Abstract:
:"Hypertensive" variant of congenital adrenal hyperplasia is rare. The authors describe an interesting case of a 6-y-old boy who presented with an acute respiratory illness and progressive breathlessness since 1 y. Genital hyperpigmentation was noticed since 2 y of age; the onset of pubarche and increasing penile size at 4 y. He was admitted in congestive cardiac failure with a blood pressure of 150/100 mm Hg. Facial acne; slight facial, pubic hair and penile enlargement were additionally noted. Chest radiograph revealed cardiomegaly. Basal ACTH and 17-OHP levels were high. A diagnosis of congenital adrenal hyperplasia (11β-hydroxylase deficiency) was made due to hypertension with virilized genitalia. Cardiac failure was controlled with fluid restriction and diuretics; he was started on prednisolone, spironolactone and nifedipine. This case is presented for its rarity where hypertension can cause complication of cardiac failure, if diagnosis is delayed despite early features of pseudoprecocious puberty.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Bhatia S,Muranjan MN,Lahiri KRdoi
10.1007/s12098-011-0649-9subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1241-3issue
9eissn
0019-5456issn
0973-7693journal_volume
79pub_type
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journal_title:Indian journal of pediatrics
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pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2008-05-01 00:00:00
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更新日期:2006-03-01 00:00:00
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更新日期:2009-02-01 00:00:00
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