Exploring a post-traumatic stress disorder paradigm in Flinders sensitive line rats to model treatment-resistant depression II: response to antidepressant augmentation strategies.

abstract：OBJECTIVE:Ginsenosides, biologically-active components of the root of Panax ginseng, have been reported to have therapeutic benefits in a number of disease states including psychiatric conditions such as major depressive disorder. Our objective was to determine if a standardized commercial ginseng extract, G115®, could...

journal_title：Acta neuropsychiatrica

authors： Terstege DJ,MacDonald DS,Tasker RA

更新日期：2021-01-22 00:00:00

abstract：OBJECTIVES:Mazindol is a sympathomimetic amine, widely used as an anorectic agent in the treatment of obesity. This drug causes psychostimulant effects because of its pharmacological profile similar to amphetamine, acting like a monoamine reuptake inhibitor. However, the mechanisms underlying the action of mazindol are...

journal_title：Acta neuropsychiatrica

authors： Gonçalves CL,Scaini G,Rezin GT,Jeremias IC,Bez GD,Daufenbach JF,Gomes LM,Ferreira GK,Zugno AI,Streck EL

更新日期：2014-06-01 00:00:00

abstract：:Objective This study explored the utility of the Health Belief Models (HBM) in explaining medication adherence in subjects with severe affective disorders. Method Well established measuring instruments, with confirmed reliability and validity, were used to assess each component of two HBMs and adherence with mood stab...

journal_title：Acta neuropsychiatrica

authors： Scott J

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:The FATIMA study (FAst TItration of quetiapine fumarate in bipolar I MAnia) evaluated the safety, tolerability and efficacy of a rapid dose escalation of quetiapine in acutely ill bipolar I patients experiencing a manic episode. METHODS:In an open-label, phase II pilot study, 29 patients aged 18 years or old...

journal_title：Acta neuropsychiatrica

authors： Constant E,Seghers A,Ranalli E,Ryckmans V,Snauwaert P,Parent M,Vandenhoven G

更新日期：2009-06-01 00:00:00

abstract：:There has been growing interest in the role of serotonin (5-hydroxytryptamine, 5-HT) in anxiety, including pathological states such as panic disorder. The technique of tryptophan depletion (TD), which causes an acute, temporary and reversible reduction in brain 5-HT levels, is a useful minimally invasive paradigm to a...

journal_title：Acta neuropsychiatrica

authors： Pyle AC,Argyropoulos SV,Nutt DJ

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to determine the dominant affective temperament changes in stroke survivors and whether temperament affects the disability. METHODS:A total of 63 stroke patients were included in this study. Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire was used to...

journal_title：Acta neuropsychiatrica

authors： Kurt E,Karacan I,Ozaras N,Alatas G

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To investigate oxidative stress parameters [total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase (PON), arylesterase (ARE) and thiol-disulphide homeostasis] in patients who were diagnosed as having somatic symptom disorder in accordance with Diagnostic and Stat...

journal_title：Acta neuropsychiatrica

authors： Kabadayi Sahin E,Caykoylu A,Senat A,Erel O

更新日期：2018-12-18 00:00:00

abstract：OBJECTIVE:The aim of the current study was to examine whether and to what extent mood disorders, comprising major depression and bipolar disorder, are accompanied by structural changes in the brain as measured using voxel-based morphometry (VBM). METHODS:We performed a VBM study using a 3Т MRI system (GE Discovery 750...

journal_title：Acta neuropsychiatrica

authors： Kandilarova S,Stoyanov D,Sirakov N,Maes M,Specht K

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:Disturbances in the noradrenergic system, including alterations in the densities of α2-adrenoceptors, are posited to be involved in the pathophysiology of depression. In this study, we investigate the binding of α2-adrenoceptors in regions relevant to depression in an animal model of depression. METHODS:Usi...

journal_title：Acta neuropsychiatrica

authors： Lillethorup TP,Iversen P,Wegener G,Doudet DJ,Landau AM

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:Schizoaffective disorder is a disease with both affective and psychotic symptoms. In this study, we aimed to compare oxidative metabolism markers of schizoaffective disorder, bipolar disorder and schizophrenic patients. Furthermore, we also aimed to investigate whether schizoaffective disorder could be differ...

journal_title：Acta neuropsychiatrica

authors： Bulbul F,Virit O,Alpak G,Unal A,Bulut M,Kaya MC,Altindag A,Celik H,Savas HA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To review the literature comparing electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) for major depression. METHODS:Data from the six randomised, prospective studies were agglutinated into one data set. Special attention was given to the methods of both TMS and ECT as well as data pe...

journal_title：Acta neuropsychiatrica

authors： Rasmussen KG

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Recent observations demonstrate a significant ameliorative effect of add-on transcranial direct current stimulation (tDCS) on auditory verbal hallucinations (AVHs) in schizophrenia. Of the many SNPs, NRG1 rs35753505 and catechol-o-methyl transferase (COMT) rs4680 polymorphisms have shown to have a strong asso...

journal_title：Acta neuropsychiatrica

authors： Chhabra H,Shivakumar V,Subbanna M,Kalmady SV,Bose A,Agarwal SM,Sreeraj VS,Dinakaran D,Narayanaswamy JC,Debnath M,Venkatasubramanian G

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Physical hyperactivity has often been described in anorexia nervosa (AN) patients but up until now in-depth research has been scarce. Experience sampling methodology (ESM), a structured diary technique assessing momentary mental state at random times during the day, may be useful in studying hyperactivity in...

journal_title：Acta neuropsychiatrica

authors： Pieters G,Vansteelandt K,Claes L,Probst M,Van Mechelen I,Vandereycken W

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to analyse demographic and clinical characteristics, as well as psychiatric diagnoses to identify gender differences in patients with attempted suicide in a Mexican population. METHODS:Between September 2010 and September 2012, 140 suicide attempts were documented in the Depa...

journal_title：Acta neuropsychiatrica

authors： Fresán A,González-Castro TB,Peralta-Jiménez Y,Juárez-Rojop I,Pool-García S,Velázquez-Sánchez MP,López-Narváez L,Tovilla-Zárate CA

更新日期：2015-06-01 00:00:00

abstract：UNLABELLED:Scheuch K, Bräunig P, Gauggel S, Kliesow K, Sarkar R, Krüger S. Emotional vulnerability and cognitive control in patients with bipolar disorder and their healthy siblings: a pilot study. OBJECTIVE:There is evidence that, even in remission, patients with bipolar disorder (BD) have deficits in cognitive funct...

journal_title：Acta neuropsychiatrica

authors： Houshmand K,Bräunig P,Gauggel S,Kliesow K,Sarkar R,Krüger S

更新日期：2010-04-01 00:00:00

abstract：:In two previous letters on an selective serotonin reuptake inhibitor (SSRI) meta-analysis conducted by the Copenhagen Trial Unit at Copenhagen University Hospital, we have commented on a large number of errors, almost all of which have tilted the results in an anti-drug direction, that unfortunately mar this publicati...

journal_title：Acta neuropsychiatrica

authors： Hieronymus F,Lisinski A,Näslund J,Eriksson E

更新日期：2020-02-01 00:00:00

abstract：:BACKGROUND: Aberrant electrophysiological and hemodynamic processing of auditory oddball stimuli is among the most robustly documented findings in patients with schizophrenia. However, no study to date has directly examined linked patterns of electrical and hemodynamic differences in patients and controls. METHODS: I...

journal_title：Acta neuropsychiatrica

authors： Calhoun V,Wu L,Kiehl K,Eichele T,Pearlson G

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Schizophrenia is consistently associated with lower IQ compared to the IQ of control groups, or estimated premorbid IQ. It is not likely that the IQ scores deteriorate during the prodromal phase or first psychotic episode; they are already present before the onset of the prodromal phase and have been detecte...

journal_title：Acta neuropsychiatrica

authors： van Beilen M,Withaar F,van Zomeren AH,van den Bosch R

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy of transcranially applied pulsed electromagnetic fields (PEMF) on functional impairments and symptom severity in multiple chemical sensitivity (MCS) patients. METHODS:The study was conducted as a nationwide trial in Denmark using a randomised, parallel-group, double-blind and placebo...

journal_title：Acta neuropsychiatrica

authors： Tran MTD,Skovbjerg S,Arendt-Nielsen L,Christensen KB,Elberling J

更新日期：2017-10-01 00:00:00

abstract：:The alterations in the inflammatory response system (IRS) appear to be quite different between OCD and anorexia nervosa and are also different from the changes observed in major depression. In anorexia nervosa, there is some evidence for increased production of monocytic cytokines, i.e. tumor necrosis factor-α (TNFα) ...

journal_title：Acta neuropsychiatrica

authors： van West D,Maes M

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:This study aimed to explore effects of adjunctive treatment with N-acetyl cysteine (NAC) on markers of inflammation and neurogenesis in bipolar depression. METHODS:This is a secondary analysis of a placebo-controlled randomised trial. Serum samples were collected at baseline, week 8, and week 32 of the open-...

journal_title：Acta neuropsychiatrica

authors： Panizzutti B,Bortolasci C,Hasebe K,Kidnapillai S,Gray L,Walder K,Berk M,Mohebbi M,Dodd S,Gama C,Magalhães PV,Cotton SM,Kapczinski F,Bush AI,Malhi GS,Dean OM

更新日期：2018-12-01 00:00:00

abstract：:A huge number of natural and synthetic compounds modulate the function of the γ-aminobutyric acid type A receptor (GABAA-R) by interacting with several allosteric binding sites which may differ in the various GABAA-R subtypes. The benzodiazepine receptor (BDZ-R) is the most intensively studied allosteric site. It is t...

journal_title：Acta neuropsychiatrica

authors： Vermeulen PJ,Zitman FG

更新日期：2000-03-01 00:00:00

abstract：:A psychofysiological study of the cardiac adaptivity to attention-demanding reaction time tasks demonstrated that children with a lesser variant of the pervasive developmental disorder (DSM-IV: PDDNOS) exhibit less cardiac responsiveness to attention tasks than healthy children do. We studied changes in heart rate var...

journal_title：Acta neuropsychiatrica

authors： Althaus M,Aarnoudse CC,Mulder LJ,Mulder G,Minderaa RB

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVE:Fas (CD95), commonly categorised as a death receptor due to its well-defined role in apoptosis, can paradoxically also promote neuroprotection. We have previously found that defects in Fas signalling render mice highly susceptible to neural degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mous...

journal_title：Acta neuropsychiatrica

authors： Landau AM,Siegrist-Johnstone R,Desbarats J

更新日期：2012-06-01 00:00:00

abstract：UNLABELLED:Jones MP, Bartrop RW, Forcier L, Penny R. The long-term impact of bereavement upon spouse health: a 10-year follow-up. OBJECTIVES:This study is the first to examine the effect of bereavement of a first-degree family member on subsequent morbidity over a 10-year follow-up period. METHODS:A sample of bereave...

journal_title：Acta neuropsychiatrica

authors： Jones MP,Bartrop RW,Forcier L,Penny R

更新日期：2010-10-01 00:00:00

abstract：:In the training program for residents in psychiatry, scientific education and participation in research projects are relatively underdeveloped. This may result in a gap between recently acquired scientific knowledge and its implementation in clinical practice. Since the start of the residency training in psychiatry in...

journal_title：Acta neuropsychiatrica

authors： Verhoeven WM,Goessens LF,van den Berg YW,Tuinier S

更新日期：1999-03-01 00:00:00

abstract：:Most forms of behaviour whether normal or abnormal, show a tendency to run in families. However, these can range from symptoms of dementia and movement disorder caused by the comparatively rare autosomal dominant Huntington's disease to common everyday aspects of behaviour such as religious persuasion or career choice...

journal_title：Acta neuropsychiatrica

authors： McGuffin P

更新日期：1999-06-01 00:00:00

abstract：:For more than 20 years, patients with borderline personality disorder have been treated as in-patients in the UC St-Jozef in Kortenberg, Belgium. The majority of these patients were treated in a psychoanalytical or a behavior therapy ward. During these years, the treatment programs of these wards were gradually adjust...

journal_title：Acta neuropsychiatrica

authors： Pieters G,Vermote R

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Studies on the determinants of the quality of life (QOL) after stroke bring differing results depending on the applied concept of QOL. This may lead to confusion about the contribution of various factors to the post-stroke QOL. OBJECTIVE:The aim of the study was: (i) to investigate functional and psychologi...

journal_title：Acta neuropsychiatrica

authors： Jaracz K,Jaracz J,Kozubski W,Rybakowski JK

更新日期：2002-10-01 00:00:00

abstract：:In the past decade, neuroimaging research has identified key components in the neural system that underlies bipolar disorder (BD). The ventral prefrontal cortex (VPFC) and amygdala are highly interconnected structures that jointly play a central role in emotional regulation. Numerous research groups have reported prom...

journal_title：Acta neuropsychiatrica

authors： Womer FY,Kalmar JH,Wang F,Blumberg HP

更新日期：2009-09-23 00:00:00