Abstract:
OBJECTIVES:To identify risk factors and outcomes associated with early failure of nasal continuous positive airway pressure (CPAP) in premature infants with respiratory distress (RD). METHODS:This is a retrospective observational study of all the preterm infants with RD primarily supported on nasal CPAP and included in CPAP trials conducted at the study site. Data was collected from the raw excel sheets of the previous trials but limited to eligible patients from study site. Early CPAP failure was defined as the need for mechanical ventilation in the first 72 h after birth. Predictor variables for CPAP failure included baseline maternal and infant characteristics, CPAP care practices, morbidities and adjuvant therapies. The morbidities and outcomes were compared among infants with CPAP failure and CPAP success. RESULTS:Six hundred and fifty-two infants were enrolled in the study. Early CPAP failure was seen in 96 infants (14.7%, 95% CI: 12%-17.5%). On logistic regression, adjusting for gestation and year of study, time of starting CPAP in hours (OR 1.01, 95% CI: 1.003-1.013), time of surfactant administration in hours (OR 1.12, 95% CI: 1.05-1.19), InSurE (Intubate Surfactant Extubate) (OR 2.7, 95% CI: 1.43-5.06) and higher starting FiO2 (OR 1.03, 95% CI: 1.01-1.05) predicted early CPAP failure. Neonatal morbidities and hospital duration were significantly higher in infants who failed CPAP. CONCLUSIONS:Early starting of CPAP, InSurE, early surfactant administration, lower CPAP pressures and lower FiO2 at starting of CPAP were the important determinants of success.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Murki S,Kandraju H,Oleti T,Saikiran,Gaddam Pdoi
10.1007/s12098-020-03399-5subject
Has Abstractpub_date
2020-11-01 00:00:00pages
891-896issue
11eissn
0019-5456issn
0973-7693pii
10.1007/s12098-020-03399-5journal_volume
87pub_type
杂志文章abstract::This study reports the clinical picture and measles virus antibody titres in 32 patients with cases of suspected subacute sclerosing panencephalitis (SSPE). The history of myoclonic jerks, mental regression, inability to walk and slurred speech, were noted in these cases. The EEG showed generalised periodic complexes ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02825445
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:To assess performance of WHO 2006 standards on anthropometric measurements of children referred for growth related disorders to a speciality pediatric clinic in Pune, India, from June 2006 through June 2010. METHODS:Data presented in this study were collected retrospectively from case records of all children...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0687-y
更新日期:2012-07-01 00:00:00
abstract::Two cases with macroscopic hematuria as complication of acute mumps infection is reported. The patients have neither been vaccinated against mumps nor had mumps infection earlier. Macroscopic hematuria resolved spontaneously and renal functions did not deteriorate in both the patients. Although mumps has a benign cour...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722752
更新日期:2003-01-01 00:00:00
abstract::Hypocalcemia is a rare, but reversible, cause of congestive heart failure. We report a 4-month-old boy diagnosed as dilated cardiomyopathy who had prolonged QoTc with low blood levels of calcium, normal phosphate, elevated alkaline phosphatase and findings suggestive of rickets. In view of non response to calcium and ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723209
更新日期:2001-03-01 00:00:00
abstract:OBJECTIVE:Group A beta hemolytic streptococcus (GAS) sore throat primarily occurs among children in 5-15 years age group, and if not treated appropriately causes rheumatic fever/rheumatic heart disease (RF/RHD). Present study was aimed at validation of a clinical scoring system for diagnosis of GAS. METHODS:Five hundr...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722644
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVE:To study the iron profile and find out an accurate diagnostic tool which reflects iron status in different types of infection in severely malnourished children aged 12 months to 71 months. METHODS:Hundred and Eight (108) children of whom 72 children were infected and 36 non infected severely malnourished chi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0098-x
更新日期:2009-09-01 00:00:00
abstract::We present a 10-year-old girl who presented to our emergency services with difficulty in breathing of 2-days duration and progressive weakness of a month's duration. In a previous admission elsewhere, she had not been detected to have hyperthyroidism or electrolyte abnormalities. On admission, the child was in hyperca...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-007-0194-8
更新日期:2007-11-01 00:00:00
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journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03653-w
更新日期:2021-01-09 00:00:00
abstract:OBJECTIVE:To compare the lipid profile of exclusively breastfed and mixed-fed, term, appropriate for gestation age infants from 6 mo to 1 y of age. METHODS:This prospective comparative study included one hundred ninety nine consecutive term healthy infants; 105 on exclusive breastfeeding (EBF) and 94 receiving mixed f...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1580-7
更新日期:2015-04-01 00:00:00
abstract::Fevers in children are mainly due to infection, malignancy or inflammatory conditions. Rheumatologists have an important role in the care of inflammatory conditions, many of which are associated with fevers. Seven conditions, the hereditary recurrent fever syndromes, have been defined with the presenting symptom of re...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-010-0206-y
更新日期:2010-10-01 00:00:00
abstract::Among the 500 Down syndrome children karyotyped, 15 (3%) were due to translocation; 10 were 21;21 translocation and five 14;21. There were 9 cases of de novo translocations, while 6 were inherited from father or mother. Family history was characteristic in all the translocation cases, with younger parental age, fetal ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722100
更新日期:1990-03-01 00:00:00
abstract::Juvenile dermatomyositis and juvenile scleroderma are rare multisystem autoimmune disorders. Although they share some pathognomonic hallmarks with adult onset myositis or scleroderma, there are significant differences in presentation, characteristics and associated features when the diseases present in childhood. In v...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-015-1907-z
更新日期:2016-02-01 00:00:00
abstract::Interpersonal communication between pediatricians and mothers is both complex and interdependent. The mother is dependent on the pediatrician for her child's wellbeing and care along expertise-related dimensions for which she cannot provide. The pediatrician is dependent on the mother's ability to provide accurate inf...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-012-0934-2
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To develop a height and weight based equation to estimate total body water (TBW) in Sri Lankan children. METHODS:Cross sectional descriptive study done involving 5-15 year old healthy children. Height and weight were measured. TBW was assessed using isotope dilution method (D(2)O) and fat free mass (FFM) cal...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0333-5
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To assess Ankle-Foot-Orthosis (AFO) requirement and ambulation in Duchenne Muscular Dystrophy (DMD) patients seen over a period of 4 y at a multi-disciplinary Neuromuscular disorders clinic (NMD). METHODS:A study was conducted in university quaternary research hospital with DMD patients confirmed by MLPA (mu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2251-7
更新日期:2017-03-01 00:00:00
abstract::A 5-year-old child presented with the second episode of meningitis when we started investigating her to find a cause for recurrent episode of meningitis. During this she suffered from a third attack after which she was diagnosed as having isolated C(3) deficiency. She was put on penicillin prophylaxis and vaccinated a...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0036-y
更新日期:2009-01-01 00:00:00
abstract::In a prospective study of 1,053 consecutive children who attended the Rheumatic Care Centre, Government General Hospital, Madras from 1991 to 1995, 331 children fulfilled the criteria proposed by the American Rheumatism Association as modified by Cassidy et al for the diagnosis of Juvenile Rheumatoid Arthritis. These ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02905724
更新日期:1996-07-01 00:00:00
abstract::The aim of the study was to assess the functional aspects and the staffing at Pulse Polio immunisations posts. Interns and medical students conducted the survey in eighty seven pulse polio immunisation posts scattered all over National Capital Territory of Delhi on 18th January 1997. A pre-tested structured format con...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02730902
更新日期:1998-07-01 00:00:00
abstract:OBJECTIVES:To compare the clinical profile and short-term outcome of children with axonal and demyelinating subtypes of childhood Guillain Barré syndrome (GBS). METHODS:This is a prospective observational study conducted in a tertiary care teaching hospital in North India. Consecutive children with Guillain Barré synd...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2835-5
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVES:To compare parent reported sleep behaviors of children with Autism Spectrum Disorders (ASD) and normal healthy controls and to examine the association of sleep disturbances with daytime behavioral difficulties in children with ASD. METHODS:Sixty ASD children (85% boys) (Mean age=6.1 y, SD=2.4) were recruite...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2731-z
更新日期:2019-01-01 00:00:00
abstract::Malaria is essentially a local and focal disease since its transmission depends greatly on local eco-environmental conditions. In India, the incidence of total malaria cases has been contained to around 2-3 million cases per year. However, with the occurrence of outbreaks in different parts of the country since 1994, ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02727167
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:The present study was conducted to evaluate physical growth and nutritional status of 214 school-going girls ranging in age from 5 to 12 years of rural area in Pauri Garhwal district of Uttaranchal. METHODS:Physical growth was evaluated using eleven standard anthropometric measurements viz., height, body wei...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02724181
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To identify pathogens responsible for acute severe lower respiratory tract infection (ALRTI) in under five children by non-invasive methods. METHOD:95 children hospitalized with acute severe lower respiratory tract infection were investigated for identification of viruses, bacteria, chlamydia or mycoplasma b...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722742
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To investigate correlations between anthropometrics and body composition with bone parameters of the whole-body and lumbar spine in non-obese and obese Thai female adolescents. METHODS:This study was performed in 135 female adolescents aged 15 to 18 y enrolled in secondary schools in southern Thailand. Subje...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-017-2422-1
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To find out various life stressors of adolescents, coping strategies adopted by them and the impact of stress on adolescent mental health. METHODS:A descriptive, cross sectional study was conducted in the schools in south zone of Delhi, capital city of the country. Data was collected on 360 adolescents betwe...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-015-1710-x
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVES:To establish a technique for mutation identification and prenatal screening in confirmed cases of Canavan disease. METHOD:Mutations in ASPA gene were identified by sequencing. Six exons of ASPA gene were amplified using intronic primers flanking the exons and then sequenced on ABI 3500Dx automated unit. Thi...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-012-0862-1
更新日期:2013-01-01 00:00:00
abstract::This article aims to describe the National Family Health Survey (NFHS) being carried out in India with its first round during 1992-93 (NFHS-I) and second round during 1998-99 (NFHS-II), with special reference to information available in relation to children. The survey was on lines of the existing systems of Demograph...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722355
更新日期:2001-11-01 00:00:00
abstract::Achalasia is rare in children, more so familial. We report two siblings with familial achalasia who presented in their infancy with vomiting and failure to thrive. Achalasia can be misdiagnosed as upper gastrointestinal obstruction as happened in one of our siblings. Esophageal contrast roentgenography is diagnostic. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02762120
更新日期:2001-09-01 00:00:00
abstract::Immunoglobulin isotypes (IgG, IgA, IgM, IgD, IgE) in serum were investigated in 64 Libyan children with mild to moderately severe asthma (age: 1-12 years; sex: 39 males, 25 females) (Group A) and in 57 healthy Libyan children (age: 1-12 years; sex: 30 males, 27 females (Group B). The patients were classified according...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02845519
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To compare oral co-amoxiclav with injectable ampicillin and amikacin for the management of asymptomatic neonates born to mothers with risk factors for infection. METHODS:This open label, randomized controlled trial was conducted in a tertiary care teaching hospital on neonates of gestational age ≥ 34 wk with...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03412-x
更新日期:2020-10-01 00:00:00