Abstract:
OBJECTIVE:This study used a prospective design and the technique of structural modelling to examine the complex interrelations between psychological factors, immune status and complications after major surgery. METHODS:Twenty-nine women scheduled for elective cholecystectomy were studied prospectively. Information regarding medical history, health practices, life stressors, and coping strategies was obtained two weeks prior to admission. At this initial meeting, as well as three days after surgery, and at one month follow-up immunological tests were performed and the level of psychological distress was assessed. The study additionally included measures of post-operative complications, and infections and negative effect during follow-up. RESULTS:Pre-operative immune status emerged as a key variable exerting strong effects on subsequent immune function and, thereby producing significant, indirect effects on every recovery variable. Pre-operative distress was directly linked to increased mood disturbance at follow-up. Moreover, distress significantly influenced immune function both before and after surgery, which mediated a significant impact on most recovery variables. Active coping behaviour directly increased the risk of a complicated recovery. CONCLUSIONS:The study demonstrated that distress-induced changes in immune functioning have clinical relevance. Overall, the present findings suggest that recovery from surgery is facilitated in patients with a well-functioning immune system, a low-level of pre-operative distress and a passive coping disposition.
journal_name
Acta Neuropsychiatrjournal_title
Acta neuropsychiatricaauthors
Vollmer-Conna U,Bird KD,Yeo BW,Truskett PG,Westbrook RF,Wakefield Ddoi
10.1111/j.1601-5215.2009.00398.xsubject
Has Abstractpub_date
2009-08-01 00:00:00pages
169-78issue
4eissn
0924-2708issn
1601-5215pii
S0924270800001198journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to report the frequency of autoimmune disorders and autoantibodies in 22 patients with neuromyelitis optica (NMO), as well as whether the seropositivity for autoantibodies differs between anti-aquaporin 4 (AQP4) positive and AQP4 negative NMO patients. METHODS:Demographic, medical r...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2016.49
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Double depression, the combination of major depression and dysthymia, is associated with poor health-related quality of life (HRQoL) and increased health service utilization. OBJECTIVE:To determine the prevalence of double depression, its associated morbidity and use of health services and antidepressants. ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2006.00153.x
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Female patients with anorexia nervosa differ significantly from the control women in various dimensions of personality. OBJECTIVE:To investigate the personality dimensions measured with the Temperament and Character Inventory (TCI) in adolescent patients with restrictive-type and bulimic/purging-type anorex...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.0924-2708.2004.00073.x
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of transcranially applied pulsed electromagnetic fields (PEMF) on functional impairments and symptom severity in multiple chemical sensitivity (MCS) patients. METHODS:The study was conducted as a nationwide trial in Denmark using a randomised, parallel-group, double-blind and placebo...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章,随机对照试验
doi:10.1017/neu.2016.51
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Sleep disorders are widespread among patients with schizophrenia and contribute to adverse clinical outcomes. Antipsychotic drugs exert varying effects on sleep, and the effects of atypical agents may differ from those of conventional neuroleptics. OBJECTIVE:To review the literature on the effects of atypic...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.0924-2708.2004.00103.x
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:To investigate how individuals with a history of affective disorder use and perceive their use of social media and online dating. METHODS:A questionnaire focusing on affective disorders and the use of social media and online dating was handed out to outpatients from unipolar depression and bipolar disorder ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2020.36
更新日期:2020-10-15 00:00:00
abstract:OBJECTIVE:We investigated whether the nitric oxide (NO) precursor, L-arginine, can prevent the antidepressant-like action of the fast-acting antidepressant, ketamine, in a genetic rat model of depression, and/or induce changes in the glutamate (Glu)/N-methyl-D-aspartate receptor (NMDAR)/NO/cyclic guanosine monophosphat...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2014.39
更新日期:2015-04-01 00:00:00
abstract::Since the description of SAD the prevalence of this disorder has been of particular interest. The more so, because early studies, indicated the correctness of the on theoretical grounds - expected interaction between latitude and prevalence rate of SAD. More eleborate prevalence studies, mainly in the USA indeed showe...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800037546
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVE:To investigate gender differences in psychiatric comorbidity patients diagnosed with attention-deficit hyperactivity disorder (ADHD) as adults. METHODS:Interviews about current ADHD symptoms and psychiatric comorbidity on axis I and II (Structured Clinical Interview for DSM-IV axis I and axis II) were conduc...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2012.00682.x
更新日期:2013-06-01 00:00:00
abstract::Patients with panic disorder (PD) report a transient feeling of anxiety upon inhalation of CO2 enriched air. They rate this experience as similar to symptoms of a panic attack. This hypersensitivity has been proposed as an experimental disease model. This paper examines the validity of single breath inhalation of 35% ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800037030
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:Prisoners categorised as 'dangerous' are a category of prisoners that require and/or force into using special measures of caution, protection and security. The aim of the study was to examine the intensity of anxiety (as a state and as a trait) experienced by officers working with 'dangerous' prisoners and st...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2015.31
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Physical hyperactivity has often been described in anorexia nervosa (AN) patients but up until now in-depth research has been scarce. Experience sampling methodology (ESM), a structured diary technique assessing momentary mental state at random times during the day, may be useful in studying hyperactivity in...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.0924-2708.2006.00121.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:Psychometric research in the field of alcohol dependence has concentrated on identifying certain (personality) characteristics (i.e. typologies). This paper is aimed to identify such typologies and studies the relation of the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and Cloninger's temperament-c...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2007.00188.x
更新日期:2007-08-01 00:00:00
abstract::Depressive syndromes are a group of heterogeneous disorders. Atypical depression (AD) with reversed vegetative signs, such as hyperphagia or hypersomnia, is traditionally neglected, demonstrated by the fact that in the most widely used depression scales, such as the Hamilton Depression Scale (HAMD), melancholic sympto...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2003.00029.x
更新日期:2003-08-01 00:00:00
abstract:UNLABELLED:Scheuch K, Bräunig P, Gauggel S, Kliesow K, Sarkar R, Krüger S. Emotional vulnerability and cognitive control in patients with bipolar disorder and their healthy siblings: a pilot study. OBJECTIVE:There is evidence that, even in remission, patients with bipolar disorder (BD) have deficits in cognitive funct...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2010.00451.x
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Previous studies suggest that brain serotonin neurotransmission may mediate the actions of lithium carbonate. Acute tryptophan depletion (ATD) reduces brain serotonin and allows the study of this neurotransmitter in patient groups. Serotonin modulates electroencephalographic (EEG) activity, which is abnormal...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800035481
更新日期:2000-09-01 00:00:00
abstract::A psychofysiological study of the cardiac adaptivity to attention-demanding reaction time tasks demonstrated that children with a lesser variant of the pervasive developmental disorder (DSM-IV: PDDNOS) exhibit less cardiac responsiveness to attention tasks than healthy children do. We studied changes in heart rate var...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S092427080003605X
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Recognition memory dysfunction has been frequently reported in schizophrenic populations, and has been linked with the development of delusions and thought disorder. A range of neuropsychological abnormalities have also been documented in the biological asymptomatic relatives of patients with schizophrenia; ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2003.00044.x
更新日期:2003-10-01 00:00:00
abstract::Biological schizophrenia research has been dominated by the dopamine hypothesis for decades, but in recent years a more diversified view has gained increasing attention. Several neurotransmitters are now being discussed, and especially their interaction in complex circuitries. The demonstration of an atypical profile ...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800036838
更新日期:1997-06-01 00:00:00
abstract:OBJECTIVE:To investigate oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase (PON), arylesterase (ARE) and thiol-disulphide homeostasis] in patients who were diagnosed as having somatic symptom disorder in accordance with Diagnostic and Stat...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2018.33
更新日期:2018-12-18 00:00:00
abstract:OBJECTIVE:The aims of this study were to determine the dominant affective temperament changes in stroke survivors and whether temperament affects the disability. METHODS:A total of 63 stroke patients were included in this study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire was used to...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2008.00335.x
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Despite various studies, supportive evidence for the efficacy of exercise in treatment of mental illness is still weak. OBJECTIVE:The aim of this study was to compare two forms of exercise, namely running therapy (RT) and physiotraining therapy (PT), on stationary devices. METHODS:Patients in a day treatme...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2006.00115.x
更新日期:2006-06-01 00:00:00
abstract::Objective This study explored the utility of the Health Belief Models (HBM) in explaining medication adherence in subjects with severe affective disorders. Method Well established measuring instruments, with confirmed reliability and validity, were used to assess each component of two HBMs and adherence with mood stab...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800035584
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:Brain-derived neurotrophic factor (BDNF) and S100B are involved in brain plasticity processes and their serum levels have been demonstrated to be altered in patients with psychoses. This study aimed to identify subgroups of patients with psychotic disorders across diagnostic boundaries that show a specific sy...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.59
更新日期:2014-08-01 00:00:00
abstract::Depression is a frequent comorbid disorder of many inflammatory diseases and it is suggested that brain inflammatory processes have a pathogenic role in mood dysregulation. Several immunocompromised patients have been treated with cytokines and long-term treatments have resulted in a variety of neuropsychiatric side-e...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2003.00007.x
更新日期:2003-02-01 00:00:00
abstract::Immunopathogenesis of multiple sclerosis is a complex process involving T cell mediated autoimmunity at initial stage of disease. A long standing view that Th1 cells are critical for early inflammatory development of lesions is challenging by recent findings that Th1 helper cells with Th17 phenotype are even more impo...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/S0924270800032622
更新日期:2009-06-01 00:00:00
abstract::In two previous letters on an selective serotonin reuptake inhibitor (SSRI) meta-analysis conducted by the Copenhagen Trial Unit at Copenhagen University Hospital, we have commented on a large number of errors, almost all of which have tilted the results in an anti-drug direction, that unfortunately mar this publicati...
journal_title:Acta neuropsychiatrica
pub_type: 评论,杂志文章
doi:10.1017/neu.2019.42
更新日期:2020-02-01 00:00:00
abstract::For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1034/j.1601-5215.2002.140206.x
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVE:There is clear evidence of a genetic component in major depression, and several studies indicate that neuropeptide Y (NPY) could play an important role in the pathophysiology of the disease. A well-known polymorphism encoding the substitution of leucine to proline in the signal peptide sequence of NPY (Leu7Pr...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1111/j.1601-5215.2011.00600.x
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVES:Mazindol is a sympathomimetic amine, widely used as an anorectic agent in the treatment of obesity. This drug causes psychostimulant effects because of its pharmacological profile similar to amphetamine, acting like a monoamine reuptake inhibitor. However, the mechanisms underlying the action of mazindol are...
journal_title:Acta neuropsychiatrica
pub_type: 杂志文章
doi:10.1017/neu.2013.43
更新日期:2014-06-01 00:00:00