Abstract:
OBJECTIVE:To evaluate the use of umbilical cord blood culture (UCBC) as compared to neonatal blood culture (NBC) in the diagnosis of early onset neonatal sepsis (EONS). METHODS:This hospital based prospective observational study was conducted in the Department of Pediatrics and Department of Obstetrics & Gynaecology at a tertiary care centre of North India from 2017 through 2018. A total of 80 newborns with presence of two or more risk factors for sepsis were included in the study. Blood culture samples were collected from the umbilical cord at delivery and from the neonate within 1 h of birth. RESULTS:UCBC was positive in 17 (21.2%) neonates and NBC was positive in 15 (18.7%) neonates. Out of these positive cases, 10 (45.4%) neonates had similar bacteriological profile in both UCBC and NBC which included Burkholderia cepacia, Acinetobacter species, Enterobacter cloacae and Coagulase-negative Staphylococcus. UCBC had a sensitivity of 66.7%, a specificity of 89.2%, a positive predictive value 58.8% and a negative predictive value 92.1% for the diagnosis of EONS in high risk neonates, considering NBC as the gold standard test. CONCLUSIONS:UCBC is a reliable alternative to NBC for early etiological diagnosis of EONS in high risk neonates. Additional blood sampling from the newborn is suggested if there is any clinical sign of sepsis.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Meena R,Meena KK,Athwani V,Gothwal S,Bairwa GS,Sitaraman Sdoi
10.1007/s12098-020-03345-5subject
Has Abstractpub_date
2020-10-01 00:00:00pages
793-797issue
10eissn
0019-5456issn
0973-7693pii
10.1007/s12098-020-03345-5journal_volume
87pub_type
杂志文章abstract::Malaria is essentially a local and focal disease since its transmission depends greatly on local eco-environmental conditions. In India, the incidence of total malaria cases has been contained to around 2-3 million cases per year. However, with the occurrence of outbreaks in different parts of the country since 1994, ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02727167
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVES:To identify the problems faced by parents of children with developmental disabilities in availing rehabilitative services and to find their satisfaction level. METHODS:This study was carried out at a Child Development Clinic (CDC) located in Northern India. Children with developmental disabilities, who were...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0653-0
更新日期:2012-09-01 00:00:00
abstract::The leukodystrophies are familial disorders with onset usually in infancy or childhood. The clinical features consist of motor dysfunction with varying degree of cognitive decline. Magnetic Resonance Imaging (MRI) has helped to identify and characterize these disorders. In some leukodystrophies, biochemical enzymatic ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02724013
更新日期:2005-04-01 00:00:00
abstract::Oral lesions of tuberculosis though uncommon, are seen both in the primary as well as the secondary stages of the disease. In secondary tuberculosis, the oral manifestations are accompanied by lesions in the lung, lymph nodes, or any other organ system of the body. This can be detected by the usual clinical history an...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0266-z
更新日期:2011-03-01 00:00:00
abstract::Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are disorders of pulmonary inflammation characterized by hypoxemia and respiratory failure. Children have varying incidence of ALI/ARDS from 2.2 to 16 per 100,000 pediatric population associated with high morbidity, mortality, and financial burden....
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0169-z
更新日期:2010-11-01 00:00:00
abstract::We studied 2447 asymptomatic school children by microscopic examination of urine and culture of a clear voided midstream specimen of urine. Only three children had bacteriuria (0.12%). Urographic abnormalities were detected in both the cases, which could be investigated. This study has shown that asymptomatic bacteriu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02749724
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To evaluate genetic variations of innate immune system such as mannose binding lectin (MBL), Toll like receptor 4 (TLR4), CD14, LY96 (MD2) and Uroplakin 1B (UPK1B) genes in children with recurrent urinary tract infection (UTI). METHODS:The study included 30 children with recurrent UTI and 30 healthy controls...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0399-8
更新日期:2011-10-01 00:00:00
abstract::Primary vesicoureteric reflux (VUR) is the most common inherited structural urinary tract disorder, conforming closely to autosomal dominant transmission. A pair of monozygotic siblings is described exhibiting a remarkably parallel clinical course. VUR grade II was diagnosed in girl A during urinary tract infection at...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-008-0061-2
更新日期:2008-03-01 00:00:00
abstract::Superior mediastinal syndrome (SMS) is an uncommon manifestation of malignant neoplastic disease in children. The commonest neoplastic cause of SMS is Non Hodgkin lymphoma. Acute myeloid leukemia (AML) as a cause of SMS is extremely uncommon in childhood. The authors hereby report a case of a child with AML who presen...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0799-4
更新日期:2013-02-01 00:00:00
abstract::"Hypertensive" variant of congenital adrenal hyperplasia is rare. The authors describe an interesting case of a 6-y-old boy who presented with an acute respiratory illness and progressive breathlessness since 1 y. Genital hyperpigmentation was noticed since 2 y of age; the onset of pubarche and increasing penile size ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0649-9
更新日期:2012-09-01 00:00:00
abstract::Harlequin fetus is the severe form of congenital ichthyosis. There are very few reports of babies with this condition surviving the first few weeks of life. We treated two siblings who lived for 22 months and six weeks respectively. We started treatment with oral etretinate every early in their lives and achieved good...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02752311
更新日期:1998-03-01 00:00:00
abstract::Since the classic description of this disease by Harold Hirschsprung's. In 1886 just over a century ago, there has been a marked evolution in the diagnostic modalities, understanding of the pathophysiology, unraveling of genetic association and the treatment approach of this disease. Recent research on the molecular b...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02758486
更新日期:2000-08-01 00:00:00
abstract:OBJECTIVE:To identify the causes and contributing factors of persistent pneumonia in children. METHODS:41 cases with persistent pneumonia were investigated (biochemical, microbiological, histopathological, immunological and radiological tests) to find out the underlying cause. RESULTS:Out of 41 cases, 8 had pulmonary...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0272-1
更新日期:2009-12-01 00:00:00
abstract::Teratomas form the most common type of congenital brain tumors, frequently presenting as stillbirth. The largest neonatal series of intracranial teratomas reported a 12% survival rate. Although the first teratoma of the lateral ventricle was reported in 1961 by Maier, neonatal intracranial teratoma of the lateral vent...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-010-0039-8
更新日期:2010-04-01 00:00:00
abstract::Fevers in children are mainly due to infection, malignancy or inflammatory conditions. Rheumatologists have an important role in the care of inflammatory conditions, many of which are associated with fevers. Seven conditions, the hereditary recurrent fever syndromes, have been defined with the presenting symptom of re...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0206-y
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To compare the insertion characteristics, utilization profile, life span and the complication rates of Central lines (CL) and Peripherally inserted central lines (PICL). METHODS:A prospective study of all CL or PICL insertions during January 2007 to September 2007 in the Neonatal Surgical Intensive Care Unit...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0291-y
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To measure the economic output/input ratios for the various options of prevention of rheumatic fever/rheumatic heart disease (RF/RHD) and check the viability of primary prevention vis-à-vis secondary and tertiary preventions. METHODS:Cost accounting of the various prevention options was calculated for each v...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-007-0094-y
更新日期:2007-06-01 00:00:00
abstract::The Caudal dysplasia syndrome (CDS) and the femoral hypoplasia-unusual facies syndrome (FHUFS) have been reported to be more frequent among infants of diabetic mothers (IDMs). Infact, uncontrolled maternal diabetes is the most common cause of both the syndromes. Till now, there is no case report to suggest absent radi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0650-3
更新日期:2012-11-01 00:00:00
abstract::The aim of the study was to assess the functional aspects and the staffing at Pulse Polio immunisations posts. Interns and medical students conducted the survey in eighty seven pulse polio immunisation posts scattered all over National Capital Territory of Delhi on 18th January 1997. A pre-tested structured format con...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02730902
更新日期:1998-07-01 00:00:00
abstract::Hypothyroidism and type 1 diabetes mellitus (T1DM) constitute two common endocrine disorders of children. Both these are chronic conditions which require long term follow-up for optimum control, can be missed on initial presentation unless a high index of suspicion is maintained and may be associated with adverse outc...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1101-0
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the social consequences of dialysis on children and their parents. METHODS:From January through June 2012 short structured interviews with parents or caregivers of children on peritoneal dialysis (PD) or hemodialysis (HD) who were followed up at King Abdulaziz University Hospital, King Faisal Sp...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1236-z
更新日期:2014-10-01 00:00:00
abstract::Two cases with macroscopic hematuria as complication of acute mumps infection is reported. The patients have neither been vaccinated against mumps nor had mumps infection earlier. Macroscopic hematuria resolved spontaneously and renal functions did not deteriorate in both the patients. Although mumps has a benign cour...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722752
更新日期:2003-01-01 00:00:00
abstract::Secondary Moyamoya disease, also known as Moyamoya syndrome has been rarely associated with Down syndrome. In pediatric patients, the usual presentation is that of ischemic stroke. Here is reported a 4-year-old child with Down syndrome and Moyamoya syndrome who presented with acute-onset right hemiplegia. A high index...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02724192
更新日期:2005-07-01 00:00:00
abstract::This study was conducted in children under the age of four years for a period of one year. By domiciliary visits the diarrheal episodes were recorded, analysed and presented. The findings are based on the diarrheal experience of 4860 children. The attack rate was 2.6/child/year. Family with more than one child had mor...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751121
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:To study the prevalence of celiac disease in Indian children with Down syndrome and evaluate its clinical and laboratory predictors. METHODS:Prevalence of celiac disease (CD) was assessed in 100 patients with Down syndrome (DS) attending pediatric genetic clinic at All India Institute of Medical Sciences,in ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0838-1
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:To determine the correlation between various obesity indices and pulmonary function parameters in obese Thai children and adolescents. METHODS:Obese children and adolescents aged from 8 to 18 y and diagnosed under the criteria of International Obesity Task Force (IOTF) were enrolled. Anthropometric and body ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-015-1777-4
更新日期:2015-12-01 00:00:00
abstract::Essential fatty acids cannot be synthesized in the body but they are required for maintenance of optimal health. There are two classes of polyunsaturated fatty acids (PUFAs)--omega-6 and omega-3. The parent omega-6 fatty acid, linoleic acid (LA) is desaturated in the body to form arachidonic acid while parent omega-3 ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU). METHODS:A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at l...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1415-6
更新日期:2014-11-01 00:00:00
abstract::Assay of hexosaminidase A and B enzymes in four cases with developmental regression and cherry red spot on fundus examination confirmed that three cases had Tay-Sachs disease, and one case had Sandhoff disease. Prenatal diagnosis was carried out by hexosaminidase enzyme assay in amniotic fluid and cells in one family,...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02755072
更新日期:1995-07-01 00:00:00
abstract::The natural history of the univentricular physiology is determined primarily by the presence (severity) or absence of obstruction to pulmonary blood flow and secondarily by the single ventricular cardiomyopathy that develops in response to chronic volume overload. Important obstruction to pulmonary blood flow will aff...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02760487
更新日期:2000-07-01 00:00:00