not recommended for diagnosis of GHD.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Andler W,Eiden S

doi

10.1055/s-2007-1025510

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

157-60

issue

3

eissn

0300-8630

issn

1439-3824

journal_volume

202

pub_type

杂志文章
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  • [Symptoms, Comorbidities and Therapy of Children and Adolescents with Gender Dysphoria].

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  • [Non-Hodgkin's lymphomas in the oropharynx in children - a histological study in 11 patients].

    abstract::In the period from 1965 to 1979 biopsies from the oropharynx of 11 children with non-Hodgkin's lymphoma were collected at the Lymph Node Registry in Kiel. Palatine tonsil tissue was examined in all cases and, in addition, specimens from the retrolingual region of one child and the epipharynx of two patients. All biops...

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    更新日期:1983-05-01 00:00:00

  • [Determination and clinical significance of colloid osmotic pressure in pediatric patients].

    abstract::The clinical significance of colloid osmotic pressure (COP) in transcapillary fluid exchange and water homeostasis in health and disease is described. Under pathophysiological circumstances measurement of COP should be preferred to COP value calculation. After extensive COP experiences in critically ill adults and num...

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    doi:10.1055/s-2008-1034010

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    更新日期:1985-09-01 00:00:00

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  • Diagnosis and Treatment of Nasopharyngeal Carcinoma in Children and Adolescents - Recommendations of the GPOH-NPC Study Group.

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    abstract:BACKGROUND:Essential Thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by excessive production of platelets. The disorder is usually affecting adults and is rarely diagnosed in children. PATIENTS AND METHODS:In this retrospective study we describe 12 children aged 5-16 years in whom E...

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  • [Postoperative sonographic follow-up of brain tumors in childhood].

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  • [Neonatal form of a nonketotic hyperglycinemia in consanguinous parents].

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    doi:10.1055/s-2007-1025473

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    更新日期:1991-11-01 00:00:00

  • [Waardenburg syndrome type I--autosomal dominant hereditary combination of multiple facial anomalies with cochlear deafness (author's transl)].

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    authors: Meinecke P

    更新日期:1982-03-01 00:00:00

  • [Measles epidemic in a highly developed country: low mortality, high morbidity and extensive costs].

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  • [Immunoglobulin and total protein concentrations in saliva of healthy children (author's transl)].

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    doi:10.1055/s-2008-1035623

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  • [Acute spinal syndromes in children and adolescents].

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  • [Therapy of testicular germ cell tumors. Current status of the MAHO studies].

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    doi:10.1055/s-2007-1025231

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    更新日期:1993-07-01 00:00:00

  • [Psychological aspects of radiotherapy of children and adolescents (author's transl)].

    abstract::The increasing importance of radiotherapy in tumor of childhood demands the investigation and consideration of the psychological aspects of this afflicting therapy. In this paper the results obtained by questioning and observing 28 children of different ages, their parents, attendants and employees of several radiolog...

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    doi:10.1055/s-2008-1034457

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  • [Peritonitis and infection in children with idiopathic nephrotic syndrome].

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  • Bloody nipple discharge (BND) in an 8 months old girl and a 9 months old male--rational diagnostic approach.

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    更新日期:2010-03-01 00:00:00

  • [Sonography of the larynx in children. New perspectives due to the use of computerized sonography: 2: Sonographic findings in a case of laryngeal papillomatosis].

    abstract::On our opinion one important indication for sonographic diagnosis in future are masses in the larynx area: in infancy or childhood mainly laryngeal papillomatosis. In one of our boy patients with massive laryngeal papillomatosis laser surgery was first performed at 15 months of age. After a second and third procedure ...

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    pub_type: 杂志文章

    doi:10.1055/s-2007-1025304

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    更新日期:1989-05-01 00:00:00

  • [Influence of nutrition on the cellular defence mechanism (phagocytosis) of preterm and underweight babies during the first six weeks of life (author's transl)].

    abstract::The phagocytic and NBT reduction indices of 94 preterm and underweight babies, divided into 7 groups and two weight classes, were observed over a period of six weeks while they were observed over a period of six weeks while they were given four commercial baby foods (Humana 0, Meb, Multival, Pomil). In all groups the ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

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    更新日期:1978-03-01 00:00:00

  • Leukapheresis and exchange transfusion in children with acute leukemia and hyperleukocytosis. A single center experience.

    abstract:BACKGROUND:The risk of severe complications or death during the initial period of acute leukemia was markedly decreased due to the progress in pediatric oncology and use of simple measures like hyperhydration, forced diuresis, treatment of hyperuricemia, correction of electrolyte and coagulation disturbances and the ca...

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    更新日期:2009-11-01 00:00:00

  • CA 19-9, CA 50 and elastase 1 as additional markers of cystic fibrosis.

    abstract::Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...

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    pub_type: 杂志文章

    doi:10.1055/s-2008-1033692

    authors: Uhlenbruck G,Scheuring U,Dienst C,Kaiser D,Roth B,Skopnik H

    更新日期:1988-03-01 00:00:00

  • [Thyroglossal duct cysts in paediatric patients: early operative intervention reduces rate of complications].

    abstract:BACKGROUND:Thyroglossal duct cysts arise from mucus production in an incomplete regressed thyroglossal duct. Often they are only noticed in case of infection or secondary fistulation. The operative management is a Sistrunk procedure. METHOD AND PATIENTS:In a retrospective study we analyse 26 patients aged 0,3 - 10 yea...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2001-17223

    authors: von Bismarck S,Höllwarth ME

    更新日期:2001-09-01 00:00:00

  • Ceftriaxone alone or in Combination with Teicoplanin in the Management of Febrile Episodes in Neutropenic Children and Adolescents with Cancer on an Outpatient Base.

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    pub_type: 杂志文章

    doi:10.1055/s-2007-1025240

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    更新日期:1993-07-01 00:00:00

  • Clinical outcome of patients with childhood acute lymphoblastic leukaemia and an initial leukaemic blood blast count of less than 1000 per microliter.

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2001-16848

    authors: Lauten M,Stanulla M,Zimmermann M,Welte K,Riehm H,Schrappe M

    更新日期:2001-07-01 00:00:00